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Hagers Handbuch der Pharmazeutischen Praxis

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Literatur

  1. Fujii S, Watanabe T (1971) Ger Offen 2,050,484; 22.April 1971, Japan Appl 14.October 1969, zit. nach CA (1971)75:6324d

    Google Scholar 

  2. Unno K, Suzuki T, Ataku K, Nakata H, Tornino A (1979) Heterocycles 12:801–810

    Article  CAS  Google Scholar 

  3. Fukuchi H, Yoshida M, Tsukiai S, Kumagai M, Kitaura T, Shintani H, Kuwada N, Konishi T (1985) Pharm Ind 47: 657–660

    CAS  Google Scholar 

  4. Menegatti E, Scalia S, Bortolotti F, Ascenzi P, De Marco A, Guarneri M (1985) Pharm Acta Helv 60:170– 174

    Google Scholar 

  5. Shibata K, Sekizuka M, Kumakawa Y, Maki Y (1989) Byoin Yakugaku 15: 248–254

    CAS  Google Scholar 

  6. Weinmann HJ, Brasch RC, Press WR, Wesby GE (1984) Am J Roentgenol 142:619; Pat. US 46 47 447 A 3. Mär. 1987, zit. nach CA 107:112217k; Can 1240679 A2 16 Aug. 1988, zit. nach CA 112: 73025c

    CAS  Google Scholar 

  7. Bligh SWA, Drake AF, Sadler PJ (1989) Eur J Biochem (1989) 181:223–224, zit. nach CA 110:219058y

    Google Scholar 

  8. Brown MA, Stenzel TT, Ribiero AA, Drayler BP (1986) Magn Reson Med 3:289–295, zit. nach CA 105: 93924d

    Google Scholar 

  9. Vora MM, Wukovnig S, Finn RD, Emran AM, Boothe TE, Kothari PJ (1986) J Chromatogr 369: 187–192

    Article  CAS  Google Scholar 

  10. Gries H, Miklautz H (1984) Physiol Chem Phys Med NMR 16:105–112, zit. nach CA 102: 12266d

    Google Scholar 

  11. Schörner W (1988) Kontrastmittel in der Kernspintomographie, Medizinisch-wissenschaftliche Buchreihe der Schering Aktiengesellschaft

    Google Scholar 

  12. Niendorf HP, Semmler W, Laniado M, Felix R (1986) Diagn Imag Clin Med 55: 25–36

    CAS  Google Scholar 

  13. Brasch RC (1983) Radiology 147: 781–788

    PubMed  CAS  Google Scholar 

  14. Runge VM, Claton JA, Lukehart CM, Partain CL, James AE (1983) Amer J Roentgenol 141: 1209–1215

    CAS  Google Scholar 

  15. Weinmann HJ, Brasch RC, Press WR, Wesbey GE (1984) Amer J Roentgenol 142: 619–624

    CAS  Google Scholar 

  16. Felix R, Schörner W, Sander B, Henkes H, Bittner R (1988) Diagn Imaging 4: 13–15

    Google Scholar 

  17. Russel EJ, Schaible TF, Dillon W, Drayer B, Li Puma J, Mancuso A, Maravilla K, Goldstein HA (1989) AJR 152: 813–823

    Google Scholar 

  18. Jenkins JPR, Gholkar A, Antoun NM, Stack JP, Isherwood I (1988) Diagn Imaging 4: 24–25

    Google Scholar 

  19. Weinmann HJ (1986) In: Runge VMC, Claussen C, Felix R, James AE (Eds.) Contrast agents in magnetic resonance imaging, Excerpta medica, Amsterdam Hong Kong Princeton Sydney Tokyo, p. 19–23

    Google Scholar 

  20. Niendorf HP (1988) Diagn Imaging 4: 16–17

    Google Scholar 

  21. Yakovleva AP (1963) Zh Obshch Khim 33(5):1691–1693, zit. nach CA (1963) 59: 13144h

    Google Scholar 

  22. Bubeva-Ivanova L, Ivanov V (1961) Tr Nauchno Izsled Inst Farm 3:70–75, zit. nach CA (1964) 61: 14465h

    Google Scholar 

  23. Barton DHR, Kirby GW (1962) J Chem Soc 806–817

    Google Scholar 

  24. Abdallah OM, Ali AA, Itokawa H (1989) Phytochemistry 28 (11): 3248–3249

    Article  CAS  Google Scholar 

  25. Kobayashi S et al. (1985) Chem Pharm Bull 33 (12): 5258–5263

    Article  CAS  Google Scholar 

  26. Boit HG, Ehmke H (1955) Chem Ber 88 (10): 1590–1594

    Article  CAS  Google Scholar 

  27. Ghosal S, Shanty A, Singh SK (1988) Phytochemistry 27 (6): 1849–1852

    Article  CAS  Google Scholar 

  28. Kobayashi S et al. (1976) Chem Pharm Bull 24(7)1537–1543

    Article  CAS  Google Scholar 

  29. Batisda J et al. (1987) Phytochemistry 26: 1519–1524

    Article  Google Scholar 

  30. Wildman WC (1960) in The Alkaloids (Manske, Hrsg.) 6:291 (Pergamon-Press, London, New York )

    Google Scholar 

  31. Tanahashi T, Poulev A, Zenk MH (1990) Planta Med 56: 77–81

    Article  PubMed  CAS  Google Scholar 

  32. Uyeo S, Kobayashi S (1953) Pharm Bull (Tokyo) 1:139, zit. in 10.

    Article  CAS  Google Scholar 

  33. Proskurnina NF, Yakovleva AD (1952) Zhur Obshchei Khim 22:1899, zit. in 10.

    CAS  Google Scholar 

  34. Döpke W (1962) Archiv der Pharmazie 295 (8): 605–606

    Article  Google Scholar 

  35. DAB 10

    Google Scholar 

  36. Bjoernstad T, Holtebekk T (1983) Rep. Ser. 83-01; zit. nach CA 99:78613r; Bern D, Burjan V, Schaferlingsva W, Vincour J (1977) Report; zit. nach CA 89: 152688f

    Google Scholar 

  37. Bjoernstad T, Holtebeck T (1983) Rep Ser 83-01, zit. nach CA 99: 78613r

    Google Scholar 

  38. Knoll AG Chemische Fabriken (1962) Belg 615861, zit. nach CA 59: 13892g

    Google Scholar 

  39. Dibbern HW (1991) UV- und IR-Spektren wichtiger pharmazeutischer Wirkstoffe, Editio Cantor, Aulendorf Frankfurt/Main, S. 1. 447

    Google Scholar 

  40. Kle82

    Google Scholar 

  41. Kaltenbach M, Lichtlen PR (Hrsg.) (1989) Z Kardiol 78 (Suppl 5): 1–120

    Google Scholar 

  42. Bender F, Meesmann W (Hrsg.) (1987) Therapie mit Gallopamil: Neue Forschungsergebnisse zum Kalziumantagonismus, Steinkopff, Darmstadt

    Google Scholar 

  43. Nayler W (1990) Calcium-Antagonisten, Springer, Berlin Heidelberg New York

    Book  Google Scholar 

  44. Nayler W (1992) Second generation of calcium antagonists, Springer-Verlag, Berlin-Heidelberg-New York

    Google Scholar 

  45. Lydtin H, Trenkwalder P (1988) Calcium-Antagonisten: Eine kritische Analyse, Springer, Berlin Heidelberg New York

    Google Scholar 

  46. Wolf E (1987) Therapiewoche 37:2. 372–2. 380

    Google Scholar 

  47. Dibbern HW (1978) UV- und IR-Spektren wichtiger pharmazeutischer Wirkstoffe, Editio Cantor, Aulendorf

    Google Scholar 

  48. Angaben der Firma Rhône-Poulenc Rorer, Köln

    Google Scholar 

  49. Helwig H, Otto HH (1990) Arzneimittel, 7. Aufl., Wissenschaftliche Verlagsgesellschaft, Stuttgart

    Google Scholar 

  50. DAB10, Monographie Verapamilhydrochlorid

    Google Scholar 

  51. WO 9011283 AI 04.10.1990; zit. nach CA 114(23):229304x

    Google Scholar 

  52. Boerge A, Clausen FP, Juhl-Christensen J, McCluskey KK, Preikschat HF (1991) J Org Chem 56:(6) 2.139–2.143; zit. nach CA 114(15):142963n

    Google Scholar 

  53. McGee DPC, Martin JC, Verheyden JPH (1988) Synth Commun 18:(14)1.651–1.660; zit. nach CA 110 (17):154776j

    Google Scholar 

  54. ES 549248 AI 01.04.1986; zit. nach CA 107(15):134629y

    Google Scholar 

  55. AT 382152 B 26.01.1987; zit. nach CA 107(11):96732s

    Google Scholar 

  56. Ogilvie KK, Hanna HR, Proba Z (1986) Nucleosides Nucleotides 5:(2)169–183; zit. nach CA 106(25):214258w

    Google Scholar 

  57. US 4642346 A 10.02.1987; zit nach CA 106(16):125879g

    Google Scholar 

  58. ES 548093 AI 01.02.1986; zit. nach CA 106(9):67007h

    Google Scholar 

  59. EP 165164 AI 18.12.1985; zit. nach CA 105(7):60479j

    Google Scholar 

  60. McGee DPC, Martin JC, Verheyden JPH (1985) J Heterocycl Chem 22:(4) 1. 137–1. 140

    Google Scholar 

  61. EP 152965 A2 28.08.1985; zit. nach CA 104(13):109361k

    Google Scholar 

  62. US 4508898 A 02.04.1985; zit nach CA 103(9):71626q

    Google Scholar 

  63. Visor GC, Jackson SE, Kenley RA, Lee GC (1985) J Pharm Sci 74:(10) 1.078–1.081; zit. nach CA 103(26):220907m

    Google Scholar 

  64. Visor GC, Jackson SE, Kenley RA, Lee GC (1985) J Liq Chromatogr 8:(8) 1.475–1.488; zit. nach CA 103(14):110023n

    Google Scholar 

  65. Hedaya MA, Sawchuk RJ (1990) Pharm Res 7:1. 113–1. 118

    Google Scholar 

  66. Firmenangabe (Syntex)

    Google Scholar 

  67. Freitas V, Smee DF, Chernow M, Boehme R, Matthews TR (1985) Antimicrob Agents Chemother 28: 240–245

    Article  PubMed  CAS  Google Scholar 

  68. Matthews T, Boehme R (1988) Rev Inf Dis 10 (Suppl 3): S490–S494

    Article  CAS  Google Scholar 

  69. Smee DF, Martin JC, Verheyden JPH, Matthews TR (1983) Antimicrob Agents Chemother 23: 676–682

    Article  PubMed  CAS  Google Scholar 

  70. Cheng YC, Huang ES, Lin JC, Mar EC, Pagano JS, Dutschman GE, Grill SP (1983) Proc Nat Acad Sci USA 80:2. 767–2. 770

    Google Scholar 

  71. Field AK, Davies ME, Dewitt C, Perry HC, Liou R, Germershausen J, Karkas JD, Ashton WT, Johnston DBR, Tolman RL (1983) Proc Nat Acad Sci USA 80:4. 139–4. 143

    Google Scholar 

  72. Manischewitz JF, Quinnan GV, Lane HC, Wittek AE (1990) Antimicrob Agents Chemother 34: 373–375

    Article  PubMed  CAS  Google Scholar 

  73. Erice A, Chou S, Biron KK, Stanat SC, Balfour HH jr, Jordan MC (1989) New Engl J Med 320: 289–293

    Article  PubMed  CAS  Google Scholar 

  74. Jacobsen MA, De Miranda P, Cederberg DM, Burnette T, Cobb E, Brodie HR, Mills J (1987) Antimicrob Agents Chemother 31:1. 251–1. 254

    Google Scholar 

  75. NN (1988) Information des Herstellers. Syntex Arzneimittel, 5100 Aachen, 1989

    Google Scholar 

  76. Douglas RG jr (1990) Ganciclovir. In: Goodman S, Gilman A, Rall TW, Nies AS, Taylor P (Hrsg.) The pharmacological basis of therapeutics, The Pergamon Press, New York, S 1.186–1. 187

    Google Scholar 

  77. Sommadossi JP, Bevan R, Ling T, Lee F, Mastre B, Chaplin MD, Nerenberg C, Koretz S, Buhles WC (1988) Rev Inf Dis 10 (Suppl 3): S507–S514

    Article  Google Scholar 

  78. Rubin RH (1990) Rev Inf Dis 12 (Suppl 7): S691–S860

    Article  Google Scholar 

  79. Laskin OL, Cederberg DM, Mills J, Eron LJ, Mildvan D, Spector SA (1987) Am J Med 83: 201–206

    Article  PubMed  CAS  Google Scholar 

  80. Chahoua A, Dieterich D, Krasinski K, Greene J, Laubenstein L, Wernz J, Buhles WC, Koretz S (1987) Ann Int Med 107: 133–137

    Google Scholar 

  81. Hochster H, Dieterich D, Bozzette S, Reichman RC, Connor JD, Liebes L, Sonke RL, Spector SA, Valentine F, Pettinelli C, Richman DD (1990) Ann Int Med 113: 111–117

    PubMed  CAS  Google Scholar 

  82. Corey EJ, Sehaaf TK, Huber W, Weinshenker NM (1970) J Am Chem Soc 92: 397–398

    Article  PubMed  CAS  Google Scholar 

  83. House HO, Jones VK, Frank GA (1964) J Org Chem 29: 3327–3333

    Article  CAS  Google Scholar 

  84. Suga H, Konishi Y, Wakatsuka H, Miyake H, Kori S, Hayashi M (1978) Prostaglandins 15: 907–912

    Article  PubMed  CAS  Google Scholar 

  85. Dimoy V, Green K, Bydgeman M, Konishi Y, Imaki K, Hayashi M (1983) Prostaglandins 25: 225–235

    Article  Google Scholar 

  86. Hansch C, Sammes PG, Taylor JB (Hrsg.) (1990) Comprehensive Medicinal Chemistry, Pergamon Press, Oxford Bd. 6, S. 555

    Google Scholar 

  87. Zagermann P, Liekfeld H, Morck H, Schneider L, Schulz M, Thesen R (1990) Pharm Ztg 14: 40–12

    Google Scholar 

  88. Rath W, Adelmann-Grill BC, Schauer A, Kuhn W (1988) Physikalische, morphologische und biochemische Untersuchungen zur Prostaglandin-induzierten Cervixreifung im 1. Trimenon. In: Haller U, Kubli F, Husslein P (Hrsg.) Prostaglandine in Geburtshilfe und Gynäkologie, Springer, Berlin Heidelberg New York London Paris Tokyo, S. 58–70

    Chapter  Google Scholar 

  89. Standardinformation für Krankenhausapotheker: Cergem Vaginalzäpfchen (1990) Nourypharma

    Google Scholar 

  90. Cergem Firmenbroschüre (1989) Nourypharma

    Google Scholar 

  91. Rabe T, Willinger G, Kiesel B, Runnebaum B, Kubli F, Mösche R, Nobakh N (1985) Adv Contracept 1: 91–102

    Article  PubMed  CAS  Google Scholar 

  92. Lawrence AS, Healy DL, Hill D, Paterson PJ (1991) Med J Aust 154: 280–282

    PubMed  CAS  Google Scholar 

  93. Mar 29, S. 1.373

    Google Scholar 

  94. DE 1925423 (1969), zit. nach CA (1970) 72:43167

    Google Scholar 

  95. Dibbern HW (Hrsg.) (1978) UV- und IR-Spektren wichtiger pharmazeutischer Wirkstoffe, Edition Cantor Aulendorf, S. 1812

    Google Scholar 

  96. Hansch C, Sammes PG, Taylor JB (Hrsg.) (1990), Comprehensive Medicinal Chemistry, Pergamon Press Oxford, Bd. 6, S. 555

    Google Scholar 

  97. Haky JE, Lejy B, Schneider HG (1983) J Chromatogr 264: 287–290

    Article  CAS  Google Scholar 

  98. Randinitis EJ, Parker III TD, Kinkel AW (1986) J Chromatogr 383: 444–448

    Article  PubMed  CAS  Google Scholar 

  99. Cayen MN (1985) Pharmacol Ther 29: 157–204

    Article  PubMed  CAS  Google Scholar 

  100. Manninen V (1983) Am J Cardiol 52: 35B–38B

    Article  PubMed  CAS  Google Scholar 

  101. Todd PA, Ward A (1988) Drugs 36: 314–339

    Article  PubMed  CAS  Google Scholar 

  102. Manttari M, Koskinen P, Manninen V, Huttunen JK, Frick MH, Nikkila EA (1990) Atherosclerosis 81: 11–17

    Article  PubMed  CAS  Google Scholar 

  103. Glueck C (1983) Am J Cardiol 52: 31B–34B

    Article  PubMed  CAS  Google Scholar 

  104. Leaf DA, Connor WE, Illingworth DR, Bacon SP, Sexton G (1989) J Am Med Assoc 262:3. 154–3. 160

    Google Scholar 

  105. Newton RS (1990) Pharmacological activity of lipid regulating agents on plasma triglyceride and high density lipoprotein levels. In: Lenfant D (Hrsg.) Biotechnology of dyslipoproteinemias applications in diagnostics and control, Raven Press, New York, S. 119–125

    Google Scholar 

  106. Nikkila EA, Ylikahri OR, Huttunen JK (1976) Proc Roy Soc Med 69 (Suppl 2): 58–63

    PubMed  Google Scholar 

  107. Vessby G, Lithell H, Boberg J, Hellsing K, Werner I (1976) Proc Roy Soc Med 69 (Suppl 2): 32–37

    PubMed  Google Scholar 

  108. Rasi VPO, Torstila I (1976) Proc Roy Soc Med 69 (Suppl 2): 64–70

    Google Scholar 

  109. Laustiola K, Lassila R, Koskinen P, Pellinen T, Manninen V (1988) Clin Pharmacol Ther 43: 302–307

    Article  PubMed  CAS  Google Scholar 

  110. Bertolini S, Cordera R, Marcenaro A (1990) Diabetes Nutr Metab 3: 23–34

    Google Scholar 

  111. Frick MH, Elo O, Haapa K, Heinonen OP, Heinsalmi P, Helo P, Huttunen JK, Kaitaniemi P, Koskinen P, Manninen V, Mäenpää H, Mälkönen M, Mänttäri M, Norola S, Pasternack A, Pikkarainen J, Romo M, Sjöblom T, Nikkila EA (1987) N Engl J Med 317:1. 237–1. 245

    Google Scholar 

  112. Thelle DS (1990) Drug Invest 2 (Suppl 2): 1–8

    Article  Google Scholar 

  113. LaRosa JC (1990) Am J Cardiol 65: 7F–10F

    Article  PubMed  CAS  Google Scholar 

  114. Olsson AG, Rössner S, Walldius G, Carlson LA (1976) Proc Roy Soc Med 69 (Suppl 2): 28–31

    PubMed  CAS  Google Scholar 

  115. Manninen V, Malkönen M, Eisalo A, Virtamo J, Tuomilehto J, Kuusisto P (1982) Acta Med Scand 68 (Suppl): 82–87

    Google Scholar 

  116. Adam D, Christ W (1987) In: Forth W, Henschler D, Rummel W (Hrsg.) Antibiotika und Chemotherapeutika, Wissenschaftsverlag, Mannheim Zürich Wien, S. 625–632

    Google Scholar 

  117. Drews J (1979) Grundlagen der Chemotherapie, Springer, Wien New York, S. 155–158

    Book  Google Scholar 

  118. Walther H, Meyer FP (1987) Klinische Pharmakologie antibakterieller Arzneimittel, Urban & Schwarzenberg, München Wien Baltimore, S. 277–310

    Google Scholar 

  119. Simon C, Stille W (1985) Antibiotika-Therapie in Klinik und Praxis, Schattauer, Stuttgart New York, S. 153–159

    Google Scholar 

  120. Tauchnitz C, Handrick W (1989) Rationale antimikrobielle Chemotherapie, Barth, Leipzig, S. 123–126

    Google Scholar 

  121. Tschäpe H, Witte W, Rische H (1983) Dtsch Gesundheitswes 38: 845–853

    Google Scholar 

  122. Witte W, Klare I, Halle E, Spencker FB, Böhme G (1990) Z Klin Med 45:1. 389–1. 393

    Google Scholar 

  123. Kelman AW, Thomson AH, Whitting B, Bryson SM, Steedman DA, Mawer GE, Samba-Donga LA (1984) Br J Clin Pharmacol 18: 685–692

    Article  PubMed  CAS  Google Scholar 

  124. Keller F (1989) Br J Clin Pharmacol 28: 479–481

    Article  PubMed  CAS  Google Scholar 

  125. Miranda JC, Schimmel MM, James LS, Spinelli W, Rosen TS (1985) Pediat Pharmacol 5: 57–61

    CAS  Google Scholar 

  126. Kasik JW, Jenkins S, Leuschen MP, Nelson MD (1985) J Pediat 106: 502–505

    Article  PubMed  CAS  Google Scholar 

  127. Gonzáles-Martin G, Bravo I, Vargas H, Arancibia A (1986) Int J Clin Pharmacol Ther Tox 24: 555–558

    Google Scholar 

  128. Van Rens JG, Kayser FH (Hrsg.) (1981) Local antibiotic treatment in osteomyelitis and soft-tissue infections. Proc of a Symposium, Amsterdam 1980, Excerpta Medica. International Congress Series 556, Amsterdam Oxford Princeton

    Google Scholar 

  129. Wahlig H (1986) Die Geschichte der Biomaterialien als Wirkstoffträger, Medizinisch Pharmazeutische Studiengesellschaft, Mainz

    Google Scholar 

  130. Rameis H, Hitzenberger G, Jaschke I, Graninger W (1980) Dtsch Med Wochenschr 105:1. 650–1. 654

    Google Scholar 

  131. Knorre WA, Strassburger J, Guthke R, Fünfstück R, Günther K, Müller A, Stein G (1988) Biomed Biochim Acta 47: 667–680

    PubMed  CAS  Google Scholar 

  132. Keller H, Follath F (1988) Miscellaneous antibiotics. In: Dukes MNG (Hrsg.) Meyler’s side effects of drugs, Elsevier, Amsterdam New York Oxford, S. 543–566

    Google Scholar 

  133. De Broe ME, Giuliano RA, Verpooten GA (1986) Am J Med 80 (Suppl 6B): 115–118

    Article  PubMed  Google Scholar 

  134. Gomez A, Martos F, Garcia R, Perez B, Sanchez de la Cuesta F (1989) Pharmacol Toxicol 64: 190–192

    Article  PubMed  CAS  Google Scholar 

  135. Ebel S (1977) Handbuch der Arzneimittelanalytik, Verlag Chemie, Weinheim, New York, S. 110–116

    Google Scholar 

  136. Dibbern HW (1978) UV- und IR-Spektren wichtiger pharmazeutischer Wirkstoffe, Editio Cantor, Aulendorf, Nr. 106

    Google Scholar 

  137. Santavy F, Walterova D, Hruban L (1972) Collect Czech Chem Commun 37: 1825–1850

    Article  CAS  Google Scholar 

  138. Herzfeldt CD (1980) Pharm Ztg 125: 608–614

    CAS  Google Scholar 

  139. Osol A, Kleckner L (1952) J Am Chem Assoc 41: 306–309

    CAS  Google Scholar 

  140. Brune K (1983) Am J Med 75 (Suppl 5A): 19–23

    Article  PubMed  CAS  Google Scholar 

  141. Lorico A, Masturzo P, Villa S (1986) Biochem Pharmacol 35:2. 443–2. 445

    Google Scholar 

  142. Cleland LG, Whitehouse MW, Betts WH (1985) Drugs Exp Clin Res 11: 463–467

    PubMed  CAS  Google Scholar 

  143. Kamath BL (1975) Pharmacy, Diss Abstr Int B, Buffalo (USA) 36:1. 156–1. 157

    Google Scholar 

  144. Meyer K, Ragan C (1948) Science 108: 281

    Article  PubMed  CAS  Google Scholar 

  145. Saari WS, Raab AW, Egenhardt EL (1968) J Med Chem 11:1115–1117, zit. nach CA (1968) 88: 136296a

    Google Scholar 

  146. Elks J, Ganellin CR (1990) Dictionary of Drugs, Chapman and Hall, London New York Tokyo Melbourne Madras

    Google Scholar 

  147. Lossnitzer K (1980) Fortschr Med 98:1. 133–1. 136

    Google Scholar 

  148. Bachour G, Bender F (1985) Z Kardiol 74: 228–233

    PubMed  CAS  Google Scholar 

  149. Negwer M (1987) Organic-chemical Drugs and their Synonyms, Akademie-Verlag, Berlin

    Google Scholar 

  150. Elger W, Steinbeck H, Schillinger E, Losert W, Beier S (1986) Endocrine-pharmacological profile of gestodene, Adv Contra Delv System, Bd. 2, S. 182–197

    CAS  Google Scholar 

  151. Fachinformation Femovan (1988) Schering AG

    Google Scholar 

  152. Renier M, Buytaert P (1991) Contraception 43: 413–421

    Article  PubMed  CAS  Google Scholar 

  153. Fioretti P, Fruzzetti F, Navalesi R, Ricci C, Miccoli R, Cerri M, Melis GB (1989) Contraception 40: 649–663

    Article  PubMed  CAS  Google Scholar 

  154. Kjaer A, Lebech AM, Borggaard B, Refn H, Pedersen LR, Schierup L, Bremmelgaard A (1989) Contraception 40: 665–673

    Article  PubMed  CAS  Google Scholar 

  155. März W, Jung-Hoffmann C, Heidt F, Gross W, Kuhl H (1989) Contraception 41: 245–258

    Article  Google Scholar 

  156. Kuhnz W (1990) Am J Obstet Gynecol 163:2. 120–2. 127

    Google Scholar 

  157. Poppeo A (1969), Arzneim Forsch, 19: 352–354

    Google Scholar 

  158. Fachinformation Depostat (1988) Schering AG

    Google Scholar 

  159. Runge HM, Teufel G, Neulen J, Geyer H, Pfleiderer A (1986) Cancer Chemother Pharmacol 16: 58–63

    Article  PubMed  CAS  Google Scholar 

  160. Orestano F, Altwein JE (1976) Br J Urol 48: 485–491

    Article  PubMed  CAS  Google Scholar 

  161. Tunn U, Senge T (1978) Z Urol Nephrol 71: 521–528

    PubMed  CAS  Google Scholar 

  162. Guthrie D (1979) Br J Obstet Gynaecol 86: 497–500

    Article  PubMed  CAS  Google Scholar 

  163. Engelhardt W, Penning W, Nagy M (1977) Med Klin 72:2. 077–2. 080

    Google Scholar 

  164. Palanca E, Juco W (1977) Curr Med Res Opin 4: 513–520

    Article  PubMed  CAS  Google Scholar 

  165. Mar 29, S. 1401

    Google Scholar 

  166. Zule B, Horvat I, Kocjan R (1975) YU 74–171 23 Jan 1974, zit. nach CA 83 (23):193650g

    Google Scholar 

  167. Reuter N, Meyer F (1976) Arzneim Forsch 26:1. 201–1. 205

    Google Scholar 

  168. Ambrosiani E, Costa FV, Bracchetti D (1979) Int J Clin Pharmacol Biopharm 17: 416–420

    Google Scholar 

  169. Kesteloot H, Brasseur L, Carlier J, Demanet JC, Andriange M, Bataille G, Collignon O, Cosyns J, Vancrombreucq JC, van Durme JP, Willems J, Foucart G (1969) Acta Cardiol 24: 409–425

    Article  PubMed  CAS  Google Scholar 

  170. Rietbrock N, Woodcock BG, Hrazdil U (1984) Arzneim Forsch 34: 915–917

    CAS  Google Scholar 

  171. Clarke’s Isolation and Identification of Drugs (1986) 2. Aufl., The Pharmaceutical Press, London, S. 638

    Google Scholar 

  172. Dibbern HW (1978) UV- und IR-Atlas wichtiger pharmazeutischer Wirkstoffe, S. 107

    Google Scholar 

  173. Tawakkoi MS, Mohamed E, Ibrahim MA (1981) Pharmazie 36: 163

    Google Scholar 

  174. Tournet MC, Girre C, Fournier PE (1981) J Chromatogr 224: 348–352

    Article  CAS  Google Scholar 

  175. Mouzin G, Cousse H, Autin JM (1980) Synthesis:54

    Google Scholar 

  176. Negwer M (1987) Organic-chemical Drugs and their Synonyms, Akademie-Verlag, Berlin

    Google Scholar 

  177. Deppermann D (1978) Med Forum 2: 27

    Google Scholar 

  178. Hasselblatt A (1982) Z Allg Med 58: 1. 384

    Google Scholar 

  179. Gylfe E, Hellman B, Sehlin J, Täljedal IB (1984) Experientia 40: 1. 126

    Article  Google Scholar 

  180. Boyd AE, Aguilar-Bryan L, Nelson DA (1990) Am J Med 89: 3S–10S

    Article  PubMed  Google Scholar 

  181. Cocks TM, King SJ, Angus JA (1990) Br J Pharmacol 100: 375–378

    Article  PubMed  CAS  Google Scholar 

  182. McGuinness OP, Cherrington AD (1990) Am J Med 89: 26S–37S

    Article  Google Scholar 

  183. Joost HG (1985) TIPS 6: 239–241

    CAS  Google Scholar 

  184. Haslbeck M (1984) Endocrines Pankreas: Diabetes mellitus. In: Kümmerle HP, Hitzenberger G, Spitzy H (Hrsg.) Klinische Pharmakologie, 4. Aufl., ecomed, München, IV-448, S. 1–28

    Google Scholar 

  185. Salhanick AL, Leighty SJ, Amatruda JM (1989) Horm Metab Res 21: 596–601

    Article  PubMed  CAS  Google Scholar 

  186. Waysbort J, Regitz G, Chaimowitz D, Tuval M, Nakash I, Brunner D (1988) Clin Ther 10: 358–371

    PubMed  CAS  Google Scholar 

  187. Coppack SW, Lant AF, McIntosh CS, Rodgers AV (1990) Br J Clin Pharmacol 29: 673–684

    Article  PubMed  CAS  Google Scholar 

  188. Groop L, Wahlin-Boll E, Groop PH, Tötterman KJ, Melander A, Tolppanen EM, Fyhrqvist F (1985) Eur J Clin Pharmacol 28: 697

    Article  PubMed  CAS  Google Scholar 

  189. Bachmann W (1982) Dtsch Med Wochenschr 107: 163–169

    Article  PubMed  CAS  Google Scholar 

  190. Traumann KJ, Hösl W, Grom E, Wittemann G (1982) Dtsch Med Wochenschr 107: 180–184

    Article  PubMed  CAS  Google Scholar 

  191. Stradner F, Pieber T, Toplak H, Schreiber U, Pfeiffer KP (1990) Schweiz Med Wochenschr 120: 989–994

    PubMed  CAS  Google Scholar 

  192. Knick B (1984) Spektrum Antidiabetika, Aesopus, Zug, S. 30–48

    Google Scholar 

  193. Jackson JE, Bressler R (1981) Drugs 22: 211–245, 295–320

    Article  Google Scholar 

  194. Stowers JM, Borthwick LJ (1977) Drugs 14: 41–56

    Article  PubMed  CAS  Google Scholar 

  195. Dinnendahl V, Fricke U (Hrsg.) (1987) Glibenclamid. In: Arzneistoff profile, Govi, Frankfurt

    Google Scholar 

  196. Downs GE, Linkewich JA, DiPalma JR (1981) Geriatrics 36: 45–48

    PubMed  CAS  Google Scholar 

  197. Seltzer HS (1981) Adverse drug interactions of clinical importance to diabetics. In: Rifkn H, Raskin P (Hrsg.) Diabetes mellitus, Bd. 5, Brady, S. 327–334

    Google Scholar 

  198. Hansen JM, Christensen LK (1977) Drugs, 13: 24–34

    Article  PubMed  CAS  Google Scholar 

  199. Waldhäusel W (1984) In: Kümmerle HP, Hitzenberger G, Spitzy KH (Hrsg.) Klinische Pharmakologie, ecomed, München, S. 15–28

    Google Scholar 

  200. Schmitt EW,Nijssen J (1978) Med Welt29(NF):1. 170–1. 174

    Google Scholar 

  201. Florkowski CM, Richardson MR, Le-Guen C, Jennings PE, O’Donnell MJ, Jones AF, Lunec J, Barnett AH (1988) Diabetes Res 9: 87–90

    PubMed  CAS  Google Scholar 

  202. Larkins RG, Jerums G, Taft JL, Godfrey H, Smith IL, Martin TJ (1988) Diabetes Res Clin Pract 4: 81–87

    Article  PubMed  CAS  Google Scholar 

  203. Akanuma Y, Kosaka K, Kanazawa Y, Kasuga M, Fukuda M, Aoki S (1988) Diabetes Res Clin Pract 5:81– 90

    Google Scholar 

  204. Campbell DB, Adriaenssens P, Hopkins YW, Gordon B, Williams JRB (1980) Pharmacokinetics and metabolism of gliclazide: a review. In: Royal Soc of Medicine (Hrsg.) Gliclazide and the Treatment of Diabetes, Intern Congress and Symposium Series No 20, S. 71–82

    Google Scholar 

  205. International monitoring of adverse reactions to drugs. Report Type A (1983) Gliclazide 275, WHO Collaborating Centre For International Drug Monitoring

    Google Scholar 

  206. Kuo BS, Korner G, Bjornsson TD (1988) J Clin Invest 81: 730–737

    Article  PubMed  CAS  Google Scholar 

  207. Groop L, Wahlin-Boll E, Groop PH, Tötterman KJ, Melander A, Tolppanen EM, Fyhrqvist F(1985) Eur J Clin Pharmacol 28: 697

    Google Scholar 

  208. Kobayashi KA, Bauer LA, Horn JR, Opheim K, Wood F jr, Kradjan WA (1988) Clin Pharm 7: 224–228

    PubMed  CAS  Google Scholar 

  209. Kradjan WA, Kobayashi KA, Bauer LA, Horn JR, Opheim KE, Wood FJ jr (1989) J Clin Pharmacol 29:1. 121–1. 127

    Google Scholar 

  210. International monitoring of adverse reactions to drugs. Report Type A (1983) Glipizide 275–276, WHO Collaborating Centre For International Drug Monitoring

    Google Scholar 

  211. Jackson JE, Bressler R (1981) Drugs 22: 211–246, 295–320

    Article  Google Scholar 

  212. Kopitar Z, Koss FW (1975) Arzneim Forsch 25: 1. 933

    Google Scholar 

  213. Zilker T, Hales CN, Siddle K, Bottermann P (1975) Therapiewoche 35: 4. 615

    Google Scholar 

  214. Haslbeck M (1984) Antidiabetika. In: Kümmerle HP, Goossens N (Hrsg.) Klinik und Therapie der Nebenwirkungen, Thieme, Stuttgart, S. 305–348

    Google Scholar 

  215. Knick B (1984) Spektrum Antidiabetika, Aesopus, Zug, S. 30–48

    Google Scholar 

  216. Schloβmann K (1974) Arzneim Forsch 24: 392–397

    Google Scholar 

  217. Speck U, Mützel W, Kolb KH, Acksteiner B, Schulze PE (1974) Arzneim Forsch 24: 404–409

    CAS  Google Scholar 

  218. Schöffling K, Kroneberg G, Laudahn G (1974) Pro-Diaban® (Glisoxepid). Ber Symp, Berlin 1973, Schattauer, Stuttgart New York

    Google Scholar 

  219. Kiesselbach NHK, Blumenbach L, Lehnert J (1974) Arzneim Forsch 24: 447–452

    CAS  Google Scholar 

  220. Knick B (1984) Spektrum Antidiabetika, Aesopus, Zug

    Google Scholar 

  221. Von Heyden GmbH (Breuer H, Schoenhofen DE, Straub H, Treuner UD, Erf.) DOS. 3, 328, 047 (9.2.1984), zit. nach CA (1984) 101: 38265

    Google Scholar 

  222. Negwer M (1987) Organic-chemical Drugs and their Synonyms, Akademie-Verlag, Berlin

    Google Scholar 

  223. Auterhoff H (1976) Lehrbuch der pharmazeutischen Chemie, Wissenschaftliche Verlagsgesellschaft mbH, Stuttgart

    Google Scholar 

  224. Dibbern HW (1978) UV- und IR-Spektren wichtiger pharmazeutischer Wirkstoffe, Editio Cantor, Aulendorf

    Google Scholar 

  225. Stacey M (1939) J Chem Soc 1. 529–1. 531

    Google Scholar 

  226. Hardegger E, Spitz D (1950) Helv Chim Acta 33: 337–342

    Article  CAS  Google Scholar 

  227. Marsh RD (1951) Proc Biochem Soc [Biochem J] 50: X I

    Google Scholar 

  228. Mehltretter CL, Alexander BH, Mellies RL, Rist CE (1951) J Am Chem Soc 73:2. 424–2. 427

    Google Scholar 

  229. Benjamin DG, Kapranos SW (1953) US Pat. 2627520

    Google Scholar 

  230. Phillips GO, Moody GJ (I960) J Chem Soc 762–768

    Google Scholar 

  231. Mehltretter CL (1961) US Pat. 3012041

    Google Scholar 

  232. Iinuma F, Hiraga Y, Kinoshita T, Watanabe M (1979) Chem Pharm Bull 27:1. 268–1. 271

    Google Scholar 

  233. Schepartz AI, Fleischmann RA, Cisle JH (1972) J Chromatogr 69: 411–415

    Article  CAS  Google Scholar 

  234. Hicks KB, Lim PC, Haas MJ (1985) J Chromatogr 319: 159–171

    Article  CAS  Google Scholar 

  235. Raunhardt O, Schmidt HWH, Neukom H (1967) Helv Chim Acta 50:1. 267–1. 274

    Google Scholar 

  236. Negwer M (1987) Organic-chemical Drugs and their Synonyms, Akademie-Verlag, Berlin

    Google Scholar 

  237. Kline, Cox, (1961) J Org Chem 26: 1854

    Article  CAS  Google Scholar 

  238. Steinmetz OK, Meakins JL (1991) Can J Surg 34: 207–215

    PubMed  CAS  Google Scholar 

  239. Ziegler TR, Benfell K, Smith RJ, Young LS, Brown E, Ferrari-Baliviera E, Lowe DK, Wilmore DW (1990) J Par Enteral Nutr 14: 137–146

    Article  Google Scholar 

  240. Lacey JM, Wilmore DW (1990) Nutrition Rev 48: 297–309

    Article  CAS  Google Scholar 

  241. Minami H, Morse EL, Adibi SA (1992) Gastroenterology 103: 3–11

    PubMed  CAS  Google Scholar 

  242. Hoppe B, Martens J (1984) Chemie in unserer Zeit 3: 73–86

    Article  Google Scholar 

  243. Fahnenstich R, Heese J, Tanner H (1974) Aminosäuren. In: Bartholomé E, Biekert E, Hellmann H, Ley H (Hrsg.) Ullmanns Enzyklopädie der technischen Chemie, 4. Aufl., Bd. 7, Verlag Chemie, Weinheim, S.430– 431

    Google Scholar 

  244. Eigene Messungen

    Google Scholar 

  245. Horsley W, Sternlicht H, Cohen JS (1970) J Am Chem Soc 92: 680–686

    Article  CAS  Google Scholar 

  246. Bowman RE, Stroud HH (1959) Journal of the Chemical Society 1342–1345

    Google Scholar 

  247. Levy AL, Chung D (1955) J Am Chem Soc 77: 2899–2900

    Article  CAS  Google Scholar 

  248. Gish DT, Carpenter FH (1953) J Am Chem Soc 75: 950–952

    Article  CAS  Google Scholar 

  249. King FE, Kidd DAA (1949) Journal of the Chemical Society: 3315–3319

    Google Scholar 

  250. Wieland T et al (1958) Methoden zur Herstellung und Umwandlung von Aminosäuren und Derivaten. In: Müller E (Hrsg.) Methoden der org. Chem. (Houben-Weyl), Band XI/2, 4. Aufl., Georg Thieme Verlag Stuttgart, S. 269–509

    Google Scholar 

  251. Edman P (1950) Acta Chemica Scandinavica 4: 277–282

    Article  CAS  Google Scholar 

  252. Robinson MB, Coyle JT (1987) FASEB J 1: 446–455

    PubMed  CAS  Google Scholar 

  253. Watkins JC, Evans RH (1981) Ann Rev Pharmacol Toxicol 21: 165–204

    Article  CAS  Google Scholar 

  254. Mudge GH (1985). In: Gilman AG, Godman LS, Rall TW, Murad F (Hrsg.) Godman and Gilman’s The pharmacological basis of therapeutics, Macmillan, New York, S. 866

    Google Scholar 

  255. Christensen HN (1990) Physiol Rev 70: 43–77

    PubMed  CAS  Google Scholar 

  256. Bremer HJ, Duran M, Kamerling JP, Przyrembel H, Wadman SK (1981) Disturbances of amino acid metabolism: Clinical chemistry and diagnosis, Urban & Schwarzenberg, Baltimore München

    Google Scholar 

  257. Gutman AB, Yü TF (1973) Am J Med 54: 713

    Article  PubMed  CAS  Google Scholar 

  258. Levy HL, Barkin E (1971) J Lab Clin Med 78: 517–523

    PubMed  CAS  Google Scholar 

  259. Pratt O (1976) Adv Exp Biol Med 69: 55–75

    Article  CAS  Google Scholar 

  260. Morgan JL, Whittaker VP (1966) Biochem J 98: 128–137

    Google Scholar 

  261. Godman LS, Gilman A (1955) The pharmacological basis of therapeutics, Macmillan, New York, S. 202

    Google Scholar 

  262. Tagmann E, Sury E, Hoffmann K (1952) Helv Chim Acta 35:1. 541–1. 548

    Google Scholar 

  263. Doornbos DA, de Zeeuw RA (1969) Pharm Weekblad 104: 233–251

    CAS  Google Scholar 

  264. Weslowski JW, Blang SM, Chin TF, Lach JL (1965) J Pharm Sci 57: 811–815

    Article  Google Scholar 

  265. Kala H, Sicker B (1973) Pharmazie 28: 647–651

    PubMed  CAS  Google Scholar 

  266. Berry DJ (1973) J Chromatogr 86: 89–105

    Article  PubMed  CAS  Google Scholar 

  267. Editorial (1976) Br Med J 1:1. 424–1. 425

    Google Scholar 

  268. Ellenhorn MJ, Barceloux DG (1988) Medical Toxicology. Diagnosis and treatment of human poisoning. Elsevier, New York Amsterdam London, S. 591–593

    Google Scholar 

  269. Covington TR, Di Palma JR, Hussar DA, Lasagna L, Tatro DS, Whitsett TL (1988) Drug facts and comparisons. In: Kastrup EK, Olin BR, Connell SI (Hrsg.) Lippincott Co., St. Louis, S. 1. 091–1. 093

    Google Scholar 

  270. Curry SH, Gordon JS, Riddall D, Simpson P, Binns TB, Rondel RK, McMartin C (1971) Clin Pharmacol Ther 12: 849–857

    PubMed  CAS  Google Scholar 

  271. Hansen AR, Kennedy KA, Ambre JJ, Fischer LJ (1977) New Engl J Med 212: 250–252

    Google Scholar 

  272. Kennedy KA, Fischer LJ (1979) Drug Metab Dispos 7: 319–324

    PubMed  CAS  Google Scholar 

  273. Crow JW, Lain P, Bochner F, Shoeman DW, Azarnoff DL (1977) Clin Pharmacol Ther 22: 458–464

    PubMed  CAS  Google Scholar 

  274. Evans MA, Nies AS, Watson JT, Harbison RD (1977) J Anal Toxicol 1: 229–232

    CAS  Google Scholar 

  275. Klaus W (1984) Besonderheiten der Arzneitherapie in der Schwangerschaft. In: Fülgraff G, Palm D (Hrsg.) Pharmakotherapie, Klinische Pharmakologie, Fischer, Stuttgart, S. 315–323

    Google Scholar 

  276. Greenwood RH, Prunty FTG, Silver J (1973) Br Med J 1: 643–645

    Article  PubMed  CAS  Google Scholar 

  277. Wright N, Roscoe P (1970) J Am Med Assoc 214: 1. 704–1. 706

    Google Scholar 

  278. Cook EF, Martin EW (Hrsg.) Remington’s Practice of Pharmacy, 9. Aufl., The Mack Publishing Company, Easton, PA, S.611

    Google Scholar 

  279. Olah GA, Narang SC, Pearson RL, Cupas CA (1978) Synthesis 6: 452–453

    Article  Google Scholar 

  280. Hakimelahi GH, Sharghi H, Zarrinmayeh H, Khalafi- Nezhad A (1984) Helv Chim Acta 67 (3): 906–915

    Article  CAS  Google Scholar 

  281. Kubikowski F (1987) Chemik 40(10):292–296; zit. nach CA 109(25):229634b

    Google Scholar 

  282. Golding P, Millar RW, Paul NC, Richards DH (1988) Tetrahedron Lett 29(22):2. 731–2. 734

    Google Scholar 

  283. Musumarra G, Scarlata G, Cirma G, Romano G, Palazzo S, Clementi S, Guilietta G (1985) J Chromatogr 350 (1): 151–168

    PubMed  CAS  Google Scholar 

  284. Ermer E (1973) Pharm Ztg 118(49):1. 989–1. 991

    Google Scholar 

  285. Rosseel MT, Bogaert MG (1973) J Pharm Sci 62: 754–758

    Article  PubMed  CAS  Google Scholar 

  286. Hetman JS (1973) Fresenius Z Anal Chem 264 (2): 159–164

    Article  CAS  Google Scholar 

  287. Page DP, Carson NA, Buhr CA, Flinn PE, Wells CE, Randall MT (1975) J Pharm Sci 64: 140–147

    Article  PubMed  CAS  Google Scholar 

  288. Needleman P, Corr PB, Johnson EM (1985) In: Gilman AG, Goodman LS, Rall TW, Murad F (Hrsg.) The Pharmacological Basis of Therapeutics, 7. Aufl., Macmillan, New York, S. 806–825

    Google Scholar 

  289. Ferrer MI, Bradley SE, Wheeler HO, Enson Y, Preiseg R, Brickner PW, Conroy RJ, Harvey RM (1966) Circulation 33: 357–373

    Article  PubMed  CAS  Google Scholar 

  290. Loos D, Schneider R, Schörner W (1983) Z Kardiol 72 (Suppl 3): 29–32

    PubMed  Google Scholar 

  291. Silber S (1986) Innere Med 13: 26–31

    Google Scholar 

  292. Jaffe AS, Roberts R (1982) Pharmacotherapy 2: 273–280

    PubMed  CAS  Google Scholar 

  293. Schröder H, Schrör K (1988) Haemostaseologie 8: 90–99

    Google Scholar 

  294. Servant D, Delaforge M, Ducrocq C, Mansuy D, Lenfant M (1989) Biochem Biophys Res Commun 163: 1210–1216

    Article  Google Scholar 

  295. McDonald BJ, Bennett BM (1990) Can J Physiol Pharmacol 68: 1552–1557

    Article  PubMed  CAS  Google Scholar 

  296. Chung SJ, Fung HL (1990) J Pharmacol Exp Ther 253: 614–619

    PubMed  CAS  Google Scholar 

  297. Kukovetz WR, Holzmann S, Wurm A, Pöch G (1979) Naunyn-Schmiedeberg’s Arch Pharmacol 310: 29–138

    Google Scholar 

  298. Waldman SA, Murad F (1987) Pharmacol Rev 39: 163–196

    PubMed  CAS  Google Scholar 

  299. Rapoport R, Draznin MB, Murad F (1982) Proc Nat Acad Sci USA 79: 6470–6474

    Article  PubMed  CAS  Google Scholar 

  300. Walter U (1989) Rev Physiol Biochem Pharmacol 113: 41–88

    Article  PubMed  CAS  Google Scholar 

  301. Blayney LM, Gapper PW, Newby AC (1991) Biochem J 273: 803–806

    PubMed  CAS  Google Scholar 

  302. Ahlner J, Axelsson K, Karlsson JOG, Andersson GG (1988) Life Sci 43: 1241–1248

    Article  PubMed  CAS  Google Scholar 

  303. Moncada S, Palmer RMJ, Higgs EA (1991) Pharmacol Rev 43: 109–142

    PubMed  CAS  Google Scholar 

  304. Furchgott RF, Zawadzki JV (1980) Nature 288: 373–376

    Article  PubMed  CAS  Google Scholar 

  305. Harrison DG, Armstrong ML, Freiman PC, Heistad DD (1987) J Clin Invest 80: 1808–1811

    Article  PubMed  CAS  Google Scholar 

  306. Creager MA, Cooke JP, Mendelssohn ME, Gallagher SJ, Coleman SM, Loscalzo J, Dzau VH (1990) J Clin Invest 86: 228–234

    Article  PubMed  CAS  Google Scholar 

  307. Benet LZ, Steiner LB (1985) In: Gilman AG, Goodman LS, Rall TW, Murad F (Hrsg.) The Pharmacological Basis of Therapeutics, 7. Aufl., Macmillan, New York, S. 1663–1733

    Google Scholar 

  308. Brien JF, McLaughlin BE, Breedon TH, Bennett BM, Nakatsu K, Marks GS (1986) J Pharmacol Exp Ther 237: 608–614

    PubMed  CAS  Google Scholar 

  309. Needleman P (1975) Biotransformation of organic nitrates. In: Needleman P (Hrsg.) Handbuch der Experimentellen Pharmakologie, Bd. 40, Springer Verlag, Berlin, S. 57–96

    Google Scholar 

  310. Doyle MP, Hoekstra JW (1981) J Inorg Biochem 14: 351–358

    Article  PubMed  CAS  Google Scholar 

  311. BAz (1990) 43:1029

    Google Scholar 

  312. Mülsch A, Busse R, Winter I, Bassenge E (1989) Naunyn-Schmiedeberg’s Arch Pharmacol 339: 568–574

    Article  PubMed  Google Scholar 

  313. Molina CR, Andresen JW, Rapoport RM, Waldman S, Murad F (1987) J Cardiovasc Pharmacol 10: 371–378

    Article  PubMed  CAS  Google Scholar 

  314. Hagers Handb Pharm Praxis (1958) Band 1, Suppl. 2, S. 759

    Google Scholar 

  315. Wagner O (1951) Z Tropenmed Parasitol 3: 47–65

    PubMed  CAS  Google Scholar 

  316. Rollo IM (1965) Drugs used in the chemotherapy of amebiasis. In: Goodman LS, Gilman A (Hrsg.) The pharmacological basis of therapeutics, McMillan, New York, S. 1. 118

    Google Scholar 

  317. Steck EA (1971) WRAIR, Washington 1: 339–354

    Google Scholar 

  318. Berberian DA, Dennis EW, Pipkin CA (1950) Am J Trop Med 30: 613–623

    CAS  Google Scholar 

  319. Pérez Santiago E, Hernández Morales F (1950) Puerto Rico J Publ Health Trop Med 25: 419–422

    Google Scholar 

  320. Kibble RM (1969) Aust Vet J 45: 387

    Article  PubMed  CAS  Google Scholar 

  321. Cole M, Scheulein M, Kerwin DM (1966) Arch Int Med 117: 706–711

    Article  CAS  Google Scholar 

  322. Sah PPT (1953) J Am Chem Soc 75: 2512

    Article  CAS  Google Scholar 

  323. US Pat. 2,940,899 (1960)

    Google Scholar 

  324. Franko BV, Lunsford CD (1960) J Med Pharm Chem 2: 523–540

    Article  Google Scholar 

  325. Paasivirta J, Penttilä A, Andersen L (1975) Finn Chem Lett:94–96

    Google Scholar 

  326. Lippold BC, Schneider G (1974) Arch Pharm 307: 63–73

    Article  CAS  Google Scholar 

  327. Daldrup T, Susanto F, Michalke P (1981) Fresenius Z Anal Chem 308: 412–427

    Article  Google Scholar 

  328. Kaempe B (1974) Arch Pharm Chemi Sci Ed 2: 145–152

    CAS  Google Scholar 

  329. Daldrup T, Michalke P, Boehme W (1982) Chromatogr Newsl 10: 1–7

    CAS  Google Scholar 

  330. De Schutter JA, De Moerloose P (1988) J Chromatogr 437: 83–95

    Article  PubMed  Google Scholar 

  331. De Schutter JA, De Moerloose P (1988) J Chromatogr 450: 337–342

    Article  PubMed  Google Scholar 

  332. De Schutter JA, De Moerloose P (1988) J Pharm Biomed Anal 6: 879–885

    Article  PubMed  Google Scholar 

  333. Benoit E, Leroy P, Nicolas A (1985) Ann Pharm Fr 43: 177–182

    PubMed  CAS  Google Scholar 

  334. Anagnostopoulou PI, Koupparis MA (1986) Anal Chem 58: 322–326

    Article  PubMed  CAS  Google Scholar 

  335. Murray GR, Calvey TN, Williams NE, Chan K (1984) J Chromatogr 308: 143–151

    Article  PubMed  CAS  Google Scholar 

  336. Kle82

    Google Scholar 

  337. Kramer et al (1964) Arzneim Forsch 14: 377

    CAS  Google Scholar 

  338. Held M, Scheible G (1981) Arzneim Forsch 31:1. 036–1. 038

    Google Scholar 

  339. HW Dibbern (1991), UV- und IR-Spektren wichtiger pharmazeutischer Wirkstoffe, 509

    Google Scholar 

  340. Wirth W, Gloxhuber C (1985) Toxikologie, Thieme, Stuttgart New York, S. 187, 197

    Google Scholar 

  341. Wong GG et al (1985) Science 228: 810–815

    Article  PubMed  CAS  Google Scholar 

  342. Cantrell MA et al (1985) Proc Natl Acad Sci 82: 6250–6254

    Article  PubMed  CAS  Google Scholar 

  343. Caracciolo D,Clark S,Rovera G(1989) Br J Haematol 72:306–311

    Google Scholar 

  344. Lord BI, Gurney H, Chang J, Thatcher N, Crowther D, Dexter TM (1992) Int J Cancer 50: 26–31

    Article  PubMed  CAS  Google Scholar 

  345. Cushley W,Harnett MM (1993) Biochem J 292: 313–332

    Google Scholar 

  346. Herrmann F, Schulz G, Lindemann A, Meyenburg W, Oster W, Krumwieh D, Mertelsmann R (1989) J Clin Oncol 7: 159–167

    PubMed  CAS  Google Scholar 

  347. Kelleher C, Miyauchi J, Wong G, Clark S, Minden MD, McCulloch EA (1987) Blood 69: 1498–1503

    PubMed  CAS  Google Scholar 

  348. Metcalf D, Begley CG, Johnson GR, Nicola NA, Vadas MA, Lopez AF, Williamson DJ, Wong GG, Clark SC, Wang EA (1986) Blood 67: 37–45

    PubMed  CAS  Google Scholar 

  349. Dedhar S, Gaboury L, Galloway P, Eaves C (1988) Proc Nat Acad Sci US 85: 9253–9257

    Article  CAS  Google Scholar 

  350. Grabstein KH, Urdal DL, Tushinski J, Mochizuki DY, Price UG, Cantrell MA, Gillis S, Conlon PJ (1986) Science 232: 506–508

    Article  PubMed  CAS  Google Scholar 

  351. Rapoport AP, Abboud CN, DiPersio JF (1992) Blood Rev 6: 43–57

    Article  PubMed  CAS  Google Scholar 

  352. Lopez AF, Williamson DJ, Gamble R, Begley CG, Harlan JM, Klebanoff SJ, Waltersdorph A, Wong G, Clark SC, Vadas MA (1986) J Clin Invest 78: 1220–1228

    Article  PubMed  CAS  Google Scholar 

  353. Denzlinger C, Kapp A, Grimberg M, Gerhartz HH, Wilmanns W (1990) Blood 76: 1765–1770

    PubMed  CAS  Google Scholar 

  354. Denzlinger C, Tetzloff W, Gerhartz HH, Pokorny R, Sagebiel S, Haberl C, Wilmanns W (1993) Blood 81: 2007–2013

    PubMed  CAS  Google Scholar 

  355. Endo Y, Kibuchi T, Takeda Y, Nitta Y, Rikiishi H, Kumagai K (1992) Immunol Lett 33: 9–14

    Article  PubMed  CAS  Google Scholar 

  356. Cebon J, Dempsey P, Fox R, Kannaourakis G, Bonnern E, Burgess AW, Morstyn G (1988) Blood 72: 1340–1347

    PubMed  CAS  Google Scholar 

  357. Cebon J, Bury RW, Lieschke GJ, Morstyn G (1990) Eur J Cancer 26: 1064–1069

    Article  PubMed  CAS  Google Scholar 

  358. Shadduck RK, Waheed A, Evans C, Sulecki C, Rosenfeld CS (1990) Exp Hematol 18: 601

    Google Scholar 

  359. Stute N, Huhn RD, Furman WL, Evans WE (1991) Clin Pharmacol Ther 49: 197

    Google Scholar 

  360. Lieschke GJ, Maher D, O’Connor M, Green M, Sheridan W, Rallings M, Bonnem E, Burgess AW, McGrath (1990) Cancer Res 50: 606–614

    PubMed  CAS  Google Scholar 

  361. Metcalf D (1985) Science 229: 16–22

    Article  PubMed  CAS  Google Scholar 

  362. Donahue RE, Wang EA, Kaufman RJ, Foutch L, Leary AC, Witek-Giannetti JS, Metzger M, Hewick RM, Steinbrink DR, Shaw G, Kamen R, Clark SC (1986) Effects of N-linked carbohydrate on the in vivo properties of human GM-CSF, Cold Spring Harbor Symp Quant Biol 51: 685–692

    Article  PubMed  CAS  Google Scholar 

  363. Hill ADK, Redmond HP, McCarthy J, Croke DT, Grace PA, Bouchier-Hayes D (1992) Br J Surg 79:459 (abstr)

    Google Scholar 

  364. Nemunaitis J, Rabinowe SN, Singer JW, Bierman PJ, Vose JM, Freedman AS, Onetto N, Gillis S, Oette D, Gold M (1991) New Engl J Med 324: 1773–1778

    Article  PubMed  CAS  Google Scholar 

  365. Zimmerli W, Zarth A, Gratwohl A, Nissen C, Speck B (1989) Lancet I: 494–495

    Article  Google Scholar 

  366. Delannoy A (1992) J Int Med 231: 269–271

    Article  CAS  Google Scholar 

  367. Kuipers EJ, Vallenga E, de Wolf JT, Hazenberg BP (1992) J Rheumatol 19: 621–622

    PubMed  CAS  Google Scholar 

  368. Shechter GP (1992) Ann Int Med 116: 1033

    Google Scholar 

  369. Groopman JE, Mitsuyasu RT, DeLeo MJ, Oette DH, Golde DW (1987) New Engl J Med 317: 593–598

    Article  PubMed  CAS  Google Scholar 

  370. Nothdurft W, Selig C, Fliedner TM, Hintz-Obertreis P, Kreja L, Krumwieh D, Kurrle R, Seiler FR, Weinsheimer W (1992) Int J Radiat Biol 61: 519–531

    Article  PubMed  CAS  Google Scholar 

  371. Grant SM, Heel RC (1992) Drugs 43: 516–560

    Article  PubMed  CAS  Google Scholar 

  372. Cosman D (1988) Immunol Today 9: 97–98

    Article  PubMed  CAS  Google Scholar 

  373. Visani G, Tosi P, Finelli C, Gamberi B, Zauli G, Genacchi A, Fogli M, Colombini R, Tura S (1992) Haematologica 77: 142–145

    PubMed  CAS  Google Scholar 

  374. Antman KS, Griffin JD, Elias A, Socinski MA, Ryan L, Cannistra SA, Oette D, Whitley M, Frei E, Schnipper LE (1988) New Engl J Med 319: 593–598

    Article  PubMed  CAS  Google Scholar 

  375. Raychaudhuri SP, Fiori MM (1992) J Am Acad Dermatol 27: 451

    Article  PubMed  CAS  Google Scholar 

  376. Lieschke GJ, Burgess AW (1992) New Engl J Med 327: 28–35

    Article  PubMed  CAS  Google Scholar 

  377. Lieschke GJ, Maher D, Cebon J, O’Connor M, Green M, Sheridan W, Boyd A, Rallings M, Bonnem E, Metcalf D (1989) Ann Int Med 110: 357–364

    PubMed  CAS  Google Scholar 

  378. Cebon J, Lieschke GJ, Bury RW, Morstyn G (1992) Br J Haematol 80: 144–150

    Article  PubMed  CAS  Google Scholar 

  379. Hazenberg BPC, van Leeuwen MA, van Rijswijk MH, Stern AC, Vallenga E (1989) Blood 74: 2769–2770

    PubMed  CAS  Google Scholar 

  380. Kelly R, Marsden RA, Bevan D (1993) Br J Dermatol 128: 468–469

    Article  PubMed  CAS  Google Scholar 

  381. Young MR, Lozano Y, Djordjevic, Derata S, Matthews J, Young ME, Wright MA (1993) Int J Cancer 53: 667–671

    Article  PubMed  CAS  Google Scholar 

  382. Monahan MW, Rivier J (1972) Biochem Biophys Res Commun 48: 1100

    Article  PubMed  CAS  Google Scholar 

  383. Coy DH, Ether J, Schally AV (1975) Methods Enzymol. 37: 416

    Article  PubMed  CAS  Google Scholar 

  384. Rich DH, Gurwara SK (1975) Tetrahedron Letters 301

    Google Scholar 

  385. Geiger R, Schröder HG Ger. pat. 2, 313, 737 (1973 Hoechst)

    Google Scholar 

  386. Copsey DN, Delmatte SYJ Genetically engineered human therapeutic drugs, Pantech Partners, Stockton Press

    Google Scholar 

  387. Schally AV, Arimura A, Baba Y, Nair RMG, Matsuo H, Redding TW, Debeljuk L, White WF (1971) Biochem Biophys Res Commun 43: 393

    Article  PubMed  CAS  Google Scholar 

  388. Adelman JP, Mason AJ, Hayflick S, Seeburg PH (1986) Proc Nat Acad Sci US 83: 179–183

    Article  CAS  Google Scholar 

  389. Marshall JC, Kelch RP (1986) New Engl J Med 315: 1459–1468

    Article  PubMed  CAS  Google Scholar 

  390. Kuret JE, Murad F (1990) Adenohypophyseal hormones and related substances. In: Gilman AG, Rall TW, Nies AS, Taylor P (Hrsg.) Goodman and Gilman’s The Pharmacological Basis of Therapeutics, Pergamon Press, New York, S. 1352–1354

    Google Scholar 

  391. NN (1991) Gonadorelin (hydrochloride). In: Dollerey SC (Hrsg.) Therapeutic drugs, Churchill-Livingstone, New York, Edinb. London, Melborne

    Google Scholar 

  392. Abboud CF (1986) Mayo Clin Proc 61: 35–48

    Article  PubMed  CAS  Google Scholar 

  393. Dutta AS, Furr BJA, Giles MB, Valcaccia B (1978) J Med Chem 21: 1018–1024

    Article  PubMed  CAS  Google Scholar 

  394. Chrisp P, Goa KL (1991) Drugs 41: 254–288

    Article  PubMed  CAS  Google Scholar 

  395. Nicholson RI, Walker KJ, Turkes A, Turkes AO, Dyas J, Blamey RW, Campbell FC, Robinson MR, Griffiths K (1984) J Steroid Biochem 20: 129–135

    Article  PubMed  CAS  Google Scholar 

  396. Furr BJA, Hutchinson FG (1985) Biodegradable sustained release formulation of the LH-RH analogue Zoladex for the treatment of hormone responsive tumors. In: Schroder FH, Richards B (Hrsg.) EORTC genitourinary Group Monograph 2 Part A, Alan R Liss Inc., New York, S. 143–153

    Google Scholar 

  397. Clayton RN, Bailey LC, Cottam J, Arkell D, Perren TJ, Blackledge BR (1985) Clin Endocrinol 22: 453–462

    Article  CAS  Google Scholar 

  398. Perren TJ, Clayton N, Blackledge G, Bayley LC, Holder G, Lynch SS, Arkell DG, Cottam J, Farrar D, Young CH (1986) Cancer Chemother Pharmacol 18: 39–43

    Article  PubMed  CAS  Google Scholar 

  399. Barnfield DJ, Barker YK, Knott S, Miles GS, Warrander A (1988) Pharm Weekbl Sci Edit 10:abstr 56

    Google Scholar 

  400. Adam HK, Barker Y, Hutchinson FG, Milsted RAV, Moore RH (1988) Pharm Weekbl Sci Edit 10: 57

    Google Scholar 

  401. Barnfield DJ, Warrander A (1988) Pharm Weekbl Sci Edit 10: 56

    Google Scholar 

  402. Waymont B, Lynch TH, Dunn JA, Emtage LA, Arkell DG, Wallace DM, Blackledge GR (1992) Br J Urol 69: 614–620

    Article  PubMed  CAS  Google Scholar 

  403. Blamey RW, Jonat W, Kaufmann M, Bianco AR, Namer M (1992) Eur J Cancer 28A: 810–815

    Article  Google Scholar 

  404. West CP, Lumsden MA, Hillier H, Sweeting V, Baird DT (1992) Human Reprod 7: 328–332

    CAS  Google Scholar 

  405. Shaw RW (1992) Fertil Steril 58: 265–272

    PubMed  CAS  Google Scholar 

  406. Reichel RP, Schweppe KW (1992) Fertil Steril 57: 1197–1202

    PubMed  CAS  Google Scholar 

  407. Bassi F, Serio M (1990) Drugs Exp Clin Res 16 (Suppl): 33–37

    PubMed  Google Scholar 

  408. Sperti C, Pasquali C, Catalani S, Cappellazzo F, Bonadimani B, Militello C, Pedrazzoli S (1992) Eur J Surg Oncol 18: 267–271

    PubMed  CAS  Google Scholar 

  409. Allegretti A, Lionetto R, Saccomanno S, Paganuzzi M, Onetto M, Martinoli C, Rollandi G, Marugo M, Fazzuoli L, Pugliese V (1993) Oncology 50: 77–80

    Article  PubMed  CAS  Google Scholar 

  410. Hipkin LJ (1992) J R Army Med Corp 138: 15–18

    CAS  Google Scholar 

  411. Bressler LR, Murphy CM, Shevrin DH, Warren RF (1993) Ann Pharmacother 27: 182–185

    PubMed  CAS  Google Scholar 

  412. Vercellini P, Vendola N, Colombo A, Passadore C, Trespidi L, Crosignani PG (1992) Gynecol Obstet Invest 34: 102–104

    Article  PubMed  CAS  Google Scholar 

  413. Devogelaer JP, Nagant de Deuxchaisnes C, Clerckx F, Donnez J (1990) Gynecol Endocrinol 4 (Suppl 2):114 abstr 207

    Google Scholar 

  414. Zoladex, Standardinformation für Krankenhausapotheker, ICI-Pharma

    Google Scholar 

  415. Firmenmitteilung, ICI-Pharma (1991)

    Google Scholar 

  416. Brewer GA (1979) Ana 8, S. 179–218

    CAS  Google Scholar 

  417. Drews J (1979) Grundlagen der Chemotherapie, Springer, Wien New York, S. 100

    Book  Google Scholar 

  418. Grove SF (1963) Quart Rev Chem Soc 17: 1

    Article  CAS  Google Scholar 

  419. Brossi A, Baumann M, Gerecke M, Kyburz E (1960) Helv Chim Acta 18: 2. 071

    Google Scholar 

  420. Harris CM, Roberson IS, Harris TM (1976) J Am Chem Soc 98: 5. 380

    Google Scholar 

  421. Florey K (Hrsg.) (1972-1986) Analytical Profiles of Drug Substances, Bd. 8, 1. Aufl., Academic Press, New York London, S.219ff

    Google Scholar 

  422. Holbrook A, Bailey F, Bailey GM (1963) J Pharm Pharmacol Suppl 15: 274T

    Google Scholar 

  423. Neely WC, McDuffie IR (1972) J Assoc Off Anal Chem 55: 1300

    PubMed  CAS  Google Scholar 

  424. Grisham LM, Wilson L, Bensch K (1973) Nature 244: 294–296

    Article  PubMed  CAS  Google Scholar 

  425. Polak A (1990) Mode of action studies. In: Ryley JF (Hrsg.) Chemotherapy of fungal diseases, Springer- Verlag, Berlin Heidelberg New York, S. 153–182

    Chapter  Google Scholar 

  426. Kucers A, Bennett NMCK (1987) Griseofulvin. In: Kucers A, Bennett NMCK (Hrsg.) The use of antibiotics, J.B. Lippincott, Philadelphia, S. 1528–1533

    Google Scholar 

  427. Mar 29, S. 425

    Google Scholar 

  428. Lin C, Symchowicz S (1975) Drug Metabol Rev 4: 75–95

    Article  CAS  Google Scholar 

  429. del Palacio-Hernandez A, Lopez-Gomez S, Gonzalez-Lastra F, Moreno-Palancar P, Iglesias-Diez L (1990) Clin Exp Dermatol 15: 210–216

    Article  PubMed  Google Scholar 

  430. Piepponen T, Blomqvist K, Brandt H, Havu V, Hollinen A, Kohtamaki K, Lehtonen L, Turjanmaa K (1992) J Antimicrob Chemother 29: 195–205

    Article  PubMed  CAS  Google Scholar 

  431. Mion G, Verdon R, Le-Gulluche Y, Carsin H, Garcia A, Guilbaud J (1989) Lancet 2: 1331

    Article  PubMed  CAS  Google Scholar 

  432. Lecky BR (1990) Lancet 335: 230–231

    Article  PubMed  CAS  Google Scholar 

  433. DeCarli L, Larizza L (1988) Mut Res 195: 93–126

    Google Scholar 

  434. Marchetti F, Tiveron C, Bassani B, Pacchierotti F (1992) Mutât Res 266: 151–166

    Article  PubMed  CAS  Google Scholar 

  435. Mar 29, S.346

    Google Scholar 

  436. Cote J (1990) J Am Acad Dermatol 22: 124–125

    Article  PubMed  CAS  Google Scholar 

  437. Dibbern HW (1978), UV- und IR-Spektren wichtiger pharmazeutischer Wirkstoffe, Editio Cantor, Aulendorf

    Google Scholar 

  438. Widdicombe JG (1978) Br Med Bull 34: 57–61

    PubMed  CAS  Google Scholar 

  439. Robinson RE, Cummings WR, Deffenbaugh ER (1977) Curr Ther Res 22: 284–296

    Google Scholar 

  440. Thomson ML, Pavia D, McNical MW (1973) Thorax 28: 742–747

    Article  PubMed  CAS  Google Scholar 

  441. Kuhn JJ, Hendley JO, Adams KF, Clark JW, Gwaltney JN (1982) Chest 82: 713–718

    Article  PubMed  CAS  Google Scholar 

  442. Görlich HD, Köhler M (1990) Therapiewoche 40: 591–596

    Google Scholar 

  443. Bürgi H (1974) Scand J Resp Dis 90 (Suppl): 81–85

    Google Scholar 

  444. Hirsch SR, Viernes PF, Kory RC (1973) Chest 63: 9–14

    Article  PubMed  CAS  Google Scholar 

  445. Check JH, Adelson HG, Wu CH (1982) Fert Steril 37: 707–708

    CAS  Google Scholar 

  446. Vandenheuvel WJA, Smith JL, Silber RH (1972) J Pharm Sci 61:1. 997–1. 998

    Google Scholar 

  447. Kurz H (1989) Antitussiva und Expektoranzien, Wiss Verl Ges, Stuttgart

    Google Scholar 

  448. Kokkola K, Vaara J (1976) Curr Ther Res 19: 397–404

    PubMed  CAS  Google Scholar 

  449. Brinkmann O (1980) Med Welt 31: 304–305

    PubMed  CAS  Google Scholar 

  450. Ramsdell CM, Kelley WN (1973) Ann Intern Med 78: 239–242

    PubMed  CAS  Google Scholar 

  451. Metheson CE, Murphy JE, Gibson SH, Moffitt S (1982) Drug Intell Clin Pharm 16: 332–334

    Google Scholar 

  452. UII (1980) Bd. IV, 18: 226

    Google Scholar 

  453. DRPP 305281, 167211

    Google Scholar 

  454. McClure W (1962) J Org Chem 27: 267

    Google Scholar 

  455. Sobrero J (1843) Ann 48: 19

    Google Scholar 

  456. Béhal A, Choay E (1893) CR hebd Séances Acad Sci 116: 197

    Google Scholar 

  457. Lewis P (1947) US Pat 2.433.277 CA (1948) 42: 2103h

    Google Scholar 

  458. Ruban VF, Belen’kii AB, Gurevich AYa, Belen’kii BG (1989) J Chromatogr 467 (1):41–47, zit. nach CA (1989) 111: 186626x

    Google Scholar 

  459. Eichholtz F (1942) Lehrbuch der Pharmakologie, Springer, Berlin, S. 476

    Google Scholar 

  460. Span. Pat. (1966) 1,042,207, zit. nach CA (1966) 65: 16922

    Google Scholar 

  461. Tang Q, Ling D (1986) Yaowu Fenxi Zazhi 6:202–204, zit. nach CA (1986) 105:172133y

    Google Scholar 

  462. Span. Pat. (1966) 1,042,207, zit. nach CA (1966) 65: 16922

    Google Scholar 

  463. Tang Q, Ling D (1986) Yaowu Fenxi Zazhi 6:202–204, zit. nach CA (1986) 105:172133y

    Google Scholar 

  464. Inotsume N, Nakano M (1988) Chem Pharm Bull 36:3. 692–3. 695

    Google Scholar 

  465. Houlihan WJ, Manning RE, Sandoz-Wander, Inc. (1976) US 3982020; zit. nach CA 85:177101q

    Google Scholar 

  466. Kodama JK, Haynes GR, Albert JR, Shell Oil Co. (1976) US 3975533; zit. nach CA 85:130539y

    Google Scholar 

  467. Shearer CM, De Angelis NJ (1979) J Pharm Sci 68:1. 010–1. 012

    Google Scholar 

  468. Sidhu AS, Kennedy JM, Deeble S (1987) J Chromatogr 391: 233–242

    Article  PubMed  CAS  Google Scholar 

  469. VioL, Mamolo MG, Furlan G (1988) Farmaco 43:27–36; zit. nach CA 108:226957c

    Google Scholar 

  470. De Angelis L (1979) Med Actual 15:481–486; zit. nach CA 92:135170a

    Google Scholar 

  471. McMahon FG (1984) The centrally acting alpha2 agonists. In: McMahon FG (Hrsg.) Management of essential hypertension: The new low dose era, Futura Publishing Company, Mount Kisco New York, S. 215–276

    Google Scholar 

  472. Wendt RL (1980) Guanabenz. In: Scriabine A (Hrsg.) Pharmacology of antihypertensive drugs, Raven Press, New York, S. 99–111

    Google Scholar 

  473. Baum T, Shropshire AT, Rowles G, van Pelt R, Fernandez SP, Eckfeld DK, Gluckman MI (1970) J Pharmacol ExpTher 171: 276–287

    PubMed  CAS  Google Scholar 

  474. Holmes B, Brogden RN, Heel RC, Speight TM, Avery GS (1983) Drugs 26: 212–229

    Article  PubMed  CAS  Google Scholar 

  475. Sherman GP (1972) Am J Pharm 144: 110–115

    PubMed  CAS  Google Scholar 

  476. Walker BR, Deitch MW, Gold JA, Levey BA (1982) J Int Med Res 10: 131–139

    PubMed  CAS  Google Scholar 

  477. Walker BR, Schneider BE, Gold JA (1980) Curr Ther Res 27: 786–796

    Google Scholar 

  478. Kaplan NM (1984) J Cardiovasc Pharmacol 6: s841–s846

    Article  PubMed  Google Scholar 

  479. Kaplan NM, Grundy S (1988) Clin Pharmacol Ther 44 (3): 297–302

    Article  PubMed  CAS  Google Scholar 

  480. Baum T, Shropshire AT (1976) Eur J Pharmacol 37: 31–44

    Article  PubMed  CAS  Google Scholar 

  481. Weber MA, Graettinger WF, Cheung DG (1990) Centrally acting sympathetic inhibitors. In: Laragh JH, Brenner BM (Hrsg.) Hypertension: Pathophysiology, Diagnosis and Management, Raven Press, New York, S. 2. 251–2. 261

    Google Scholar 

  482. Bauer JH, Burch RN (1983) Cardiovasc Rev Rep 4: 9–17

    Google Scholar 

  483. Fuller RW, Snoddy HD, Marshall WS (1977) J Pharm Pharmacol 29: 375–376

    Article  PubMed  CAS  Google Scholar 

  484. Baum T, Shropshire AT (1976) Aspects of the antihypertensive action of indoramin and guanabenz. In: Scriabine A, Sweet CS (Hrsg.) New antihypertensive drugs, Spectrum Publications, New York, S. 369–386

    Google Scholar 

  485. Natoff IL, Katzung BG, Weir F, Kodama JK (1968) Pharmacologist 10: 157

    Google Scholar 

  486. Scholtysik G (1974) Naunyn-Schmiedeberg’s Arch Pharmacol (Suppl)282:R86

    Google Scholar 

  487. Farnebo LO, Hamberger B (1974) J Pharm Pharmacol 26: 644–646

    Article  PubMed  CAS  Google Scholar 

  488. Baum T, Shropshire AT (1970) J Pharmacol Exp Ther 9: 503–506

    CAS  Google Scholar 

  489. Meacham RH, Emmett M, Kyriakopoulos AA, Chiang ST, Ruelius HW, Walker BR, Narins RG, Goldberg M (1980) Clin Pharmacol Ther 27: 44–52

    Article  PubMed  CAS  Google Scholar 

  490. De Marchi G, Gomarasca P, Marmo E, Scholastico C (1974) Boll Chim Farm 113: 225–231

    PubMed  Google Scholar 

  491. Meacham RH, Chiang ST, Kick CJ, Sisewine SF, Jusko WJ, Ruelius HW (1981) Drug Metab Dispos 9: 509–514

    PubMed  CAS  Google Scholar 

  492. Mauro VF (1990) Listing of antihypertensive medications. In: Ganten D, Mulrow PJ (Hrsg.) Handbook of Experimental Pharmacology, Bd. 93, Pharmacology of Antihypertensive Therapeutics, Springer Verlag, Berlin Heidelberg, S. 859–889

    Google Scholar 

  493. Walker BR, Hare LE, Deitch MW, Gold JA (1982) Curr Ther Res 31: 746–775

    Google Scholar 

  494. Tenant FS, Rawson RA (1984) NIDA Res Monogr 49: 338–343

    Google Scholar 

  495. Mulry JT (1985) Drug Intell Clin Pharm 19 (1): 32–33

    PubMed  CAS  Google Scholar 

  496. Walker BR, Hare LE, Deitch MW (1982) J Int Med Res 10: 6–14

    PubMed  CAS  Google Scholar 

  497. Ram VCS, Holland B, Fairchild C, Gomez-Sanchez CE (1979) J Clin Pharmacol 19: 148–150

    PubMed  CAS  Google Scholar 

  498. Winer N, Carter CH (1983) Clin Pharmacol Ther 31: 282–283

    Google Scholar 

  499. Hall AH, Smolinske SC, Kulig KW, Rumack BH (1985) Ann Int Med 102 (6): 787–788

    PubMed  CAS  Google Scholar 

  500. Ana

    Google Scholar 

  501. Shearer CM, DeAngelis NJ (1979) J Pharm Sci 68: 1010–1012

    Article  PubMed  CAS  Google Scholar 

  502. Bruce WF, Baum T (1969) Ger Offen 1802394;zit.nach CA 71: 6099z

    Google Scholar 

  503. Scolastico C; Tronconi G (1980) Br 7903439; zit. nach CA 97: 23486e

    Google Scholar 

  504. Hoffmann H, Zeller A (1987) Fresenius’ Z Anal Chem 326:446–448; zit. nach CA 106:182768u

    Google Scholar 

  505. Sidhu AS, Kennedy JM, Deeble S (1987) J Chromatogr 391: 233–242

    Article  PubMed  CAS  Google Scholar 

  506. Hengstmann JH, Falkner FC, Watson JT, Oates J (1974) Analytical Chemistry 46: 34–39

    Article  PubMed  CAS  Google Scholar 

  507. Rao GR, Raghuveer S (1980) Indian J Pharm Sci:141–142

    Google Scholar 

  508. Maxwel RA (1980) Guanethidine. In: Scriabine A (Hrsg.) Pharmacology of antihypertensive drugs, Raven Press, New York, S. 127–150

    Google Scholar 

  509. Maxwell RA (1982) Br J Clin Pharmacol 13: 35–44

    PubMed  Google Scholar 

  510. Louis WJ, Howes LG (1990) Guanethidine and related compounds. In: Ganten D, Mulrow PJ (Hrsg.) Handbook of Experimental Pharmacology, Bd. 93, Pharmacology of antihypertensive therapeutics. Springer Verlag, Berlin Heidelberg, S. 287–299

    Google Scholar 

  511. McMahon FG (1984) Peripheral adrenergic blocking agents. In: McMahon FG (Hrsg.) Management of essential hypertension: The new low-dose era, Futura Publishing Company, Mount Kisco New York, S. 457–494

    Google Scholar 

  512. Mar29, S.481–482

    Google Scholar 

  513. Richardson DW, Wyso EM, Magee JH, Cavell GC (1960) Circulation 22: 184–190

    Article  CAS  Google Scholar 

  514. Cohn JN, Liptak TE, Freis ED (1963) Circ Res 12: 298–307

    Article  PubMed  CAS  Google Scholar 

  515. Chang CC, Costa E, Brodie BB (1965) J Pharmacol Exp Ther 147: 303–312

    PubMed  CAS  Google Scholar 

  516. Mitchell JR, Oates JA (1970) J Pharmacol Exp Ther 172: 100–107

    PubMed  CAS  Google Scholar 

  517. Carlsson A (1966) Pharmacol Rev 18: 541–549

    PubMed  CAS  Google Scholar 

  518. Cass R, Spriggs TLB (1961) Br J Pharmacol 17: 442–450

    CAS  Google Scholar 

  519. Boura ALA, Green AF (1965) Ann Rev Pharmacol 5: 183–212

    Article  CAS  Google Scholar 

  520. Fust CI (1967) Adv Drug Res 4: 133–161

    Google Scholar 

  521. Dollery CT, Emslie-Smith D, Milne MD (1960) Lancet ii:381–387

    Google Scholar 

  522. McMartin C, Rondel RK, Vinter J, Allan BR, Humberstone PM, Leishman AWD, Sandler G, Thirkettle JL (1970) Clin Pharmacol Ther 11: 423–431

    PubMed  CAS  Google Scholar 

  523. Rahn KH (1973) Clin Neurol 1: 14–18

    CAS  Google Scholar 

  524. Hengstmann JH, Falkner FC (1979) Eur J Clin Pharmacol 15: 121–125

    Article  PubMed  CAS  Google Scholar 

  525. Rahn KH, Goldberg LI (1969) Clin Pharmacol Ther 10: 858–863

    PubMed  CAS  Google Scholar 

  526. McMartin C, Simpson P (1971) Clin Pharmacol Ther 11: 423–430

    Google Scholar 

  527. Rascher W (1985) Sympathikolytika. In: Ganten D, Ritz E (Hrsg.) Lehrbuch der Hypertonie, Schattauer Verlag, Stuttgart New York, S. 657–676

    Google Scholar 

  528. Leishman AWD, Mathews HL, Smith AJ (1959) Lancet ii: 1. 044–1. 048

    Google Scholar 

  529. Castren JA, Pohloja S (1962) Acta Ophthalmol (Copenh) 40: 348–361

    Google Scholar 

  530. Tabira T, Shibasaki H, Kuroiwa Y (1983) Arch Neurol 40: 430–432

    Article  PubMed  CAS  Google Scholar 

  531. Stone CA, Porter CC, Stavorski JM, Ludden CT, Totaro JA (1964) J Pharmacol Exp Ther 144: 196–204

    PubMed  CAS  Google Scholar 

  532. Mitchell JR, Arias L, Oates A (1967) J Am Med Ass 202: 973–976

    Article  CAS  Google Scholar 

  533. Mitchell JR, Oates JA (1970) J Pharmacol Exp Ther 172: 100–107

    PubMed  CAS  Google Scholar 

  534. Mitchell JR, Cavanaugh JH, Arias L, Oates JA (1970) J Clin Invest 49:1. 596–1. 604

    Article  Google Scholar 

  535. Palmatier MA, Schmidt RE, Plurad SB, Johnson EM jr (1987) Ann Neurol 21: 46–52

    Article  PubMed  CAS  Google Scholar 

  536. Kidd GJ, Heath JW, Dunkley PR (1986) J Neurocytol 15: 561–572

    Article  PubMed  CAS  Google Scholar 

  537. Tosunoglu S, Atmaca S (1989) Pharmazie 44: 498–499

    CAS  Google Scholar 

  538. Scholtysik G, Jerie P, Picard CW (1980) Guanfacine. In: Scriabine A (Hrsg.) Pharmacology of antihypertensive drugs, Raven Press, New York, S. 79–98

    Google Scholar 

  539. Rosenthal JH (1986) Am J Cardiol 57: 22E–26E

    Article  PubMed  CAS  Google Scholar 

  540. Magometschnigg D, Hitzenberger G, Bonelli J (1980) Br J Clin Pharmacol 10: 125s–131s

    Article  PubMed  Google Scholar 

  541. Schoeppe W, Brecht HM (1980) Br J Clin Pharmacol 10: 97s–101s

    Article  PubMed  Google Scholar 

  542. Scholtysik G, Lauener H, Eichenberger E, Bürki H, Salzmann R, Müller-Schweinitzer E, Waite R (1975) Arzneim Forsch 25:1. 483–1. 491

    Google Scholar 

  543. Dollery CT, Jerie LT (1980) Br J Clin Pharmacol 10: 1s–208s

    Article  Google Scholar 

  544. Pichler I, Kobinger W (1990) Centrally acting drugs (Clonidine, Methyldopa, Guanfacine). In: Ganten D, Mulrow PJ (Hrsg.) Handbook of Experimental Pharmacology, Bd. 93, Pharmacology of antihypertensive therapeutics, Springer Verlag, Berlin Heidelberg, S. 227–262

    Google Scholar 

  545. Waite R (1975) Inhibition of sympathetic nerve activity, resulting from central alpha-adrenoceptor stimulation. In: Milliez P, Safar M (Hrsg.) Recent advances in hypertension, Bd.II, Boehringer, Ingelheim, S. 27–31

    Google Scholar 

  546. Velly J (1977) J Pharmacol (Paris) 8: 351–360

    CAS  Google Scholar 

  547. Walland A, Kobinger W, Csongrady A (1974) Eur J Pharmacol 26: 184–190

    Article  PubMed  CAS  Google Scholar 

  548. Picard CW, Bream JB (1979) Guanfacine (BS 100-141) and related centrally acting alpha-adrenoceptor stimulants. Chemistry and structure activity relationships. In: Simkins MA (Hrsg.) Medicinal Chemistry VI., Costwold Press, Oxford, S. 45–59

    Google Scholar 

  549. Meier J, Beveridge T, Laplanche R, Kiechel JR, Ohnhaus EE (1978) Pharmacokinetics of the hypotensive agent guanfacine. In: Eighth World Congress Cardiol, Sept. 1978, Tokyo, Japan, Abstr. No. 1. 087, S. 362

    Google Scholar 

  550. Kiechel JR (1980) Br J Clin Pharmacol 10: 25S–32S

    Article  PubMed  Google Scholar 

  551. Sorkin EM, Heel RC (1986) Drugs 31: 301–336

    Article  PubMed  CAS  Google Scholar 

  552. Mauro F (1990) Listing of antihypertensive medications. In: Ganten D, Mulrow PJ (Hrsg.) Handbook of Experimental Pharmacology, Bd. 93, Pharmacology of antihypertensive therapeutics, Springer Verlag, Berlin Heidelberg, S. 861–874

    Google Scholar 

  553. Szam I, Hollo J (1982) Int J Clin Pharmacol Ther Tox 20: 388–392

    CAS  Google Scholar 

  554. Westelink K, Michotte Y (1982) Curr Med Res Opin 7: 631–638

    Article  Google Scholar 

  555. Fillingim JM, Blackshear JL, Strauss A, Strauss M (1986) Am J Cardiol 57: 50E–54E

    Article  PubMed  CAS  Google Scholar 

  556. Materson BJ, Kessler WB, Alderman MH, Canosa FL, Finnertty FA, Savran SV, McKillen JI, Marlon AM (1986) Am J Cardiol 57 (9): 32E–37E

    Article  PubMed  CAS  Google Scholar 

  557. Jerie P (1980) Br J Clin Pharmacol 10: 157s–164s

    Article  PubMed  Google Scholar 

  558. Cornish LA (1988) CI Pharm 7 (3): 187–197

    CAS  Google Scholar 

  559. Board AW, Perry VP, Shepperson BE, Nyman CE, Carchman SH (1988) Clin Ther 10 (6): 761–775

    PubMed  CAS  Google Scholar 

  560. Wilson MF, Haring O, Lewin A, Bedsole G, Stepansky W, Fillingim JM, Hall D, Roginsky M, McMahon FG, Jagger P, Strauss M (1986) Am J Cardiol 57 (9): 43E–49E

    Article  PubMed  CAS  Google Scholar 

  561. Jerie P (1986) Am J Cardiol 57: 55E–59E

    Article  PubMed  CAS  Google Scholar 

  562. Houston MC (1981) Am Heart J 102: 415–430

    Article  PubMed  CAS  Google Scholar 

  563. Physicians Desk Reference (1989) Tenex® (Guanfacine hydrochloride), Product Overview, Medical Economic Company, Oradel, N.J., S. 1.709–1. 711

    Google Scholar 

  564. Rote Liste (1990) Editio Cantor, Aulendorf/Württ

    Google Scholar 

  565. Thatte UM, Gupta KC, Satoskar RS (1986) Pharmacology 33 (5): 292–300

    Article  PubMed  CAS  Google Scholar 

  566. Jerie P (1980) Br J Clin Pharmacol 10: 37s–47s

    Article  PubMed  Google Scholar 

  567. Dibbern HW, Wirbitzki E (1991) UV- und IR-Spektren wichtiger pharmazeutischer Wirkstoffe, Editio Cantor Aulendorf, FfM

    Google Scholar 

  568. Negwer M (1987) Organic-chemical Drugs and their Synonyms, Akademie-Verlag, Berlin

    Google Scholar 

  569. Davoll J (1958) J Chem Soc 1593–1598

    Google Scholar 

  570. Davoll J, Lythgoe B, Todd AR (1948) J Chem Soc 1685–1686

    Google Scholar 

  571. Davoll J, Lowra BA (1951) J Am Chem Soc 73: 1650–1655

    Article  CAS  Google Scholar 

  572. Beil Erg. Werk 4, Bd. 26, Teil 6, S. 3901

    Google Scholar 

  573. Levene PA, Bass LW (1931) Nucleic Acids 163, New York

    Google Scholar 

  574. Beil Bd. 31, S. 28–29

    Google Scholar 

  575. Graselli JG, Ritchey WM (Hrsg.) CRC Atlas of spectral data and physical constants for organic compounds, Bd. 3,2 Aufl., CRC Press Inc. Cleveland, Ohio

    Google Scholar 

  576. Negwer M (1987) Organic-chemical Drugs and their Synonyms, Akademie-Verlag, Berlin

    Google Scholar 

  577. Tsuhako M, Fujimoto M, Oshashi S, Nariai H, Moboka I (1984) Bull. Chem. Soc. Jpn 57: 3274–3280

    Article  CAS  Google Scholar 

  578. Beil Erg. Werk 4, Bd.26, Teil 6, S. 3909

    Google Scholar 

  579. Negwer M (1987) Organic-chemical Drugs and their Synonyms, Akademie-Verlag, Berlin

    Google Scholar 

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Authors and Affiliations

  1. Institut für Pharmakologie, Freie Universität Berlin, Thielallee 69-73, 14195, Berlin, Germany

    Professor Dr. F. von Bruchhausen

  2. Institut für Pharmazie und Lebensmittelchemie, Universität Würzburg, Am Hubland, 97074, Würzburg, Germany

    Professor Dr. S. Ebel

  3. Pharmakologisches Institut, Universität Heidelberg, Im Neuenheimer Feld 366, 69120, Heidelberg, Germany

    Professor Dr. E. Hackenthal

  4. Institut für Pharmazie, Johannes Gutenberg-Universität, Staudinger Weg 5, 55128, Mainz, Germany

    Professor Dr. G. Dannhardt

  5. Lehrstuhl für Pharmazeutische Chemie Pharmazeutisches Institut, Universität Freiburg, Hermann-Herder-Str.9, 79104, Freiburg, Germany

    Professor Dr. A. W. Frahm

  6. Pharmazeutisches Institut, Universität Bonn, Kreuzbergweg 26, 53115, Bonn, Germany

    Professor Dr. U. Holzgrabe

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Editors and Affiliations

  1. Institut für Pharmakologie, Freie Universität Berlin, Thielallee 69-73, 14195, Berlin, Germany

    F. von Bruchhausen

  2. Institut fur Pharmazie und Lebensmittelchemie, Universität Würzburg, Am Hubland, 97074, Würzburg, Germany

    S. Ebel

  3. Pharmakologisches Institut, Universität Heidelberg, Im Neuenheimer Feld 366, 69120, Heidelberg, Germany

    E. Hackenthal

  4. Institut für Pharmazie, Johannes Gutenberg-Universität, Staudinger Weg 5, 55128, Mainz, Germany

    G. Dannhardt

  5. Lehrstuhl für Pharmazeutische Chemie Pharmazeutisches Institut, Universitat Freiburg, Hermann-Herder-Str.9, 79104, Freiburg, Germany

    A. W. Frahm

  6. Pharmazeutisches Institut, Universität Bonn, Kreuzbergweg 26, 53115, Bonn, Germany

    U. Holzgrabe

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© 1993 Springer-Verlag Berlin Heidelberg

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von Bruchhausen, F. et al. (1993). Gabexat. In: von Bruchhausen, F., et al. Hagers Handbuch der Pharmazeutischen Praxis. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-57994-3_3

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