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Heat Shock Proteins in Atherosclerosis

  • Chapter
Stress Proteins

Part of the book series: Handbook of Experimental Pharmacology ((HEP,volume 136))

Abstract

Atherosclerosis is a progressive pathological lesion of the arterial wall, arising as a consequence of chronic vascular injury. This review will briefly describe changes in heat shock protein (Hsp) distribution and expression levels that have been observed during atherosclerotic plaque evolution, then examine evidence that altered Hsp production and distribution within the arterial wall directly contributes to lesion formation and progression. Throughout the review, and in closing, some currently unanswered questions needing further investigation also will be outlined.

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Authors
  1. A. D. Johnson
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Editors and Affiliations

  1. Department of Molecular Pathology, University College London, Cleveland Street, London, W1P 6DB, UK

    David S. Latchman M.A. Ph.D., D.Sc. (Head, Director) (Head, Director)

  2. Windeyer Institute of Medical Sciences, University College London, Cleveland Street, London, W1P 6DB, UK

    David S. Latchman M.A. Ph.D., D.Sc. (Head, Director) (Head, Director)

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© 1999 Springer-Verlag Berlin Heidelberg

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Johnson, A.D. (1999). Heat Shock Proteins in Atherosclerosis. In: Latchman, D.S. (eds) Stress Proteins. Handbook of Experimental Pharmacology, vol 136. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-58259-2_18

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  • DOI: https://doi.org/10.1007/978-3-642-58259-2_18

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-63519-9

  • Online ISBN: 978-3-642-58259-2

  • eBook Packages: Springer Book Archive

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