Abstract
Positron emission tomography (PET) is a nuclear medical modality which provides quantitative tomographic images and allows one to noninvasively determine the time course of a radioactive substance in vivo. Positron emitters are used for labeling biochemical substances. After injection of the radioactive tracer, the radiation from the body is registered by external detectors and tomographic images of the tracer distribution in the body are reconstructed using mathematical algorithms. The measured intensity and time course of the activity concentration in tissue depend on the specific physiological process in which the tracer takes part. Developments in PET instrumentation aim at improving resolution and sensitivity, in order to obtain precise measurements with as little radioactivity as possible. The recent clinical success of PET promoted new developments in scanner technology, thus bringing conventional nuclear medicine and PET closer together [26].
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Ziegler, S.I. (2000). Physics, quality control. In: Wieler, H.J., Coleman, R.E. (eds) PET in Clinical Oncology. Steinkopff, Heidelberg. https://doi.org/10.1007/978-3-642-57703-1_2
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DOI: https://doi.org/10.1007/978-3-642-57703-1_2
Publisher Name: Steinkopff, Heidelberg
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