Summary
F-MRI in recent years has been shown to be an adequate method to study brain activation and carries a number of advantages over PET, especially in terms of spatial and temporal resolution. Even though unsolved methodiological issues exist, valuable clinical application has been demonstrated. Thus, a greater clinical impact than that seen with PET is predicted, mainly because of lack of invasiveness. Hence, repeatability and availability should be possible for a much larger patient group considering the number of MR installations worldwide. Its main applications today consist in visualization of motor and language areas as part of the preoperative evaluation of patients with brain tumors. More complex activation paradigms are under evaluation and may prove helpful to understand the role of those brain regions previously thought to be nonloquent. Other perspectives can be foreseen in the objective assessment of neurological deficits in uncooperative patients pre- and postoperatively and in studies of functional reorganization and possibly plasticity in destructive brain lesions. Finally, the question arises of whether the expected exponential data accumulation from human brain mapping studies can be reintegrated to provide a meaningful understanding of the complexity of human brain function.
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Auer, D., Auer, L.M. (1998). Functional Magnetic Resonance Imaging in Clinical Neuroscience: Current State and Future Prospects. In: Hellwig, D., Bauer, B.L. (eds) Minimally Invasive Techniques for Neurosurgery. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-58731-3_40
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DOI: https://doi.org/10.1007/978-3-642-58731-3_40
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