Skip to main content

Enzephalopathien bei erworbenen metabolischen Erkrankungen

  • Chapter

Zusammenfassung

Neurologische Symptome bei erworbenen metabolischen Störungen sind selten charakteristisch und setzen daher das Verständnis pathophysiologischer Zusammenhänge voraus. Die hypothesengesteuerte Differentialdiagnose und der gezielte Einsatz von apparativen Zusatzuntersuchungen sind besonders bei diesen kritisch kranken Patienten erforderlich. Nach Diagnosestellung zielt die Therapie weitgehend auf die Grunderkrankung. Um den Rahmen dieses Kapitels nicht zu sprengen, werden nur die wichtigsten erworbenen metabolischen Enzephalopathien und deren interdisziplinäres Management vorgestellt.

This is a preview of subscription content, log in via an institution.

Buying options

Chapter
USD   29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD   59.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD   79.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Learn about institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

Literatur

  • Adrogue H, Madias NE (1998) Management of life-threatening acid-base disorders. First of two parts. N Engl J Med 338:26–34.

    Article  CAS  PubMed  Google Scholar 

  • Adrogue H, Madias NE (1998) Management of life-threatening acid-base disorders. Second of two parts. N Engl J Med 338:107–111.

    Article  CAS  PubMed  Google Scholar 

  • Auer RN (1986) Progress review: Hypoglycémic brain damage. Stroke 17:699–708.

    Article  CAS  PubMed  Google Scholar 

  • Bilezikian JP (1989) Etiologies and therapy of hypercalcemia. Endocrinol Metab Clin North Am 18:389–414.

    CAS  PubMed  Google Scholar 

  • Bilezikian JP (1988) Hypercalcemia. Dis Mon 34:737–799.

    Article  CAS  PubMed  Google Scholar 

  • Bourke E, Delaney V (1993) Assessment of hypocalcemia and hypercalcemia. Clin Lab Med 13:157–181.

    CAS  PubMed  Google Scholar 

  • Butterworth RF (1996) The neurobiology of hepatic encephalopathy. Seminars in Liver Disease 3:235–244.

    Article  Google Scholar 

  • Calabresi P, Pisani A, Mercuri NB, Bernardi G (1995) On the mechanisms underlying hy-poxia-induced depolarization in striatal neurons. Brain 118:1027–1038.

    Article  PubMed  Google Scholar 

  • Cooper DJ, Walley KR, Wiggs BR (1990) Bicarbonat does not improve hemodynamics in critically ill patients who have lactic acidocis. Ann Intern Med 112:492–498.

    Article  CAS  PubMed  Google Scholar 

  • Della Porta P, Maiolo AT, Negri VU (1964) Cerebral blood flow and metabolism in therapeutic insulin coma. Metabolism 13:131–140.

    Article  Google Scholar 

  • Fraser CL, Arieff AI (1997) Epidemiology, Pathophysiology, and Management of Hyponatremic Encephalopathy. Am J Med 102:67–77.

    Article  CAS  PubMed  Google Scholar 

  • Fraser CL, Swanson RA (1994) Female sex hormones inhibit volume regulation in rat brain astrocyte culture. Am J Physiol (Cell Physiol 36) 267:C909–C914.

    CAS  Google Scholar 

  • Fujioka M, Okuchi K, Hiramatsu K, Sakaki T, Sakaguchi S, Ishii Y (1997) Specific changes in human brain after hypoglycémie injury. Stroke 28:584–587

    Article  CAS  PubMed  Google Scholar 

  • Herrera L, Kazemi H (1980) CSF bicarbonate regulation in metabolic acidosis: Role of HCO3 formation in CSF. J Appi Physiol 49:778–783.

    CAS  Google Scholar 

  • Hinchey J, Chaves C, Appignani B et al. (1996) A reversible posterior leukencephalopathy syndrome. N Engl J Med 334:494–500

    Article  CAS  PubMed  Google Scholar 

  • Iwai A, Sakamoto T, Kinoshita Y et al. (1987) Computed tomographic imaging of the brain after hypoglycémie coma. Neuroradiology 29:398–400.

    Article  CAS  PubMed  Google Scholar 

  • Johansson BB (1983) The blood-brain barrier and cerebral blood flow in acute hypertension. Acta Med Scand Suppl 678:107–112.

    CAS  PubMed  Google Scholar 

  • Kitabchi AE, Murphy MB (1988) Diabetic ketoacidosis and hyperosmolar hyperglycémic non-ketotic coma. Med Clin N Am 72:1545–1560.

    Article  CAS  PubMed  Google Scholar 

  • Krieger D, Krieger S, Jansen O et al. (1995) Manganese and chronic hepatic encephalopathy. Lancet 346:270–274.

    Article  CAS  PubMed  Google Scholar 

  • Krieger S, Jauß M, Jansen O, Theilmann L, Geißler M, Krieger D (1996) Neuropsychiatrie profile and hyperintense globus pallidus on T1-weighted magnetic resonance images in liver cirrhosis. Gastroenterology 111:147–155.

    Article  CAS  PubMed  Google Scholar 

  • Lassen NA (1974) Control of cerebral circulation in health and disease. Circ Res 34:79–760.

    Article  Google Scholar 

  • Lee JH, Arcinue E, Ross BD (1994) Brief report: organic osmolytes in the brain of an infant with Hypernatremia. N Engl J Med 331:439–442.

    Article  CAS  PubMed  Google Scholar 

  • McManus ML, Churchwell KB, Strange K (1995) Regulation of cell volume in health and disease. N Engl J Med 333:1260–1266.

    Article  CAS  PubMed  Google Scholar 

  • Miller AL (1985) Carbon dioxide narcosis. In: McCandless DW (ed) Cerebral energy metabolism and metabolic encephalopathy. Plenum Press, New York, pp 143–162.

    Chapter  Google Scholar 

  • Mundy GR (1990) Incidence and pathophysiology of hypercalcemia. Calcif Tissue Int 46 (Suppl):3–10.

    Article  Google Scholar 

  • Norenberg MD (1983) A hypothesis of osmotic endothelial injury. Arch Neurol 40:66–69.

    Article  CAS  PubMed  Google Scholar 

  • Ohlinger ML (1989) Disorders of calcium and magnesium metabolism. Emerg Med Clin North Am 7:795–822.

    Google Scholar 

  • O’Grady JG, Alexander GJM, Hayllar KM, Williams R (1989) Early indicators of prognosis in fulminant hepatic failure. Gastroenterology 97:439–445.

    Article  PubMed  Google Scholar 

  • Patten BM, Bilezikian JP, Mallette LE (1974) Neuromuscular disease in primary hyperpara-thyroidism. Ann Int Med 80:182–193.

    Article  CAS  PubMed  Google Scholar 

  • Riordan SM, Williams R (1997) Treatment of hepatic encephalopathy. N Engl J Med 337:473–479.

    Article  CAS  PubMed  Google Scholar 

  • Tien R, Arieff AI, Kucharczyk W et al. (1992) Hyponatremic encephalopathy: Is central pontine myelinolysis a component? Am J Med 92:513–522.

    Article  CAS  PubMed  Google Scholar 

  • Wijdicks EFM, Plevak DJ, Rakela J, Wiesner RH (1995) Clinical and radiologic features of cerebral edema in fulminant hepatic failure. Mayo Clin Proc 70:119–124.

    Article  CAS  PubMed  Google Scholar 

  • Zaloga GP (1992) Hypocalcemia in critical ill patients. Crit Care Med 20:251–262.

    Article  CAS  PubMed  Google Scholar 

Download references

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 1999 Springer-Verlag Berlin Heidelberg

About this chapter

Cite this chapter

Krieger, S., Petros, S., Berrouschot, J., Krieger, D. (1999). Enzephalopathien bei erworbenen metabolischen Erkrankungen. In: Schwab, S., Krieger, D., Müllges, W., Hamann, G., Hacke, W. (eds) Neurologische Intensivmedizin. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-58415-2_31

Download citation

  • DOI: https://doi.org/10.1007/978-3-642-58415-2_31

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-63583-0

  • Online ISBN: 978-3-642-58415-2

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics