Die akute Subarachnoidalblutung

  • H. H. Steiner
  • A. Unterberg


Trotz zunehmender Kenntnisse über die pathophysiologischen Grundlagen der akuten Subarachnoidalblutung, der Einführung mikrochirurgischer sowie interventionell-neuroradiologischer Behandlungsmethoden und der Verbesserung in der anästhesiologisch-intensivmedizinischen Versorgung ist die Prognose der Erkrankung mit einer nach wie vor erheblichen Letalität und Mor-bidität verknüpft.


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  1. 1.
    Ahmad I, Imaizumi S, Shimizu H et al. (1996) Development of Calcitonin Gene-Related Peptide Slow-Release Tablet implanted in CSF Space for Prevention of cerebral vaso-spasm after experimental subarachnoid hemorrhage. Acta Neurochir 138:1230–1240.CrossRefPubMedGoogle Scholar
  2. 2.
    Asari S, Ohmoto T (1993) Natural history and risk factors of unruptured cerebral an-eurysms. Clin Neurol Neurosurg 95:205–214.CrossRefPubMedGoogle Scholar
  3. 3.
    Bailes JE, Spetzler RF, Hadley MN, Baldwin HZ (1990) Management morbidity and mortality of poor-grade aneurysm patients. J Neurosurg 72:559–566.CrossRefPubMedGoogle Scholar
  4. 4.
    Barker FG, Ogilvy S (1996) Efficacy of prophylactic Nimodipine for delayed ischemic deficit after subarachnoid hemorrhage: A metaanalysis. J Neurosurg 84:405–414.CrossRefPubMedGoogle Scholar
  5. 5.
    Clyde BL, Resnick DK, Yonas H (1996) The relationship of blood vessel velocity as measured by transcranial doppler ultrasonography to cerebral blood flow as determined by stable xenon computed tomographic studies after aneurysmal subarachnoid hemorrhage. Neurosurgery 38:896–905.CrossRefPubMedGoogle Scholar
  6. 6.
    Elliott JP, Newell DW, Can DJ, Win HR et al. (1998) Comparison of ballon angioplasty and papaverin infusion for the treatment of vasospasm following aneurysmal subarachnoid hemorrhage. J Neurosurg 88:277–284.CrossRefPubMedGoogle Scholar
  7. 7.
    Hund E, Aschoff A, Tronnier V, Hampl J, Kunze ST (1990) Nimodipine: Evidence for clinically significant gastrointestinal side-effects. Acta Neurochir 102:73–75.CrossRefPubMedGoogle Scholar
  8. 8.
    Huetter BO, Gilsbach JM, Kreitschmann I (1995) Qualitiy of life and cognitive deficits after subarachnoid hemorrhage. Brit J Neurosurg 9:465–475.CrossRefGoogle Scholar
  9. 9.
    Hunt WE, Hess RM (1968) Surgical risk as related to time of intervention in the repair of intracranial aneurysms. J Neurosurg 28:14–20.CrossRefPubMedGoogle Scholar
  10. 10.
    Kassell NF, Haley EC Jr, Apperson-Hansen C, Alves WM (1996) Randomized, double-blind, vehicle-controlled trial of Tirilazad mesylate in patients with aneurysmal subarachnoid hemorhage: A cooperative study in Europe, Australia, and New Zealand. J Neurosurg 84:221–228.CrossRefPubMedGoogle Scholar
  11. 11.
    Kassell NF, Torner JC, Haley EC et al. (1990) The international cooperative study on the timing of aneurysm surgery, part 1 and part 2. J Neurosurg 73:18–47.CrossRefPubMedGoogle Scholar
  12. 12.
    Lawton MT, Daspit CP, Spetzler RF (1997) Technical aspects and recent trends in the management of large and giant midbasilar artery aneurysms. Neurosurgery 41:513–520.PubMedGoogle Scholar
  13. 13.
    Malisch TW, Guglielmi G, Vinuela F et al. (1997) Intracranial aneurysms treated with the Guglielmi detachable coil: Midterm clinical results in a consecutive series of 100 patients. J Neurosurg 87:176–183.CrossRefPubMedGoogle Scholar
  14. 14.
    Murayama Y, Malisch T, Guglielmi G et al. (1997) Incidence of cerebral vasospasm after endovascular treatment of acutely ruptured aneurysms: Report on 69 cases. J Neurosurg 87:830–835.CrossRefPubMedGoogle Scholar
  15. 15.
    Persson L, Valtysson J, Enblad P et al. (1996) Neurochemical monitoring using intra-cerebral microdialysis in patients with subarachnoid hemorrhage. J Neurosurg 84:606–618.CrossRefPubMedGoogle Scholar
  16. 16.
    Poeck K, Hacke W (1998) Neurologie, 10. Auf. Springer, Berlin Heidelberg New York Tokyo.CrossRefGoogle Scholar
  17. 17.
    Polin RS, Hansen CA, German P, Shadduck JB, Kassell NF, Study Participants (1998) Intra-arterialy administered papaverine for the treatment of symptomatic cerebral va-sospasm. Neurosurgery 42:1256–1264.CrossRefPubMedGoogle Scholar
  18. 18.
    Schneider GH, Unterberg A, Lanksch WR (1996) Hypervolemic — hypertensive hemodi-lution for treatment of delayed ischemic deficits following subarachnoid hemorrhage. Zentralbl Neurochir [Suppl l]:67–68.Google Scholar
  19. 19.
    Seifert V, Loeffler BM, Zimmermann M, Roux S, Stolke D (1995) Endothelin concentrations in patients with aneurysmal subarachnoid hemorrhage. J Neurosurg 82:55–61.CrossRefPubMedGoogle Scholar
  20. 20.
    Standard SC, Guterman LR, Chavis TD et al. (1994) Endovascular management of giant intracranial aneurysms. In: Clinical neurosurgery. Williams & Wilkins, Baltimore, pp 267–293.Google Scholar
  21. 21.
    Steiner HH, Kremer P, Kunze S (1994) Die akute Subarachnoidalblutung nach Aneurys-maruptur: Ergebnisse der Frühoperation. Zentralbl Neurochir 55:16–23.PubMedGoogle Scholar

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© Springer-Verlag Berlin Heidelberg 1999

Authors and Affiliations

  • H. H. Steiner
  • A. Unterberg

There are no affiliations available

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