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Diagnostik und Therapie von Tachykardien mit schmalem QRS-Komplex

Diagnosis and therapy in narrow QRS tachycardia

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Summary

Emergency medicine and critical care are fields that often require rapid diagnosis and intervention for specific situations. Narrow QRS tachycardia is a cardiac rhythm with a rate faster than 100/min and a QRS duration <0.12 s. Causes of narrow QRS tachycardia (N-QRS-T) are sinus tachycardia (ST), atrial tachycardia (AT), AV nodal reentry tachycardia (AVNRT), circus movement tachycardia (CMT), atrial flutter (AFlut) and atrial fibrillation (AFib). A systematic ECG approach with evaluation of spontaneous AV block, QRS alternans, P wave location and P wave polarity permits correct identification of the underlying arrhythmia mechanism and the origin of the arrhythmia. In hemodynamically unstable N-QRS-T, electrical DC cardioversion should be performed immediately. If the hemodynamic situation is stable, vagal maneuvers (Valsalva, carotis sinus massage) are indicated; if unsuccessful, drugs are therapeutic alternatives. In ST, beta-blocking agents (metoprolol 15 mg i.v.) are successful; in AT and AVNRT adenosine (6–18 mg bolus i.v.) and ajmaline (50–100 mg i.v.) are preferred. In patients (pts) with CMT, ajmaline (50–100 mg i.v.) is an ideal drug with high success rates. When vagal maneuvers or pharmacologic interventions fail to suppress the N-QRS-T, DC cardioversion is necessary. For pts with AFib principles of therapy are restoration of sinus rhythm (RSR) or ventricular rate control. Direct current cardioversion can restore sinus rhythm in up to 90% of pts with AFib. No single agent has emerged as the drug of choice for converting AFib; however, RSR is possible with propafenone (600 mg oral), flecainide (300 mg oral) or sotalol (80–160 mg oral). Ventricular rate control is an important component in pts with AFib. Verapamil (5–10 mg i.v.) and digoxin (0.4 mg i.v.) are effective drugs in reducing resting ventricular rates in pts with established AFib. Three options are available for acute treatment of AFlut: rapid atrial pacing, DC cardioversion or administration of propafenone (600 mg oral) or flecainide (300 mg oral).

Zusammenfassung

In der Intensiv-und Notfallmedizin sind in speziellen Situationen oft schnelle diagnostische Maßnahmen und therapeutische Interventionen notwendig. Tachykardien mit schmalem QRS-Komplex (S-QRS-T) sind durch eine Herzfrequenz > 100/min und eine QRS-Breite <0,12 s definiert. S-QRS-T sind typisch für Sinus-Tachykardien (ST), atriale Tachykardien (AT), AV-Knoten-Reentry-Tachykardien (AVNRT), „circus movement“ Tachykardien bei akzessorischen Leitungsbahnen (CMT), bei Vorhofflattern (VH-Flat) und Vorhofflimmern (VH-Flim). Eine systematische EKG-Analyse mit Beurteilung von spontanem AV-Block, QRS-Alternans, P-Wellen Lokalisation und P-Wellen Morphologie erlauben eine Identifikation von Tachykardiemechanismus und -ursprungsort. Bei S-QRS-T mit instabiler Hämodynamik sollte sofort eine elektrische Kardioversion durchgeführt werden. Bei stabilen Kreislauf-Verhältnissen sind vagale Maneuver (Valsalva, Karotis-Druck-Massage) therapeutische Maßnahmen der ersten Wahl. Bei Ineffektivität sollten medikamentöse Interventionen erfolgen: Bei ST sind Betablocker (Metoprolol 5–15 mg i.v.) indiziert, bei AT und AVNRT sollten intial Adenosin (6–18 mg als Bolus i.v.) oder Verapamil (5–10 mg i.v.) appliziert werden. Bei CMT ist Ajmalin (50–100 mg i.v.) besonders effektiv. Bei Ineffektivität der medikamentösen Therapie muss die sekundäre elektrische DC-Kardioversion erfolgen. Bei VH-Flim muss therapeutisch zwischen Arrhythmieter-minierung oder Frequenzverlangsamung unterschieden werden: Für die Akuttherapie von tachykardem VH-Flim (Terminierung von VH-Flim) kommt vor allem die elektrische Kardioversion (Erfolgsrate bis zu 90%) in Betracht oder die medikamentöse Konversion mit Propafenon (600 mg oral), Flecanid (300 mg oral) oder Sotalol (80–160 mg oral). Die Frequenzverlangsamung bei persistierendem VH-Flim kann durch Verapamil (5–10 mg i.v.) und/oder Digoxin (0,4 mg i.v.) erreicht werden. Akutmaßnahmen zur Terminierung von VH-Flat sind vor allem die transvenöse rechtsatriale Überstimulation oder alternativ die elektrische DC- oder medikamentöse Kardioversion mit Propafenon (600 mg oral) oder Flecainid (300 mg).

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Trappe, HJ., Weismüller, P., Rodriguez, LM., Smeets, J.L.R.M. (2001). Diagnostik und Therapie von Tachykardien mit schmalem QRS-Komplex. In: Trappe, HJ., Schuster, HP. (eds) Die Notfalltherapie bei akuten Herzrhythmusstörungen. Steinkopff, Heidelberg. https://doi.org/10.1007/978-3-642-57631-7_3

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  • DOI: https://doi.org/10.1007/978-3-642-57631-7_3

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