Skip to main content
SpringerLink
Log in

PET in head and neck tumors

  • Chapter
PET in Clinical Oncology

Abstract

Tumors of the head and neck region comprise a heterogeneous group of neoplastic processes. Due to the complicated anatomical situation, head and neck tumors exhibit characteristic epidemiological, pathological and therapeutic features. Despite these differences, there are certain common properties concerning the anatomy of the regional drainage of lymph nodes and lymph vessels of the head and neck, the pathology, staging and screening, as well as pertaining therapeutic approaches. As a result, the head and neck have been subdivided into the following regions: nasal cavity, paranasal sinus, nasopharynx, oral cavity, oropharynx, hypopharynx and larynx.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 39.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 54.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Adams S, Baum RP, Stuckensen T, et al. (1998) Prospective comparison of 18F-FDG PET with conventional imaging modalities (CT, MRI, US) in lymph node staging of head and neck cancer. Eur J Nucl Med 25:1255–1260

    Article  PubMed  CAS  Google Scholar 

  2. Assar OS, Fischbein NJ, Caputo GR, et al. (1999) Metastastatic head and neck cancer: role and usefullness of FDG-PET in locating occult primary tumors. Radiology 210:177–181

    Google Scholar 

  3. Bailet JW, Abemayor E, Jabour BA, et al. (1992) Positron emission tomography: a new, precise imaging modality for detection of primary head and neck tumors and assessment of cervical adenopathy. Laryngoscope. 102: 281–288

    PubMed  CAS  Google Scholar 

  4. Bender H, Straehler-Pohl HJ, Schomburg A, et al. (1997) Value of F-18-DG-PET in the assessment of head and neck tumors. J Nucl Med 38:153 (abstr)

    Google Scholar 

  5. Bender H, Straehler-Pohl HJ, Frohmann JP et al. (1998) FDG-PET as a clinical routine tool for the staging of selected tumors: results and implications In: Limouris GS, Bender H, Biersack HJ (eds) Radionuclides for therapy. Mediterra Publishers Athens

    Google Scholar 

  6. Bender H, Straehler-Pohl HJ, Linke D, et al. (1998) Klinische Bedeutung von 18FDGPET in der Diagnostik von Kopf-Hals-Tumoren. Nuklearmedizin 37:30 (abstr)

    Google Scholar 

  7. Bender H, Metten N, Bangard N, et al. (1999) Possible role of FDG-PET in the early prediction of therapy outcome in liver metastases of colorectal carcinoma. Hybridoma 18: 87–91

    Article  PubMed  CAS  Google Scholar 

  8. Braams JW, Pruim J, Freling NJ, et al. (1995) Detection of lymph node metastases of squamous-cell cancer of the head and neck with FDG-PET and MRI. J Nucl Med 36: 211–216

    PubMed  CAS  Google Scholar 

  9. Braams JW, Pruim J, Kole AC, et al. (1997) Detection of unknown primary head and neck tumors by positron emission tomography. Int J Oral Maxillofac Surg 26:112–115

    Article  PubMed  CAS  Google Scholar 

  10. Berlangieri SU, Brizel DM, Scher RL, et al. (1994) Pilot study of positron emission tomography in patients with advanced head and neck cancer receiving radiotherapy and chemotherapy. Head Neck 16:340–346

    Article  PubMed  CAS  Google Scholar 

  11. Cancer Statistics (1994) Cancer journal for clinicians. American Cancer Society 44:9–26

    Google Scholar 

  12. Donald PJ (1986) Marijuana smoking: possible cause of head and neck carcinoma in young patients. Otolaryngol Head Neck Surg 94:517–519

    PubMed  CAS  Google Scholar 

  13. Fahraeus R, Fu HL, Ernberg I, et al. (1988) Expression of Epstein-Barr virus-encoded proteins in nasopharyngeal carcinoma. Int J Cancer 42:329–331

    Article  PubMed  CAS  Google Scholar 

  14. German J (1983) Chromosome Mutation and Neoplasia. Alan R Liss, New York

    Google Scholar 

  15. Greven KM, McGuirt WF, Watson X, et al. (1995) PET in the evaluation of laryngeal carcinoma. Ann Otol Rhinol Laryngol 104:274–278

    PubMed  Google Scholar 

  16. Greven KM, Williams DW 3rd, Keyes JW Jr et al. (1994) Positron emission tomography of patients with head and neck carcinoma before and after high dose irradiation. Cancer 74:1355–1359

    Article  PubMed  CAS  Google Scholar 

  17. Haberkorn U, Strauss LG, Dimitrakopoulou A, et al. (1993) Fluorodeoxyglucose imaging of advanced head and neck cancer after chemotherapy. J Nucl Med 34:12–17

    PubMed  CAS  Google Scholar 

  18. Haberkorn U, Strauss LG, Reisser C, van Kaick G, et al. (1992) Positron emission tomography (PET) in the evaluation of tumor proliferation and follow-up of therapy in ear, nose and throat tumors. Radiologe 32:296–301

    PubMed  CAS  Google Scholar 

  19. Jabour BA, Choi Y, Hoh CK, et al. (1993) Extracranial head and neck: PET imaging with 2-[F-18]fluoro-2-deoxy-D-glucose and MR imaging correlation. Radiology 186:27–35

    PubMed  CAS  Google Scholar 

  20. Keyes JW, Harkness BA, Greven KM, et al. (1994) Salivary gland tumors: pretherapy evaluation with PET. Radiology 1992:99–102

    Google Scholar 

  21. Kole AC, Nieweg 0E, Pruim J, et al. (1998) Detection of unknown occult primary tumors using positron emission tomography. Cancer 82:1160–1166

    Article  PubMed  CAS  Google Scholar 

  22. Laubenbacher C, Saumweber D, Wagner Manslau C et al. (1995) Comparison of fluorine-18-fluorodeoxyglucose PET, MRI and endoscopy for staging head and neck squamous-cell carcinomas. J Nucl Med 36:1747–1757

    PubMed  CAS  Google Scholar 

  23. Mancuso AA, Drane WE, Mukherji SK (1994) The promise FDG in diagnosis and surveillance of head and neck cancer. Cancer 74:1193–1195

    Article  PubMed  CAS  Google Scholar 

  24. Mashberg A, Garfinkel L, Harris S (1981) Alcohol as a primry factor in oral squamous carcinoma. CA Cancer J Clin 31:146–148

    Article  PubMed  CAS  Google Scholar 

  25. McGuirt WF, Greven KM, Keyes JW et al. (1995) Positron emission tomography in the evaluation of laryngeal carcinoma. Ann Otol Rhinol Laryngol 104:274–278

    PubMed  CAS  Google Scholar 

  26. McGuirt WF, Keyes JW, Greven KM et al. (1995) Preoperative identification of benign versus malignant parotid masses: a comparative study including positron emission tomography. Laryngoscope 105:579–584

    Article  PubMed  CAS  Google Scholar 

  27. McGuirt WF, Williams DW 3rd, Keyes JW Jr, et al. (1995) A comparative diagnostic study of head and neck nodal metastases using positron emission tomography. Laryngoscope 105:373–375

    Article  PubMed  CAS  Google Scholar 

  28. Mendenhall WM, Manusco AA, Parsons JT, et al. (1998) Diagnostic evaluation of squamous cell carcinoma metastatic to cervical lymph nodes from an unknown head and neck primary site. Head-Neck 20:739–744

    Article  PubMed  CAS  Google Scholar 

  29. Minn H, Clavo AC, Grenman R, Wahl RL (1995) In vitro comparison of cell proliferation kinetics and uptake of tritiated fluorodeoxyglucose and L-methionine in squamous cell carcinoma of the head and neck. J Nucl Med 36:252–258

    PubMed  CAS  Google Scholar 

  30. Moser E, Krause T (1997) Konsensus - Onko-PET: Arbeitsausschuß Posit:ronen-Emissions-Tomographie der DGN, Vorsitz Reske SN, 2. Konsensuskonferenz in Ulm. Nudearmedizin 36:45–46

    Google Scholar 

  31. Mukherji SK, Drane WE, Mancuso AA, et al. (1996) Occult primary tumors of the head and neck: detection with 2-[F-18] fluoro-2-deoxy-D-glucose SPECT. Radiology 199:761–766

    PubMed  CAS  Google Scholar 

  32. Mukherji SK, Drane WE, Tart RP, et al. (1994) Comparison of thallium-201 and F-18 FDG SPECT uptake in squamous cell carcinoma of the head and neck. Am J Neuroradiol 15: 1837–1842

    PubMed  CAS  Google Scholar 

  33. Old LJ, Boyse EA, Oettgen, et al. (1966) Precipitating antibody in human serum to an antigen present in cultured Burkitt’s lymphoma cells. Proc Natl Acad Sci USA 56:1699–1701

    Article  PubMed  CAS  Google Scholar 

  34. Rege S, Maass A, Chaiken L, et al. (1994) Use of positron emission tomography with fluorodeoxyglucose in patients with extracranial head and neck cancers. Cancer 73: 3047–3058

    Article  PubMed  CAS  Google Scholar 

  35. Rege SD, Chaiken L, Hoh CK, et al. (1993) Change induced by radiation therapy in FDG uptake in normal and malignant structures of the head and neck: quantitation with PET. Radiology 189:807–812

    PubMed  CAS  Google Scholar 

  36. Reisser C, Haberkorn U, Strauss LG (1991) PET scan in tumor diagnosis in the head and neck. Laryngorhinootologie 70:214–217

    Article  PubMed  CAS  Google Scholar 

  37. Reisser C, Haberkorn U, Strauss LG (1992) Diagnosis of energy metabolism in ENT tumors - a PET study. HNO 40:225–231

    PubMed  CAS  Google Scholar 

  38. Reisser C, Haberkorn U, Strauss LG (1993) The relevance of positron emission tomography for the diagnosis and treatment of head and neck tumors. J Otolaryngol 22: 231–238

    PubMed  CAS  Google Scholar 

  39. Schantz SP, Harrison LB, Forastiere AA (1997) Tumors of the nasal cavity and paranasal sinuses, nasopharynx, oral cavity and orophrarunx. In: DeVita VT, Hellman S, Rosenberg SA (eds) Cancer, Principles and Practice of Oncology. Lippincott-Raven Publ New York, pp 741–801

    Google Scholar 

  40. Schantz SP, Hsu TC (1989) Head and neck cancer patients express increased clastogeninduced chromosome fragility. Head Neck 11:337–339

    Article  PubMed  CAS  Google Scholar 

  41. Schipper JH, Schrader M, Arweiler D, et al. (1996) Positron emission tomography for primary tumor detection in lymph node metastases with unknown primary tumor. HNO 44:254–257

    PubMed  CAS  Google Scholar 

  42. Seifert E, Schadel A, Haberkorn U, Strauss LG (1992) Evaluating the effectiveness of chemotherapy in patients with head-neck tumors using positron emission tomography (PET scan). HNO 40:90–93

    PubMed  CAS  Google Scholar 

  43. Shemen LJ, Klotz J, Shottenfeld D, Strong EW (1984) Increase of tongue cancer in young men. JAMA 252:1857–1859

    Article  PubMed  CAS  Google Scholar 

  44. Spitz MR, Fuegger JJ, Goeffert H, et al. (1988) Squamous cell carcinoma of the upper aerodigestive tract: a case comparison analysis. Cancer 61:203–209

    Article  PubMed  CAS  Google Scholar 

  45. Straehler-Pohl HJ, Bender H, Linke D, et al. (1998) Value of F-18-DG-PET in the assessment of head and neck tumors: clinical experience in 152 patients. J Cancer Res Clin Oncol 124:R10

    Article  Google Scholar 

  46. Straehler-Pohl HJ, Bender H, Linke D, et al. (1998) Value of F-18-DG-PET in the staging of head and neck tumors under clinical routine conditions. Eur J Nucl Med 25:1032 (abstr)

    Google Scholar 

Download references

Authors
  1. H. Bender
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. H. J. Straehler-Pohl
    View author publications

    You can also search for this author in PubMed Google Scholar

Editor information

Editors and Affiliations

  1. Bundeswehrzentralkrankenhaus Koblenz, Abteilung XV - Nuklearmedizin, Rübenacher Straße 170, Koblenz, 56072, Germany

    H. J. Wieler

  2. Division of Nuclear Medicine, Department of Radiology, DUMC 3949, Room 1419, Duke North Erwin Road, Durham, NC, 27710, USA

    R. Edward Coleman M.D. (Professor of Radiology, Vice-Chairman, Director) (Professor of Radiology, Vice-Chairman, Director)

Rights and permissions

Reprints and permissions

Copyright information

© 2000 Springer-Verlag Berlin Heidelberg

About this chapter

Cite this chapter

Bender, H., Straehler-Pohl, H.J. (2000). PET in head and neck tumors. In: Wieler, H.J., Coleman, R.E. (eds) PET in Clinical Oncology. Steinkopff, Heidelberg. https://doi.org/10.1007/978-3-642-57703-1_13

Download citation

  • DOI: https://doi.org/10.1007/978-3-642-57703-1_13

  • Publisher Name: Steinkopff, Heidelberg

  • Print ISBN: 978-3-642-63329-4

  • Online ISBN: 978-3-642-57703-1

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics

Search

Navigation