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Medikamentöse Therapie der arteriellen Hypertonie

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Arterielle Hypertonie
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Zusammenfassung

Die Einleitung einer medikamentösen Behandlung der arteriellen Hypertonie wird empfohlen, wenn (s. auch Abb. 19.2)

  • Blutdruckwerte >180 mmHg systolisch und/oder > 110 mmHg diastolisch vorliegen

  • Blutdruckwerte bei wiederholten Messungen Werte von 140-180 mmHg systolisch und/oder 90-110 mmHg ergeben und gleichzeitig eine hohes oder sehr hohes kardiovaskuläres Gesamtrisiko besteht (Tabelle 7.6) oder

  • durch Allgemeinmaßnahmen bei Patienten mit mittlerem kardiovaskulären Gesamtrisiko nach drei bis sechs Monaten keine befriedigende Blutdrucksenkung (<140 mmHg systolisch und/oder <90 mmHg diastolisch) zu erzielen ist oder

  • durch Allgemeinmaßnahmen bei Patienten mit geringem kardiovaskulären Gesamtrisiko nach sechs bis zwölf Monaten keine befriedigende Blutdrucksenkung (<150 mmHg systolisch und/oder <95 mmHg diastolisch) zu erzielen ist.

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Literatur

  • Alderman MH (1993) Blood pressure management: individualized treatment based on absolute risk and the potential for benefit. Ann Intern Med 119:329–335

    PubMed  CAS  Google Scholar 

  • Brown MJ, Castaigne A, de Leeuw PW, Mancia G, Palmer CR, Rosenthal T, Ruilope LM (2000) Influence of diabetes and type of hypertension on response to antihypertensive treatment. Hypertension 35:1038–1042

    Article  PubMed  CAS  Google Scholar 

  • Brunner HR, Menard J, Waeber B, Burnier M, Biollaz J, Nussberger J, Bellet M (1990) Treating the individual hypertensive patient: considerations on dose, sequential monotherapy and drug combinations. J Hypertension 8:3–11

    Article  CAS  Google Scholar 

  • Dahlöf B, Lindholm LH, Hansson L, Schersten B, Ekbom T, Wester PO (1991) Morbidity and mortality in the Swedish trial in Old Patients with Hypertension (STOP-Hypertension). Lancet 338:1281–1285

    Article  PubMed  Google Scholar 

  • Deutsche Liga zur Bekämpfung des hohen Blutdruckes e.V. Deutsche Hypertonie Gesellschaft (2000) Empfehlungen zur Hochdruckbehandlung. Merkblatt, 16. Auflage, Heidelberg

    Google Scholar 

  • Dickerson JEC, Hingorani AD, Ashby MJ, Palmer CR, Brown MJ (1999) Optimisation of antihypertensive treatment by crossover rotation of four major classes. Lancet 353:2008–2013

    Article  PubMed  CAS  Google Scholar 

  • Fenichel RR, Lipicky RJ (1994) Combination products as first-line pharmacotherapy. Arch Intern Med 154:1429–1430

    Article  PubMed  CAS  Google Scholar 

  • Graves JW (2000) Management of difficult-to-control hypertension. Mayo Clin Proc 75:278–284

    PubMed  CAS  Google Scholar 

  • Guidelines for management of hypertension (1999) Report of the third working party of the British Hypertension Society. J Hum Hypertension 13:569–592

    Article  Google Scholar 

  • Guidelines Sub-Committee (1999) 1999 World Health Organisation-International Society of Hypertension Guidelines for the Management of Hypertension. J Hypertension 17:151–183

    Google Scholar 

  • Hansson L, Zanchetti A, Carruthers SG, Dahlöf B, Elmfeldt D, Menard J, Julius S, Rahn KH, Wedel H, Westerling S for the HOT Study Group (1998) Effects of intensive blood pressure lowering and low-dose aspirin in patients with hypertension. Principal results of the Hypertension Optimal Treatment (HOT) randomised trial. Lancet 351:1755–1762

    Article  PubMed  CAS  Google Scholar 

  • Hjemdahl P, Wiklund IK (1992) Quality of life on antihypertensive drug therapy: scientific end-point or marketing exercise? J Hypertension 10:1437–1446

    Article  CAS  Google Scholar 

  • Jones JK, Gorkin L, Lian JF, Staffa JA, Fletcher AP (1995) Discontinuation of and changes in treatment after start of new courses of antihypertensive drugs: s study of a United Kingdom population. Br Med J 311:293–295

    Article  CAS  Google Scholar 

  • Kostis JB, Espeland MA, Appel L, Johnson KC, Pierce J, Wofford JL for the Trial of Nonphar-macologic Interventions in the Elderly (TONE) Cooperative research Group (1998) Does withdrawal of antihypertensive medication increase the risk of cardiovascular events? Am J Cardiol 82:1501–1508

    Article  PubMed  CAS  Google Scholar 

  • Lacombe PS, Vicente JAG, Pages JC Morselli PL (1996) Causes and problems of nonresponse or poor response to drugs. Drugs 51:552–570

    Article  CAS  Google Scholar 

  • Lakshman MR, Reda DJ, Materson BJ, Cushman WC, Freis ED for the Department of Veterans Affairs Cooperative Study Group on Antihypertensive Agents (1999) Arch Intern Med 159:551–558

    Article  PubMed  CAS  Google Scholar 

  • Lasagna L (2000) Diuretics vs. alpha-blockers for treatment of hypertension. JAMA 283:2013–2015

    Article  PubMed  CAS  Google Scholar 

  • Materson BJ, Reda DJ, Cushman WC, Massie BM, Freis ED, Kochar MS, Hamburger RJ, Fye C, Lakshman R, Gottdiener J, Ramirez EA, Henderson WG (1993) Single-drug therapy for hypertension in men. A comparison of six antihypertensive agents with placebo. N Engl J Med 328:914–921

    Article  PubMed  CAS  Google Scholar 

  • Moser M (1999) National recommendations for the pharmacological treatment of hypertension. Should they be revised? Arch Intern Med 159:1403–1406

    Article  PubMed  CAS  Google Scholar 

  • MRC Working Party (1985) Medical Research Council trial of treatment of hypertension in older adults: principal results. Br Med J 304:405–412

    Google Scholar 

  • Prevention of stroke by antihypertensive drug treatment in older persons with isolated systolic hapertension (1991) Final results of the Systolic Hypertension in the Elderly Program (SHEP). JAMA 265:3255–3264

    Article  Google Scholar 

  • Oparil S (1993) Antihypertensive therapy — efficacy and quality of life. N Engl J Med 328: 959–961

    Article  PubMed  CAS  Google Scholar 

  • Peeters PHM, van Noord PAH, Hoes AW, Fracheboud J, Gimbrere CHF, Grobbee DE (2000) Hypertension and breast cancer risk in a 19-year follow-up study (the DOM cohort). J Hypertension 18:249–254

    Article  CAS  Google Scholar 

  • Preston RA, Materson BJ, Reda DJ, Williams DW, Hamburger RJ, Cushman WC, Anderson RJ for the Department of Veterans Affairs Cooperative Study Group on Antihypertensive Agents (1998). JAMA 280:1168–1172

    Article  PubMed  CAS  Google Scholar 

  • Preston RA, Materson BJ, Reda DJ, Williams DW (2000) Placebo-associated blood pressure response and adverse effects in the treatment of hypertension. Arch Intern Med 160: 1449–1454

    Article  PubMed  CAS  Google Scholar 

  • Saito T, Sugiyama Y, Inagaki Y (1992) Hemodynamic effects of antihypertensive agents: a comparison of diuretics, beta-blockers, calcium antagonists, and angiotensin converting enzyme inhibitors. Curr Therap Res 52:863–877

    Article  Google Scholar 

  • Schmieder RE, Rockstroh JK, Gatzka CD, Rüddel H, Schächinger H (1997) Discontinuation of antihypertensive therapy: prevalence of relapses and predictors of successful withdrawal in a hypertensive community. Cardiology 88:277–284

    Article  PubMed  CAS  Google Scholar 

  • The ALLHAT Officers and Coordinators for the ALLHAT Collaborative Research Group (2000) Major cardiovascular events in hypertensive patients randomized to doxazosin vs. chlorthalidone. The Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT). JAMA 283:1967–1975

    Article  Google Scholar 

  • The Joint National Committee on Detection, Evaluation, and Treatment of High Blood Pressure (1993) The Fifth Report of the Joint National Committee on Detection, Evaluation, and Treatment of High Blood Pressure (JNC V). Arch Intern Med 153:154–182

    Article  Google Scholar 

  • The Joint National Committee on Detection, Evaluation, and Treatment of High Blood Pressure (1997) The Sixth Report of the Joint National Committee on Detection, Evaluation, and Treatment of High Blood Pressure (JNC VI). Arch Intern Med 157:2413–2446

    Article  Google Scholar 

  • Tuomilehto J, Rastenyte D, Birkenhäger WH, Thiijs L, Antikainen R, Bulpitt CJ, Fletcher AE, Forette F, Goldhaber A, Palatini P, Sarti C, Fagard R for the Systolic Hypertension In Europe Trial Investigators (1999) Effects of calcium-channel blockade in older patients with diabetes and systolic hypertension. N Engl J Med 340:677–684

    Article  PubMed  CAS  Google Scholar 

  • Wang LL, Staessen JA, Gong L, Liu L, for the Systolic Hypertension in China (Syst-China) Collaborative Group (2000) Chinese trial on isolated systolic hypertension in the elderly. Arch Intern Med 160:211–220

    Article  PubMed  CAS  Google Scholar 

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© 2001 Steinkopff Verlag Darmstadt

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Stimpel, M. (2001). Medikamentöse Therapie der arteriellen Hypertonie. In: Arterielle Hypertonie. Steinkopff, Heidelberg. https://doi.org/10.1007/978-3-642-57617-1_21

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  • DOI: https://doi.org/10.1007/978-3-642-57617-1_21

  • Publisher Name: Steinkopff, Heidelberg

  • Print ISBN: 978-3-642-63309-6

  • Online ISBN: 978-3-642-57617-1

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