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Avian Embryo as Model for Retinoid Function in Early Development

  • Chapter
Retinoids

Part of the book series: Handbook of Experimental Pharmacology ((HEP,volume 139))

Abstract

The importance of the micronutrient vitamin A throughout the life cycle has been well established in numerous studies (Moore 1957; Wolf 1984). It has more recently become quite clear that the requirement for vitamin A begins with embryonic life, and that retinoids, the vitamin A active forms that exert vitamin A function via their nuclear receptor, are critical signaling molecules during development, their absolute essentialness being best illustrated in the avian embryo model: vitamin A deficiency is embryolethal (DErsch and Zile 1993; Thompson 1969).

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Authors
  1. M. H. Zile
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Editors and Affiliations

  1. Department of Food Toxicology Center of Food Science, School of Veterinary Medicine, Bischofholer Damm, D-30173, Hannover, Germany

    Heinz Nau

  2. Department of Medicine Division of Preventive Medicine & Nutrition, College of Physicians and Surgeons of Columbia University, 630 West 168th Street, New York, NY, 10032, USA

    William S. Blaner Ph.D.

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© 1999 Springer-Verlag Berlin Heidelberg

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Zile, M.H. (1999). Avian Embryo as Model for Retinoid Function in Early Development. In: Nau, H., Blaner, W.S. (eds) Retinoids. Handbook of Experimental Pharmacology, vol 139. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-58483-1_15

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  • DOI: https://doi.org/10.1007/978-3-642-58483-1_15

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  • Print ISBN: 978-3-642-63614-1

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