Abstract
Development of nuclear medicine is closely related to examinations of endocrine active organs. 128lodine was one of the first artificially produced radioisotopes by Fermi in the year 1934. This isotope had already been used for studies of iodine metabolism and for experiments on the physiology of the thyroid, in 1938. In 1939 131iodine was applied in humans for the first time [14] and basic research on scintigraphic application had already been reported in 1951 [6]. While 131iodine is still used in nuclear medicine because of its property as a β-emitter, it has lost its importance for diagnosis.
This is a preview of subscription content, log in via an institution.
Buying options
Tax calculation will be finalised at checkout
Purchases are for personal use only
Learn about institutional subscriptionsPreview
Unable to display preview. Download preview PDF.
References
Abrams HL, Spiro R, Goldstein N (1950) Metastases in carcinoma: analysis of 1000 autopsied cases. Cancer 3:74–85
Ahlstrom H, Eriksson B, Bergstrom M, et al. (1995) Pancreatic neuroendocrine tumors: diagnosis with PET. Radiology 195:333–337
Bergstrom M, Muhr C, Lundberg PO, Langstrom B (1991) PET as a tool in the clinical evaluation of pituitary adenomas. J Nucl Med 32:610–615
Boland GW, Goldberg MA, Lee MJ, et al. (1995) Indeterminate adrenal mass in patients with cancer: evaluation at PET with 2-(F-18)-fluoro-deoxy-D-glucose. Radiology 194:131–134
Bustamante E, Morris HP, Pederson PL (1981) Energy metabolism of tumor cells: requirement for a form of hexokinase with a propensity for mitochondrial binding. J Biol Chem 256:8699–8704
Cassen B, Curtis L, Reed C, Libby R (1951) Instrumentation for 131I use in medical studies. Nucleonics 9:46
Farde L, Ehrin E, Eriksson L, et al. (1985) Substituted benzamides as ligands for visualization of dopamine receptor binding in the human brain by positron emission tomography. Proc Natl Acad Sci 82:3863–3867
Flier JS, Mueckler MM, Usher P, Lodish HF (1987) Elevated levels of glucose transport and transporter messenger RNA are induced by ras or src oncogenes. Science 235: 1492–1495
Foidart-Willems J, Depas G, Vivegnis D, et al. (1995) positron emission tomography and radiolabelled octreotide scintigraphy in carcinoid tumors. Eur J Nucl Med 22:635
Gallagher BM, Fowler JS, Gutterson NI, MacGregor RR, Wan CN, Wolf AP (1978) Metabolic trapping as a principle of radiopharmaceutical design. Some factors responsible for the biodistribution of (18-F) 2 deoxy-2-fluoro-D-glucose. J Nucl Med 19: 1154–1161
Gasparoni P, Rubello D, Ferlin G (1997) Potential role of fluorine-18-deoxyglucose (FDG) positron emission tomography (PET) in the staging of primitive and recurrent medullary thyroid carcinoma. J Endocrinol Invest 20:527–530
Grunwald F, Schomburg A, Bender H, et al. (1996) Fluorine-18 fluorodeoxyglucose positron emission tomography in the follow-up of differentiated thyroid cancer. Eur J Nucl Med 23:312–319
Gupta N, Bradfield H (1996) Role of positron emission tomography scanning in evaluating gastrointestinal neoplasms. Sem Nucl Med 26:65–73
Hamilton, JG, Soley MH (1939) Studies in iodine metabolism by the use of a new radioactive iodine. Amer J Physiol 127:557
Hatanaka M (1974) Transport of sugars in tumor cell membranes. Biochem Biophys Acta 355:77–104
Joensuu H, Ahonen A, Klemi PJ (1988) 18F-Fluorodeoxyglucose imaging in preoperative diagnosis of thyroid malignancy. Eur J Nucl Med 13:502–506
Joensuu H, Ahonen A (1987) Imaging of metastases of thyroid carcinoma with fluorine-18 fluorodeoxyglucose. J Nucl Med 1987:910–914
Krenning EP, Kwekkeboom DJ, Bakker WH, et al. (1993) Somatostatin receptor scintigraphy with (In- 1 1 1 -DTPA-D-Phe)- and (J-123-Tyr)-Oktreotide: The Rotterdam experience with more than 1000 patients. Eur J Nucl Med 20:716–731
Martineau R, Kohlbacher M, Shaw SN, Amos H (1972) Enhancement of hexoses entry into chick fibroblasts by starvation: differential effect on galactose and glucose. Proc Natl Acad Sci USA 69:3407–3411
Mueckler MM (1994) Facilitative glucose transporters. Eur J Biochem 219:713–725
Muhr C, Bergstrom M (1991) Positron emission tomography applied in the study of pituitary adenomas. J Endocrinol Invest 14:509–528
Muhr C, Lundberg PO, Antoni G, et al. (1984) The uptake of 11C-labeled bromocriptine and methionine in pituitary tumors studied by positron emission tomography (PET). In: Lamberts, Tilders, van der Veen, et al. (eds) Trends in Diagnosis and Treatment of Pituatary Adenomas. Amsterdam: Free University Press, pp 151–155
Murakami T, Nishiyama T, Shirotani T, et al. (1992) Type 1 glucose transporter from the mouse which are responsive to serum, growth factor, and oncogenes. J Biol Chem 267:9300–9306
Pauwels EKJ, McCready VR, Stoot JHMB, van Deurzen FP (1998) The mechanism of accumulation of tumour-localising radiopharmaceuticals. Eur J Nucl Med 25:277–305
Reuland P, Handgretinger R, Smykowsky H, et al. (1991) Application of the murine anti-Gd-2 antibody 14.Gd-2a for diagnosis and therapy of neuroblastoma. Nucl Med Biol 18:121–125
Reuland P, Geiger L, Klingebiel Th, Laniado K, Feine U, Bares R, Niethammer D, Handgretinger R (1996) Clinical impact of the different diagnostic tools for neuroblastoma. Adv Neuroblastoma Res 5:23
Rigo P, Paulus P, Kaschten BJ, Hustinx R, Bury T, Jerusalem G, Benoit T, Foidart-Willems J (1996) Oncological applications of positron emission tomography with fluorine-18 fluorodeoxyglucose. Eur J Nucl Med 23:1641–1674
Shulkin BL, Koeppe RA, Francis IR, et al. (1993) Pheochromocytomas that do not accumulate metaiodobenzylguanidine: localization with PET and administration of FDG. Radiology 186:11–15
Shulkin BL, Sisson JC, Hutchinson RJ (1994) PET FDG studies of neuroblastoma. J Nucl Med 35:135 (abstr.)
Shulkin BL, Wieland DM, Schwaiger M (1992) PET scanning with hydroxyephedrine: an approach to the localization of pheochromocytoma. J Nucl Med 33:1125–1131
Sisson JC, Thompson NW, Ackerman RJ, Wahl RL (1994) Use of 2-(F-181-fluoro-2deoxy-D-glucose PET to locate parathyroid adenomas in primary hyperparathyroidism. Radiology 192:280
Sokoloff L, Reivich M, Kennedy C, et al. (1977) The (14-C)deoxy glucose method for the measurement of local cerebral glucose utilisation: theory, procedure, and normal values in the conscious and anesthetized albino rat. J Neurochem 28:897–916
Vaidyanathan G, Affleck DJ, Zalutsky MR (1995) Validation of 4-(fluorine-18) fluoro-3iodobenzylguanidine as a positron-emitting analog of MIBG. J Nucl Med 36:644–650
Wagner NH Jr, Burns HD, Dannals RF, et al. (1983) Imaging dopamine receptors in the human brain by positron emission tomography. Science 221:1264–1266
Wahl RL, Hutchkins GD, Buchsbaum DJ, Liebert M, Grossman HB (1991) 18-F-2deoxy-2-fluoro-deoxyglucose uptake into human tumor xenografts. Cancer 76:1544–1550
Warburg O (1920) Über den Stoffwechsel der Carcinomzelle. Kolin Wochenschr Berl 4:534–536
Warburg O (1931) The metabolism of tumors. Constable, London, pp 75–327
Wieland DM, Wu JL, Brown LE, Mangner TJ, Swanson DP, Beierwaltes WM (1980) Radiolabeled adrenergic neuron blocking agents: adrenomedullary imaging with (131)iodobenzylguanidine. J Nucl Med 21:349–353
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2000 Springer-Verlag Berlin Heidelberg
About this chapter
Cite this chapter
Reuland, P., Larson, S.M. (2000). Endocrine/neuroendocrine tumors. In: Wieler, H.J., Coleman, R.E. (eds) PET in Clinical Oncology. Steinkopff, Heidelberg. https://doi.org/10.1007/978-3-642-57703-1_27
Download citation
DOI: https://doi.org/10.1007/978-3-642-57703-1_27
Publisher Name: Steinkopff, Heidelberg
Print ISBN: 978-3-642-63329-4
Online ISBN: 978-3-642-57703-1
eBook Packages: Springer Book Archive