Zusammenfassung
Die Möglichkeit, Reagenzien (zum Teil bereits in Form von„Kits“) kommerziell zu erwerben, Maßnahmen zur Steigerung der Sensitivität und die Adaptation der Methoden zum Einsatz an konventionell fixiertem und eingebettetem Untersuchungsmaterial gewährleisten breite Anwendbarkeit auch in Laboratorien ohne Spezialeinrichtungen, aber auch gute Korrelation immunhistochemischer Ergebnisse mit lichtmikroskopischen Befunden.
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Literatur
Adams JC (1992) Biotin amplification of biotin and horseradish peroxidase signals in histochemical stains. J Histochem Cytochem 40:1457–1463
Bancroft JD, Stevens A (Eds) (1996) Theory and practice of histological techniques. 4th Edn, Churchill Livingstone, New York, Edinburgh, London, Madrid, Melbourne, San Francisco, Tokyo
Bankfalvi A, Navabi H, Bier B, Böcker W, Jasami B, Schmid KW (1994) Wet autoclave pretreatment for antigen retrieval in diagnostic immunohistochemistry. J Pathol 174:223–228
Bankfalvi A, Riehemann K, Öfner D, Checci R, Morgan JM, Piffko J, Böcker W, Jasani B, Schmid KW (1994) Feuchtes Autoklavieren. Der einfachere Weg zur Antigen-demaskierung. Pathologe 15:345–349
Becker T, Becker KF, Röhrl MH, Höfler H (1997) Laserassisted preparation of single cells from stained histological slides for gene analysis. Histochem Cell Biol 108:447–451
Bertino B, Knape WA, Pytlinska M, Strauss K, Hammou JC (1994) A comparative study of DNA content as measured by flow cytometry and image analysis in 1864 specimens. Anal Cell Pathol 6:377–394
Böcking A (1990) DNA-Zytometrie und Automation in der klinischen Diagnostik. Beitr Onkol 38:298–347
Böcking A (1995) DNA measurements. When and why? Comp Qual Assurance, Proficiency Testing and Workload Limitations in Clinical Cytology 170-188
Böcking A, Adler CP, Common HH, Hilgarth M, Granzen B, Auffermann W (1984) Algorithm for a DNA-cytophotometric diagnosis and grading of malignancy. Anal Quant Cytol 6:1–8
Bullock GR, Petrusz P (Eds) (1985) Techniques in Immunocytochemistry, Vol 3, Academic Press, London, Orlando, San Diego, New York, Toronto, Montreal, Sydney, Tokyo
Burger G, Oberholzer M, Gössner W (Eds) (1988) Morphometrie in der Zytound Histopathologie. Springer-Verlag, Berlin, Heidelberg, New York, London, Paris, Tokyo
Chevalier J, Yi J, Michel O, Tang XM (1997) Biotin and digoxigenin as labels for light and electron microscopy in situ hybridization probes: where do we stand? J Histochem Cytochem 45:481–491
Cohen C (1996) Image cytometric analysis in pathology. Hum Pathol 27:482–493
Colvin RB, Bhan AK, McCluskey RT (Eds) Diagnostic immunopathology. 2nd Edn, Raven Press
Darzynkiewicz Z, Crissman HA (Eds) (1990) Flow cytometry. Academic Press Inc, San Diego, New York, Boston, London, Sydney, Tokyo, Toronto
Dauscher J, Hacker GW, Grimelius L, Nørgaard JOR (1993) Autometallographic silver amplification of colloidal gold. J Histotechnol 16:201–207
De Lellis RA (Ed) (1984) Advances in immunohistochemistry (Masson Monographs in Diagnostic Pathology). Masson Publ USA Inc, New York, Paris, Barcelona, Milan, Mexico City, Rio de Janeiro
Denk H (1987) Immunohistochemical methods for the demonstration of tumor markers. In: Morphological Tumor Markers (Current Topics in Pathology), G Seifert (Ed), pp 47–69. Springer, Berlin, Heidelberg, New York, London, Paris, Tokyo
Diest PJ van, Smeulders AWM, Thunissen FBJM, Baak JPA (1989) Cytomorphometry: A methodological study on preparation techniques, selection methods, and sample size. An Quant Cytol Histol 11:225–231
Fenoglio-Preiser CM, Willman CL (Eds) (1991) Molecular diagnostics in pathology. Williams and Wilkins, Baltimore, Hong-Kong, London, Sydney
Gown AM, Never N, Battifora H (1993) Microwave-based antigenic unmasking. A revolutionary new technique for routine immunohistochemistry. Applied Immunohistochem 1:256–266
Hames BD, Higgins SJ (Eds) (1990) Nucleic acid hybridization. A practical approach. IRL Press, Oxford, Washington
Hermsen MAJA, Meijer GA, Baak JPA, Joenje H, Walboo-mers JJM (1996) Comparative genomic hybridization: A new tool in cancer pathology. Hum Pathol 27:342–349
Herrington CS (1998) In situ hybridization. J Clin Pathol: Mol Pathol 51:8–13
Herrington CS, McGee JO’D (Eds) (1992) Diagnostic molecular pathology. A practical approach (Vol I and II). IRL Press, Oxford, New York, Tokyo
Hopman AHN, Claessen S, Speel EJM (1997) Multi-colour brightfield in situ hybridization on tissue sections. Histochem Cell Biol 108:291–298
Hsu SM, Raine L (1984) The use of avidin-biotin-peroxidase complex (ABC) in diagnostic and research pathology. In: Advances in Immunohistochemistry, RA De Lellis (Ed) pp 31–42. Masson Publ. USA, Inc., New York, Paris, Barcelona, Milan, Mexico City, Rio de Janeiro
Kallioniemi A, Kallioniemi OP, Sudar D, Rutovitz D, Gray JW, Waldman F, Pinkel D (1992) Comparative genomic hybridization for molecular cytogenetic analysis of solid tumors. Science 258:818–821
Komminoth P, Werner M (1997) Target and signal amplification approaches to increase the sensitivity of in situ hybridization. Histochem Cell Biol 108:325–333
Lan HY, Mu W, Nikolic-Paterson DJ, Atkins RC (1995) A novel, simple, reliable, and sensitive method for multiple immunoenzyme staining: use of microwave oven heating to block antibody crossreactivity and retrieve antigens. J Histochem Cytochem 43:97–102
Larsson LI (1993) Tissue preparation methods for light microscopic immunohistochemistry. Appl Immunohistochem 1:2–16
Long AA, Komminoth P (1997) In situ PCR. An overview. In: Methods in Molecular Biology, Vol 71: PRINS and In situ Protocols. Gosden JR, Ed; Humana Press Inc, Totowa, NJ
Longobardi Givan A (Ed) (1992) Flow cytometry. First principles. Wiley-Liss, New York, Chichester, Brisbane, Toronto, Singapore
McNicol AM, Farquharson MA (1997) In situ hybridization and its diagnostic applications in pathology. J Pathol 182:250–261
McNicol AM, Richmond JA (1998) Optimizing immunohistochemistry: Antigen retrieval and signal amplification. Histopathol 32:97–103
Melamed MR, Lindmo T, Mendelsohn ML (Eds) (1990) Flow cytometry and sorting (2nd Ed). Wiley-Liss, New York, Chichester, Brisbane, Toronto, Singapore
Mueller JD, Pütz B, Höfler H (1997) Self-sustained sequence replication (3SR): an alternative to PCR. Histochem Cell Biol 108:431–437
Nuovo GJ (1992) PCR in situ hybridization. Protocols and applications. Raven Press, New York
O’Leary JJ, Chetty R, Graham AK, McGee J O’D (1996) In situ PCR: pathologist’s dream or nightmare? J Pathol 178:11–20
Öfner D, Bankfalvi A, Riehemann K, Bier B, Böcker W, Schmid KW (1994) Wet autoclave pretreatment improves the visualization of silver-stained nuclear organizer region-associated proteins in routinely formalin-fixed and paraffin-embedded tissues. Modern Pathol 7:946–950
Öfner D, Bankfalvi A, Riehemann K, Böcker W, Schmid KW (1994) Standardisierte AgNOR-Färbemethode für for-malinfixiertes und paraffineingebettetes Material. Pathologe 15:226–230
Öfner D, Schmid KW (1996) Standardized AgNOR analysis: its usefulness in surgical oncology. Histochem Cell Biol 106:193–196
Ogawa K, Barka T (Eds) (1993) Electron microscopic cytochemistry and immunocytochemistry in biomedicine, CRC Press, Boca Raton, Ann Arbor, London, Tokyo
Petersen I, Schwendel A, Bockmühl U, Dietel M (1996) Die komparative genomische Hybridisierung. Pathologe 17:333–341
Piffko J, Bankfalvi A, Öfner P, Rasch D, Joos U, Schmid KW (1997) Standardized AgNOR analysis of the invasive tumour front in oral squamous cell carcinomas. J Pathol 182:450–456
Polak JM, McGee, JO’D (Eds) (1991) In situ hybridization. Principles and practice. Oxford University Press, Oxford, New York, Tokyo
Polak JM, Van Noorden S (Eds) (1986) Immunocytochemistry. Modern methods and applications, 2. Ed. John Wright & Sons Ltd, Bristol
Roth J (1984) Lightand electron-microscopic localization of antigens with the protein A-gold (pAg) technique. In: Advances in Immunohistochemistry, RA De Lellis (Ed) pp 43–65. Masson Publ. USA, Inc., New York, Paris, Barcelona, Milan, Mexico City, Rio de Janeiro
Rüschoff J (1992) Nukleolus organisierende Regionen (NORs) in der pathomorphologischen Tumordiagnostik (Veröffentlichungen aus der Pathologie). Gustav Fischer, Stuttgart, Jena, New York
Shi SR, Cote RJ, Taylor CR (1997) Antigen retrieval immunohistochemistry: past, present, and future. J Histochem Cytochem 45:327–343
Siebert R, Weber-Matthiesen K (1997) Fluorescence in situ hybridization as a diagnostic tool. Histochem Cell Biol 108:391–402
Smith MD, Triantapillon S, Parker A, Wikaningruin R, Coleman M (1997) A nonradioactive method of in situ hybridization that uses riboprobes and paraffin-embedded tissue and its combination with immunohistochemistry. Diagnostic Mol Pathol 6:34–41
Sternberger LA (1986) Immunocytochemistry, 3. Ed. John Wiley & Sons, New York, Chichester, Brisbane, Toronto
Taylor CR (1986) Immunomicroscopy: A diagnostic tool for the surgical pathologist. WB Saunders Comp, Philadelphia, London, Toronto, Mexico City, Rio de Janeiro, Sydney, Tokyo, Hong Kong
Taylor CR, Shi SR, Cote RJ (1996) Antigen retrieval for immunohistochemistry. Status and need for greater standardization. Appl Immunohistochem 4:144–166
Wanner I, Baader SL, Brich M, Oberdick J, Schilling K (1997) Subcellular localization of specific mRNAs and their protein products in Purkinje cells by combined fluorescence in situ hybridization and immunocytochemistry. Histochem Cell Biol 108:345–357
Wasielewsky R, Mengel M, Gignae S, Wilkens L, Werner M, Georgii A (1997) Tyramine amplification technique in routine immunohistochemistry. J Histochem Cytochem 45:1455–1459
Werner M, Wasielewski R, Komminoth P (1996) Antigen retrieval, signal amplification and intensification in immunohistochemistry. Histochem Cell Biol 105:253–260
Werner M, Wilkens L, Anbele M, Nolte M, Zitzelsberger H, Komminoth PC (1997) Interphase cytogenetics in pathology: principles, methods, and applications of fluorescence in situ hybridization (FISH). Histochem Cell Biol 108:381–390
Wiedmann M, Wilson WJ, Czajka J, Luo J, Barany F, Batt CA (1994) Ligase chain reaction (LCR) — overview and applications. In: PCR Methods and applications 3: S51–S64. Cold Spring Harbor Laboratory
Wilcox JN (1993) Fundamental principles of in situ hybridization. J Histochem Cytochem 41:1725–1733
Wilkens L, Tehinda J, Komminoth P (1997) Single-and double-color oligonucleotide primed in situ labeling (PRINS): applications in pathology. Histochem Cell Biol 108:439–446
Williams JH, Mepham BL, Wright DH (1997) Tissue preparation for immunocytochemistry. J Clin Pathol 50:422–428
Zitzelsberger H, Lehmann L, Werner M, Bauchinger M (1997) Comparative genomic hybridization for the analysis of chromosomal imbalances in solid tumors and haematological malignancies. Histochem Cell Biol 108:403–417
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Denk, H. (1999). Spezielle Untersuchungsmethoden in der diagnostischen Pathologie. In: Remmele, W. (eds) Pathologie. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-58620-0_4
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DOI: https://doi.org/10.1007/978-3-642-58620-0_4
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