Skip to main content

Hypericum erectum Thunb. (St. John’s Wort): In Vitro Culture and the Production of Procyanidins

  • Chapter
Medicinal and Aromatic Plants VI

Part of the book series: Biotechnology in Agriculture and Forestry ((AGRICULTURE,volume 26))

Abstract

Some Hypericum species have been used as traditional medicinal plants in various parts of the world. Examples are H. erectum Thunb. in Japan (Okuda 1986) and H. japonicum Thunb. and H. perforatum L. in China. Among them, H. perforatum is one of the oldest European medicinal plants, described in The Greek Herbal of Dioscorides published in the 1st century. This plant was also very popular for its supposed magical properties, and was used on St. John’s day, from which the trivial name, St. John’s wort, was derived.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 189.00
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 249.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 329.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  • Akamatsu K (1966) Hypericum erectum In: Wakanyaku. Ishiyaku, Tokyo, p 228

    Google Scholar 

  • Brockmann H, Pohl F, Maier K, Hashad MH (1942) Hypericin, the photodynamic pigment of St. John’s bread (Hypericum perforatum). Ann 553:1–52

    CAS  Google Scholar 

  • Broda B, Andrzejewska E (1966) Choline content in some medicinal plants. Farm. Polska 22:181–184

    CAS  Google Scholar 

  • Cellarova E, Kimakova K, Brutovska R (1992) Multiple shoot formation and phenotypic changes of regenerants in Hypericum perforatum L. Acta Biotecnol. 12:445–452

    Article  Google Scholar 

  • Chandra B, Lakshmi V, Srivastava OP, Kapil RS (1989) In vitro antifungal activity of constituents of Hypericum mysorense Heyne against Trichophyton mentagrophytes. Indian Drugs 26:678–679

    CAS  Google Scholar 

  • Chaplinskaya MG (1956) The composition of Hypericum perforatum grass. Nekotorye Voprosy Farm Sbornik: 269–273 (Referat Zhur Khim, Biol Khim 1957 Abstr 17825)

    Google Scholar 

  • Chen MT, Chen CM (1985) Xanthones from Hypericum sompsonii. Heterocycles 23:2543–2548

    Article  CAS  Google Scholar 

  • Dragendorff G (1898) Hypericum perforatum L. In: Die Heilpflanzen der verschiedenen Völker und Zeiten. Enke, Stuttgart, p 437

    Google Scholar 

  • Ishiguro K, Yamaki M, Takagi S, Yamagata Y, Tomita K (1985) X-ray crystal structure of sarothralin, a novel antibiotic compound from Hypericum japonicum. J Chem Soc Chem Commun: 26–27

    Google Scholar 

  • Jiangsu Xinyi Xueyuan (ed) (1978) Xiao Lian giao. In: Zhong-yao Da-ci-dian 1 Commercial Press, Hong Kong, p 254

    Google Scholar 

  • Kakiuchi N, Hattori M, Namba T, Nishizawa M, Yamagishi T, Okuda T (1985) Inhibitory effect of tannins on reverse transcriptase from RNA tumor virus. J Nat Prod 48:614–621

    Article  PubMed  CAS  Google Scholar 

  • Kakiuchi N, Kusumoto I, Hattori M, Namba T, Hatano T, Okuda T (1991) Effects of condensed tannins and related compounds on reverse transcriptase. Phytother Res 5:270–272

    Article  CAS  Google Scholar 

  • Kameda K, Takaku T, Okuda H, Kumura T, Okuda T, Hatano T (1987) Inhibitory effect of various flavonoids isolated from leaves of persimmon on angiotensin-converting enzyme activity. J Nat Prod 50:680–683

    Article  PubMed  CAS  Google Scholar 

  • Kariyone T, Kawano N (1952) Microchemical study of plant components X. Hypericin the photodynamic pigment of St. John’s bread. Yakugaku Zasshi 73:204–205

    Google Scholar 

  • Kolodziejski J, Gill S (1960) Flavonoids species of the genus Hypericum I. Chromatographic analysis of flavones. Diss Pharm 12:311–323

    CAS  Google Scholar 

  • Kosuge T, Ishida H, Satoh T (1985) Studies on antihemorrhagic substances in herbs classified as hemostatics in Chinese medicine IV. On antihemorrhagic principles in Hypericum erectum Thunb. Chem Pharm Bull 33:202–205

    Article  CAS  Google Scholar 

  • Lavie D, Meruelo D, Lavie G, Revl M, Vande VV, Rotman D (1989) Antiviral compositions containing aromatic polycyclic diones for treating retrovirus infections. PCT Int Appl WO 8901, 329, 23rd Feb (Cl. A61K31/05)

    Google Scholar 

  • Linsmaier EM, Skoog F (1965) Organic growth factor requirements of tobacco tissue cultures. Physiol Plant 18:100–127

    Article  CAS  Google Scholar 

  • Michaluk A (1961a) Flavonoids in species of the genus Hypericum II. The flavonols. Diss Pharm 13:73–79

    CAS  Google Scholar 

  • Michaluk A (1961b) Leucoanthocyanidins in Hypericum perforatum. Diss Pharm 13:81–88

    CAS  Google Scholar 

  • Michaluk A, Brunarska Z, Bednarska D (1956) Tannins and flavones in different species of Hypericum. Diss Pharm 8:47–62

    CAS  Google Scholar 

  • Miura Y, Fukui H, Tabata M (1987) Clonal propagation of chemically uniform fennel plants through somatic embryoids. Planta Med 53:92–94

    Article  PubMed  CAS  Google Scholar 

  • Miura Y, Fukui H, Tabata M (1988) Reduced inhomogeneity of Angelica acutiloba plants propagated clonally through somatic embryoids. Planta Med 54:79–81

    Article  PubMed  CAS  Google Scholar 

  • Morimoto S, Nonaka G, Nishioka I (1986) Tannins and related compounds XXXVIII. Isolation and characterization of flavan-3-ol glucoside and procyanidin oligomers from cassia bark (Cinnamomum cassia Blume). Chem Pharm Bull 34:633–642

    Article  CAS  Google Scholar 

  • Okuda T (1986) Hypericum erectum Thunb. In: Encyclopedia of natural medicine. Hirokawa, Tokyo, pp 67–68

    Google Scholar 

  • Okuda T, Mori K, Terayama K, Higuchi K, Hatano T (1979) Isolation of geraniin from plants of Geranium and Euphorbiaceae. Yakugaku Zasshi 99:543–545

    PubMed  CAS  Google Scholar 

  • Okuda T, Yoshida T, Hatano T, Kuwahara M, Iida S (1982) Inhibitory effect of crude drugs on proteases. Tannin and related polyphenols. Proc Symp Wakanyaku 15:111–118

    CAS  Google Scholar 

  • Okuda T, Yoshida T, Hatano T, Yazaki K, Ikegami Y, Shingu T (1987) Guavins A, C, and D complex tannins form Psidium guajava. Chem Pharm Bull 35:443–446

    Article  CAS  Google Scholar 

  • Okuda T, Yoshida T, Hatano T (1991) Chemistry and biological activity of tannins in medicinal plants. In: Wagner H, Farnsworth NR (eds) Economic and medicinal plant research, vol 5. Academic Press, London, pp 129–165

    Google Scholar 

  • Salgues R (1961) Chemistry and toxicology of the genus Hypericum. Qual Plant Mater Veg 8:38–64

    Article  CAS  Google Scholar 

  • Shibutani S, Nagasawa T, Oura H, Nonaka G, Nishioka I (1983) Mechanism of the blood urea nitrogen-decreasing activity of rhatannin from rhei rhizoma in the rat I. Chem Pharm Bull 31:2378–2385

    Article  PubMed  CAS  Google Scholar 

  • Thompson RS, Jacques D, Haslam E, Tanner RJN (1972) Plant procyanidins part I. Introduction; the isolation, structure and distribution in nature of plant procyanidins. J Chem Soc Perkin Trans 1:1387–1399

    Google Scholar 

  • Yazaki K, Okuda T (1990) Procyanidins in callus and multiple shoot cultures of Hypericum erectum. Planta Med 56:490–491

    Article  PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 1994 Springer-Verlag Berlin Heidelberg

About this chapter

Cite this chapter

Yazaki, K., Okuda, T. (1994). Hypericum erectum Thunb. (St. John’s Wort): In Vitro Culture and the Production of Procyanidins. In: Bajaj, Y.P.S. (eds) Medicinal and Aromatic Plants VI. Biotechnology in Agriculture and Forestry, vol 26. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-57970-7_11

Download citation

  • DOI: https://doi.org/10.1007/978-3-642-57970-7_11

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-63420-8

  • Online ISBN: 978-3-642-57970-7

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics