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Transcriptional Regulation of the Desmin and SM22 Genes in Vascular Smooth Muscle Cells

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Book cover Tissue Repair and Fibrosis

Part of the book series: Current Topics in Pathology ((CT PATHOLOGY,volume 93))

Abstract

There are several stages in the differentiation of smooth-muscle cells (SMCs) (embryonic, fetal, prenatal and adult) and a number of genes are specifically activated at each stage. The factors regulating myogenesis in skeletal muscle responsible for determination and differentiation, members of the MyoD family, have been identified [23]. However, the transcriptional mechanisms regulating the various stages of determination and differentiation in vascular SMCs are still unknown. Our studies over the past few years have focused on the regulation of genes linked to the differentiation of this tissue.

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Authors
  1. M. Mericskay
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  2. Z. Li
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  3. D. Paulin
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Editor information

Editors and Affiliations

  1. GREF, Université Victor Segalen Bordeaux 2, 146, Rue Léo-Saignat, 33076, Bordeaux Cedex, France

    Alexis Desmoulière

  2. Départment de Nutrition, Université de Montréal, Pavillon Liliane-de-Stewart C. P. 6128, Succursale Centre-Ville, Montréal, Québec, H3C 3J7, Canada

    Beatriz Tuchweber

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© 1999 Springer-Verlag Berlin Heidelberg

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Mericskay, M., Li, Z., Paulin, D. (1999). Transcriptional Regulation of the Desmin and SM22 Genes in Vascular Smooth Muscle Cells. In: Desmoulière, A., Tuchweber, B. (eds) Tissue Repair and Fibrosis. Current Topics in Pathology, vol 93. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-58456-5_2

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  • DOI: https://doi.org/10.1007/978-3-642-58456-5_2

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-63603-5

  • Online ISBN: 978-3-642-58456-5

  • eBook Packages: Springer Book Archive

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