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The Pharmacology of Sleep pp 29–45Cite as

Principles of Sleep Regulation: Implications for the Effect of Hypnotics on Sleep

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Part of the book series: Handbook of Experimental Pharmacology ((HEP,volume 116))

Abstract

Three basic processes underlie sleep regulation: (a) a homeostatic process determined by sleep and waking; (b) a circadian process, a clock-like mechanism defining the alternation of periods with high and low sleep propensity and which is basically independent of sleep and waking; and (c) an ultradian process occurring within sleep and represented by the alternation of the two sleep states, non-REM sleep and REM sleep (Fig. 1). This chapter focuses on sleep homeostasis and on the ultradian dynamics, whereas the circadian aspects are covered in Chap. 3 of this volume.

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Authors
  1. A. A. Borbély
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Editors and Affiliations

  1. Sleep Research and Treatment Center, Pennsylvania State University College of Medicine M.S. Hershey Medical Center, 500 University Drive, Hershey, PA, 17033, USA

    Anthony Kales M.D. (Professor and Chairman Department of Psychiatry and Director) (Professor and Chairman Department of Psychiatry and Director)

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© 1995 Springer-Verlag Berlin Heidelberg

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Borbély, A.A. (1995). Principles of Sleep Regulation: Implications for the Effect of Hypnotics on Sleep. In: Kales, A. (eds) The Pharmacology of Sleep. Handbook of Experimental Pharmacology, vol 116. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-57836-6_2

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  • DOI: https://doi.org/10.1007/978-3-642-57836-6_2

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-63372-0

  • Online ISBN: 978-3-642-57836-6

  • eBook Packages: Springer Book Archive

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