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Neuroendocrine-Renal Relationships in Heart Failure: Effect of Captopril

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Heart Failure Mechanisms and Management

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Abstract

The haemodynamic effects of angiotensin converting enzyme (ACE) inhibitors have been extensively examined in patients with chronic heart failure. The renal effects of these drugs have, however, been less well studied [1]. The relatively few studies that have evaluated the renal actions of ACE inhibitors in chronic heart failure have shown an acute fall in urinary sodium excretion [2–4]. The present study was designed to investigate the mechanism, or mechanisms, of this early sodium-retaining effect of ACE inhibitors.

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Authors
  1. J. McMurray
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  2. J. McLay
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  3. A. D. Struthers
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Editor information

Editors and Affiliations

  1. Department of Cardiology, Lady Davis Carmel Hospital, 34362, Haifa, Israel

    Basil S. Lewis MD (Director) (Director)

  2. University of California, Los Angeles, USA

    Asher Kimchi MD (Assistant Clinical Professor of Medicine, Attending Physician) (Assistant Clinical Professor of Medicine, Attending Physician)

  3. Division of Cardiology, Cedars-Sinai Medical Center, Los Angeles, CA, 90048, USA

    Asher Kimchi MD (Assistant Clinical Professor of Medicine, Attending Physician) (Assistant Clinical Professor of Medicine, Attending Physician)

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© 1991 Springer-Verlag Berlin Heidelberg

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McMurray, J., McLay, J., Struthers, A.D. (1991). Neuroendocrine-Renal Relationships in Heart Failure: Effect of Captopril. In: Lewis, B.S., Kimchi, A. (eds) Heart Failure Mechanisms and Management. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-58231-8_24

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  • DOI: https://doi.org/10.1007/978-3-642-58231-8_24

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-63509-0

  • Online ISBN: 978-3-642-58231-8

  • eBook Packages: Springer Book Archive

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