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Erkrankungen, die zu einer organischen psychischen Störung führen können

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Organische psychische Störungen

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Zusammenfassung

In diesem Kapitel werden Erkrankungen, die häufig zu einer organisch bedingten psychischen Störung führen können, ausführlich dargestellt. Dabei wird auch darauf eingegangen, ob und inwieweit psychische Symptome Frühsymptome oder gar die Erstmanifestation dieser Erkrankungen sein können. Da bei einer Reihe der in Frage kommenden Störungen verschiedene OPS auftreten können und daher die Differenzialdiagnose erschwert ist, sind in einer tabellarischen Übersicht (Tabelle 5.1) die am häufigsten vorkommenden zusammengestellt.

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Literatur

Literatur

  1. Aarsland D, Tandberg E, Larsen JP, Cummings JL (1996) Frequency of dementia in Parkinson’s disease. Arch Neurol 53:538–542

    Google Scholar 

  2. Akiyama H, Arai T, Kondo H, Tanno E, Haga C, Ikeda K (2000) Cell mediators of inflammation in the Alzheimer disease brain. Alzheimer Dis Assoc Disord 14 Suppl 1: 47–53

    Google Scholar 

  3. Ala TA, Yang KH, Sung JH, Frey WH (1997) Hallucinations and signs of parkinsonism help distinguish patients with dementia and cortical Lewy bodies from patients with Alzheimer’s disease at presentation: a clinicopathological study. J Neurol Nevrosurg Psychiatry 62:16–21

    CAS  Google Scholar 

  4. Albert ML, Feldman RG, Willis AL (1974) The “subcortical dementia” of progressive supranuclear palsy. J Neurol Neurosurg Psychiatry 37:121–130

    PubMed  CAS  Google Scholar 

  5. Alzheimer A (1907) Über eine eigenartige Erkrankung der Hirnrinde. Allg Z Psychiatrie 64:146–148

    Google Scholar 

  6. Alzheimer A (1911) Über eigenartige Krankheitsfälle des späteren Alters. Zbl ges Neurol Psychiat 4:356–385

    Google Scholar 

  7. American Psychiatric Association (1994) Diagnostic and statistical manual of mental disorders. Fourth edition (DSM-IV). American Psychiatric Press, Washington DC

    Google Scholar 

  8. Andersen J, Abro E, Gulmann N, Hjelmsted A, Pedersen HE (1980) Anti-depressive treatment in Parkinson’s disease: a controlled trial of the effect of nortriptyline in patients with Parkinson’s disease treated with L-DOPA. Acta Neurol Scand 62:210–219

    PubMed  CAS  Google Scholar 

  9. Andersen K, Launer LJ, Dewey ME, Letenneur L, Ott A, Copeland JR, Dartigues JF, Kragh-Sorensen P, Baldereschi M, Brayne C, Lobo A, Martinez-Lage JM, Stijnen T, Hofman A (1999) Gender differences in the incidence of AD and vascular dementia: The EURODEM Studies. EURODEM Incidence Research Group. Neurology 53:1992–1997

    PubMed  CAS  Google Scholar 

  10. Barger SW, Harmon AD (1997) Microglial activation by Alzheimer amyloid precursor protein and modulation by apolipoprotein E. Nature 388:878–881

    CAS  Google Scholar 

  11. Bayer TA, Wirths 0, Majtenyi K, Hartmann T, Multhaup G, Beyreuther K, Czech C (2001) Key factors in Alzheimer’s disease: beta-amyloid precursor protein processing, metabolism and intraneuronal transport. Brain Pathol 11:1–11

    PubMed  CAS  Google Scholar 

  12. Beffert U, Danik M, Krzywkowski P, Ramassamy C, Berrada F, Poirier J (1998) The neurobiology of apolipoproteins and their receptors in the CNS and Alzheimer’s disease. Brain Res - Brain Res Rev 27:119–142

    PubMed  CAS  Google Scholar 

  13. Bergman H, Chertkow H, Wolfson C, Stern J, Rush C, Whitehead V, Dixon R (1997) HM-PAO (CERETEC) SPECT brain scanning in the diagnosis of Alzheimer’s disease. J Am Geriatr Soc 45:15–20

    PubMed  CAS  Google Scholar 

  14. Beyreuther K (1997) Molekularbiologie der Alzheimer-Demenz. In: Förstl H (Hrsg) Lehrbuch der Gerontopsychiatrie. Enke, Stuttgart, S 31–43

    Google Scholar 

  15. Bickel H (1999) Epidemiologie der Demenzen. In: Förstl H, Bickel H, Kurz A (Hrsg) Alzheimer Demenz. Springer, Berlin, S 9–32

    Google Scholar 

  16. Bigl V (1997) Morpho-funktionelle Veränderungen des Gehirns im Alter and bei altersbegleitenden Hirnleistungsstörungen. In: Förstl H (Hrsg) Lehrbuch der Gerontopsychiatrie. Enke, Stuttgart, S 44–57

    Google Scholar 

  17. Birks J, Grimley Evans J, Iakovidou V V, Tsolaki M (2000) Rivastigmine for Alzheimer’s disease (Cochrane Review). Cochrane Database Syst Rev 2000; 4:CD001191

    Google Scholar 

  18. Birks JS, Melzer D, Beppu H (2000) Donepezil for mild and moderate Alzheimer’s disease (Cochrane Review). Cochrane Database Syst Rev 2000; 4:CD001190

    Google Scholar 

  19. Blacker D, Albert MS, Bassett SS, Go RC, Harrell LE, Folstein MF (1994) Reliability and validity of NINCDS-ADRDA criteria for Alzheimer’s disease. The National Institute of Mental Health Genetics Initiative. Arch Neurol 51:1198–1204

    PubMed  CAS  Google Scholar 

  20. Blessed G, Tomlinson BE, Roth M (1968) The association between quantitative measures of dementia and of senile change in the cerebral grey matter of elderly subjects. Br J Psychiatry 114:797–811

    PubMed  CAS  Google Scholar 

  21. Bondareff W, Mountjoy CQ, Roth M, Rossor MN, Iversen LL, Reynolds GP (1987) Age and histopathologic heterogeneity in Alzheimer’s disease. Arch Gen Psychiatry 44:412–417

    PubMed  CAS  Google Scholar 

  22. Boustany RMN, Kolodny EH (1989) The neuronal ceroid lipofuscinoses: a review. Rev Neurol 145:105–110

    PubMed  CAS  Google Scholar 

  23. Bowen DM, Davidson AN (1986) Biochemical studies of nerve cells and energy metabolism in Alzheimer’s disease. Brit Med Bull 42:75–80

    PubMed  CAS  Google Scholar 

  24. Bowler JV, Munoz DG, Merskey H, Hachinski V (1998) Fallacies in the pathological confirmation of the diagnosis of Alzheimer’s disease. J Neurol Neurosurg Psychiatry 64:18–24

    PubMed  CAS  Google Scholar 

  25. Braak H, Braak E (1994) Pathology of Alzheimer’s disease. In: Calne DB (ed) Neurodegenerative diseases. Saunders, Philadelphia, S 585–613

    Google Scholar 

  26. Brannan TS, Burger AA, Chaudhary MY (1980) Bilateral basal ganglia calcifications visualized on CT-scan. J Neurol Neurosurg Psychiatry 43:403–406

    PubMed  CAS  Google Scholar 

  27. Breteler MM, de Groot RR, van Romunde LK, Hofman A (1995) Risk of dementia in patients with Parkinson’s disease, epilepsy, and severe head trauma: a register-based follow-up study. Am J Epidemiol 142:1300–1305

    PubMed  CAS  Google Scholar 

  28. Brooks DJ (2000) Movement disorders: other hypokinetic disorders. In: Mazziotta JC, Toga AW, Frackowiak RSJ (eds) Brain Mapping. The disorders. Academic Press, San Diego, S 263–284

    Google Scholar 

  29. Brun A (1994) Pathology and pathophysiology of cerebrovascular dementia: pure subgroups ob obstructive and hypoperfusive etiology. Dementia 5:145–147

    PubMed  CAS  Google Scholar 

  30. Brun A, Englund E (1986) A white matter disorder in dementia of the Alzheimer type: A pathoanatomical study. Ann Neurol 19:253–262

    PubMed  CAS  Google Scholar 

  31. Bryant J, Clegg A, Nicholson T, McIntyre L, De Broe S, Gerard K, Waugh N (2001) Clinical and cost-effectiveness of donepezil, rivastigmine and galantamine for Alzheimer’s disease: a rapid and systematic review. Health Technol Assess 5:1–137

    PubMed  Google Scholar 

  32. Buch K, Riemenschneider M, Bartenstein P, Willoch F, Müller U, Schmolke M, Nolde T, Steinmann C, Guder WG, Kurz A (1998) Tau Protein: Ein potentieller Indikator zur Früherkennung der Alzheimer Krankheit. Nervenarzt 69:379–385

    PubMed  CAS  Google Scholar 

  33. Burns A, Jacoby R, Levy R (1990) Psychiatric phenomena in Alzheimer’s disease. I. Disorders of thought content. Br J Psychiatry 157:72–76

    PubMed  CAS  Google Scholar 

  34. Burns A, Jacoby R, Levy R (1990) Psychiatric phenomena in Alzheimer’s disease. III. disorders of mood. Br J Psychiatry 157:81–86

    PubMed  CAS  Google Scholar 

  35. Bryne JE (2000) The treatment of dementia with Lewy bodies. In: O’Brien J, Ames D, Burns A (eds) Dementia. 2“d ed. Arnold, London, S 729–734

    Google Scholar 

  36. Caine DB (ed) Neurodegenerative diseases. Saunders, Philadelphia

    Google Scholar 

  37. Cardoso F, Jankovic J (1994) Progressive supranuclear palsy. In: Calne DB (ed) Neurodegenerative diseases. Saunders, Philadelphia, S 769–786

    Google Scholar 

  38. Ceravolo R, Nuti A, Piccinni A, Dell’Agnello G, Bellini G, Gambaccini G, Dell’Osso L, Murri L, Bonuccelli U (2000) Paroxetine in Parkinson’s disease: effects on motor and depressive symptoms. Neurology 55:1216–1218

    PubMed  CAS  Google Scholar 

  39. Cercy SP, Byslsma FW (1997) Lewy bodies and progressive dementia: A critical review and meta-analysis. J Int Neuropsychol Soc 3:179–194

    PubMed  CAS  Google Scholar 

  40. Chua P, Chiu E (2000) Huntington’s disease. In: O’Brien J, Ames D, Burns A (eds) Dementia, 2“d edn. Arnold, London, S 827–843

    Google Scholar 

  41. Clark AW, Manz HJ, White III CL, Lehmann J, Miller D, Coyle JT (1986) Cortical degeneration with swollen chromatolytic neurons: its relationship to Pick’s disease. J Neuropathol Exp Neurol 45:268–284

    PubMed  CAS  Google Scholar 

  42. Constantinidis J, Richard J, Tissot R (1974) Pick’s disease. Histological and clinical correlations. Eur Neurol 11:208–217

    PubMed  CAS  Google Scholar 

  43. Cramer H (1988) Zur Neurochemie der Huntingtonschen Krankheit. In: Deuschl G, Oepen G, Wolff G (Hrsg) Die Huntingtonsche Krankheit, Springer, Berlin, S 128–139

    Google Scholar 

  44. Croisile B, Trillet M, Fondarai J, Laurent B, Mauguiere F, Billardon M (1993) Long-term and high-dose piracetam treatment of Alzheimer’s disease. Neurology 43:301–305

    PubMed  CAS  Google Scholar 

  45. Cummings JL (1992) Depression and Parkinson’s disease: a review. Am J Psychiatry 149:443–454

    PubMed  CAS  Google Scholar 

  46. De Deyn PP, Rabheru K, Rasmussen A, Bocksberger JP, Dautzenberg PL, Eriksson S, Lawlor BA (1999) A randomized trial of risperidone, placebo, and haloperidol for behavioral symptoms of dementia. Neurology 53:946–955

    PubMed  CAS  Google Scholar 

  47. DeKosky ST, Scheff SW (1990) Synapse loss in frontal cortex biopsies in Alzheimer’s disease: correlation with cognitive severity. Ann Neurol 27:457–464

    PubMed  CAS  Google Scholar 

  48. DeKosky ST, Harbaugh RE, Schmitt FA, Bakay RAE, Chui HC, Knopman DS, Reeder TM, Shetter AG, Senter HJ, Markesberry WR, Intraventricular Bethanecol Study Group (1992) Cortical biopsy in Alzheimer’s disease: diagnostic accuracy and neurochemical, neuropathological, and cognitive correlations. Ann Neurol 32:625–632

    PubMed  CAS  Google Scholar 

  49. Delacourte A (1990) General and dramatic glial reaction in Alzheimer brains. Neurology 40:33–37

    PubMed  CAS  Google Scholar 

  50. DeLong MR (2000) The basal ganglia. In: Kandel ER, Schwartz JH, Jessell TM (eds) Principles of neural science, 4` edn. McGraw-Hill, New York, pp 853–867

    Google Scholar 

  51. Del Ser T, McKeith I, Anand R, Cicin-Sain A, Ferrara R, Spiegel R (2000) Dementia with lewy bodies: findings from an international multicentre study. Int J Geriatr Psychiatry 15:1034–1045

    CAS  Google Scholar 

  52. Devanand DP, Jacobs DM, Tang MX, Del Castillo-Castaneda C, Sano M, Marder K, Bell K, Bylsma FW, Brandt J, Albert M, Stern Y (1997) The course of psychopathologic features in mild to moderate Alzheimer disease. Arch Gen Psychiatry 54:257–263

    PubMed  CAS  Google Scholar 

  53. Devanand DP, Marder K, Michaels KS, Sackeim HA, Bell K, Sullivan MA, Cooper TB, Pelton GH, Mayeux R (1998) A randomized, placebo-controlled dose-comparison trial of haloperidol for psychosis and disruptive behaviors in Alzheimer’s disease. Am J Psychiatry 155:1512–1520

    PubMed  CAS  Google Scholar 

  54. Dilling H, Mombour W, Schmidt MH (1994) Internationale Klassifikation psychischer Störungen. Forschungskriterien. Huber, Bern

    Google Scholar 

  55. Dilling H, Mombour W, Schmidt MH (2000) Klassifikation psychischer Krankheiten. Klinisch-diagnostische Leitlinien nach Kapitel V (F) der ICD-10, 3. Aufl. Huber, Bern

    Google Scholar 

  56. Di Maio L, Squitieri F, Napolitano G, Campanella G, Trofatter JA, Conneally PM (1993) Onset symptoms in 510 patients with Huntington’s disease. J Med Genet 30:289–292

    PubMed  CAS  Google Scholar 

  57. Dose M (2000) Chorea Huntington. In: Förstl H (Hrsg) Klinische Neuro-Psychiatrie. Thieme, Stuttgart, S 242–251

    Google Scholar 

  58. Eidelberg D, Edwards C, Mentis M, Dhawan V, Moeller JR (2000) Movement disorders: Parkinsons disease. In: Mazziotta JC, Toga AW, Frackowiak RSJ (eds) Brain Mapping. The disorders. Academic Press, San Diego, S 241–261

    Google Scholar 

  59. Elbaz A, Grigoletto F, Baldereschi M, Breteler MM, Manubens-Bertran JM, LopezPousa S, Dartigues JF, Alperovitch A, Tzourio C, Rocca WA (1999) Familial aggregation of Parkinson’s disease: a population-based case-control study in Europe. EUROPARKINSON Study Group. Neurology 52:1876–1882

    PubMed  CAS  Google Scholar 

  60. Englund E, Brun A, Alling A (1988) White matter changes in dementia of Alzheimer’s type. Brain 111:1425–1439

    PubMed  Google Scholar 

  61. Erkinjuntti T, Haltia M, Palo J, Sulkava R, Paetau A (1988) Accuracy of the clinical diagnosis of vascular dementia: a prospective clinical and post-mortem neuropathological study. J Neurol Neurosurg Psychiatry 51:1037–1044

    PubMed  CAS  Google Scholar 

  62. Fabbrini G, Barbanti P, Bonifati V, Colosimo C, Gasparini M, Vanacore N, Meco G (2001) Donepezil in the treatment of progressive supranuclear palsy. Acta Neurol Scand 103:123–125

    CAS  Google Scholar 

  63. Farlow MR, Hake A, Messina J, Hartman R, Veach J, Anand R (2001) Response of patients with Alzheimer disease to rivastigmine treatment is predicted by the rate of disease progression. Arch Neurol 58:417–422

    PubMed  CAS  Google Scholar 

  64. Fischhof PK, Saletu B, Rüther E, Litschauer G, Möslinger-Gehmayr R, Herrmann WM (1992) Therapeutic efficacy of pyritinol in patients with Senile Dementia of the Alzheimer Type (SDAT) and Multi-Infarct Dementia (MID). Neuropsychobiology 26:65–70

    PubMed  CAS  Google Scholar 

  65. Förstl H, Baldwin B (1994) Pick und die fokalen Hirnatrophie. Fortschr Neurol Psychiatr 62:345–355

    PubMed  Google Scholar 

  66. Förstl H (1999) The Lewy body variant of Alzheimer’s disease: clinical, patho-physiological and conceptual issues. Eur Arch Psychiatry Clin Neurosci 249, Suppl 3:64–67

    Google Scholar 

  67. Folstein M, Folstein S, McHugh PR (1975) Mini-Mental state: A practical for grading the cognitive state of patients for the clinican. J Psychiatric Res 12:189–192

    CAS  Google Scholar 

  68. Folstein SE (1989) Huntington’s disease: a disorder of families. John Hopkins University Press, Baltimore

    Google Scholar 

  69. Foroud T, Gray J, Ivashina J, Conneally PM (1999) Differences in duration of Huntington’s disease based on age at onset. J Neurol Neurosurg Psychiatry 66:52–56

    PubMed  CAS  Google Scholar 

  70. Frackowiak RSJ, Pozzilli C, Legg NJ, du Boulay GH, Marshall J, Lenzi GL, Jones T (1981) Regional cerebral, oxygen supply and utilization in dementia. A clinical and physiological study with oxygen-15 and positron tomography. Brain 104:753778

    Google Scholar 

  71. Frölich L (1997) Neurochemie - Glukosestoffwechsel - freie Sauerstoffradikale - Apolipoprotein E. In: Weis S, Weber G (Hrsg) Handbuch Morbus Alzheimer. Beltz PsychologieVerlagsUnion, Weinheim, S 411–434

    Google Scholar 

  72. Frölich L, Maurer K (1997) Klinische Untersuchung und Psychometrie. In: Förstl H (Hrsg) Lehrbuch der Gerontopsychiatrie. Enke, Stuttgart, S 84–94

    Google Scholar 

  73. Frölich L, Hampel H, Gorriz C, Schramm U (1999) Cholinerge Behandlungsstrategien. In: Förstl H, Bickel H, Kurz A (Hrsg) Alzheimer Demenz. Springer, Berlin, S 179–190

    Google Scholar 

  74. Fuchs A, Hehnke U, Erhart C, Schell C, Pramshohler B, Danninger B, Schautzer F (1993) Video rating analysis of effect of maprotiline in patients with dementia and depression. Pharmacopsychiatry 26:37–41

    PubMed  CAS  Google Scholar 

  75. Gearing M, Mirra SS, Hedreen JC, Sumi SM, Hansen LA, Heyman A (1996) The Consortium to Establish a Registry for Alzheimer’s Disease (CERAD). Part X. Neuropathology confirmation of the clinical diagnosis of Alzheimer’s disease. Neurology 45:461–466

    Google Scholar 

  76. George AE, de Leon MJ, Stylopoulos LA, Miller J, Kluger A, Smith G, Miller DC (1990) CT diagnostic features of Alzheimer disease: importance of the choroidal/ hippocampal fissure complex. Am J Neuroradiol 11:101–107

    PubMed  CAS  Google Scholar 

  77. Gertz HJ (1997) Nootropika. In: Förstl H (Hrsg) Lehrbuch der Gerontopsychiatrie. Enke, Stuttgart, S 163–171

    Google Scholar 

  78. Golbe LI, Davis PH, Schoenberg BS, Duvoisin RC (1988) Prevalence and the natural history of progressive supranuclear palsy. Neurology 38:1031–1034

    PubMed  CAS  Google Scholar 

  79. Gottfries CG (1989) Alzheimer’s disease - one, two, or several? J Neural Transm (P-D Sect) 1:22

    Google Scholar 

  80. Gottfries CG, Nyth AL (1991) Effect of citalopram, a selective 5-HT reuptake blocker, in emotionally disturbed patients with dementia. Ann NY Acad Sci 640:276–279

    PubMed  CAS  Google Scholar 

  81. Greenamyre JT, Shoulson I (1994) Huntington’s disease. In: Calne DB (ed) Neurodegenerative diseases. Saunders, Philadelphia, S 685–704

    Google Scholar 

  82. Gustafson L (1987) Frontal lobe degeneration of non-Alzheimer type. II. Clinical picture and differential diagnosis. Arch Gerontol Geriatr 6:209–233

    PubMed  CAS  Google Scholar 

  83. Haass G (1999) Molekulare Mechanismen der Alzheimer Erkrankung. In: Förstl H, Bickel H, Kurz A (Hrsg) Alzheimer Demenz. Springer, Berlin, S 55–66

    Google Scholar 

  84. Hampel H, Padberg F, Buch K, Unger J, Stübner S, Möller HJ (1999) Diagnose und Therapie der Demenz vom Alzheimer Typ. DMW 124:124–129

    CAS  Google Scholar 

  85. Harrington MG, MacPherson P, McIntosh WB, Allam BF, Bone I (1981) The significance of incidential finding of basal ganglia calcification on computed tomography. J Neurol Neurosurg Psychiatry 44:1168–1170

    PubMed  CAS  Google Scholar 

  86. Harvey RJ, Rossor MN, Skelton-Robinson M, Garralda E (1998) Young onset dementia: Epidemiology, clinical symptoms, family burden, supoort and outcome. National Hospital of Neurology and Neurosurgery. Dementia Group Publications. London

    Google Scholar 

  87. Haupt M, Janner H, Stierstorfer A, Kretschmar C (1998) Klinisches Erscheinungsbild und Stabilität nicht-kognitiver Symptome bei Patienten mit Alzheimer Krankheit. Fortschr Neurol Psychiat 66:233–240

    PubMed  CAS  Google Scholar 

  88. Hauser RA, Zesiewicz TA (1997) Sertraline for the treatment of depression in Parkinson’s disease. Mov Disord 12:756–759

    PubMed  CAS  Google Scholar 

  89. Hellenbrand W, Seidler A, Robra BP, Vieregge P, Oertel WH, Joerg J, Nischan P, Schneider E, Ulm G (1997) Smoking and Parkinson’s disease: a case-control study in Germany. Int J Epidemiol 26:328–339

    PubMed  CAS  Google Scholar 

  90. Hentschel F, Förstl H (1997) Neuroradiologische Diagnostik. In: Förstl H (Hrsg) Lehrbuch der Gerontopsychiatrie. Enke, Stuttgart, S 95–107

    Google Scholar 

  91. Herholz K (1995) FDG PET and differential diagnosis of dementia. Alzheimer Dis Assoc Disord 9:6–16

    PubMed  CAS  Google Scholar 

  92. Herrschaft H (1992) Nootropika. Spezieller Teil. In: Riederer P, Laux G, Pöldinger W (Hrsg) Neuro-Psychopharamaka, Band 5. Springer, Berlin, S 189–324

    Google Scholar 

  93. Heun R (1997) Demenzen bei andernorts klassifizierten Erkrankungen. In: Förstl H (Hrsg) Lehrbuch der Gerontopsychiatrie. Enke, Stuttgart, S 331–344

    Google Scholar 

  94. Heun R, Papassotiropoulus A (1999) Genetik der Alzheimer Demenz. In: Förstl H, Bickel H, Kurz A (Hrsg) Alzheimer Demenz. Springer, Berlin, S 33–54

    Google Scholar 

  95. Heyman A, Fillenbaum GG, Welsh-Bohmer KA, Gearing M, Mirra SS, Mohs RC, Peterson BL, Pieper CF (1998) Cerebral infarcts in patients with autopsy-proven Alzheimer’s disease: CERAD, part XVIII. Consortium to Establish a Registry for Alzheimer’s Disease. Neurology 51:159–162

    PubMed  CAS  Google Scholar 

  96. Hodges J (2000) Pick’s disease: its relationship to progressive aphasia, semantic dementia and frontotemporal dementia. In: O’Brien J, Ames D, Burns A (eds) Dementia, 2“ edn. Arnold, London, pp 747–758

    Google Scholar 

  97. Holmes C, Fortenza O, Powell J, Lovestone S (1997) Do neuroleptic drugs hasten cognitive decline in dementia? BMJ 314:1411

    PubMed  CAS  Google Scholar 

  98. Hornykiewicz O, Kish SJ (1984) Neurochemical basis of dementia in Parkinson’s disease. Can J Neurol Sci 11:185–190

    PubMed  CAS  Google Scholar 

  99. Huber SJ, Shuttleworth EC, Christy JA, Chakeres DW, Curtin A, Paulson GW (1989) Magnetic resonance imaging in dementia of Parkinson’s disease. J Neurol Neurosurg Psychiatry 52:1221–1227

    PubMed  CAS  Google Scholar 

  100. Huber SJ, Chakeres DW, Paulson GW, Khanna R (1990) Magnetic resonance imaging in Parkinson’s disease. Arch Neurol 47:735–737

    PubMed  CAS  Google Scholar 

  101. Hulette C, Mirra S, Wilkinson W, Heyman A, Fillenbaum G, Clark C (1995) The Consortium to Establish a Registry for Alzheimer’s Disease (CERAD). Part IX. A prospective cliniconeuropathologic study of Parkinson’s features in Alzheimer’s disease. Neurology 45:1991–1995

    PubMed  CAS  Google Scholar 

  102. Huntington G (1872) On chorea. Med Surg Rep 26:320–321

    Google Scholar 

  103. Huntington’s disease collaberative research group (1993) A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington’s disease chromosomes. Cell 72:971–983

    Google Scholar 

  104. Hutchinson M, Raff U (1999) Parkinson’s disease: a novel MRI method for determining structural changes in the substantia nigra. J Neurol Neurosurg Psychiatry 67:815–818

    PubMed  CAS  Google Scholar 

  105. Ihl R, Dierks T, Martin E-M, Frölich L, Maurer K (1992) Die Bedeutung des EEG bei der Früh-und Differentialdiagnose der Demenz vom Alzheimer Typ. Fortschr Neurol Psychiatr 60:451–459

    PubMed  CAS  Google Scholar 

  106. Ihl R (1999) Aktueller Stand der Diagnostik-und Therapieleitlinien. In: Müller WE (Hrsg) Dementielle Erkrankungen: Erkennen und behandeln. LinguaMed Verlag, Neu-Isenburg, S 103–124

    Google Scholar 

  107. Ince PG, McArthur FK, Bjertness E, Torvik A, Candy JM, Edwardson JA (1995) Neuropathological diagnoses in elderly patients in Oslo: Alzheimer’s disease, Lewy body disease, vascular lesions. Dementia 6:162–168

    PubMed  CAS  Google Scholar 

  108. Ince P, Perry R, Perry E (2000) Pathology of dementia with Lewy bodies. In: O’Brien J, Ames D, Burns A (eds) Dementia, 2nd edn. Arnold, London, pp 701–717

    Google Scholar 

  109. Iqbal K, Alonso AC, Gong CX, Khatoon S, Pei JJ, Wang JZ, Grundke-Iqbal I (1998) Mechanisms of neurofibrillary degeneration and the formation of neurofibrillary tangles. J Neural Transm Suppl 53:169–180

    PubMed  CAS  Google Scholar 

  110. Jackson M, Lowe J (1996) The new neuropathology of degenerative frontotemporal dementias. Acta Neuropathol 91:127–134

    PubMed  CAS  Google Scholar 

  111. Jacob H, Kawagoe T (1984) Klinische Neuropathologie des Parkinson-SyndromsProteintyp und Dopamintyp der Demelaninisierung. In: Fischer PA (Hrsg) Parkinson plus, Springer, Berlin, S 18–31

    Google Scholar 

  112. Jagust WJ, Budinger TF, Reed BR (1987) The diagnosis of dementia with single photon emission computed tomography. Arch Neurol 44:258–262

    PubMed  CAS  Google Scholar 

  113. Jakob H (1979) Die Picksche Krankheit. Springer, Berlin

    Google Scholar 

  114. Jellinger KA (1998) The neuropathological diagnosis of Alzheimer’s disease. J Neural Trans 53:97–118

    CAS  Google Scholar 

  115. Johnson KA, Jones K, Holman BL, Becker JA, Spiers PA, Satlin A, Albert MS (1998) Preclinical prediction of Alzheimer’s disease using SPECT. Neurology 50:1563–1571

    PubMed  CAS  Google Scholar 

  116. Johnstone M, Gearing AJ, Miller KM (1999) A central role for astrocytes in the inflammatory response to beta-amyloid; chemokines, cytokines and reactive oxygen species are produced. J Neuroimmunol 93:182–193

    PubMed  CAS  Google Scholar 

  117. Katz IR, Jeste DV, Mintzer JE, Clyde C, Napolitano J, Brecher M (1999) Comparison of risperidone and placebo for psychosis and behavioral disturbances associated with dementia: a randomized, double-blind trial. Risperidone Study Group. J Clin Psychiatry 60:107–115

    PubMed  CAS  Google Scholar 

  118. Katzman R, Terry R, DeTeresa R, Brown T, Davies P, Fuld P, Renbing X, Peck A (1988) Clinical, pathological, and neurochemical changes in dementia: a subgroup with perserved mental status and numerous neocortical plaques. Ann Neurol 23:138–144

    PubMed  CAS  Google Scholar 

  119. Koponen H, Stenbäck U, Mattila E, Soininen H, Reinikainen K, Riekkinen PJ (1989) Delirium among elderly persons admitted to a psychiatric hospital: clinical course during the acute stage and one-year follow-up. Acta Psychiatr Scand 79:579–585

    PubMed  CAS  Google Scholar 

  120. Kornhuber J, Gundacker I, Maler M, Otto M, Wiltfang J (1999) Neurotransmitterveränderungen bei der Alzheimer Demenz. In: Förstl H, Bickel H, Kurz A (Hrsg) Alzheimer Demenz. Springer, Berlin, S 33–54

    Google Scholar 

  121. Kosunen O, Soininen H, Paljarvi L, Heinonen O, Talasniemi S, Riekkinen PJ Sr (1996) Diagnostic accuracy of Alzheimer’s disease: a neuropathological study. Acta Neuropathol 91:185–193

    PubMed  CAS  Google Scholar 

  122. Kuhl DE, Minoshima S, Frey KA, Foster NL, Kilbourn MR, Koeppe RA (2000) Limited donepezil inhibition of acetylcholinesterase measured with positron emission tomography in living Alzheimer cerebral cortex. Ann Neurol 48:391–395

    PubMed  CAS  Google Scholar 

  123. Laitinen L (1969) Desipramine in treatment of Parkinson’s disease. Acta Neurol Scand 45:109–113

    PubMed  CAS  Google Scholar 

  124. Lang C (1994) Demenzen: Diagnose und Differentialdiagnose. Chapman & Hall, Weinheim

    Google Scholar 

  125. Lang C, Huk W, Taghavy A (1987) Zur klinischen Bedeutung bilateral-symmetrischer intrazerebraler Verkalkungen. Akt Neurol 14:91–98

    CAS  Google Scholar 

  126. Langston JW, Ballard P, Tetrud JW, Irwin I (1983) Chronic Parkinsonism in humans due to a product of mepredine-analog synthesis. Science 219:979–980

    PubMed  CAS  Google Scholar 

  127. Launer LJ, Andersen K, Dewey ME, Letenneur L, Ott A, Amaducci LA, Brayne C, Copeland JR, Dartigues JF, Kragh-Sorensen P, Lobo A, Martinez-Lage JM, Stijnen T, Hofman A (1999) Rates and risk factors for dementia and Alzheimer’s disease: results from EURODEM pooled analyses. EURODEM Incidence Research Group and Work Groups. European Studies of Dementia. Neurology 52:78–84

    PubMed  CAS  Google Scholar 

  128. Lautenschlager N, Kurz A, Müller U (1999) Erbliche Ursachen and Risikofaktoren der Alzheimer Krankheit. Nervenarzt 70:195–205

    PubMed  CAS  Google Scholar 

  129. Le Bars PL, Katz MM, Berman N, Itil TM, Freedman AM, Schatzberg AF (1997). A placebo-controlled, double-blind, randomized trial of an extract of Ginkgo biloba for dementia. North American EGb Study Group. JAMA 278:1327–1332

    PubMed  CAS  Google Scholar 

  130. Levy R, Förstl H, Müller WE (1997) Neurotransmitter-Substitution. In: Förstl H (Hrsg) Lehrbuch der Gerontopsychiatrie. Enke, Stuttgart, S 152–162

    Google Scholar 

  131. LeWitt PA, Brewer GJ (1994) Wilson’s disease (progressive hepatolenticular degeneration). In: Calne DB (ed) Neurodegenerative diseases. Saunders, Philadelphia, pp 667–683

    Google Scholar 

  132. Lewy FH (1912) Paralysis agitans. I. pathologische Anatomie. In: Lewandowsky M (Hrsg) Handbuch der Neurologie. Vol 3. Springer, Berlin, S 920–933

    Google Scholar 

  133. Lyetsos CG, Sheppard JM, Steele CD, Kopunek S, Steinberg M, Baker AS, Brandt J, Rabins PV (2000) Randomized placebo-controlled, double-blind clinical trial of sertaline in the treatment of depression complicating Alzheimer’s disease: initial results from the Depression in Alzheimer’s disease study. Am J Psychiatry 157:1686–1689

    Google Scholar 

  134. Magai C, Kennedy G, Cohen CI, Gomberg D (2000) A controlled clinical trial of sertaline in the treatment of depression in nursing home patients with late-stage Alzheimer’s disease. Am J Geriatr Psychiatry 8:66–74

    PubMed  CAS  Google Scholar 

  135. Maher ER, Lees AJ (1986) The clinical features and the natural history of the Steele-Richardson-Olszewski syndrome (progressive supranuclear palsy) Neurology 36:1005–1008

    PubMed  CAS  Google Scholar 

  136. Mann DMA (2000) The neuropathology and molecular genetics of frontotemporal dementia. In: O’Brien J, Ames D, Burns A (eds) Dementia, 2nd edn. Arnold, London, pp 759–768

    Google Scholar 

  137. Mann DMA, Yates PO, Marcyniuk B (1987) Dopaminergic neurotransmitter systems in Alzheimer’s disease and Down’s syndrome at middle age. J Neurol Neurosurg Psychiatry 50:341–344

    PubMed  CAS  Google Scholar 

  138. Marder K, Tang MX, Cote L, Stern Y, Mayeux R (1995) The frequency and associated risk factors for dementia in patients with Parkinson’s disease: Arch Neurol 52:695–701

    PubMed  CAS  Google Scholar 

  139. Marder K, Tang MX, Alfaro B, Mejia H, Cote L, Jacobs D, Stern Y, Sano M, Mayeux R (1998) Postmenopausal estrogen use and Parkinson’s disease with and without dementia. Neurology 50:1141–1143

    PubMed  CAS  Google Scholar 

  140. Marder K, Zhao H, Myers RH, Cudkowicz M, Kayson E, Kieburtz K, Orme C, Paulsen J, Penney JB, Siemers E, Shoulson I (2000) Rate of functional decline in Huntington’s disease. Huntington Study Group. Neurology 54:452–458

    PubMed  CAS  Google Scholar 

  141. Marsden CD (1982) Basal ganglia disease. Lancet ii:1141–1147

    Google Scholar 

  142. Martin JB, Gusella JF (1986) Huntington’s disease. Pathogenesis and management. N Engl J Med 315:1267–1276

    PubMed  CAS  Google Scholar 

  143. Marttila RJ (1983) Diagnosis and epidemiology of Parkinson’s disease. Acta Neu-rol. Scand. Suppl 95:9–17

    CAS  Google Scholar 

  144. Maurer K, Volk S, Gerbaldo H (1997) Auguste D and Alzheimer’s disease. Lancet 349:1546–1549

    PubMed  CAS  Google Scholar 

  145. Maurer K, Ihl R, Dierks T, Frölich L (1997) Clinical efficacy of Ginkgo biloba special extract EGb 761 in dementia of the Alzheimer type. J Psychiatr Res 31:645–655

    PubMed  CAS  Google Scholar 

  146. Mayer W, Henn R (1997) In: Förstl H (Hrsg) Lehrbuch der Gerontopsychiatrie. Enke, Stuttgart, S 16–30

    Google Scholar 

  147. Mayeux R, Denaro J, Hemenegildo N, Marder K, Tang MX, Cote LJ, Stern Y (1992) A population-based investigation of Parkinson’s disease with and without dementia. Relationship to age and gender. Arch Neurol 49:492–497

    PubMed  CAS  Google Scholar 

  148. Mayeux R, Saunders AM, Shea S, Mirra S, Evans D, Roses AD, Hyman BT, Crain B, Tang MX, Phelps CH (1998) Utility of the apolipoprotein E genotype in the diagnosis of Alzheimer’s disease. N Engl J Med 338:506–511

    CAS  Google Scholar 

  149. McKeith I (2000) Dementia with Lew~y bodies: a clinical overview. In: O’Brien J, Ames D, Burns A (eds) Dementia, 2edn. Arnold, London, pp 685–697

    Google Scholar 

  150. McKeith I, Fairbairn A, Perry R, Thompson P, Perry E (1992) Neuroleptics ensitivity in patients with senile dementia of Lewy body type. BMJ 305:673–678

    PubMed  CAS  Google Scholar 

  151. McKeith IG, Galasko D, Wilcock GK, Byrne EJ (1995) Lewy body dementia - diagnosis and treatment. Br J Psychiatry 167:709–717

    PubMed  CAS  Google Scholar 

  152. McKeith IG, Galasko D, Kosaka K, Perry EK, Dickson DW, Hansen LA, Salmon DP, Lowe J, Mirra SS, Byrne EJ, Lennox G, Quinn NP, Edwardson JA, Ince PG, Bergeron C, Burns A, Miller BL, Lovestone S, Collerton D, Jansen EN, Ballard C, de Vos RA, Wilcock GK, Jellinger KA, Perry RH (1996) Consensus guidelines for the clinical and pathologic diagnosis of dementia with Lewy bodies (DLB): report of the consortium on DLB international workshop. Neurology 47:1113–1124

    PubMed  CAS  Google Scholar 

  153. McKeith IG, Perry EK, Perry RH (1999) Report of the second dementia with Lewy body international workshop. Neurology 53:902–905

    PubMed  CAS  Google Scholar 

  154. McKeith I, Del Ser T, Spano P, Emre M, Wesnes K, Anand R, Cicin-Sain A, Ferrara R, Spiegel R (2000) Efficacy of rivastigmine in dementia with Lewy bodies: a randomised, double-blind, placebo-controlled international study. Lancet 356 (9247):2031–2036

    PubMed  CAS  Google Scholar 

  155. McKhann G, Drachman D, Folstein M, Katzman R, Price D, Stadlan EM (1984) Clinical diagnosis of Alzheimer’s disease: Report of the NINCDS-ADRDA work group under the auspices of Department of Health and human services task force on Alzheimer’s disease. Neurology 34:939–944

    PubMed  CAS  Google Scholar 

  156. McShane R, Keene J, Gedling K, Fairburn C, Jacoby R, Hope T (1997) Do neuroleptic drugs hasten cognitive decline in dementia? Prospective study with necropsy follow up. BMJ 314:266–270

    PubMed  CAS  Google Scholar 

  157. Mirra SS (1997) Neuropathological assessment of Alzheimer’s disease: the experience of the Consortium to Establish a Registry for Alzheimer’s Disease. Int Psychogeriatrics 9, Suppl 1:263–268

    Google Scholar 

  158. Mohs RC, Rosen WG, Davis KL (1983) The Alzheimer’s disease assessment scale: an instrment for assessing treatment efficiacy. Psychopharmol Bull 19:448–450

    CAS  Google Scholar 

  159. Morris JC, Mohs R, Roger H, Fillenbaum G, Heyman A (1988) CERAD clinical and neuropsychological assessment of Alzheimer’s disease. Psychopharmacol Bull 24:641–651

    PubMed  CAS  Google Scholar 

  160. Mountjoy CQ (1986) Correlations between neuropathological and neurochemical changes. Br Med Bull 42:81–85

    Google Scholar 

  161. Müller WE (1999) Antidementiva: Pharmakologische and therapeutische Bewertung. In: Müller WE (Hrsg) Dementielle Erkrankungen: Erkennen and Behandeln. LinguaMed Verlag, Neu-Isenburg, S 63–86

    Google Scholar 

  162. Munoz-Garcia D, Ludwin SK (1984) Classic and generalized variants of Pick’s disease: A clinicopathological, ultrastructural, and immunocytochemical comparative study. Ann Neurol 16:467–480

    PubMed  CAS  Google Scholar 

  163. Nagy Z, Esiri MM, Jobst KA, Morris JH, King EM, McDonald B, Litchfield S, Smith A, Barnetson L, Smith AD (1995) Relative roles of plaques and tangles in the dementia of Alzheimer’s disease: correlations using three sets of neuropathological criteria. Dementia 6:21–31

    PubMed  CAS  Google Scholar 

  164. Neary D (2000) Frontotemporal dementia. In: O’Brien J, Ames D, Burns A (eds) Dementia, 2nd edn. Arnold, London, pp 737–746

    Google Scholar 

  165. Neary D, Snowdon JS, Mann DMA, Bowen DM, Sims NR, Northen B, Yates PO, Davison AN (1986) Alzheimer’s disease: a correlative study. J Neurol, Neurosurg, Psychiat 49:229–237

    CAS  Google Scholar 

  166. Neary D, Snowdon JS, Northen B, Goulding P (1988) Dementia of frontal lobe type. J Neurol Neurosurg Psychiat 51:351–361

    Google Scholar 

  167. Neary D, Snowden JS, Gustafson L, Passant U, Stuss D, Black S, Freedman M, Kertesz A, Robert PH, Albert M, Boone K, Miller BL, Cummings J, Benson DF (1998) Frontotemporal lobar degeneration: a consensus on clinical diagnostic criteria. Neurology 51:1546–1554

    PubMed  CAS  Google Scholar 

  168. Nicholl DJ, Bennett P, Hiller L, Bonifati V, Vanacore N, Fabbrini G, Marconi R, Colosimo C, Lamberti P, Stocchi F, Bonuccelli U, Vieregge P, Ramsden DB, Meco G, Williams AC (1999) A study of five candidate genes in Parkinson’s disease and related neurodegenerative disorders. European Study Group on Atypical Parkinsonism. Neurology 53:1415–1421

    PubMed  CAS  Google Scholar 

  169. O’Connor DW, Politt PA, Hyde JB, Fellows JL, Miller ND, Roth M (1990) A follow-up study of dementia diagnosed in the community using the Cambridge mental disorders of the elderly examination. Acta Psychiat Scand 81:78–82

    PubMed  Google Scholar 

  170. Olichney JM, Galasko D, Salmon DP, Hofstetter CR, Hansen LA, Katzman R, Thal LJ (1998) Cognitive decline is faster in Lewy body variant than in Alzheimer’s disease. Neurology 51:351–357

    PubMed  CAS  Google Scholar 

  171. Parkinson J (1817) An essay on the shaking palsy. Sherwood, Nealy & Jones, London

    Google Scholar 

  172. Parkinson Study Group (1999) Low-dose clozapine for the treatment of drug-induced psychosis in Parkinson’s disease. N Engl J Med 340:757–763

    Google Scholar 

  173. Perry RH, Irving D, Blessed G, Fairbairn A, Perry EK (1990) Senile dementia of Lewy body type. A clinically and neuropathologically distinct form of Lewy body dementia in the elderly. J Neurol Sci 95:119–139

    PubMed  CAS  Google Scholar 

  174. Petracca G, Teson A, Chemerinski E, Leiguarda R, Starkstein SE (1996) A double-blind placebo-controlled study of clomipramine in depressed patients with Alzheimer’s disease. J Neuropsychiatry Clin Neurosci 8:270–275

    PubMed  CAS  Google Scholar 

  175. Pick A (1892) Über die Beziehungen der senilen Hirnatrophie zur Aphasie. Prager Med Wschr 17:165–167

    Google Scholar 

  176. Poewe WH, Wenning GK (1998) The natural history of Parkinson’s disease. Ann Neurol 44 Suppl 1:S1–9

    Google Scholar 

  177. Przuntek H, Hoffmann E (1987) Epidemiologische Untersuchung zum Morbus Wilson in der Bundesrepublik Deutschland. Nervenarzt 58:150–157

    PubMed  CAS  Google Scholar 

  178. Quinn NP, Rossor MN, Marsden CD (1986) Dementia and Parkinson’s disease - Pathological and neurochemical considerations. Brit Med Bull 42:86–90

    PubMed  CAS  Google Scholar 

  179. Rae-Grant A, Blume W, Lau C, Hachinski VC, Fisman M, Merskey H (1987) The electroencephalogramm in Alzheimer-type dementia. Arch Neurol 44:50–54

    PubMed  CAS  Google Scholar 

  180. Rajput AH (1984) Epidemiology of Parkinson’s disease. Can J Neurol Sci 11:156159

    Google Scholar 

  181. Ransmyr G, Wenning GK, Seppi K, Jellinger K, Poewe W (2000) Demenz mit Lewy Körperchen. Nervenarzt 71:929–935

    Google Scholar 

  182. Raskind MA, Peskind ER, Wessel T, Yuan W (2000) Galantamine in AD: A 6-month randomized, placebo-controlled trial with a 6-month extension. The Galantamine USA-1 Study Group. Neurology 54:2261–2268

    PubMed  CAS  Google Scholar 

  183. Reifler BV, Teri L, Raskind M, Veith R, Barnes R, White E, McLean P (1989) Double-blind trial of imipramine in Alzheimer’s disease patients with and without depression. Am J Psychiatry 146:45–49

    PubMed  CAS  Google Scholar 

  184. Riess O, Kruger R (1999) Parkinson’s disease - a multifactorial neurodegenerative disorder. Neural Transm Suppl 56:113–125

    CAS  Google Scholar 

  185. Rinne JO, Paljärvi L, Rinne UK (1987) Neuronal size and density in the nucleus basalis of Meynert in Alzheimer’s disease. J Neurol Sci 79:67–76

    PubMed  CAS  Google Scholar 

  186. Roos RA, Hermans J, Vegter-van der Vlis M, van Ommen GJ, Bruyn GW (1993) Duration of illness in Huntington’s disease is not related to age at onset. J Neu-rol Neurosurg Psychiatry 56:98–100

    PubMed  CAS  Google Scholar 

  187. Rosenquist K, Tariot P, Loy R (2000) Treatments for behavioral and psychological symptoms in Alzheimer’s disease and other dementias. In: O’Brien J, Ames D, Burns A (eds) Dementia, 2d edn. Arnold, London, pp 571–602

    Google Scholar 

  188. Sachs C, Ericson K, Erasmie U, Bergström M (1979) Incidence of basal ganglia calcifications on computed tomography. JCAT 3:339–344

    CAS  Google Scholar 

  189. Saletu B, Paulus E, Linzmayer L, Anderer P, Semlitsch HV, Grunberger J, Wicke L, Neuhold A, Podreka I (1995) Nicergoline in senile dementia of Alzheimer type and multi-infarct dementia: a double-blind, placebo-controlled, clinical and EEG/ERP mapping study. Psychopharmacology 117:385–395

    PubMed  CAS  Google Scholar 

  190. Sano M, Ernesto C, Thomas RG, Klauber MR, Schafer K, Grundman M, Woodbury P, Growdon J, Cotman CW, Pfeiffer E, Schneider LS, Thal LJ (1997) A controlled trial of selegiline, alpha-tocopherol, or both as treatment for Alzheimer’s disease. The Alzheimer’s Disease Cooperative Study. N Engl J Med 336:1216–1222

    Google Scholar 

  191. Saß H, Wittchen H-U, Zaudig M (Hrsg) (2000) Diagnostisches and statistisches Manual psychischer Störungen, DSM-IV, 3. Aufl. Hogrefe, Göttingen

    Google Scholar 

  192. Schmidt R, Fazekas F (1997) Klinische Bedeutung and neuropathologische Basis der `Leuko-Araiose’. In: Förstl H (Hrsg) Lehrbuch der Gerontopsychiatrie. Enke, Stuttgart, S 108–116

    Google Scholar 

  193. Schneider E, Becker H, Fischer PA, Grau H, Jacobi P, Brinkmann R (1979) The course of brain atrophy in Parkinson’s disease. Arch Psychiatr Nervenkr 227:8995

    Google Scholar 

  194. Schneider E, Fischer P-A, Jacobi P, Grotz A (1984) Exogene Psychosen beim Parkinsonsyndrom. Häufigkeit and Entstehungsbedingungen. Fortschr Neurol Psychiatr 52:207–214

    PubMed  CAS  Google Scholar 

  195. Schneider E (1991) Diagnostik and Therapie des Morbus Parkinson. de Gruyter, Berlin

    Google Scholar 

  196. Small GW, Rabins PV, Barry PP, Buckholtz NS, DeKosky ST, Ferris SH, Finkel SI, Gwyther LP, Khachaturian ZS, Lebowitz BD, McRae TD, Morris JC, Oakley F, Schneider LS, Streim JE, Sunderland T, Teri LA, Tune LE (1998) Diagnosis and treatment of Alzheimer disease and related disorders. Consensus statement of the American Association for Geriatric Psychiatry, the Alzheimer’s Association, and the American Geriatrics Society. JAMA 278:1363–1371

    Google Scholar 

  197. Spillantini MG, Bird TD, Ghetti B (1998) Frontotemporal dementia and parkinsonism linked to chromosome 17: a new group of tautopathies. Brain Pathol 8: 387–402

    PubMed  CAS  Google Scholar 

  198. Steele JC, Richardson JC, Olszewski J (1964) Progressive supranuclear palsy. A heterogeneous degeneration involving the brain stem, basal ganglia and cerebellum with vertical gaze and pseudobulbar palsy, nuchal dystonia and dementia. Arch Neurol 2:473–486

    Google Scholar 

  199. Stoppe G, Brandt CA, Staedt JH (1999) Behavioural problems associated with dementia: the role of newer antipsychotics. Drugs Aging 14:41–54

    PubMed  CAS  Google Scholar 

  200. Street JS, Clark WS, Gannon KS, Cummings JL, Bymaster FP, Tamura RN, Mitan SJ, Kadam DL, Sanger TM, Feldman PD, Tollefson GD, Breier A (2000) Olanzapine treatment of psychotic and behavioral symptoms with Alzheimer disease in nursing care facilities: a double-blind, randomized, placebo-controlled trial. The HGEU Study Group. Arch Gen Psychiatry 57:968–976

    PubMed  CAS  Google Scholar 

  201. Taragano FE, Lyketsos CG, Mangone CA, Allegri RF, Comesana-Diaz E (1997) A double-blind, randomized, fixed-dose trial of fluoxetine vs. amitriptyline in the treatment of major depression complicating Alzheimer’s disease. Psychosomatics 38:246–252

    PubMed  CAS  Google Scholar 

  202. Tariot PN, Solomon PR, Morris JC, Kershaw P, Lilienfeld S, Ding C (2000) A 5-month, randomized, placebo-controlled trial of galantamine in AD. The Galantamine USA-10 Study Group. Neurology 54:2269–2276

    PubMed  CAS  Google Scholar 

  203. Taxer F, Haller R, König P (1986) Klinische Frühsymptome und CT-Befunde beim Fahr’schen Syndrom. Nervenarzt 57:583–588

    PubMed  CAS  Google Scholar 

  204. Tesei S, Antonini A, Canesi M, Zecchinelli A, Mariani CB, Pezzoli G (2000) Tolerability of paroxetine in Parkinson’s disease: a prospective study. Mov disord 15:986–989

    PubMed  CAS  Google Scholar 

  205. Terry RD, Peck A, De Teresa R, Schechter R, Horoupian DS (1981) Some morphometric aspects of the brain in senile dementia of the Alzheimer type. Ann Neurol 10:184–192

    PubMed  CAS  Google Scholar 

  206. Thal LJ, Grundman M, Klauber MR (1988) Dementia: Characteristics of a referral population and factors associated with progression. Neurology 38:1083–1090

    PubMed  CAS  Google Scholar 

  207. Tuvanendran K, Low CH, Boey HK, Tan KP (1982) Basal ganglia calcification on computer tomographic scan: a clinical and radiological correlation. Acta Neurol Scand 66:309–315

    Google Scholar 

  208. Ulrich J, Probst A, West M (1986) The brain diseases causing senile dementia. J Neurol 233:118–122

    PubMed  CAS  Google Scholar 

  209. Velakoulis D, Lloyd J (2000) Parkinson’s disease and dementia: dpreva1ence and incidence. In: O’Brien J, Ames D, Burns A (eds) Dementia, 2’ edn. Arnold, London, pp 845–851

    Google Scholar 

  210. Vieregge P, Friedrich HJ, Rohl A, Ulm G, Heberlein I (1994) Zur multifaktoriellen Atiologie der idiopathischen Parkinson-Krankheit. Eine Fall-Kontroll-Studie. Nervenarzt 65:390–395

    PubMed  CAS  Google Scholar 

  211. Walker Z, Grace J, Overshot R, Satarasinghe S, Swan A, Katona CL, McKeith IG (1999) Olanzapine in dementia with Lewy bodies: a clinical study. Int J Geriatr Psychiatry 14:459–466

    PubMed  CAS  Google Scholar 

  212. Watt DC, Seller A (1993) A clinico-genetic study of psychiatric disorder in Huntington’s chorea. Psychol Med Monograph Suppl 23:1–46

    Google Scholar 

  213. Wetterling T (1989) Alzheimersche Erkrankung. Überblick über den aktuellen Stand der Forschung. Fortschr Neurol Psychiatr 57:1–13

    PubMed  CAS  Google Scholar 

  214. Wetterling T (1992) Neurotransmitter-Veränderungen bei der Demenz vom Alzheimer Typ. Nervenheilkunde 11:239–245

    Google Scholar 

  215. Wetterling T, Borgis K-J (1992) Klinisch-diagnostische Einordnung von Patienten mit Marklager-Hypodensitäten. Nervenheilkunde 11:294–298

    Google Scholar 

  216. Wetterling T (2001) Gerontopsychiatrie. Ein Leitfaden für Diagnostik und Therapie. Springer, Berlin

    Google Scholar 

  217. Wettstein A (2000) Cholinesterase inhibitors and Gingko extracts - are they comparable in the treatment of dementia? Comparison of published placebo-controlled efficacy studies of at least six months’ duration. Phytomedicine 6: 393–401

    PubMed  CAS  Google Scholar 

  218. Whitehouse PJ, Price DL, Struble RG, Clark AW, Coyle JT, Delon MR (1982) Alzheimer’s disease and senile dementia: loss of neurons in the basal forebrain. Science 215:1237–1239

    PubMed  CAS  Google Scholar 

  219. Whitehouse PJ, Martino AM, Marcus KA, Zweig RM, Singer HS, Price DL, Kellar KJ (1988) Reductions in acetylcholine and nicotine binding in several degenerative diseases. Arch Neurol 45:722–724

    PubMed  CAS  Google Scholar 

  220. Wilcock GK, Lilienfeld S, Gaens E (2000) Efficacy and safety of galantamine in patients with mild to moderate Alzheimer’s disease: multicentre randomised controlled trial. Galantamine International-1 Study Group. BMJ 321(7274):14451449

    Google Scholar 

  221. Winblad B, Poritis N (1999) Memantine in severe dementia: results of the M-best study. Int J Geriat Psychiat 14:135–146

    CAS  Google Scholar 

  222. World Health Organization (1993) International Classification of Diseases (ICD-10). Chapter V. Diagnostic guidelines. Genf

    Google Scholar 

  223. World Health Organization (1994) International Classification of Diseases (ICD-10). Chapter V. Research criteria. Genf

    Google Scholar 

  224. Yamamoto T, Hirano A (1985) Nucleus raphe dorsalis in Alzheimer’s disease: Neurofibrillary tangles and loss of large neurons. Ann Neurol 17:573–577

    PubMed  CAS  Google Scholar 

Literatur

  1. Absher JR, Toole JF (1996) Neurobehavioral features in cerebro vascular disease. In: Fogel BS, Schiffer RB, Rao SM (eds) Neuropsychiatry, Davis, Baltimore, S 895–912

    Google Scholar 

  2. Aharon-Peretz J, Kliot D, Tomer R (2000) Behavioral differences between white matter lacunar dementia and Alzheimer’s disease: a comparison on the neuropsychiatric inventory. Dement Geriatr Cogn Disord 11:294–298

    PubMed  CAS  Google Scholar 

  3. Albucher JF, Ferrieres J, Ruidavets JB, Guiraud-Chaumeil B, Perret BP, Chollet F (2000) Serum lipids in young patients with ischaemic stroke: a case-control study. J Neurol Neurosurg Psychiatry 69:29–33

    PubMed  CAS  Google Scholar 

  4. Alexopoulos GS, Meyers BS, Young RC, Campbell S, Silbersweig D, Charlson M (1997) Vascular depression’ hypothesis. Arch Gen Psychiatry 54:915–922

    PubMed  CAS  Google Scholar 

  5. Alexopoulos GS, Meyers BS, Young RC, Kakuma T, Silbersweig D, Chan son M (1997) Clinically defined vascular depression. Am. J Psychiatry 154:562–565

    PubMed  CAS  Google Scholar 

  6. Almkvist O, Wahlund L-O, Andersson-Lundman G, Basun H, Bäckman L (1992) White-matter hyperintensity and neuropsychological functions in dementia and healthy aging. Arch Neurol 49:626–632

    PubMed  CAS  Google Scholar 

  7. Almkvist O (1994) Neuropsychological deficits in vascular dementia in relation to Alzheimer’s disease: reviewing evidence for functional similarity or divergence. Dementia 5:203–209

    PubMed  CAS  Google Scholar 

  8. Alzheimer A (1898) Neuere Arbeiten über die Dementia senilis and die auf atheromatöser Gefäßerkrankung basierenden Gehirnerkrankungen. Monatsschr Psych Neurol 3:101–115

    Google Scholar 

  9. Alzheimer A (1902) Die Seelenstörungen auf arteriosklerotischer Grundlage. All Z Psychiatrie 59:695–711

    Google Scholar 

  10. Amar K, Lewis T, Wilcock G, Scott M, Bucks R (1995) The relationship between white matter low attenuation on brain CT and vascular risk factors: a memory clinic study. Age Ageing 24:411–415

    PubMed  CAS  Google Scholar 

  11. Andersen G, Vestergaard K, Lauritzen L (1994) Effective treatment of poststroke depression with the selective serotonin reuptake inhibitor citalpram. Stroke 25: 1099–1104

    PubMed  CAS  Google Scholar 

  12. Arboix A, Garcia-Eroles L, Massons J, Oliveres M, Targa C (2000) Lacunar infarcts in patients aged 85 years and older. Acta Neurol Scand 101:25–29

    PubMed  CAS  Google Scholar 

  13. Auperin A, Berr C, Bonithon-Kopp C, Touboul PJ, Ruelland I, Ducimetiere P, Alperovitch A (1996) Ultrasonographic assessment of carotid wall characteristics and cognitive functions in a community sample of 59- to 71-year-olds. The EVA Study Group. Stroke 27:1290–1295

    PubMed  CAS  Google Scholar 

  14. Awad IA, Johnson PC, Spetzler RF, Hodak JA (1986) Incidential subcortical lesions identified on magnetic resonance imaging in the elderly. II. Postmortem pathological correlations. Stroke 17:1090–1097

    PubMed  CAS  Google Scholar 

  15. Awada A, Omojola MF (1996) Leuko-araiosis and stroke: a case-control study. Acta Neurol Scand 94:415–418

    PubMed  CAS  Google Scholar 

  16. Babikian V, Ropper AH (1987) Binswanger’s disease: a review. Stroke 18:2–12

    PubMed  CAS  Google Scholar 

  17. Ballard C, McKeith I, O’Brien J, Kalaria R, Jaros E, Ince P, Perry R (2000) Neuropathological substrates of dementia and depression in vascular dementia, with a particular focus on cases with small infarct volumes. Dement Geriatr Cogn Disord 11:59–65

    PubMed  CAS  Google Scholar 

  18. Ballard C, Neill D, O’Brien J, McKeith IG, Ince P, Perry R (2000) Anxiety, depression and psychosis in vascular dementia: prevalence and associations. J Affect Disord 59:97–106

    PubMed  CAS  Google Scholar 

  19. Barba R, Martinez-Espinosa S, Rodriguez-Garcia E, Pondal M, Vivancos J, Del Ser T (2000) Poststroke dementia: clinical features and risk factors. Stroke 31:14941501

    Google Scholar 

  20. Bamford JM, Sanderock P, Jones L, Warlow CP (1987) The natural history of lacunar infarction: the Oxfordshire community stroke project. Stroke 18:545–551

    PubMed  CAS  Google Scholar 

  21. Bamford JM, Warlow CP (1988) Evolution and testing of the lacunar hypothesis. Stroke 19:1074–1082

    PubMed  CAS  Google Scholar 

  22. Barrett-Connor E, Khaw KT (1988) Diabetes mellitus: an independent risk factor for stroke? Am J Epidemiol 128:116–123

    PubMed  CAS  Google Scholar 

  23. Beckson M, Cummings JL (1991) Neuropsychiatric aspects of stroke. Int J Psychiatry Med 21:1–15

    PubMed  CAS  Google Scholar 

  24. Bennett DA, Wilson RS, Gilley DW, Fox JH (1990) Clinical diagnosis of Binswanger’s disease. J Neurol, Neurosurg, Psychiatry 53:961–965

    CAS  Google Scholar 

  25. Bent N, Rabbitt P, Metcalfe D (2000) Diabetes mellitus and the rate of cognitive ageing. Br J Clin Psychol 39:349–362

    PubMed  Google Scholar 

  26. Berger K, Kolominsky-Rabas P, Heuschmann P, Keil U (2000) Die Häufigkeit des Schlaganfalls in Deutschland. Prävalenzen, Inzidenzen and ihre Datenquellen. DMW125:21–25

    Google Scholar 

  27. Berwaerts J, Webster J (2000) Analysis of risk factors involved in oral-anticoagulant-related intracranial haemorrhages. QJM 93:513–521

    PubMed  CAS  Google Scholar 

  28. Bes A, Orgogozo JM, Poncet M, Rancurel G, Weber M, Bertholom N, Calvez R, Stehle B (1999) A 24-month, double-blind, placebo-controlled multicentre pilot study of the efficacy and safety of nicergoline 60 mg per day in elderly hypertensive patients with leukoaraiosis. Eur J Neurol 6:313–322

    PubMed  CAS  Google Scholar 

  29. Besson G, Hommel M, Perret J (2000) Risk factors for lacunar infarcts. Cerebrovasc Dis 10:387–390

    PubMed  CAS  Google Scholar 

  30. Binswanger O (1894) Die Abgrenzung der allgemeinen progressiven Paralyse. Berliner Klin Wschr 31:1103–1105, 1137–1139, 1180–1186

    Google Scholar 

  31. Blennow K, Wallin A, Uhlemann C, Gottfries CG (1991) White-matter lesions on CT in Alzheimer patients: relation to clinical symptomatology and vascular factors. Acta Neurol Scand 83:187–193

    PubMed  CAS  Google Scholar 

  32. Bogousslaysky J, Regli F (1986) Unilateral watershed cerebral infarcts. Neurology 36:373

    Google Scholar 

  33. Bogousslasky J, Regli F (1990) Anterior cerebral artery territory infarction in the Lausanne Stroke Registry. Arch Neurol 47:144–150

    Google Scholar 

  34. Bogousslaysky J (1992) The plurality of subcortical infarction. Stroke 23:629–631

    Google Scholar 

  35. Bogousslaysky J, Castillo V, Kumral E, Henriques I, Melle GV (1996) Stroke subtypes and hypertension. Primary hemorrhage vs infarction, large-vs small-artery disease. Arch Neurol 53:265–269

    Google Scholar 

  36. Bonarek M, Barberger-Gateau P, Letenneur L, Deschamps V, Iron A, Dubroca B, Dartigues JF (2000) Relationships between cholesterol, apolipoprotein E polymorphism and dementia: a cross-sectional analysis from the PAQUID study. Neuroepidemiology 19:141–148

    CAS  Google Scholar 

  37. Bone G, Ladurner G, Pichler M (1988) Klinische Prognosekriterien in der Rehabilitation von Insultpatienten. Rehabilitation 27:59–62

    PubMed  CAS  Google Scholar 

  38. Bornstein RA, Starling RC, Myerowitz PD, Haas GJ (1995) Neuropsychological function in patients with end-stage heart failure before and after cardiac transplantation. Acta Neurol Scand 91:260–265

    PubMed  CAS  Google Scholar 

  39. Bracco L, Campani D, Baratti E, Lippi A, Inzitari D, Pracucci G, Amaducci L (1993) Relation between MRI features and dementia in cerebrovascular disease patients with leukoaraiosis: a longitudinal study. J Neurol Sci 120:131–136

    PubMed  CAS  Google Scholar 

  40. Braffman BH, Zimmermann RA, Trojanowski JQ, Gonatas NK, Hickey WF, Schlaepfer WW (1988) Brain MR: pathologic correlation with gross and histopathology. 1. Lacunar infarction and Virchow-Robin spaces. Am J Radiol 151:551–558

    CAS  Google Scholar 

  41. Braffman BH, Zimmermann RA, Trojanowski JQ, Gonatas NK, Hickey WF, Schlaepfer WW (1988) Brain MR: pathologic correlation with gross and histopathology. 2. Hypertensive white-matter foci in the elderly. Am J Radiol 151:559–566

    CAS  Google Scholar 

  42. Brun A, Gustafson L (1988) Zerebrovaskuläre Erkrankungen. In: Kisker KP, Lauter H, Meyer J-E, Müller C, Strömgren E (Hrsg) Psychiatrie der Gegenwart 6, 3. Aufl. Springer, Berlin, S 253–295

    Google Scholar 

  43. Bulpitt CJ, Fletcher AE (1992) Cognitive function and angiotensin-converting enzyme inhibitors in comparison with other antihypertensive drugs. J Cardiovasc Pharmacol 19, Suppl 6:100–104

    Google Scholar 

  44. Cacciatore F, Abete P, Ferrara N, Calabrese C, Napoli C, Maggi S, Varricchio M, Rengo F (1998) Congestive heart failure and cognitive impairment in an older population. Osservatorio Geriatrico Campano Study Group. J Am Geriatr Soc 46:1343–1348

    PubMed  CAS  Google Scholar 

  45. Capizzano AA, Schuff N, Amend DL, Tanabe JL, Norman D, Maudsley AA, Jagust W, Chui HC, Fein G, Segal MR, Weiner MW (2000) Subcortical ischemic vascular dementia: assessment with quantitative MR imaging and 1H MR spectroscopy. Am J Neuroradiol 21:621–630

    PubMed  CAS  Google Scholar 

  46. Carson AJ, MacHale S, Allen K, Lawrie SM, Dennis M, House A, Sharpe M (2000) Depression after stroke and lesion location: a systematic review. Lancet 356 (9224):122–126

    PubMed  CAS  Google Scholar 

  47. Castillo CS, Schultz SK, Robinson RG (1995) Clinical correlates of early-onset and late-onset poststroke generalized anxiety. Am J Psychiatry 152:1174–1179

    PubMed  CAS  Google Scholar 

  48. Chimowitz MI, Estes ML, Furlan AJ, Awad IA (1992) Further observations on the pathology of subcortical lesions identified on magnetic resonance imaging. Arch Neurol 49:747–752

    PubMed  CAS  Google Scholar 

  49. Chui HC, Victoroff JI, Margolin D, Jagust W, Shankle R, Katzman R (1992) Criteria for the diagnosis of ischemic vascular dementia proposed by the State of California Alzheimer’s disease diagnostic and treatment centers. Neurology 42:473–480

    PubMed  CAS  Google Scholar 

  50. Chui HC, Mack W, Jackson JE, Mungas D, Reed BR, Tinklenberg J, Chang FL, Skinner K, Tasaki C, Jagust WJ (2000) Clinical criteria for the diagnosis of vascular dementia: a multicenter study of comparability and interrater reliability. Arch Neurol 57:191–196

    PubMed  CAS  Google Scholar 

  51. Cooper B, Bickel H (1987) Old people in hospital: a study of a psychiatric high-risk group. In: Angermeyer MC (ed) From social class to social stress. Springer, Berlin, pp 235–246

    Google Scholar 

  52. Cummings JL (1985) Organic delusions: phenomenology, anatomical correlational, and review. Br J Psychiatry 146:184–197

    PubMed  CAS  Google Scholar 

  53. Cummings JL, Miller B, Hill MA, Neshkes R (1987) Neuropsychiatric aspects of multi-infarct dementia and dementia of the Alzheimer type. Arch Neurol 44:389–393

    PubMed  CAS  Google Scholar 

  54. Cummings JL (1993) Frontal-subcortical circuits and human behavior. Arch Neu-rol 50:873–880

    Google Scholar 

  55. Dam M, Tonin P, DeBoni A, Pizzolato G, Casson S, Ermani M, Freo U, Prion L, Battisin L (1996) Effects of fluoxetine and maprotiline on functional recovery in post-stroke hemiplegic patients undergoing rehabilitation therapy. Stroke 27:1211–1214

    PubMed  CAS  Google Scholar 

  56. Damasio H (1983) A computed tomographic guide to the identification of cerebral territories. Arch Neurol 40:138–142

    PubMed  CAS  Google Scholar 

  57. De Groot JC, de Leeuw FE, Oudkerk M, Hofman A, Jolies J, Breteler MM (2000) Cerebral white matter lesions and depressive symptoms in elderly adults. Arch Gen Psychiatry 57:1071–1076

    PubMed  CAS  Google Scholar 

  58. De Leeuw F-E, de Groot JC, Achten E, Oudkerk M, Ramos LMP, Heijboer R, Hof-man A, Jolies J, van Gijn J, Breteler MMB (2001) Prevalence of cerebral white matter lesions in elderly people: a population based magnetic resonance imaging study. The Rotterdam Scan Study. J Neurol Neurosurg Psychiatry 70:9–14

    PubMed  CAS  Google Scholar 

  59. DePedro-Cuesta J, Widen-Holmqvist L, Bach-y-Rita P (1992) Evaluation of stroke rehabilitation controlled studies: a review. Acta Neurol Scand 86:433–439

    CAS  Google Scholar 

  60. Derouesne C, Poirier J (1999) Les lacunes cerebrales. Un debat toujours d’actualite. Rev Neurol (Paris) 155:823–831

    CAS  Google Scholar 

  61. Desmond DW, Moroney JT, Lynch T, Chan S, Chin SS, Mohr JP (1999) The natural history of CADASIL: a pooled analysis of previously published cases. Stroke 30:1230–1233

    PubMed  CAS  Google Scholar 

  62. Desmond DW, Moroney JT, Paik MC, Sano M, Mohr JP, Aboumatar S, Tseng CL, Chan S, Williams JB, Remien RH, Hauser WA, Stern Y (2000) Frequency and clinical determinants of dementia after ischemic stroke. Neurology 54:1124–1131

    PubMed  CAS  Google Scholar 

  63. Dilling H, Mombour W, Schmidt MH (1994) Klassifikation psychischer Krankheiten. Forschungskriterien nach Kapitel V (F) der ICD-10. Huber, Bern

    Google Scholar 

  64. Dilling H, Mombour W, Schmidt MH (2000) Klassifikation psychischer Krankheiten. Klinisch-diagnostische Leitlinien nach Kapitel V (F) der ICD-10, 3. Aufl. Huber, Bern

    Google Scholar 

  65. Donnan GA, Norrving B, Bamford JM, Bogousslaysky J (1993) Subcortical infarction: classification and terminology. Cerebrovasc Dis 3:248–251

    Google Scholar 

  66. Du X, McNamee R, Cruickshank K (2000) Stroke risk from multiple risk factors combined with hypertension: a primary care based case-control study in a defined population of northwest England. Ann Epidemiol 10:380–388

    PubMed  CAS  Google Scholar 

  67. Eiber R, Berlin I, Grimaldi A, Bisserbe JC (1997) Diabete insulinodependent et pathologie psychiatrique: revue generale clinique et epidemiologique. Encephale 23:351–357

    PubMed  CAS  Google Scholar 

  68. Eisenblätter D, Claßen E, Schädlich H, Heinemann L (1994) Häufigkeit und Prognose von Schlaganfallerkrankungen in der Bevölkerung Ostdeutschlands. Nervenarzt 65:95–100

    PubMed  Google Scholar 

  69. Elkind MS, Lin IF, Grayston JT, Sacco RL (2000) Chlamydia pneumoniae and the risk of first ischemic stroke: The Northern Manhattan Stroke Study. Stroke 31: 1521–1525

    PubMed  CAS  Google Scholar 

  70. Englund E, Brun A, Alling A (1988) White matter changes in dementia of Alzheimer’s type. Brain 111:1425–1439

    PubMed  Google Scholar 

  71. Eriksson S, Asplund K, Hagg E, Lithner F, Strand T, Wester PO (1987) Clinical profiles of cerebrovascular disorders in a population-based patient sample. J Chronic Dis 40:1025–1032

    PubMed  CAS  Google Scholar 

  72. Erkinjuntti T, Laaksonen R, Sulkava R, Syrjlinen R, Palo J (1986) Neuropsychological differentiation between normal aging, Alzheimer’s disease and vascular dementia. Acta Neurol Scand 74:393–403

    PubMed  CAS  Google Scholar 

  73. Erkinjuntti T, Ketonen L, Sulkava R, Sipponen J, Vuorialho M, Iivanainen M (1987) Do white matter changes on MRI and CT differentiate vascular dementia from Alzheimer’s disease. J Neurol, Neurosurg, Psychiatry 50:37–42

    CAS  Google Scholar 

  74. Erkinjuntti T, Haltia M, Palo J, Sulkava R, Paetau A (1988) Accuracy of the clinical diagnosis of vascular dementia: a prospective clinical and post-mortem neuropathological study. J Neurol Neurosurg Psychiatry 51:1037–1044

    PubMed  CAS  Google Scholar 

  75. Erkinjuntti T, Bowler JV, DeCarli CS, Fazekas F, Inzitari D, O’Brien JT, Pantoni L, Rockwood K, Scheltens P, Wahlund LO, Desmond DW (1999) Imaging of static brain lesions in vascular dementia: implications for clinical trials. Alzheimer Dis Assoc Disord 13 Suppl 3:S 81–90

    Google Scholar 

  76. Erkinjuntti T, Inzitari D, Pantoni L, Wallin A, Scheltens P, Rockwood K, Roman GC, Chui H, Desmond DW (2000) Research criteria for subcortical vascular dementia in clinical trials. J Neural Transm Suppl 59:23–30

    PubMed  CAS  Google Scholar 

  77. Evers S, Koch HG, Grotemeyer KH, Lange B, Deufel T, Ringelstein EB (1997) Features, symptoms, and neurophysiological findings in stroke associated with hyperhomocysteinemia. Arch Neurol 54:1276–1282

    PubMed  CAS  Google Scholar 

  78. Farina E, Magni E, Ambrosini F, Manfredini R, Binda A, Sina C, Mariani C (1997) Neuropsychological deficits in asymptomatic atrial fibrillation. Acta Neurol Scand 96:310–316

    PubMed  CAS  Google Scholar 

  79. Ferrucci L, Guralnik JM, Salive ME, Pahor M, Corti MC, Baroni A, Havlik RJ (1996) Cognitive impairment and risk of stroke in the older population. J Am Geriatr Soc 44:237–241

    PubMed  CAS  Google Scholar 

  80. Fisher CM (1965) Lacunes: Small, deep cerebral infarcts. Neurology 15:774–784

    PubMed  CAS  Google Scholar 

  81. Fisher CM (1969) The arterial lesions underlying lacunes. Acta Neuropathol 12:1–15

    Google Scholar 

  82. Fisher CM (1982) Lacunar strokes and infarcts: A review. Neurology 32:871–876

    PubMed  CAS  Google Scholar 

  83. Fisher CM (1989) Binswanger’s encephalopathy: a review. J Neurol 236:65–79

    PubMed  CAS  Google Scholar 

  84. Frank R, Fischer V, Kittner P, Jacobi P (1985) Krankheitsverarbeitung and Persönlichkeit: Zur psychotherapeutischen Beeinflussung von KrankheitsverleugnungsStrategien bei Schlaganfall-Patienten. Psychother Med Psychol 35:281–289

    CAS  Google Scholar 

  85. Fujishima M, Yao H, Terashi A, Tagawa K, Matsumoto M, Hara H, Akiguchi I, Suzuki K, Nishimaru K, Udaka F, Gyoten T, Takeuchi J, Hamada R, Yoshida Y, Ibayashi S (2000) Deep white matter lesions on MRI, and not silent brain infarcts are related to headache and dizziness of non-specific cause in non-stroke Japanese subjects. Intern Med 39:727–731

    PubMed  CAS  Google Scholar 

  86. Gale CR, Martyn CN, Cooper C (1996) Cognitive impairment and mortality in a cohort of elderly people. BMJ 312:608–611

    PubMed  CAS  Google Scholar 

  87. Garde E, Mortensen EL, Krabbe K, Rostrup E, Lrsson HB (2000) Relation between age-related decline in intelligence and cerebral white-matter hyperintensities in healthy octogenarians: a longitudinal study. Lancet 356:628–634

    PubMed  CAS  Google Scholar 

  88. George AE, de Leon MJ, Kalnin A, Rosner L, Goodgold A, Chase N (1986) Leucoencephalopathy in normal and pathologic ageing: 2. MRI of brain lucencies. Am J Neuroradiol 7:567–570

    PubMed  CAS  Google Scholar 

  89. Giles WH, Kittner SJ, Croft JB, Wozniak MA, Wityk RJ, Stern BJ, Sloan MA, Price TR, McCarter RJ, Macko RF, Johnson CJ, Feeser BR, Earley CJ, Buchholz DW, Stolley PD (1999) Distribution and correlates of elevated total homocyst(e)ine: the Stroke Prevention in Young Women Study. Ann Epidemiol 9:307–313

    PubMed  CAS  Google Scholar 

  90. Giroud M, Beuriat P, Vion P, D’Athis PH, Dusserre L, Dumas R (1989) Stroke in a French prospective population study. Neuroepidemiology 8:97–104

    PubMed  CAS  Google Scholar 

  91. Glahn J, Straeten V (1994) Pathogenese and klinischer Verlauf akuter ischämischer Insulte an einem kommunalen Schwerpunktkrankenhaus. Nervenarzt 65:101–108

    PubMed  CAS  Google Scholar 

  92. Gottfries CG, Blennow K, Karlsson I, Wallin A (1994) The neurochemistry of vascular dementia. Dementia 5:163–167

    PubMed  CAS  Google Scholar 

  93. Gregg EW, Yaffe K, Cauley JA, Rolka DB, Blackwell TL, Narayan KM, Cummings SR (2000) Is diabetes associated with cognitive impairment and cognitive decline among older women? Study of Osteoporotic Fractures Research Group. Arch Intern Med 160:174–180

    PubMed  CAS  Google Scholar 

  94. Hachinski VC, Lassen NA, Marshall J (1974) Multi-infarct dementia. A cause of mental deterioration in the elderly. Lancet ii:207–210

    Google Scholar 

  95. Hachinski VC, Potter P, Merskey H (1987) Leuko-Araiosis. Arch Neurol 44:21–23

    Google Scholar 

  96. Hagendorff A, Dettmers C, Jung W, Hummelgen M, Kolsch C, Hartmann A, Luderitz B, Pfeiffer D (2000) Herzschrittmacher-Therapie zur Optimierung der Hirndurchblutung. Eine Möglichkeit zur Prävention zerebrovaskulärer Erkrankungen? DMW 125:286–289

    CAS  Google Scholar 

  97. Hamilton M (1960) A rating scale for depression. J Neurol Neurosurg Psychiatry 23:56–62

    PubMed  CAS  Google Scholar 

  98. Harrington F, Saxby BK, McKeith IG, Wesnes K, Ford GA (2000) Cognitive performance in hypertensive and normotensive older subjects. Hypertension 36:1079–1082

    PubMed  CAS  Google Scholar 

  99. Hebert R, Lindsay J, Verreault R, Rockwood K, Hill G, Dubois MF (2000) Vascular dementia: incidence and risk factors in the Canadian study of health and aging. Stroke 31:1487–1493

    PubMed  CAS  Google Scholar 

  100. Heckbert SR, Longstreth WT Jr, Psaty BM, Murros KE, Smith NL, Newman AB, Williamson JD, Bernick C, Furberg CD (1997) The association of antihypertensive agents with MRI white matter findings and with Modified Mini-Mental State Examination in older adults. J Am Geriatr Soc 45:1423–1433

    PubMed  CAS  Google Scholar 

  101. Hennerici MG (1997) Vaskuläre Demenzen. In: Förstl H (Hrsg) Lehrbuch der Gerontopsychiatrie. Enke, Stuttgart, S 309–330

    Google Scholar 

  102. Herrmann M, Bartels C, Wallesch C-W (1993) Depression in acute and chronic aphasia: symptoms, pathoanatomical-clinical correlations and functional implications. J Neurol Neurosurg Psychiatry 56:672–678

    PubMed  CAS  Google Scholar 

  103. Hier DB, Foulkes MA, Swiontoniowski M, Sacco RL, Gorelick PB, Mohr JP, Price TR, Wolf PA (1991) Stroke recurrence within 2 years after ischemic infarction. Stroke 22:155–161

    PubMed  CAS  Google Scholar 

  104. Hijdra A, Verbeeten B Jr, Verhulst JA (1990) Relation of leukoaraiosis to lesion type in stroke patients. Stroke 21:890–894

    PubMed  CAS  Google Scholar 

  105. Hirono N, Kitagaki H, Kazui H, Hashimoto M, Mori E (2000) Impact of white matter changes on clinical manifestation of Alzheimer’s disease: A quantitative study. Stroke 31:2182–2128

    PubMed  CAS  Google Scholar 

  106. Horowitz DR, Tuhrim S, Weinberger JM, Rudolph SH (1992) Mechanisms in lacunar infarctions. Stroke 23:325–327

    PubMed  CAS  Google Scholar 

  107. Howard R, Trend P, Russell RWR (1987) Clinical features of ischemia in cerebral arterial border zones after periods of reduced cerebral blood flow. Arch Neurol 44:934–940

    PubMed  CAS  Google Scholar 

  108. Hüwel J, Weisner B, Kemmer H, Heyder J (1998) Depressive Verstimmung im Akutstadium nach erstmaligem ischämischen Hirninfarkt. Nervenarzt 69:330–334

    PubMed  Google Scholar 

  109. Hulette C, Nochlin D, McKeel D, Morris JC, Mirra SS, Sumi SM, Heyman A (1997) Clinical-neuropathologic findings in multi-infarct dementia: a report of six autopsied cases. Neurology 48:668–672

    PubMed  CAS  Google Scholar 

  110. Inzitari D, Diaz F, Fox A, Hachinski VC, Steingart A, Lau C, Donald A, Wade A, Mulic H, Merskey H (1987) Vascular risk factors and leuko-araisois. Arch Neurol 44:42–47

    PubMed  CAS  Google Scholar 

  111. Inzitari D, Eliasziw M, Gates P, Sharpe BL, Chan RK, Meldrum HE, Barnett HJ (2000) The causes and risk of stroke in patients with asymptomatic internal-carotid-artery stenosis. North American Symptomatic Carotid Endarterectomy Trial Collaborators. N Engl J Med 342:1693–1700

    PubMed  CAS  Google Scholar 

  112. Inzitari D, Romanelli M, Pantoni L (2000) Leukoaraiosis and cognitive impairment. In: O’Brien J, Ames D, Burns A (eds) Dementia, 2“a edn. Arnold, London, pp 635–653

    Google Scholar 

  113. Ishii N, Nishihara Y, Imamura T (1986) Why do frontal lobe symptoms predominate in vascular dementia with lacunes? Neurology 36:340–345

    PubMed  CAS  Google Scholar 

  114. Iwamoto T, Shimizu T, Ami M, Yoneda Y, Imamura T, Takasaki M (2000) Dementia and disability after initial cerebral thrombosis evaluated by MR1 and their clinical course[japanisch]. Nippon Ronen Igakkai Zasshi 37:162–169

    PubMed  CAS  Google Scholar 

  115. Jayakumar PN, Taly AB, Shanmugam V, Nagaraja D, Arya BYT (1989) Multi-infarct dementia: a computed tomographic study. Acta Neurol Scand 73:292–295

    Google Scholar 

  116. Jick H, Zornberg GL, Jick SS, Seshadri S, Drachman DA (2000) Statins and the risk of dementia. Lancet 356 (9242):1627–1631

    PubMed  CAS  Google Scholar 

  117. Jorgensen L, Torvik A (1969) Ischaemic cerebrovascular diseases in an autopsy series. Part 2. prevalence, location, pathogenesis and clinical course of cerebral infarcts. J Neurol Sci 9:285–320

    PubMed  CAS  Google Scholar 

  118. Jorgensen HS, Nakayama H, Raaschou HO, Olsen TS (1995) Intracerebral hemorrhage versus infarction: stroke severity, risk factors, and prognosis. Ann Neurol 38:45–50

    PubMed  CAS  Google Scholar 

  119. Jousilahti P, Rastenyte D, Tuomilehto J (2000) Serum gamma-glutamyl transfer-ase, self-reported alcohol drinking, and the risk of stroke. Stroke 31:1851–1855

    PubMed  CAS  Google Scholar 

  120. Juvela S, Porras M, Poussa K (2000) Natural history of unruptured intracranial aneurysms: probability of and risk factors for aneurysm rupture. J Neurosurg 93:379–387

    PubMed  CAS  Google Scholar 

  121. Kalra L, Dale P, Crome P (1993) Improving stroke rehabilitation. Stroke 24: 1462–1467

    PubMed  CAS  Google Scholar 

  122. Kalmijn S, Feskens EJ, Launer LJ, Stijnen T, Kromhout D (1995) Glucose intolerance, hyperinsulinaemia and cognitive function in a general population of elderly men. Diabetologia 38:1096–1102

    PubMed  CAS  Google Scholar 

  123. Kalmijn S, Feskens EJ, Launer LJ, Kromhout D (1997) Polyunsaturated fatty acids, antioxidants, and cognitive function in very old men. Am J Epidemiol 145:33–41

    PubMed  CAS  Google Scholar 

  124. Kalmijn S, Launer LJ, Lindemans J, Bots ML, Hofman A, Breteler MM (1999) Total homocysteine and cognitive decline in a community-based sample of elderly subjects: the Rotterdam Study. Am J Epidemiol 150:283–289

    PubMed  CAS  Google Scholar 

  125. Kalmijn S, Foley D, White L, Burchfiel CM, Curb JD, Petrovitch H, Ross GW, Havlik RJ, Launer LJ (2000) Metabolic cardiovascular syndrome and risk of dementia in japanese-american elderly men: the honolulu-asia aging study. Arterioscler Thromb Vasc Biol 20:2255–2260

    PubMed  CAS  Google Scholar 

  126. Kalmijn S, Kalmijn S (2000) Fatty acid intake and the risk of dementia and cognitive decline: a review of clinical and epidemiological studies. J Nutr Health Aging 4:202–207

    PubMed  CAS  Google Scholar 

  127. Kappelle LJ, Koudstaal PJ, van Gijn J, Ramos LMP, Keunen JEE (1988) Carotid angiography in patients with lacunar infarction. Stroke 19:1093–1096

    PubMed  CAS  Google Scholar 

  128. Kawamura J, Meyer JS, Ichijo M, Kobari M, Terayama Y, Weathers S (1993) Correlations of leuko-araiosis with cerebral atrophy and perfusion in elderly normal subjects and demented patients. J Neurol Neurosurg Psychiatry 56:182–187

    PubMed  CAS  Google Scholar 

  129. Kay DW, Forster DP, Newens AJ (2000) Long-term survival, place of death, and death certification in clinically diagnosed pre-senile dementia in northern England. Follow-up after 8–12 years. Br J Psychiatry 177:156–162

    PubMed  CAS  Google Scholar 

  130. Kilander L, Nyman H, Boberg M, Hansson L, Lithell H (1998) Hypertension is related to cognitive impairment: a 20-year follow-up of 999 men. Hypertension 31:780–786

    PubMed  CAS  Google Scholar 

  131. Kinkel WR, Jacobs L, Polachini I, Bates V, Heffner RR (1985) Subcortical arteriosclerotic encephalopathy (Binswanger’s disease). Arch Neurol 42:951–959

    PubMed  CAS  Google Scholar 

  132. Kobari M, Meyer JS, Ichijo M (1990) Leuko-araiosis, cerebral atrophy, and cerebral perfusion in normal aging. Arch Neurol 47:161–165

    PubMed  CAS  Google Scholar 

  133. Kobayashi S, Okada K, Yamashita K (1991) Incidence of silent lacunar lesion in normal adults and its relation to cerebral blood flow and risk factors. Stroke 22:1379–1383

    PubMed  CAS  Google Scholar 

  134. Kohlmeyer K (1988) Periventrikuläre Dichteminderungen des Großhirnhemisphärenmarks in Computertomogrammen von neuropsychiatrischen Patienten in der zweiten Lebenshälfte. Diagnostische Bedeutung and Pathogenese. Fortschr Neurol Psychiatr 56:279–287

    PubMed  CAS  Google Scholar 

  135. Krishnan KR, Hays JC, Blazer DG (1997) MRI-defined vascular depression. Am J Psychiatry 154:497–501

    PubMed  CAS  Google Scholar 

  136. Kurucz J, Charbonneau R, Kurucz A, Ramsey P (1981) Quantitative clinicopathologic study of cerebral amyloid angiopathy. J Am Geriatr Soc 29:61–69

    PubMed  CAS  Google Scholar 

  137. Ladurner G, Jeindl E, Schneider G (1982) Die Beziehung zwischen multiplen Infarkten and vaskulärer (Multiinfarkt-)Demenz. Fortschr Neurol Psychiatr 50: 124–127

    Google Scholar 

  138. Lai SM, Alter M, Friday G, Sobel E (1994) A multifactorial analysis of risk factors for recurrence of ischemic stroke. Stroke 25:958–962

    PubMed  CAS  Google Scholar 

  139. Launer LJ, Masaki K, Petrovitch H, Foley D, Havlik RJ (1995) The association between midlife blood pressure levels and late-life cognitive function. The Honolulu-Asia Aging Study. JAMA 274:1846–1851

    PubMed  CAS  Google Scholar 

  140. Lee SC, Park SJ, Ki HK, Gwon HC, Chung CS, Byun HS, Shin KJ, Shin MH, Lee WR (2000) Prevalence and risk factors of silent cerebral infarction in apparently normal adults. Hypertension 36:73–77

    PubMed  CAS  Google Scholar 

  141. Lin JX, Tomimoto H, Akiguchi I, Matsuo A, Wakita H, Shibasaki H, Budka H (2000) Vascular cell components of the medullary arteries in Binswanger’s disease brains: a morphometric and immunoelectron microscopic study. Stroke 31:1838–1842

    PubMed  CAS  Google Scholar 

  142. Lipsey JR, Robinson RG, Pearlson GD (1984) Nortriptyline treatment for post stroke depression: a double trial. Lancet i:297–300

    Google Scholar 

  143. Liu CK, Miller BL, Cummings JL, Mehringer CM, Goldberg MA, Howng SL, Benson DF (1992) A quantitative MRI study of vascular dementia. Neurology 42:138–143

    PubMed  CAS  Google Scholar 

  144. Liu S, Manson JE, Stampfer MJ, Rexrode KM, Hu FB, Rimm EB, Willett WC (2000) Whole grain consumption and risk of ischemic stroke in women: A prospective study. JAMA

    Google Scholar 

  145. Loeb C (1989) The lacunar syndromes. Eur Neurol 29, Suppl 2:2–7

    Google Scholar 

  146. Loeb C (1990) Vascular dementia: terminology and classification. In: Chopra JS, Jagannathan K, Sawhney IMS, Lechner H, Szendey GL (eds) Current concepts in stroke and vascular dementia. Elsevier, Amsterdam, pp 73–82

    Google Scholar 

  147. Loeb C, Gandolfo C, Bino G (1988) Intellectual impairment and cerebral lesions in multiple cerebral infarcts. Stroke 19:560–565

    PubMed  CAS  Google Scholar 

  148. Loeb C, Gandolfo C, Croce R, Conti M (1992) Dementia associated with lacunar infarction. Stroke 23:1225–1229

    PubMed  CAS  Google Scholar 

  149. Lyness JM, Caine ED, King DA, Conwell Y, Cox C (1999) Duberstein PR Cerebro-vascular risk factors and depression in older primary care patients: testing a vascular brain disease model of depression. Am J Geriatr Psychiatry 7:252–258

    PubMed  CAS  Google Scholar 

  150. Lyness JM, King DA, Conwell Y, Cox C, Caine ED (2000) Cerebrovascular risk factors and 1-year depression outcome in older primary care patients. Am J Psychiatry 157:1499–1501

    PubMed  CAS  Google Scholar 

  151. Mancardi GL, Romagnoli P, Tassinari T, Gandolfo C, Primavera A, Loeb C (1988) Lacunae and cribiform cavities of the brain. Eur Neurol 28:11–17

    PubMed  CAS  Google Scholar 

  152. Mesulam M-M (1985) Patterns in behavioral neuroanatomy: association areas, the limbic system, and hemispheric specialization. In: Mesulam M-M (ed) Principles of behavioral neurology. Davis, Philadelphia, pp 1–70

    Google Scholar 

  153. Meyer JS, McClintic KL, Rogers RL, Sims P, Mortel KF (1988) Aetiological considerations and risk factors for multi-infarct dementia. J Neurol, Neurosurg, Psychiatry 51:1489–1497

    CAS  Google Scholar 

  154. Meyer JS, Rauch G, Rauch RA, Hague A (2000) Risk factors for cerebral hypoperfusion, mild cognitive impairment, and dementia. Neurobiol Aging 21:161–169

    PubMed  CAS  Google Scholar 

  155. Mesulam MM (1985) Principles of behavioral neurology. Davis, Philadelphia

    Google Scholar 

  156. Mesulam MM (1990) Large-scale neurocognitive networks and distributed processing for attention, language, and memory. Ann Neurol 28:597–613

    PubMed  CAS  Google Scholar 

  157. Milionis HJ, Winder AF, Mikhailidis DP (2000) Lipoprotein (a) and stroke. J Clin Pathol 53:487–496

    PubMed  CAS  Google Scholar 

  158. Mielke R, Herholz K, Grond M, Kessler J, Heiss W-D (1992) Severity of vascular dementia is related to volume of metabolically impaired tissue. Arch Neurol 49:909–913

    PubMed  CAS  Google Scholar 

  159. Morrison AC, Fornage M, Liao D, Boerwinkle E (2000) Parental history of stroke predicts subclinical but not clinical stroke: the Atherosclerosis Risk in Communities Study. Stroke 31:2098–2102

    PubMed  CAS  Google Scholar 

  160. Moseley IF, Radii EW (1979) Factors influencing the development of periventricular lucencies in patients with raised intracranial pressure. Neuroradiology 17:65–68

    PubMed  CAS  Google Scholar 

  161. Moulin T, Tatu L, Crepin-Leblond T, Chavot D, Berges S, Rumbach T (1997) The Besancon Stroke Registry: an acute stroke registry of 2500 consecutive patients. Eur Neurol 38:10–20

    PubMed  CAS  Google Scholar 

  162. Neau JP, Ingrand P, Couderq C, Rosier MP, Bailbe M, Dumas P, Vandermarcq P, Gil R (1997) Recurrent intracerebral hemorrhage. Neurology 49:106–113

    PubMed  CAS  Google Scholar 

  163. Oberpichler-Schwenk H, Peruche B (1995) Schlaganfall-Pathophysiologie and Pharmakotherapie. Arnzeimitteltherapie 13:169–177

    Google Scholar 

  164. O’Brien MD (1990) Vascular disease and dementia. In: Chopra JS, Jagannathan K, Sawhney IMS, Lechner H, Szendey GL (eds) Current concepts in stroke and vascular dementia. Elsevier, Amsterdam, S 97–102

    Google Scholar 

  165. O’Brien J, Perry R, Barber R, Gholkar A, Thomas A (2000) The association between white matter lesions on magnetic resonance imaging and noncognitive symptoms. Ann N Y Acad Sci 903:482–489

    PubMed  Google Scholar 

  166. O’Connell JE, Gray CS, French JM, Robertson IH (1998) Atrial fibrillation and cognitive function: case-control study. J Neurol Neurosurg Psychiatry 65:386–389

    PubMed  Google Scholar 

  167. Oder W, Binder H, Baumgartner C, Zeller K, Deecke L (1988) Zur Prognose der sozialen Reintegration nach Schlaganfall. Rehabilitation 27:85–90

    PubMed  CAS  Google Scholar 

  168. Ojemann RG, Heros RC (1983) Spontaneous brain hemorrhage. Stroke 14:468–475

    PubMed  CAS  Google Scholar 

  169. Olszewski J (1962) Subcortical arteriosclerotic encephalopathy. World Neurol 3:359–375

    PubMed  CAS  Google Scholar 

  170. Olichney JM, Hansen LA, Hofstetter CR, Lee JH, Katzman R, Thal LJ (2000) Association between severe cerebral amyloid angiopathy and cerebrovascular lesions in Alzheimer disease is not a spurious one attributable to apolipoprotein E4. Arch Neurol 57:869–874

    PubMed  CAS  Google Scholar 

  171. Ott E (1991) Rheological therapy of vascular dementia: a rational basis? In: Hartmann A, Kuschinsky W, Hoyer S (eds) Cerebral ischemia and dementia. Springer, Berlin, pp 424–431

    Google Scholar 

  172. Ott A, Breteler MM, de Bruyne MC, van Harskamp F, Grobbee DE, Hofman A (1997) Atrial fibrillation and dementia in a population-based study. The Rotterdam Study. Stroke 28 (1997) 316–321

    PubMed  CAS  Google Scholar 

  173. Ottenbacher KJ, Jannell S (1993) The results of clinical trials in stroke rehabilitation research. Arch Neurol 50:37–44

    PubMed  CAS  Google Scholar 

  174. Pantoni L, Rossi R, Inzitari D, Bianchi C, Beneke M, Erkinjuntti T, Wallin A (2000) Efficacy and safety of nimodipine in subcortical vascular dementia: asubgroup analysis of the Scandinavian Multi-Infarct Dementia Trial. J Neurol Sci 175:124–134

    PubMed  CAS  Google Scholar 

  175. Paciaroni M, Eliasziw M, Sharpe BL, Kappelle LJ, Chaturvedi S, Meldrum H, Barnett HJ (2000) Long-term clinical and angiographie outcomes in symptomatic patients with 70 to 99% carotid artery stenosis. Stroke 31:2037–2042

    PubMed  CAS  Google Scholar 

  176. Petrovitch H, White LR, Izmirilian G, Ross GW, Havlik RJ, Markesbery W, Nelson J, Davis DG, Hardman J, Foley DJ, Launer LJ (2000) Midlife blood pressure and neuritic plaques, neurofibrillary tangles, and brain weight at death: the HAAS. Honolulu-Asia aging Study. Neurobiol Aging 21:57–62

    PubMed  CAS  Google Scholar 

  177. Pohjasvaara T, Mantyla R, Ylikoski R, Kaste M, Erkinjuntti T (2000) Comparison of different clinical criteria (DSM-III, ADDTC, ICD-10, NINDS-AIREN, DSM-IV) for the diagnosis of vascular dementia. Stroke 2000:2952–2957

    Google Scholar 

  178. Poeck K (1989) Chronische vaskuläre Enzephalopathie. DMW 114:1582–1587

    CAS  Google Scholar 

  179. Poirier J, Gray F, Gherardi R, Derouesne C (1985) Cerebral lacunae. A proposed new classification. J Neuropathol Exp Neurol 44:312

    Google Scholar 

  180. Reed T, Kirkwood SC, DeCarli C, Swan GE, Miller BL, Wolf PA, Jack LM, Carmelli D (2000) Relationship of family history scores for stroke and hypertension to quantitative measures of white-matter hyperintensities and stroke volume in elderly males. Neuroepidemiology 19:76–86

    PubMed  CAS  Google Scholar 

  181. Richards SS, Emsley CL, Roberts J, Murray MD, Hall K, Gao S, Hendrie HC (2000) The association between vascular risk factor-mediating medications and cognition and dementia diagnosis in a community-based sample of African-Americans. J Am Geriatr Soc 48:1035–1041

    PubMed  CAS  Google Scholar 

  182. Ringelstein EB, Zeumer H, Schneider R (1985) Der Beitrag der zerebralen Computertomographie zur Differentialdiagnose und Differentialtherapie des ischämischen Großhirninfarktes. Fortschr Neurol Psychiat 53:315–334

    PubMed  CAS  Google Scholar 

  183. Ringelstein EB, Weiller C (1990) Hirninfarktmuster im Computertomogramm. Nervenarzt 61:462–471

    PubMed  CAS  Google Scholar 

  184. Robinson RG, Bolduc PL, Price TR (1987) Two-year longitudinal study of post-stroke mood disorders: diagnosis and outcome at one and two years. Stroke 18:837–843

    PubMed  CAS  Google Scholar 

  185. Robinson RG, Travella JI (1996) Neuropsychiatry of mood disorders. In: Fogel BS, Schiffer RB, Rao SM (eds) Neuropsychiatry, Davis, Baltimore, S 287–305

    Google Scholar 

  186. Rogers RL, Meyer JS, Mortel KF, Mahurin RK, Judd BW (1986) Decreased cerebral blood flow precedes multi-infarct dementia, but follows senile dementia of Alzheimer type. Neurology 36:1–6

    PubMed  CAS  Google Scholar 

  187. Roman GC (1987) Senile dementia of the Binswanger type. JAMA 258:1782–1788

    PubMed  CAS  Google Scholar 

  188. Roman GC, Tatemichi TK, Erkinjuntti T, Cummings JL, Masdeu JC, Garcia JH, Amaducci L, Brun A, Hofman A, Moody DM, O’Brien MD, Yamaguchi T, Graf-man J, Drayer BP, Bennett DA, Fisher M, Ogata J, Kokmen E, Bermejo F, Wolf PA, Gorelick PB, Bick KL, Pajeau AK, Bell MA, DeCarli C, Culebras A, Korczyn AD, Bogousslaysky J, Hartmann A, Scheinberg P (1993) Vascular dementia: Diagnostic criteria for research studies. Report of the NINDS-AIREN International Workshop. Neurology 43:250–260

    PubMed  CAS  Google Scholar 

  189. Sabatini T, Frisoni GB, Barbisoni P, Bellelli G, Rozzini R, Trabucchi M (2000) Atrial fibrillation and cognitive disorders in older people. J Am Geriatr Soc 48:387–390

    PubMed  CAS  Google Scholar 

  190. Sabri O, Hellwig D, Schreckenberger M, Schneider R, Kaiser HJ, Wagenknecht G, Setani K, Reinartz P, Zimny M, Mull M, Ringelstein EB, Bull U (2000) One-year follow-up of neuropsychology, MRI, rCBF and glucose metabolism (rMRG1u) in cerebral microangiopathy. Nuklearmedizin 39:43–49

    PubMed  CAS  Google Scholar 

  191. Schmidt R, Fazekas F, Kleinert G, Offenbacher H, Gindl K, Payer F, Freidl W, Niederkorn K, Lechner H (1992) Magnetic resonance imaging signal hyperintenties in the deep and subcortical white matter. Arch Neurol 49:825–827

    PubMed  CAS  Google Scholar 

  192. Schmidt R, Fazekas F, Offenbacher H, Dusek T, Zach E, Reinhart R, Grieshofer P, Freidl W, Eber B, Schumacher M, Koch M, Lechner H (1993) Neuropsychologic correlates of MRI white matter hyperintensities: a study of 150 normal volunteers. Neurology 43:2490–2494

    PubMed  CAS  Google Scholar 

  193. Schmidt R, Fazekas F, Koch M, Kapeller P, Augustin M, Offenbacher H, Fazekas G, Lechner H (1995) Magnetic resonance imaging cerebral abnormalities and neuropsychologic test performance in elderly hypertensive subjects. A case-control study. Arch Neurol 52:905–910

    PubMed  CAS  Google Scholar 

  194. Schmidt R, Fazekas F (1997) Klinische Bedeutung and neuropathologische Basis der `Leukoaraiose’. In: Förstl H (Hrsg) Lehrbuch der Gerontopsychiatrie. Enke, Stuttgart, S 108–116

    Google Scholar 

  195. Seno H, Ishino H, Inagaki T, Yamamori C, Miyaoaka T (2000) Comparison between multiple lacunar infarcted patients with and without dementia in nursing homes in shimane prefecture, Japan. Dement Geriatr Cogn Disord 11:161–165

    PubMed  CAS  Google Scholar 

  196. Soares JC, Mann JJ (1997) The anatomy of mood disorders - review of structural neuroimaging studies. Biol Psychiatry 41:86–106

    PubMed  CAS  Google Scholar 

  197. Starkstein SE, Robinson RG (1989) Affective disorders and cerebral vascular disease. Br J Psychiatry 154:170–182

    Google Scholar 

  198. Starkstein SE, Robinson RG (1992) Neuropsychiatric aspects of cerebral vascular disorders. In: Yudofsky SC, Hales RE (eds) Textbook of Neuropsychiatry, 2 a edn. American Psychiatric Press, Washington, pp 449–472

    Google Scholar 

  199. Sultzer DL, Mahler ME, Cummings JL, Van Gorp WG, Hinkin CH, Brown C (1995) Cortical abnormalities associated with subcortical lesions in vascular dementia. Clinical and positron emission tomographic findings. Arch Neurol 52:773–780

    PubMed  CAS  Google Scholar 

  200. Szelies B, Herholz K, Pawlik G, Karbe H, Hebold I, Heiss W-D (1991) Widespread functional effects of discrete thalamic infarction. Arch Neurol 48:178–182

    PubMed  CAS  Google Scholar 

  201. Tatemichi TK, Foulkes MA, Mohr JP, Hewitt JR, Hier DB, Price TR, Wolf PA (1990) Dementia in stroke survivors in the stroke data bank cohort. Stroke 21:858–866

    PubMed  CAS  Google Scholar 

  202. Tatemichi TK, Desmond DW, Mayeux R, Paik M, Stern Y, Sano M, Remien RH, Williams JBW, Mohr JP, Hauser WA, Figueroa M (1992) Dementia after stroke: Baseline frequency, risks, and clinical features in a hospitalized cohort. Neurology 42:1185–1193

    PubMed  CAS  Google Scholar 

  203. Tatemichi TK, Desmond DW, Paik M, Figueroa M, Gropen TI, Stern Y, Sano M, Remien R, Wiliams JBW, Mohr JP, Mayeux R (1993) Clinical determinants of dementia related to stroke. Ann Neurol 33:568–575

    PubMed  CAS  Google Scholar 

  204. Tomlinson BE, Blessed G, Roth M (1970) Observations on the brains of demented old people. J Neurol Sci 11:331–356

    Google Scholar 

  205. Tomonaga M, Yamanouchi H, Toghi H, Kameyama M (1982) Clinicopathologic study of progressive subcortical vascular encephalopathy (Binswanger Type) in the elderly. J Am Geriat Soc 30:524–529

    PubMed  CAS  Google Scholar 

  206. Torvik A (1984) The pathogenesis of watershed infarcts in the brain. Stroke 15:221–223

    PubMed  CAS  Google Scholar 

  207. Tullberg M, Mansson JE, Fredman P, Lekman A, Blennow K, Ekman R, Rosengren LE, Tisell M, Wikkelsö C (2000) CSF sulfatide distinguishes between normal pressure hydrocephalus and subcortical arteriosclerotic encephalopathy. J Neurol Neurosurg Psychiatry 69:74–81

    PubMed  CAS  Google Scholar 

  208. Tupler LA, Coffey CE, Logue PE, Djang WT, Fagan SM (1992) Neuropsychological importance of subcortical white matter hyperintensity. Arch Neurol 49:1248–1252

    PubMed  CAS  Google Scholar 

  209. Tuszynski MH, Petito CK, Levy DE (1989) Risk factors and clinical manifestations of pathologically verified lacunar infarctions. Stroke 20:990–999

    PubMed  CAS  Google Scholar 

  210. Ulrich J, Probst A, West M (1986) The brain diseases causing senile dementia. J Neurol 233:118–122

    PubMed  CAS  Google Scholar 

  211. Van Swieten JC, Geyskes GG, Derix MMA, Peeck BM, Ramos LMP, van Latum JC, van Gijn J (1991) Hypertension in the elderly is associated with white matter lesions and cognitive decline. Ann Neurol 30:825–830

    PubMed  CAS  Google Scholar 

  212. Vinters HV (1987) Cerebral amyloid angiopathy. A critical review. Stroke 18:311324

    Google Scholar 

  213. Viitanen M, Kalimo H (2000) CADASIL: hereditary arteriopathy leading to multiple brain infarcts and dementia. Ann N Y Acad Sci 903:273–284

    PubMed  CAS  Google Scholar 

  214. Voko Z, Bots ML, Hofman A, Koudstaal PJ, Witteman JC, Breteler MM (1999) J-shaped relation between blood pressure and stroke in treated hypertensives. Hypertension 34:1181–1185

    PubMed  CAS  Google Scholar 

  215. von Maravic M (1998) Neurologische Notfälle. In Braun J, Preuss R (Hrsg) Klinikleitfaden Intensivmedizin, 4. Aufl. Urban Fischer, Stuttgart, S 277–314

    Google Scholar 

  216. Wade DT, Legh-Smith J, Hewer RL (1987) Depressed mood after stroke: a community study of its frequency. Br J Psychiatry 151:200–205

    PubMed  CAS  Google Scholar 

  217. Wallin A, Blennow K (1991) Pathogenetic basis of vascular dementia. Alzheimer Dis Ass Dis 5:91–102

    CAS  Google Scholar 

  218. Wallin A, Sjogren M, Edman A, Blennow K, Regland B (2000) Symptoms, vascular risk factors and blood-brain barrier function in relation to CT white-matter changes in dementia. Eur Neurol 44:229–235

    PubMed  CAS  Google Scholar 

  219. Wannamethee SG, Shaper AG, Ebrahim S (2000) HDL-Cholesterol, total cholesterol, and the risk of stroke in middle-aged British men. Stroke 31:1882–1888

    PubMed  CAS  Google Scholar 

  220. Watkins ML, Erickson JD, Thun MJ, Mulinare J, Heath CW Jr (2000) Multivitamin use and mortality in a large prospective study. Am J Epidemiol 152:149–162

    PubMed  CAS  Google Scholar 

  221. Weiller C, Menges C, Seiler U (1992) Multiple Sklerose und subkortikale arteriosklerotische Enzephalopthie in der klinischen Differentialdiagnose. Nervenarzt 63:746–750

    PubMed  CAS  Google Scholar 

  222. Wetterling T (1992) Subkortikale arteriosklerotische Enzephalopathie - eine Krankheitsentität? Nervenheilkunde 11:289–293

    Google Scholar 

  223. Wetterling T (1994) Differentialdiagnose dementieller Abbauprozesse. Thieme, Stuttgart

    Google Scholar 

  224. Wetterling T (1995) Amnestisches Syndrom-Stand der Forschung. Fortschr Neu-rol Psychiat 63:402–410

    CAS  Google Scholar 

  225. Wetterling T (1996) Therapeutische Strategien bei vaskulärer Demenz. Fortschr Med 114:445–450

    PubMed  CAS  Google Scholar 

  226. Wetterling T (1998) Vaskuläre Demenz - ein schlüssiges Konzept? Z Geriatr Gerontol 31:36–45

    CAS  Google Scholar 

  227. Wetterling T (1998) Vascular depression - a concise concept? Eur Psychiatry 13, Suppl 4:167s

    Google Scholar 

  228. Wetterling T (1999) Vaskuläre Depression - ein schlüssiges Konzept? Fortschr Neurol Psychiat 67:327–335

    PubMed  CAS  Google Scholar 

  229. Wetterling T (2000) Zerebrovaskuläre Erkrankungen. In: Förstl H (Hrsg) Klinische Neuro-psychiatrie. Thieme, Stuttgart, S 252–269

    Google Scholar 

  230. Wetterling T (2000) Alkoholfolgeerkrankungen. In: Förstl H (Hrsg) Klinische Neuropsychiatrie. Thieme, Stuttgart, S 354–366

    Google Scholar 

  231. Wetterling T (2001) Gerontopsychiatrie. Ein Leitfaden für Diagnostik und Therapie. Springer, Berlin

    Google Scholar 

  232. Wetterling T, Reger K-H, Borgis K-J (1989) Diagnostische Wertigkeit von Marklager-Hypodensitäten im cCT. In: Fischer P-A, Baas H, Enzensberger W (Hrsg) Verhandlungen der deutschen Gesellschaft für Neurologie 5. Springer, Berlin, S 331–333

    Google Scholar 

  233. Wetterling T, Borgis K-J (1992) Patienten mit Marklager-Hypodensitäten im CT. Klinische diagnostische Einordnung. Nervenheilkunde 11:289–293

    Google Scholar 

  234. Wetterling T, Borgis K-J (1993) Vaskuläre Demenz - Ist eine klinische Unterscheidung möglich und sinnvoll? Akt Neurol 20:40–48

    Google Scholar 

  235. Wetterling T, Kanitz R-D, Borgis K-J (1993) Clinical evaluation of the ICD-10 criteria for vascular dementia. Eur Arch Psychiatry Clin Neurosci 243:30–39

    Google Scholar 

  236. Wetterling T, Kanitz R-D, Borgis K-J (1996) Comparison of different diagnostic criteria for vascular dementia (ADDTC, DSM-IV, ICD-10, NINDS-AIREN). Stroke 27:30–36

    PubMed  CAS  Google Scholar 

  237. Wiesner G, Grimm J, Bittner E (1999) Schlaganfall: Prävalenz, Inzidenz, Trend, Ost-West-Vergleich. Erste Ergebnisse aus dem Bundes-Gesundheitssurvey 1998. Gesundheitswesen 61 Spec No:S79–84

    Google Scholar 

  238. Williams PS, Rands G, Orrel M, Spector A (2000) Aspirin for vascular dementia (Cochrane Review). Cochrane Database Syst Rev 4:CD001296

    Google Scholar 

  239. Wiszniewska M, Devuyst G, Bogousslaysky J, Ghika J, van Melle G (2000) What is the significance of leukoaraiosis in patients with acute ischemic stroke? Arch Neurol 57:967–973

    PubMed  CAS  Google Scholar 

  240. Wolfe CD, Giroud M, Kolominsky-Rabas P, Dundas R, Lemesle M, Heuschmann P, Rudd A (2000) Variations in stroke incidence and survival in 3 areas of Europe. European Registries of Stroke (EROS) Collaboration. Stroke 31:2074–2079

    PubMed  CAS  Google Scholar 

  241. Wolfe N, Linn R, Babikian VL, Knoefel JE, Albert ML (1990) Frontal systems impairment following multiple lacunar infarcts. Arch Neurol 47:129–132

    PubMed  CAS  Google Scholar 

  242. Yamada M (2000) Cerebral amyloid angiopathy: an overview. Neuropathology 20:8–22

    PubMed  CAS  Google Scholar 

  243. Yamada M, Tsukagoshi H, Otomo E, Hayakawa M (1987) Cerebral amyloid angiopathy in the aged. J Neurol 234:371–376

    PubMed  CAS  Google Scholar 

  244. Yamada M, Tsukagoshi H, Otomo E, Hayakawa M (1988) Systemic amyloid deposition in old age and dementia of Alzheimer type: the relationship of brain amyloid to other amyloid. Acta Neuropathol 77:136–141

    PubMed  CAS  Google Scholar 

  245. Yao H, Sadoshima S, Ibayashi S, Kuwabara Y, Ichiya Y, Fujishima M (1992) Leukoaraiosis and dementia in hypertensive patients. Stroke 23:1673–1677

    PubMed  CAS  Google Scholar 

  246. Yoshitake T, Kiyohara Y, Katao I, Ohmura T, Iwamoto H, Nakayama K, Ohmori S, Nomiyama K, Kawano H, Ueda K, Sueishi K, Tsuneyoshi M, Fujishima M (1995) Incidence and risk factors of vascular dementia and Alzheimers disease in a defined elderly Japanese population: The Hisayama study. Neurology 45:1161–1168

    PubMed  CAS  Google Scholar 

  247. You R, McNeil JJ, O’Malley HM, Davis SM, Donnan GA (1995) Risk factors for lacunar infarction syndromes. Neurology 45:1483–1487

    PubMed  CAS  Google Scholar 

  248. Young JB, Forster A (1992) The Bradford community stroke trial: results at six months. Brit Med J 304:1085–1089

    PubMed  CAS  Google Scholar 

  249. Zeumer H, Hacke W, Hündgen R (1981) Subkortikale arteriosklerotische Enzephalopathie. Klinische, CT-morphologische and elektrophysiologische Befunde. Fortschr Neurol Psychiat 49:223–231

    PubMed  CAS  Google Scholar 

  250. Zhu L, Fratiglioni L, Guo Z, Winblad B, Viitanen M (2000) Incidence of stroke in relation to cognitive function and dementia in the Kungsholmen Project. Neurology 54:2103–2107

    PubMed  CAS  Google Scholar 

  251. Zito M, Muscari A, Marini E, Di Iorio A, Puddu GM, Abate G (1996) Silent lacunar infarcts in elderly patients with chronic non valvular atrial fibrillation. Aging (Milano) 8:341–346

    CAS  Google Scholar 

  252. Zodpey SP, Tiwari RR, Kulkarni HR (2000) Risk factors for haemorrhagic stroke: a case-control study. Public Health 114:177–182

    PubMed  CAS  Google Scholar 

  253. Zuber M, Mas JL (1992) Epidemiologie des accidents vasculaires cerebraux. Rev Neurol 148:243–255

    PubMed  CAS  Google Scholar 

  254. Anonym (2000) Epidemiology of aneurysmal subarachnoid hemorrhage in Australia and New Zealand: incidence and case fatality from the Australasian Cooperative Research on Subarachnoid Hemorrhage Study (ACROSS). Stroke 31:1843–1850

    Google Scholar 

  255. Special report from the National Institute of Neurological Disorders and Stroke (1990) Classification of Cerebrovascular Diseases III. Stroke 21:637–676

    Google Scholar 

Literatur

  1. American Academy of Neurology AIDS Taskforce (1991) Nomenclature and research case definitions for neurologic manifestations of HIV-1 infection. Neurology 41:778–785

    Google Scholar 

  2. Ashe J, Rosen SA, McArthur JC, Davis LE (1993) Bacterial, fungal, and parasitic causes of dementia. In: Whitehouse PJ (eds) Dementia. Davis, Philadelphia, pp 276–306

    Google Scholar 

  3. Beaman BL, Beaman L, Kjelstrom JA, Ogata SA (1994) Bacteria and neurodegeneration. In: Calne DB (eds) Neurodegenerative diseases. Saunders, Philadelphia, pp 319–338

    Google Scholar 

  4. bmgesundheit.de/themen (2001)

    Google Scholar 

  5. Brainin M, Presslich O, Eichberger G, Friedmann A, Marksteiner A, Maida E (1982) Akute virale Enzephalitis mit primar psychotischer Symptomatik - Diagnose, Verlauf und Prognose. Fortschr Neurol Psychiatr 50:387–395

    PubMed  CAS  Google Scholar 

  6. Braune H-J (1991) Lyme-Borreliose-Epidemiologie, Ätiologie, Diagnostik und Therapie. Fortschr Neurol Psychiatr 59:456–467

    PubMed  CAS  Google Scholar 

  7. Budka H (1998) HIV-associated neuropathology. In: Gendelman HE, Lipton SA, Eptein L, Swindells S (eds) The Neurology of AIDS. Chapman & Hall, New York, pp 241–260

    Google Scholar 

  8. Buge A, Chamouard JM, Rancurel G (1988) Le pronostic des encephalites herpe-tiques. Etude retrospective de 19 cas. Presse Med 17:13–16

    PubMed  CAS  Google Scholar 

  9. Centers for Disease Control (1987) Revision of the CDC surveillance case definition for acquired immunodeficiency syndrome. Morbidity and Mortality Weekly Reports 36:35–145

    Google Scholar 

  10. Centers for Disease Control (1993) 1993 sexually transmitted diseases treatment guidelines. Morbidity and Mortality Weekly Reports 42:1–102

    Google Scholar 

  11. d’Arminio Monforte A, Duca PG, Vago L, Grassi MP, Moroni M (2000) Decreasing incidence of CNS AIDS-defining events associated with antiretroviral therapy. Neurology 54:1856–1859

    PubMed  Google Scholar 

  12. Diedrich NA, Karenberg A, Peters UH (1988) Psychopathologische Bilder bei der HIV-Infektion: AIDS-Lethargie and AIDS-Demenz. Fortschr Neurol Psychiat 56: 173–185

    Google Scholar 

  13. Everall I (2000) Human immunodeficiency virus type 1 associated dementia: pathology, clinical features and treatment. In: O’Brien J, Ames D, Burns A (eds) Dementia, 2 a edn. Arnold, London, pp 878–896

    Google Scholar 

  14. Fallon BA, Nields JA (1994) Lyme disease: a neuropsychiatric illness. Am J Psychiatry 151:1571–1583

    PubMed  CAS  Google Scholar 

  15. Felgenhauer K (1982) Differentiation of humoral immune response in imflammatory diseases of the central nervous system. J Neurol 228:223–237

    PubMed  CAS  Google Scholar 

  16. Gayle HD, Hill GL (2001) Global Impact of Human Immunodeficiency Virus and AIDS. Clin Microbiol Rev 14:327–335

    PubMed  CAS  Google Scholar 

  17. Glass JD, Wesselingh SL, Seines OA, McArthur JC (1993) Clinical neuropathological correlation in HIV associated dementia. Neurology 43:2230–2237

    PubMed  CAS  Google Scholar 

  18. Grant I, Atkinson JH, Hesselink JR, Kennedy CJ, Richman DD, Spector D, McCutchan JA (1987) Evidence for early central nervous system involvement in the aquired immunodeficiency syndrome (AIDS) and other human immunodeficiency virus (HIV) infectons. Ann Int Med 107:828–836

    PubMed  CAS  Google Scholar 

  19. Grant I, Atkinson JH (1995) Psychiatric aspects of acquired immune deficiency syndrome. In: Kaplan HI, Saddock BJ (eds) Comprehensive textbook of Psychiatry. Vol VI. Williams & Wilkins, Baltimore, S1644–1669

    Google Scholar 

  20. Gray F, Adle-Biassette H, Brion F, Ereau T, le Maner I, Levy V, Corcket G (2000) Neuronal apoptosis in human immunodeficiency virus infection. J Neurovirol 6 Suppl 1: S38–43

    Google Scholar 

  21. Greenwood R, Bhalla A, Gordon A, Roberts J (1983) Behaviour disturbances during recovery from herpes simplex encephalitis. J Neurol Neurosurg Psychiatry 46:809–817

    PubMed  CAS  Google Scholar 

  22. Hacke W, Zeumer H (1981) Computertomographie bei Herpes-simplex-Encephalitis. Fortschr Röntgenstr 135:426–431

    CAS  Google Scholar 

  23. Halperin JJ, Volkman DJ, Wu P (1992) Central nervous system abnormalitis in Lyme neuroborreliosis. Neurology 41:1571–1582

    Google Scholar 

  24. Hassler D, Zöller L, Haude M, Hufnagel HD, Sonntag HG (1992) Lyme-Borreliose in einem europäischen Endemiegebiet. DMW 117:767–774

    CAS  Google Scholar 

  25. Hierons R, Janota I (1978) The late effects of necrotizing encephalitis of the temporal lobes and limbic areas: a clinico-pathological study of 10 cases. Psychol Med 8:21–42

    PubMed  CAS  Google Scholar 

  26. Hokkanen L, Poutiainen E, Valanne L, Salonen O, livanainen M, Launes J (1997) Cognitive impairment after acute encephalitis: comparison of herpes simplex and other aetiologies. J Neurol Neurosurg Psychiatry 61:478–484

    Google Scholar 

  27. Hollweg M, Riedel R-R, Goebel F-D, Schick U, Naber D (1991) Remarkable improvement of neuropsychiatric symptoms in HIV-infected patients after AZT-therapy. Klin Wochenschr 69:409–412

    PubMed  CAS  Google Scholar 

  28. Janssen RS, Cornblath DR, Epstein LG, McArthur J, Price RW (1989) Human immunodeficiency virus (HIV) infection and nervous system: Report from the American Academy of Neurology AIDS task force. Neurology 39:119–122

    PubMed  CAS  Google Scholar 

  29. Johnson BA (2000) Intracranial infections. In: Orrison WW (ed) Neuroimaging. Saunders, Philadelphia, S 767–799

    Google Scholar 

  30. Kaplan RF, Meadows M-E, Vincent LC, Logigian EL, Steere AC (1992) Memory impairment in patients with Lyme encephalopathy: Comparison with fibromyalgia and nonpsychotically depressed patients. Neurology 42:1263–1267

    PubMed  CAS  Google Scholar 

  31. Kapur N, Barker S, Burrows EH, Ellison D, Brice J, Illis LS, Scholey K, Colbourn C, Wilson B, Loates M (1994) Herpes simplex encephalitis: long term magnetic resonance imaging and neuropsychological profile. J Neurol Neurosurg Psychiatry 57:1334–1342

    PubMed  CAS  Google Scholar 

  32. Kinghorn G (1993) The re-emergence of syphilis. Br J Hosp Med 49:683–685

    PubMed  CAS  Google Scholar 

  33. Kohler J, Kern U, Kaspar J, Rhese-Köpper B, Thoden U (1988) Chronic central nervous system manifestations. Neurology 39:753–759

    Google Scholar 

  34. Korbo L, West M (2000) No loss of hippocampal neurons in AIDS patients. Acta Neuropathol 99:529–533

    PubMed  CAS  Google Scholar 

  35. Lang C (1994) Demenzen: Diagnose und Differentialdiagnose. Chapman & Hall, Weinheim

    Google Scholar 

  36. Lang CJG (2000) Infektiös und immunologisch bedingte Hirnerkrankungen. In: Förstl H (Hrsg) Klinische Neuro-Psychiatrie. Thieme, Stuttgart, S 311–331

    Google Scholar 

  37. Lauter H (1988) Die organischen Psychosyndrome. In: Kisker KP, Lauter H, Meyer J-E, Müller C, Strömgren E (Hrsg) Psychiatrie der Gegenwart 6, 3. Aufl. Springer, Berlin, S 3–56

    Google Scholar 

  38. Lyketsos CG, Hoover DR, Guccione M, Dew MA, Wesch JE, Bing EG, Treisman GJ (1996) Changes in depressive symptoms as AIDS develops. Am J Psychiatry 153: 1430–1437

    PubMed  CAS  Google Scholar 

  39. Maj M, Janssen R, Starace F, Zaudig M, Satz P, Sughondhabirom B, Luabeya M-AK, Riedel R, Ndetei D, Calil HM, Bing EG St. Louis M, Sartorius N (1994) WHO neuropsychiatric AIDS study, cross-sectional phase I. Arch Gen Psychiatry 51:39–49

    Google Scholar 

  40. Maj M, Satz P, Janssen R, Zaudig M, Starace F, Délia L, Sughondhabirom B, Mussa M, Naber D, Ndetei D, Schulte G, Sartorius N (1994) WHO neuropsychiatric AIDS study, cross-sectional phase II. Arch Gen Psychiatry 51:51–61

    PubMed  CAS  Google Scholar 

  41. Maj M, Tortoriella A (1999) Psychische Probleme und psychiatrische Störungen bei Infektionen mit HIV. In: Helmchen H, Henn F, Lauter H, Sartorius N (Hrsg) Psychische Störungen bei somatischen Krankheiten. Psychiatrie der Gegenwart 4, 4. Aufl. Springer, Berlin, S 348–363

    Google Scholar 

  42. Maschke M, Kastrup O, Esser S, Ross B, Hengge U, Hufnagel A (2000) Incidence and prevalence of neurological disorders associated with HIV since the introduction of highly active antiretroviral therapy (HAART). J Neurol Neurosurg Psychiatry 69:376–380

    PubMed  CAS  Google Scholar 

  43. McArthur JC, Roos RP, Johnson RT (1993) Viral dementias. In: Whitehouse PJ (ed) Dementia. Davis, Philadelphia, pp 237–275

    Google Scholar 

  44. Musher DM, Hamill RJ, Baughn RE (1990) Effect of human immunodeficiency virus (HIV) infection on the course of syphilis and on response to treatment. Ann Intern Med 113:872–881

    PubMed  CAS  Google Scholar 

  45. Naber D (1993) AIDS und ZNS. In: Schüttler R (Hrsg) Organische Psychosyndrome. Springer, Berlin, S 119–132

    Google Scholar 

  46. Naber D, Perro C, Schick U, Sadri I, Schmauss M, Fröschl M, Matuschke A, Goebel FD, Hippius H (1989) Psychiatrische Symptome und neuropsychiatrische Auffälligkeiten bei HIV-Infizierten. Nervenarzt 60:80–85

    PubMed  CAS  Google Scholar 

  47. Nath A (1999) Pathobiology of human immunodeficiency virus dementia. Semin Neurol 19:113–127

    PubMed  CAS  Google Scholar 

  48. Navia BA, Jordan BD, Price RW (1986) The AIDS dementia complex: I. Clinical features. Ann Neurol 19:517–524

    PubMed  CAS  Google Scholar 

  49. Navia BA, Cho ES, Petito CK, Price RW (1986) The AIDS dementia complex: II. Neuropathology. Ann Neurol 19:525–535

    PubMed  CAS  Google Scholar 

  50. Persidsky Y, Zheng J, Miller D, Gendelman HE (2000) Mononuclear phagocytes mediate blood-brain barrier comprise and neuronal injury during HIV-1-associated dementia. J Leukoc Biol 68:413–422

    PubMed  CAS  Google Scholar 

  51. Poser S, Liier W, Eichenlaub D, Pohle HD, Weber T, Jürgens S, Felgenhauer K (1988) Chronic HIV encephalitis-II. Clinical aspects. Klin Wochenschr 66:26–31

    PubMed  CAS  Google Scholar 

  52. Prange H (1987) Neurosyphilis. Edition Medizin, VCH, Weinheim, 1987

    Google Scholar 

  53. Prange H, Ritter G (1981) Epidemiologie der Neurosyphilis. Nervenarzt 52:32–35

    PubMed  CAS  Google Scholar 

  54. Reik L jr, Smith L, Khan A, Nelson W (1985) Demyelinating encephalopathy in Lyme disease. Neurology 35:267–269

    Google Scholar 

  55. Röttgers HR, Weltermann BM, Evers S, Husstedt IW (2000) Psychiatrische Akutsymptomatik als Erstmanifestation einer HIV-Infektion. Differentialdiagnostische, therapeutische und medizinrechtliche Probleme. Nervenarzt 71:404–410

    PubMed  Google Scholar 

  56. Rundell JR, Wise MG (1989) Causes of organic mood disorder. J Neuropsychiatry Clin Neurosci 1:398–400

    PubMed  CAS  Google Scholar 

  57. Scharf D (1988) Neurocystericosis. Two hundred thirty-eight cases from a California hospital. Arch Neurol 45:777–780

    PubMed  CAS  Google Scholar 

  58. Schmitt FA, Bigley JW, McKinnis R, Logue PE, Evans RW, Drucker JL (1988) Neuropsychological outcome of zidovudine (AZT) treatment of patients with AIDS and AIDS-related complex. N Engl J Med 319:1573–1578

    PubMed  CAS  Google Scholar 

  59. Schroth G, Kretschmar K, Gawehn J, Voigt K (1987) Advantage of magnetic resonance imaging in the diagnosis of cerebral infections. Neuroradiology 29:120–126

    PubMed  CAS  Google Scholar 

  60. Sheld WM, Whitley RJ, Durack DT (1991) Infections of the central nervous system. Raven, New York

    Google Scholar 

  61. Tortoriella A, Monteleone P (1999) Psychiatrische Syndrome bei Infektionerkrankungen. In: Heimchen H, Henn F, Lauter H, Sartorius N (Hrsg) Psychische Störungen bei somatischen Krankheiten. Psychiatrie der Gegenwart 4, 4. Aufl. Springer, Berlin, S 336–345

    Google Scholar 

  62. Thurnher MM, Schindler EG, Thurnher SA, Pernerstorfer-Schön H, Kleibl-Popov C, Rieger A (2000) Highly active antiretroviral therapy for patients with AIDS dementia complex: effect on MR imaging findings and clinical course. AJNR Am J Neuroradiol 21:670–678

    PubMed  CAS  Google Scholar 

  63. Tross S, Price RW, Navia B, Thaler HAT, Gold, Hirsch DA, Sidtis JJ (1988) Neuropsychological characterization of the AIDS dementia complex: a preliminary report. AIDS 2:81–88

    PubMed  CAS  Google Scholar 

  64. UNAIDS (1996) The HIV/AIDS situation in mid 1996. UNAIDS, Genf

    Google Scholar 

  65. Utley TF, Ogden JA, Gibb A, McGrath N, Anderson NE (1997) The long-term neuropsychological outcome of herpes simplex encephalitis in a series of unselected survivors. Neuropsychiatry Neuropsychol Behav Neurol 10:180–189

    PubMed  CAS  Google Scholar 

  66. Wetterling T, Schönle PW, Bardosi A, Holzgraefe M, Demierre B (1987) Acute subdural and subgaleal empyema. Neurochirugia 30:149–151

    CAS  Google Scholar 

  67. Whitley J (1991) Herpes simplex virus infections of the central nervous system: encephalitis and neonatal herpes. Drugs 42:406–427

    PubMed  CAS  Google Scholar 

Literatur

  1. Ahmed S, Bierley R, Sheikh JI, Date ES (2000) Post-traumatic amnesia after closed head injury: a review of the literature and some suggestions for further research. Brain Inj 14:765–780

    PubMed  CAS  Google Scholar 

  2. Alexander AL, Npel S, Parker DL (2000) Neurovascular magnetic resonance and computed tomography angiography. In: Orrison WW (ed) Neuroimaging. Saunders, Philadelphia, S 37–59

    Google Scholar 

  3. Andersson S, Krogstad JM, Finset A (1999) Apathy and depressed mood in acquired brain damage: relationship to lesion localization and psychophysiological reactivity. Psychol Med 29:447–456

    PubMed  CAS  Google Scholar 

  4. Bartkowski HM, Lovely MP (1986) Prognosis in coma and the perstinent vegetative state. Head Trauma Rehabil 1:1–5

    Google Scholar 

  5. Berger MS, Pitts LH, Lovely M (1985) Outcome from severe head injury in children and adolescents. J Neurosurg 62:194–199

    PubMed  CAS  Google Scholar 

  6. Black DW (1984) Mental changes resulting from subdural haematoma. Br J Psychiatry 145:200–203

    PubMed  CAS  Google Scholar 

  7. Bochmann E (1998) Evaluation in der Neuropsychologie. In: Kasten E, Schmid G, Eder R (Hrsg) Effektive neuropsychologische Behandlungsmethoden. Deutscher Psychologen Verlag, Bonn, S 11–38

    Google Scholar 

  8. Brooks N (1984) Cognitive deficits after head trauma. In: Brooks N (ed) Closed head injury. Psychological, social and family consequences. Oxford University Press, Oxford

    Google Scholar 

  9. Burke WH, Lewis FD (1986) Management of maladaptive social behavior of brain injured adult. Int J Rehabil Res 9:335–342

    PubMed  CAS  Google Scholar 

  10. Cameron MM (1978) Chronic subdural haematoma: A review of 114 cases. J Neu-rol Neurosurg Psychiatry 41:834–839

    CAS  Google Scholar 

  11. Dilling H, Mombour W, Schmidt MH (1994) Internationale Klassifikation psychischer Störungen. Forschungskriterien. Huber, Bern

    Google Scholar 

  12. Dilling H, Mombour W, Schmidt MH (2000) Internationale Klassifikation psychischer Störungen. ICD-10 Kapitel V (F) Klinisch-diagnostische Leitlinien, 3. Aufl. Huber, Bern

    Google Scholar 

  13. Eames P (1997) Traumatic brain injury. Curr Opin Psychiatry 10:49–52

    Google Scholar 

  14. Eames P, Wood R (1985) Rehabilitation after severe brain injury. A follow-up study of a behavior modification approach. J Neurol, Neurosurg, Psychiatry 48:613–619

    CAS  Google Scholar 

  15. Edelstein BA, Couture ET (1984) Behavioral assessment and rehabilitation of the traumatically brain-damaged. Plenum, New York

    Google Scholar 

  16. Feldmann B (1998) Beratung der Angehörigen hirngeschädigter Patienten. In: Kasten E, Schmid G, Eder R (Hrsg) Effektive neuropsychologische Behandlungsmethoden. Deutscher Psychologen Verlag, Bonn, S 299–310

    Google Scholar 

  17. Fenton G, McClelland R, Montgomery A, MacFlynn G, Rutherford W (1993) The postconcussional syndrome: social antecedants and psychological sequelae. Br J Psychiatry 162:493–497

    PubMed  CAS  Google Scholar 

  18. Fink GR, Markowitsch HJ (2000) Schädel-Hirn-Traumata. In: Förstl H (Hrsg) Klinische Neuro-Psychiatrie. Thieme, Stuttgart, S 332–353

    Google Scholar 

  19. Fogelholm R, Waltimo 0 (1975) Epidemiology of chronic subdural haematoma. Acta Neurochir 32:247–250

    Google Scholar 

  20. Forrest DV (1987) Psychosocial treatment in neuropsychiatry. In: Hales RE, Yudofsky SC (eds) Textbook of neuropsychiatry. American Psychiatric Press, S 387–409

    Google Scholar 

  21. Franulic A, Horta E, Maturana R, Scherpenisse J, Carbonell C (2000) Organic personality disorder after traumatic brain injury: cognitive, anatomic and psychosocial factors. A 6 month follow-up. Brain Inj 14:431–439

    PubMed  CAS  Google Scholar 

  22. Frowein RA (1980) Prognostische Beurteilung des posttraumatischen Komas. In: Wieck HH (Hrsg) Neurotraumatologie. Thieme, Stuttgart, S 78–86

    Google Scholar 

  23. Fujioka S, Matsukado Y, Kaku M, Sakurama N, Nonaka N, Miura G (1981) CT analysis of 100 cases with chronic subdural hematoma with respect to clinical manifestation and enlarging process of the hematoma. Neurol Med Chir (Tokyo) 21:1153–1160

    CAS  Google Scholar 

  24. Glenn MB, Wroblewski B, Parziale J, Levine L, Whyte J, Rosenthal M (1989) Lithium carbonate for aggressive behavior or affective instability in ten brain-injured patients. Am J Phys Med Rehabil 68:221–226

    PubMed  CAS  Google Scholar 

  25. Gobiet H (1991) Frührehabilitation von Schädelhirnverletzten. Springer, Berlin

    Google Scholar 

  26. Hackspacher J, Dern W, Jeschke HA (1991) Interdisziplinäre Zusammenarbeit in der Rehabilitation-Problemlösungen nach schweren Schädelhirntrauma. Rehabilitation 30:75–79

    PubMed  CAS  Google Scholar 

  27. Hibbard MR, Bogdany J, Uysal S, Kepler K, Silver JM, Gordon WA, Haddad L (2000) Axis II psychopathology in individuals with traumatic brain injury. Brain Inj 14:45–61

    PubMed  CAS  Google Scholar 

  28. Jellinger K, Grisold W (1982) Zur Morphologie sogenannter hirnatrophischer Prozesse. In: Das Ärztliche Gespräch, Tropon-Werke, S 55–82

    Google Scholar 

  29. Jennett, B, Teasdale G (1977) Aspects of coma after severe head injury. Lancet i (8017):878–881

    Google Scholar 

  30. Jessell TM, Sanes JR (2000) The generation and survival of nerve cells. In: Kandel ER, Schwartz JH, Jessell TM (eds) Principles of neural science, 4th edn. McGraw-Hill, New York, pp 1041–1062

    Google Scholar 

  31. Kant R, Duffy JD, Pivovarnik (1998) Prevalence of apathy following head injury. Brain Inj 12:87–92

    PubMed  CAS  Google Scholar 

  32. Kinzel W (1972) Das irreversible psychische Defektsyndrom nach Hirntrauma. Eine Übersicht über die literarische Produktion zu einem vielschichtigen Problem. Fortschr Neurol Psychiatr Grenzgeb 40:169–219

    PubMed  CAS  Google Scholar 

  33. Kock C, Fuhrmann R (1992) Neurologische Frührehabilitation - ein dringendes Erfordernis. Rehabiltation 31:217–219

    CAS  Google Scholar 

  34. Krüger J, Vogt J, Stappenbeck C, Schoof C, Pressler M (1991) EEG, CCT und MRT bei Patienten nach leichtem und mittelschweren Schädel-Hirn-Trauma. Nervenarzt 62:226–231

    PubMed  Google Scholar 

  35. Laumer R (1986) Das chronisch subdurale Hämatom unter dem Bild der zerebrovaskulären Insuffizienz. Nervenheilkunde 5:238–240

    Google Scholar 

  36. Levine AM (1988) Buspirone and agitation in head injury. Brain injury 2:165–167

    PubMed  CAS  Google Scholar 

  37. Lezak MD (1986) Psychological implications of traumatic brain damage for the patient’s family. Rehabilitation Psychology 31/4, S 241–250

    Google Scholar 

  38. Lloyd LF, Cuyo AJ (1994) Mainentenance and generalization of behaviours after treatment of persons with traumatic brain injury. Brain Inj 8:529–540

    PubMed  CAS  Google Scholar 

  39. Lovell MR, Starratt C (1992) Cognitive rehabilitation and behavior therapy of neuropsychiatric disorders. In: Yudofsky SC, Hales RE (eds) Textbok of neuropsychiatry. American Psychiatric Press, Washington, pp 741–754

    Google Scholar 

  40. Markwalder T-M (1981) Chronic subdural hematomas: a review. J Neurosurg 54:637–645

    PubMed  CAS  Google Scholar 

  41. Max JE, Koele SL, Castillo CC, Lindgren SD, Arndt S, Bokura H, Robin DA, Smith WL, Sato Y (2000) Personality change disorder in children and adolescents following traumatic brain injury. J Int Neuropsychol Soc 6:279–289

    PubMed  CAS  Google Scholar 

  42. Oddy M, Humphrey M, Uttley D (1978) Subjective impairment and social recovery after closed head injury. J Neurol Neurosurg Psychiatry 41:611–616

    PubMed  CAS  Google Scholar 

  43. Oddy M, Caughlan T, Tyerman A, Jenkins H (1985) Social adjustment after closed head injury: a further follow-up seven years after injury. J Neurol Neurosurg Psychiatry 48:564–586

    PubMed  CAS  Google Scholar 

  44. Orrison WW, Moore KR (2000) Neuroimaging and head trauma. In: Orrison WW (ed) Neuroimaging. Saunders, Philadelphia, pp 884–915

    Google Scholar 

  45. Rak A (1998) Die Behandlung von Gedächtnisstörungen. In: Kasten E, Schmid G, Eder R (Hrsg) Effektive neuropsychologische Behandlungsmethoden. Deutscher Psychologen Verlag, Bonn, S 91–124

    Google Scholar 

  46. Rao N, Jellinek HM, Woolston DC (1985) Agitation in closed head injury: haloperidol effects on rehabilitation outcome. Arch Phys Med Rehabil 66:30–34

    PubMed  CAS  Google Scholar 

  47. Russell WR, Smith A (1961) Post-traumatic amnesia in closed head injury. Arch Neurol 5:4–17

    PubMed  CAS  Google Scholar 

  48. Salazar AM, Warden DL, Schwab K, Spector J, Braverman S, Walter J, Cole R, Rosner MM, Martin EM, Ecklund J, Ellenbogen RG (2000) Cognitive rehabilitation for traumatic brain injury: A randomized trial. Defense and Veterans Head Injury Program (DVHIP) Study Group. JAMA 283:3075–3081

    PubMed  CAS  Google Scholar 

  49. Sanes JR, Jessell TM (2000) The guidances of axons to their targets. In: Kandel ER, Schwartz JH, Jessell TM (eds) Principles of neural science, 4th edn. McGraw-Hill, New York, pp 1063–1086

    Google Scholar 

  50. Schachenmayr W, Friede RL (1978) The origin of subdural neomembranes. I. Fine structure of the dura-arachnoid interface in man. Am J Pathol 92:53–68

    PubMed  CAS  Google Scholar 

  51. Scherzer E, Wurzer W (1994) Wesensänderung nach Hirntrauma. In: Suchenwirth RMA, Ritter G (Hrsg) Begutachtung der hirnorganischen Wesensänderung. Fischer, Stuttgart, S 48–61

    Google Scholar 

  52. Schmidt J (1990) Pathophysiologische Grundlagen, Stand und Perspektiven der Entwicklung von Zerebralprotektiva. 1. Pathophysiolologische Grundlagen. Z Klin Med 45:399–405

    CAS  Google Scholar 

  53. Schreiber P, Mai N (1990) Überlegungen zur spezifischen Frührehabilitation bei Patienten mit schwerem Schädel-Hirn-Trauma. Rehabilitation 29:238–241

    PubMed  CAS  Google Scholar 

  54. Seron X (1987) Operant procedures and neuropsychological rehabilitation. In: Meier MJ, Benton AL, Diller L (eds) Neuropsychological rehabilitation. Guilford, New York, pp 132–161

    Google Scholar 

  55. Silver JM, Hales RE, Yudofsky SC (1994) Neuropsychiatric aspects of traumatic brain injury. In: Yudofsky SC, Hales RE (eds) Synopsis of neuropsychiatry. American Psychiatric Press, Washington DC, pp 280–306

    Google Scholar 

  56. Stix P, Ladurner G, Flaschka G, Lechner H (1982) Die Relevanz psychiatrisch-neurologischer Symptome beim chronischen Subduralhämatom. Nervenarzt 53:580–583

    PubMed  CAS  Google Scholar 

  57. Supprian T, Müller U, Hofmann E, Becker T (1996) Psychiatrische Folgeerkrankungen nach Schädel-Hirn-Trauma - eine Literaturübersicht. Psychiatr Prax 23: 161–167

    PubMed  CAS  Google Scholar 

  58. Taber KH, Hayman LA, Diaz-Marchan PJ (2000) Intracranial hemorrhage. In: Orrison WW (ed) Neuroimaging. Saunders, Philadelphia, pp 853–883

    Google Scholar 

  59. Timmons ML, Gasquoine L, Scribak JW (1987) Functional changes with rehabilitation of very severe traumatic brain injury survivors. Head Trauma Rehabil 2:64–73

    Google Scholar 

  60. Tyerman A, Humphrey M (1984) Changes in self concept following severe head injury. Int J Rehabil Res 7:11–23

    PubMed  CAS  Google Scholar 

  61. Van Reekum R, Bayley M, Garner S, Burke IM, Fawcett S, Hart A, Thompson W (1995) N of 1 study: amantadine for the amotivational syndrome in a patient with traumatic brain injury. Brain Inj 9:49–53

    PubMed  CAS  Google Scholar 

  62. Van Reekum R, Bolago I, Finlayson MA, Garner S, Links PS (1996) Psychiatric disorders after traumatic brain injury. Brain Inj 10:319–327

    PubMed  CAS  Google Scholar 

  63. Van Zomeren AH, van den Burg W (1985) Residual complaints of patients two years after severe head injury. J Neurol, Neurosurg, Psychiatry 48:21–28

    CAS  Google Scholar 

  64. Weddell R, Oddy M, Jenkins D (1980) Social adjustment after rehabilitation: a two year follow-up of patients with severe head injury. Psychol Med 10:257–263

    PubMed  CAS  Google Scholar 

  65. Wetterling T, Demierre B, Rama B, Spoerri 0 (1986) The clinical course of surgically treated posttraumatic subdural hygromas. Acta Neurochir 83:99–104

    CAS  Google Scholar 

  66. Wetterling T, Demierre B, Rama B, Nekic B (1988) Protein analysis of subdural hygroma fluid. Acta Neurochir 91:79–82

    CAS  Google Scholar 

  67. Wetterling T, Rama B (1989) Zur Differentialdiagnose von subduralen Effusionen. Röntgen-B1 42:508–514

    CAS  Google Scholar 

  68. Wood RL (1984) Behavior disorders following severe brain injury: their presentation and psychological management. In: Brooks N (ed) Closed head injury: psychological, social and family consequences. Oxford University Press, New York, pp 195–219

    Google Scholar 

  69. World Health Organization (1993) International Classification of Diseases (ICD10), Chapter V. Diagnostic guidelines. Genf

    Google Scholar 

  70. World Health Organization (1994) International Classification of Diseases (ICD10), Chapter V. Research criteria. Genf

    Google Scholar 

  71. Wroblewski BA, Joseph AB, Cornblatt RR (1996) Antidepressant pharmacotherapy and the treatment of depression in patients with severe traumatic brain injury: a controlled, prospective study. J Clin Psychiatry 57:582–587

    PubMed  CAS  Google Scholar 

  72. Wroblewski BA, Joseph AB, Kupfer J, Kalliel K (1997) Effectiveness of valproic acid on destructive and aggressive behaviours in patients with acquired brain injury. Brain Inj 11:37–47

    PubMed  CAS  Google Scholar 

  73. Yamashima T, Yamamoto S, Friede RL (1983) The role of endothelial gap junctions in the enlargement of chronic subdural hematomas. J Neurosurg 59:298–303

    PubMed  CAS  Google Scholar 

Literatur

  1. Adams RD, Fisher CM, Hakim S, Ojemann RG, Sweet WH (1965) Symptomatic occult hydrocephalus with normal cerebrospinal fluid pressure. N Engl J Med 273:117–126

    PubMed  CAS  Google Scholar 

  2. Aimard G, Trillet M, Perroudon C, Tommasi M, Carrier H (1971) Ictus amnesique symptomatique d’un glioblastome interessant le trigone. Rev Neurol 124:392–396

    PubMed  CAS  Google Scholar 

  3. Andersson PG (1970) Intracranial tumors in a psychiatric autopsy material. Acta Psychiat Scand 46:213–224

    PubMed  CAS  Google Scholar 

  4. Anderson SW, Damasio H, Tranel D (1990) Neuropsychological impairments associated with lesions caused by tumor or stroke. Arch Neurol 47:397–405

    PubMed  CAS  Google Scholar 

  5. Bradley WG, Orrison WWW (2000) Hydrocephalus and cerebrospinal fluid flow. In: Orrison WW (ed) Neuroimaging II. Saunders, Philadelphia, pp 1704–1716

    Google Scholar 

  6. Chee CP, David A, Galbraith S, Gillham R (1985) Dementia due to meningeoma: outcome after surgical removal. Surg Neurol 23:414–416

    PubMed  CAS  Google Scholar 

  7. Dauch WA, Zimmermann R (1990) Der Normaldruck-Hydrozephalus. Fortschr Neurol Psychiatr 58:178–190

    PubMed  CAS  Google Scholar 

  8. DiChiro G, Arimitsu T, Brooks RA, Morgenthaler DG, Johnston GS, Jones E, Keller MR (1979) Computed tomography profiles of periventricular hypodensity in hydrocephalus and leukoencephalopathy. Radiology 130:661–666

    CAS  Google Scholar 

  9. Escourelle R, Poirier J (1978) Manual of basal neuropathology, 2nd edn. Saunders, Philadelphia

    Google Scholar 

  10. Fava M, Fava GA, Kellner R, Serafini E, Mastrogiacomo I (1982) Psychological correlates of hyperprolactinemia in males. Psychother Psychosom 37:214–217

    PubMed  CAS  Google Scholar 

  11. Filley CM, Kleinschmidt-DeMasters BK (1995) Neurobehavioral presentations of brain neoplasms. West J Med 163:19–25

    PubMed  CAS  Google Scholar 

  12. Frazier CH (1936) Tumor involving the frontal lobe alone: a symptomatic survey of one hundred and five verified cases. Arch Neurol Psychiatry 35:525–571

    Google Scholar 

  13. Giovagnoli AR (1993) Quality of life in patients with stable disease after surgery, radiotherapy, and chemotherapy for malignant brain tumour. J Neurol Neurosurg Psychiatry 67:358–363

    Google Scholar 

  14. Grattan-Smith PJ, Morris JGL, Shores EA, Batchelor J, Sparks RS (1992) Neuropsychological abnormalities in patients with pituitary tumours. Acta Neurol Scand 86:626–631

    PubMed  CAS  Google Scholar 

  15. Günzel H, Tennstedt A (1981) Psychische Störungen and Hirntumorwachstum. Psychiat Neurol med Psychol (Leipzig) 35:334–340

    Google Scholar 

  16. Inzitari D, Bracco L, Capparelli R, Martini P, Giordano GP, Poggessi L, Miceli M (1984) Cerebrospinal fluid dynamics, white matter degeneration, and mental deterioration in subcortical arteriosclerotic encephalopathy of Binswanger type. Monogr Neural Sci 11:150–156

    PubMed  CAS  Google Scholar 

  17. Irle E, Peper M, Wowra B, Kunze S (1994) Mood changes after surgery for tumors of the cerebral cortex. Arch Neurol 51:164–174

    PubMed  CAS  Google Scholar 

  18. Jellinger K, Grisold W (1982) Zur Morphologie sogenannter hirnatrophischer Prozesse. In: Das Ärztliche Gespräch, Tropon-Werke, S 55–82

    Google Scholar 

  19. Jellinger K (1987) Pathology of intracranial neoplasia. In: Jellinger K (ed) Therapy of malignant brain tumors. Springer, Wien, pp 1–90

    Google Scholar 

  20. Kaplan CP, Miner ME (1997) Anxiety and depression in elderly patients receiving treatment for cerebral tumours. Brain Inj 11:129–135

    PubMed  CAS  Google Scholar 

  21. Kelly WF (1996) Psychiatric aspects of Cushing’s syndrome. QJM 89:543–551

    PubMed  CAS  Google Scholar 

  22. Kurtzke JF (1984) Neuroepidemiology. Ann Neurol 16:265–277

    Google Scholar 

  23. Lampl Y, Barak Y, Achiron A, Sarova-Pinchas I (1995) Intracranial meningeomas: Correlation of peritumoral edema and psychiatric disturbances. Psychiatry Res 58:177–180

    PubMed  CAS  Google Scholar 

  24. Lilja A, Salford LG (1997) Early mental changes in patients with astrocytomas with special reference to anxiety and epilepsy. Psychopathology 30:316–323

    PubMed  CAS  Google Scholar 

  25. Lohr JB, Cadet JL (1987) Neuropsychiatric aspects of brain tumors. In: Hales RE, Yudofsky SC (eds) Textbook of Neuropsychiatry. American Psychiatric Press, Washington, pp 351–364

    Google Scholar 

  26. Mendez MF (1993) Miscellaneous causes of dementia. In: Whitehouse PJ (ed) Dementia. Davis, Philadelphia, pp 337–358

    Google Scholar 

  27. Moseley IF, Radii EW (1979) Factors influencing the development of periventricular lucencies in patients with raised intracranial pressure. Neuroradiology 17:65–69

    Google Scholar 

  28. Orrison WW, Hart BL (2000) Intra-axial brain tumors. In: Orrison WW (ed) Neuroimaging. Saunders, Philadelphia, pp 583–611

    Google Scholar 

  29. Paal G (1981) Zur Psychopathologie des Hirntumorkranken. Fortschr Neurol Psychiatr 49:265–274

    PubMed  CAS  Google Scholar 

  30. Peiffer J (1984) Neuropathologie. In: Remmele W (Hrsg) Pathologie Band 4, Springer S 5–270

    Google Scholar 

  31. Pringle AM, Taylor R, Whittle IR (1999) Anxiety and depression in patients with an intracranial neoplasm before and after tumour surgery. Br J Neurosurg 13:46–51

    PubMed  CAS  Google Scholar 

  32. Reavley A, Fisher AD, Owen D, Creed FH, Davis JR (1997) Psychological distress in patients with hyperprolactinaemia. Clin Endocrinol (Oxf) 47:343–348

    CAS  Google Scholar 

  33. Rieke J (1975) Über depressive Psychosen im Verlaufe von Hirntumorerkrankungen. Nervenarzt 46:152–159

    PubMed  CAS  Google Scholar 

  34. Sablowski N, Pawlik K, Ludecke DK, Herrmann HD (1986) Aspects of personality in patients with pituitary adenomas. Acta Neurochir 83:8–11

    CAS  Google Scholar 

  35. Sanders WP, Chundi VV (2000) Extra-axial tumors including pituitary and para-sellar. In: Orrison WW (ed) Neuroimaging. Saunders, Philadelphia, S 612–717

    Google Scholar 

  36. Schifferdecker M, Schmidt R (1992) Lokalisationsbezogene psychopathologische Symptome bei Hirntumoren am Beispiel der Olfaktoriusmeningeome. Nervenarzt 63:175–179

    PubMed  CAS  Google Scholar 

  37. Schoenberg BS, Christine BW, Whisnant JP (1976) The descriptive epidemiology of primary intracranial neoplasms: the Connecticut experience. Am J Epidemiol 104:499–510

    PubMed  CAS  Google Scholar 

  38. Schoenberg BS, Christine BW, Whisnant JP (1978) The resolution of discrepancies in the reported incidence of primary brain tumors. Neurology 28:817–823

    PubMed  CAS  Google Scholar 

  39. Starkstein SE, Boston JD, Robinson RG (1988) Mechanisms of mania after brain injury. 12 case reports and review of the literature. J Nerv Ment Dis 176:87–100

    PubMed  CAS  Google Scholar 

  40. Tennstedt A (1982) Atypische Symptome bei Hirntumoren-Beitrag zur Topographie. Zbl allg Pathol pathol Anat 126:19–22

    CAS  Google Scholar 

  41. Thomsen AM, Börgesen SE, Bruhn P, Gjerris F (1986) Prognosis of dementia in normal-pressure hydrocephalus after a shunt operation. Ann Neurol 20:304–310

    PubMed  CAS  Google Scholar 

  42. Toghi T, Tomonaga M, Inoue K (1978) Parkinsonism and dementia with acoustic neurinomas. Report of three cases. J Neurol 217:271–279

    Google Scholar 

  43. Vanneste J, Augustjin P, Davies GAG, Dirven C, Tan WF (1992) Normal-pressure hydrocephalus. Is cisternography still useful in selecting patients for a shunt? Arch Neurol 49:366–370

    PubMed  CAS  Google Scholar 

  44. Vieregge P (2000) Hirntumoren. In: Förstl H (Hrsg) Klinische Neuro-Psychiatrie. Thieme, Stuttgart, S 298–310

    Google Scholar 

  45. Vieregge P, Gerhard L, Reinhardt V (1988) Intrakranielle raumfordernde Prozesse in der Psychiatrie - dreißigjährige klinisch-neuropathologische Katamnese. Fortschr Neurol Psychiatr 56:373–379

    PubMed  CAS  Google Scholar 

  46. Walther-Büel H (1951) Die Psychiatrie der Hirngeschwülste und die zerebralen Grundlagen psychischer Vorgänge. Acta Neurochir Suppl II, Springer, Wien

    Google Scholar 

  47. Wetterling T, Demierre B, Rama B, Spoerri O (1986) The clinical course of surgically treated posttraumatic subdural hygromas. Acta Neurochir 83:99–104

    CAS  Google Scholar 

  48. Wetterling T, Schönle PW, Bardosi A, Holzgraefe M, Demierre B (1987) Acute subdural and subgaleal empyema. Neurochirurgia 30:149–151

    Google Scholar 

  49. Wetterling T, Kanitz R-D (1993) Schizophrenie-ähnliche Psychose bei suprasellären Hypophysenadenomen. Psycho 19:261–266

    Google Scholar 

  50. Wikkelsö C, Andersson H, Blomstrand C, Lindquist G, Svendson P (1986) Normal pressure hydrocephalus. Predictive value of the cerebrospinal fluid tap-test. Acta Neurol Scand 73:566–573

    PubMed  Google Scholar 

  51. Wikkelsö C, Andersson H, Blomstrand C, Matousek M, Svendson P (1989) Computed tomography of the brain in the diagnosis of and prognosis in normal pressure hydrocephalus. Neuroradiology 31:160–165

    PubMed  Google Scholar 

  52. Zülch KJ (1965) Brain tumors, their biology and pathology, 2nd edn. Springer, New York

    Google Scholar 

Literatur

  1. Alarcon RD, Franceschini JA (1984) Hyperparathyroidism and paranoid psychosis. Br J Psychiatry 145:477–486

    PubMed  CAS  Google Scholar 

  2. Amodio P, Marchetti P, Del Piccolo F, Beghi A, Comacchio F, Carraro P, Campo G, Baruzzo L, Marchiori C, Gatta A (1997) The effect of flumazenil on subclinical psychometric or neurophysiological alterations in cirrhotic patients: a double-blind placebo-controlled study. Clin Physiol 17:533–539

    PubMed  CAS  Google Scholar 

  3. Ananth J, Swartz R, Burgoyne K, Gadasally R (1994) Hepatic disease and psychiatric illness: relationships and treatment. Psychother Psychosom 62:146–159

    PubMed  CAS  Google Scholar 

  4. Baumgartner A (1993) Schilddrüsenhormone and depressive Erkrankungen - Kritische Übersicht and Perspektiven. Teil I: Klinik. Nervenarzt 64:1–10

    PubMed  CAS  Google Scholar 

  5. Baumgartner A, Campos-Barros A (1993) Schilddrüsenhormone and depressive Erkrankungen - Kritische Übersicht and Perspektiven. Teil II: Schilddrüsenhormoue and ZNS-Ergebnisse der Grundlagenforschung. Nervenarzt 64:11–20

    PubMed  CAS  Google Scholar 

  6. Bazire S (2000) Psychotropic drug directory 2000. Mark Allen Publishing, Wilts

    Google Scholar 

  7. Bengtsson F, Bergqvist PB, Apelqvist G (1997) Brain tryptophan perturbation in hepatic encephalopathy: implications for effects by neuropsychoactive drugs in clinical practice. Adv Exp Med Biol 420:1–33

    PubMed  CAS  Google Scholar 

  8. Behar KL, Rothman DL, Petersen KF, Hooten M, Delaney R, Petroff OA, Shulman GI, Navarro V, Petrakis IL, Charney DS, Krystal JH (1999) Preliminary evidence of low cortical GABA levels in localized 1H-MR spectra of alcohol-dependent and hepatic encephalopathy patients. Am J Psychiatry 156:952–954

    PubMed  CAS  Google Scholar 

  9. Bent N, Rabbitt P, Metcalfe D (2000) Diabetes mellitus and the rate of cognitive ageing. Br J Clin Psychol 39:349–362

    PubMed  Google Scholar 

  10. Blei AT, Cordoba J (1996) Subclinical encephalopathy. Dig Dis 14 Suppl 1:2–11

    Google Scholar 

  11. Bremer BA, Wert KM, Durica AL, Weaver A (1998) Neuropsychological, physical, and psychosocial functioning of individuals with end-stage renal disease. Ann Behav Med 19:348–352

    Google Scholar 

  12. Brickman AL, Yount SE, Blaney NT, Rothberg S, De-Nour AK (1996) Pathogenesis of cognitive complaints in patients on hemodialysis. Gen Hosp Psychiatry 18:36–43

    PubMed  CAS  Google Scholar 

  13. Brown TM, Brown RL (1995) Neuropsychiatric consequences of renal failure. Psychosomatics 36:244–253

    PubMed  CAS  Google Scholar 

  14. Brownlie BE, Rae AM, Walshe JW, Wells JE (2000) Psychoses associated with thyrotoxicosis - “thyrotoxic psychosis”. A report of 18 cases, with statistical analysis of incidence. Eur J Endocrinol 142:438–444

    PubMed  CAS  Google Scholar 

  15. Burmann-Urbanek M, Sanner B, Laschewski F, Kreuzer I, Wiemann J, Konermann M, Sturm A (1995) Schlafstörungen bei Patienten mit dialysepflichtiger Niereninsuffizienz. Pneumologie 49 Suppl 1:158–160

    Google Scholar 

  16. Burn DJ, Bates D (1998) Neurology and the kidney. J Neurol Neurosurg Psychiatry 65:810–821

    PubMed  CAS  Google Scholar 

  17. Butterworth RF (1994) Cerebral dysfunction in chronic alcoholism: role of alcoholic liver disease. Alcohol Alcohol Suppl 2:259–265

    PubMed  CAS  Google Scholar 

  18. Cleare AJ, McGregor A, O’Keane V (1995) Neuroendocrine evidence for an association between hypothyroidism, reduced central 5-HT activity and depression. Clin Endocrinol (Oxf) 43:713–719

    CAS  Google Scholar 

  19. Cogan M, Corey C, Arieff AI, Wisniewski A, Clark OH, Lazarowitz V, Leach W (1978) Central nervous system manifestations of hyperparathyroidism. Am J Med 65:963–970

    PubMed  CAS  Google Scholar 

  20. Collis I, Lloyd G (1992) Psychiatric aspects of liver disease. Br J Psychiatry 161:12–22

    PubMed  CAS  Google Scholar 

  21. Cooper JD, Lazarowitz VC, Arieff AI (1978) Neurodiagnostic abnormalities in patients with acute renal renal failure: evidence for neurotoxicity of parathyroid hormone. J Clin Invest 61:1448–1455

    PubMed  CAS  Google Scholar 

  22. DiMauro S, Moraes CT (1993) Mitochondrial encephalomyopathies. Arch Neurol 50:1197–1208

    PubMed  CAS  Google Scholar 

  23. Driessen M, Wetterling T, Wedel T, Preuß R (1995) Secondary hyperparathyroidism and depression in chronic renal failure. Nephron 70:334–339

    PubMed  CAS  Google Scholar 

  24. Egberts E-H (1993) Hepatische Enzephalopathie. In: Schüttler R (Hrsg) Organische Psychosyndrome. Springer, Berlin, S 183–193

    Google Scholar 

  25. Eiber R, Berlin I, Grimaldi A, Bisserbe JC (1997) Diabete insulinodependent et pathologie psychiatrique: revue generale clinique et epidemiologique. Encephale 23:351–357

    PubMed  CAS  Google Scholar 

  26. Estrada RV, Morena J, Martinez E (1979) Pancreatic encephalopathy. Acta Neurol Scand 59:135–139

    PubMed  CAS  Google Scholar 

  27. Fahrenfort JJ, Wilterdink AM, van der Veen EA (2000) Long-term residual complaints and psychosocial sequelae after remission of hyperthyroidism. Psychoneuroendocrinology 25:201–211

    PubMed  CAS  Google Scholar 

  28. Fava M, Fava GA, Kellner R, Serafini E, Mastrogiacomo I (1982) Psychological correlates of hyperprolactinemia in males. Psychother Psychosom 37:214–217

    PubMed  CAS  Google Scholar 

  29. Fava M, Labbate LA, Abraham ME, Rosenbaum JF (1995) Hypothyroidism and hyperthyroidism in major depression revisited. J Clin Psychiatry 56:186–192

    PubMed  CAS  Google Scholar 

  30. Fazekas G, Fazekas F, Schmidt R, Flooh E, Valetitsch H, Kapeller P, Krejs GJ (1996) Pattern of cerebral blood flow and cognition in patients undergoing chronic haemodialysis treatment. Nucl Med Commun 17:603–608

    PubMed  CAS  Google Scholar 

  31. Feldmann E, Plum F (1993) Metabolic dementia. In: Whitehouse PJ (ed) Dementia. Davis, Philadelphia, S 307–336

    Google Scholar 

  32. Fraser CL, Arieff AI (1988) Nervous system complications in uremia. Ann Int Med 109:143–153

    PubMed  CAS  Google Scholar 

  33. Fukunishi I, Hasegawa A, Ohara T, Aikawa A, Hatanaka A, Suzuki J, Kikuchi M, Amagasaki K (1997) Kidney transplantation and liaison psychiatry, part I: anxiety before, and the prevalence rate of psychiatric disorders before and after, transplantation. Psychiatry Clin Neurosci 51:301–304

    PubMed  CAS  Google Scholar 

  34. Funovics JM, Fischer JE (1978) Brain energy metabolism and alternations of transmitter profils in acute hepatic coma. J Neural Transm, Suppl 14:61–67

    CAS  Google Scholar 

  35. Gatewood JW, Organ CH jr, Mead BT (1975) Mental changes associated with hyperparathyroidism. Am J Psychiatry 123:129–132

    Google Scholar 

  36. Gavard JA, Lustman PJ, Clouse RE (1993) Prevalence of depression in adults with diabetes. An epidemiological evaluation. Diabetes Care 16:1167–1178

    PubMed  CAS  Google Scholar 

  37. Goldman MB (1992) Neuropsychiatric features of endocrine disorders. In: Yudofsky SC, Hales RE (eds) Textbook of Neuropsychiatry, American Psychiatric Press, Washington, pp 519–540

    Google Scholar 

  38. Gregg EW, Yaffe K, Cauley JA, Rolka DB, Blackwell TL, Narayan KM, Cummings SR (2000) Is diabetes associated with cognitive impairment and cognitive decline among older women? Study of Osteoporotic Fractures Research Group. Arch Intern Med 160:174–180

    PubMed  CAS  Google Scholar 

  39. Green AI, Austin CP (1993) Psychopathology of pancreatic cancer. A psychobiologic probe. Psychosomatics 34:208–221

    PubMed  CAS  Google Scholar 

  40. Hauner H (1998) Verbreitung des Diabetes mellitus in Deutschland. DMW 123:777–782

    CAS  Google Scholar 

  41. Haupt M, Kurz A (1990) Die Demenz bei Hypothyreose. Fortschr Neurol Psychiatr 58:175–177

    PubMed  CAS  Google Scholar 

  42. Healton EB, Savage DG, Brust JCM, Garrett TJ, Lindenbaum J (1991) Neurologic aspects of cobalamin deficiency. Medicine (Baltimore) 70:229–245

    CAS  Google Scholar 

  43. Hein MD, Jackson IM (1990) Review: thyroid function in psychiatric illness. Gen Hosp Psychiatry 12:232–244

    PubMed  CAS  Google Scholar 

  44. Hickie I, Bennett B, Mitchell P, Wilhelm K, Orlay W (1996) Clinical and subclinical hypothyroidism in patients with chronic and treatment-resistant depression. Aust NZJ Psychiatry 30:246–252

    CAS  Google Scholar 

  45. Hollerbach S, Kullmann F, Frund R, Lock G, Geissler A, Schölmerich J, Holstege A (1997) Auditory event-related cerebral potentials (P300) in hepatic encephalopathy - topographic distribution and correlation with clinical and psychometric assessment. Hepatogastroenterology 44:1002–1012

    PubMed  CAS  Google Scholar 

  46. Howland RH (1993) Thyroid dysfunction in refractory depression: implications for pathophysiology and treatment. J Clin Psychiatry 54:47–54

    PubMed  CAS  Google Scholar 

  47. James JH, Escourrou J, Fisher E (1979) Blood brain neutral amino acid transport activity is increased after portoocaval anastomosis. Science 200:1395–1397

    Google Scholar 

  48. James JH, Zipparo V, Jeppson B, Fischer E (1979) Hyperammonemia, plasma amino acid imbalance and blood-brain amino acid transport: a unified theory of portal-systemic encephalopathy. Lancet ii:772–775

    Google Scholar 

  49. Jones EA, Weissenborn K (1997) Neurology and the liver. J Neurol Neurosurg Psychiatry 63:279–293

    PubMed  CAS  Google Scholar 

  50. Kalmijn S, Feskens EJ, Launer LJ, Stijnen T, Kromhout D (1995) Glucose intolerance, hyperinsulinaemia and cognitive function in a general population of elderly men. Diabetologia 38:1096–1102

    PubMed  CAS  Google Scholar 

  51. Kamada K, Takeuchi Y, Houkin K, Kitagawa M, Kuriki S, Ogata A, Tashiro K, Koyunagi I, Mitsumori K, Iwasaki Y (2001) Reversible brain dysfunction in MELAS: MEG, and (1)H-MRS-analysis. J Neurol Neurosurg Psychiatry 70:675–678

    PubMed  CAS  Google Scholar 

  52. Kathol RG, Delahunt JW (1986) The relationship of anxiety and depression to symptoms of hyperthyroidism using operational criteria. Gen Hosp Psychiatry 8:23–28

    PubMed  CAS  Google Scholar 

  53. Kelly WF (1996) Psychiatric aspects of Cushing’s syndrome. QJM 89:543–551

    PubMed  CAS  Google Scholar 

  54. Kew JJM, Leigh P (2000) Uncommon forms of dementia. In: O’Brien J, Ames D, Burns A (eds) Dementia, 2nd edn. Arnold, London, pp 897–912

    Google Scholar 

  55. Kimmel PL, Thamer M, Richard CM, Ray NF (1998) Psychiatric illness in patients with end-stage renal disease. Am J Med 105:214–221

    PubMed  CAS  Google Scholar 

  56. Köbberling J, Hintze G, Blossey HC, Dirks H, Emrich D, Mayer G, Schicha H (1981) Diagnostische Probleme der Hyperthyreose im höheren Lebensalter. DMW 106:973–978

    Google Scholar 

  57. Kramer L, Madl C, Stockenhuber F, Yeganehfar W, Eisenhuber E, Derfler K, Lenz K, Schneider B, Grimm G (1996) Beneficial effect of renal transplantation on cognitive brain function. Kidney Int 49:833–838

    PubMed  CAS  Google Scholar 

  58. Kugler CF, Lotterer E, Petter J, Wensing G, Taghavy A, Hahn EG, Fleig WE (1992) Visual event-related P300 potentials in early portosystemic encephalopathy. Gastroenterology 103:302–310

    PubMed  CAS  Google Scholar 

  59. Lang C (1994) Demenzen: Diagnose and Differentialdiagnose. Chapman & Hall, Weinheim

    Google Scholar 

  60. Lass P, Buscombe JR, Harber M, Davenport A, Hilson AJ (1999) Cognitive impairment in patients with renal failure is associated with multiple-infarct dementia. Clin Nucl Med 24:561–565

    PubMed  CAS  Google Scholar 

  61. Lockwood AH (1989) Neurologic complications of renal disease. Neurol Clin 7:617–627

    PubMed  CAS  Google Scholar 

  62. Lombes A, Bonilla E, DiMauro S (1989) Mitochondrial encephalomyopathies. Rev Neurol 145:671–689

    PubMed  CAS  Google Scholar 

  63. Loosen PT, Chambliss B, DeBold CR, Shelton R, Orth DN (1992) Psychiatric phenomenology in Cushing’s disease. Pharmacopsychiatry 25:192–198

    PubMed  CAS  Google Scholar 

  64. Maes M, Meltzer HY, Cosyns P, Suy E, Schotte C (1993) An evaluation of basal hypothalamic-pituitary-thyroid axis function in depression: results of a large-scaled and controlled study. Psychoneuroendocrinology 18:607–620

    PubMed  CAS  Google Scholar 

  65. Magistretti PJ, Pellerin L, Martin JL (1995) Brain energy metabolism. In: Bloom FE, Kupfer DJ (eds) Psychopharmacology. The 4th generation of progress. Raven Press, New York, pp 657–670

    Google Scholar 

  66. Mauri M, Siuforiani E, Bono G, Vignati F, Berseli ME, Attanasio R, Nappi G (1993) Memory impairment in Cushing’s disease. Acta Neurol Scand 87:52–55

    PubMed  CAS  Google Scholar 

  67. Moe SM, Sprague SM (1994) Uremic encephalopathy. Clin Nephrol 42:251–256

    PubMed  CAS  Google Scholar 

  68. Miura H, Kitagami T, Ohta T (1999) Application of the Zung self-rating depression scale to patients before and after introduction to haemodialysis. Psychiatry Clin Neurosci 53:381–391

    PubMed  CAS  Google Scholar 

  69. Moroni F, Lombardi G, Carla V, Lal S, Etienne P, Nair NPV (1986) Increase in the content of quinolinic acid in cerebrospinal fluid and frontal cortex of patients with hepatic failure. J Neurochem 47:1667–1671

    PubMed  CAS  Google Scholar 

  70. Müller N, Klages U, Günther W (1994) Hepatic encephalopathy presenting as delirium and mania. The possible role of bilirubin. Gen Hosp Psychiatry 16:138–140

    PubMed  Google Scholar 

  71. Mullen KD, Kaminsky-Russ K (1996) Pathogenesis of hepatic encephalopathy: potential future approaches. Dig Dis 14 Suppl 1:20–29

    Google Scholar 

  72. Nijst TQ, Wevers RA, Schoonderwaldt HC, Hommes OR, de Haan AFJ (1990) Vitamin B12 and folate concentrations in serum and cerebrospinal fluid of neurological patients with special reference to multiple sclerosis and dementia. J Neurol Neurosurg Psychiat 53:951–954

    PubMed  CAS  Google Scholar 

  73. Norenberg MD (1998) Astroglial dysfunction in hepatic encephalopathy. Metab Brain Dis 13:319–335

    PubMed  CAS  Google Scholar 

  74. O’Donnell K, Chung JY (1997) The diagnosis of major depression in end-stage renal disease. Psychother Psychosom 66:38–43

    PubMed  Google Scholar 

  75. Ordas DM, Labbate LA (1995) Routine screening of thyroid function in patients hospitalized for major depression or dysthymia? Ann Clin Psychiatry 7:161–165

    PubMed  CAS  Google Scholar 

  76. Passik SD, Breitbart WS (1996) Depression in patients with pancreatic carcinoma. Diagnostic and treatment issues. Cancer 78 (3 Suppl):615–626

    PubMed  CAS  Google Scholar 

  77. Passik SD, Roth AJ (1999) Anxiety symptoms and panic attacks preceding pancreatic cancer diagnosis. Psychooncology 8:268–272

    Google Scholar 

  78. Pliskin NH, Yurk HM, Ho LT, Umans JG (1996) Neurocognitive function in chronic hemodialysis patients. Kidney Int 49:1435–1440

    PubMed  CAS  Google Scholar 

  79. Puca FM, Antonaci F, Panella C, Guglielmi FW, Barone M, Francavilla A, Cerutti R (1989) Psychomotor dysfunctions in alcoholic and post-necrotic cirrhotic patients without overt encephalopathy. Acta Neurol Scand 79:280–287

    PubMed  CAS  Google Scholar 

  80. Reavley A, Fisher AD, Owen D, Creed FH, Davis JR (1997) Psychological distress in patients with hyperprolactinaemia. Clin Endocrinol (Oxf) 47:343–348

    CAS  Google Scholar 

  81. Rockel M, Teuber J, Schmidt R, Kaumeier S, Häfner H, Usadel KH (1987) Korrelation einer,Latenten Hyperthyreose` mit psychischen and somatischen Veränderungen. Klin Wochenschr 65:264–273

    PubMed  CAS  Google Scholar 

  82. Rogers MP (1985) Rheumatoid arthritis: psychiatric aspects and use of psychotropics. Psychosomatics 26:769–778

    Google Scholar 

  83. Rothermich NO, von Haam E (1941) Pancreatic encephalopathy. J Clin Endocrin 1:872–873

    Google Scholar 

  84. Sauvage MF, Marquet P, Rousseau A, Raby C, Buxeraud J, Lachatre G (1998) Relationship between psychotropic drugs and thyroid function: a review. Toxicol Appl Pharmacol 149:127–135

    PubMed  CAS  Google Scholar 

  85. Schuster MM, Ibel FF (1965) Psychosis with pancreatitis. A frequent occurrence infrequently recognized. Arch Intern Med 116:228–233

    PubMed  CAS  Google Scholar 

  86. Sharf B, Bental E (1971) Pancreatic encephalopathy. J Neurol Neurosurg Psychiatry 34:357–361

    PubMed  CAS  Google Scholar 

  87. Sonino N, Fava GA, Belluardo P, Girelli ME, Boscaro M (1993) Course of depression in Cushing’s syndrome: response to treatment and comparison with Graves’ disease. Horm Res 39:202–206

    PubMed  CAS  Google Scholar 

  88. Sourkes TL (1978) Tryptophan in hepatic coma. J Neural Transm, Suppl 14:7986 HIAA in CSF erhöht

    Google Scholar 

  89. Starkman MN, Schteingart DE (1981) Neuropsychiatric manifestations of patients with Cushing’s syndrome: relationship to cortisol and adrenocorticotropin hormone levels. Arch Intern Med 141:215–219

    PubMed  CAS  Google Scholar 

  90. Starkman MN, Schteingart DE, Schork MA (1981) Depressed mood and other psychiatric manifestations of Cushing’s syndrome: relationship to hormone levels. Psychosom Med 43:3–18

    PubMed  CAS  Google Scholar 

  91. Tappy L, Randin JP, Schwed P, Wertheimer J, Lemarchand-Beraud T (1987) Prevalence of thyroid disorders in psychogeriatric inpatients. A possible relationship of hypothyroidism with neurotic depression but not with dementia. J Am Geriatr Soc 35:526–531

    PubMed  CAS  Google Scholar 

  92. Tarter RE, Van-Thiel DH, Arria AM, Carra J, Moss H (1988) Impact of cirrhosis on the neuropsychological test performance of alcoholics. Alcohol Clin Exp Res 12:619–621

    PubMed  CAS  Google Scholar 

  93. Tarter RE, Arria AM, Van-Thiel DH (1991) Hepatic encephalopathy coexistent with alcoholism. Recent Dev Alcohol 9:205–224

    PubMed  CAS  Google Scholar 

  94. Teschan PE, Arieff AI (1985) Uremic and dialysis encephalopathies. In: McCandless DW (ed) Cerebral energy metabolism and metabolic encephalopathy. Plenum Press, New York, pp 263–286

    Google Scholar 

  95. Trzepacz PT, McCue M, Klein I, Greenhouse J, Levey GS (1988) Psychiatric and neuropsychological response to propranolol in Graves’ disease. Biol Psychiatry 23:678–688

    PubMed  CAS  Google Scholar 

  96. Trzepacz PT, McCue M, Klein I, Levey GS, Greenhouse J (1988) A psychiatric and neuropsychological study of patients with untreated Graves’ disease. Gen Hosp Psychiatry 10:49–55

    PubMed  CAS  Google Scholar 

  97. Trzepacz PT, Tarter RE, Shah A, Tringali R, Faett DG, Van Thiel DH (1994) SPECT scan and cognitive findings in subclinical hepatic encephalopathy. J Neuropsychiatry Clin Neurosci 6:170–175

    PubMed  CAS  Google Scholar 

  98. Walton NH, Bowden SC (1997) Does liver dysfunction explain neuropsychological status in recently detoxified alcohol-dependent clients? Alcohol Alcohol 32:287–295

    PubMed  CAS  Google Scholar 

  99. Weissenborn K (1994) Diagnostik and Therapie der portosystemischen Enzephalopathie. Schweiz Rundsch Med Prax 83:1059–1064

    PubMed  CAS  Google Scholar 

  100. Wetterling T (1987) Hyponatriämie-unterschätzte Komplikation bei psychiatrischen Patienten. Nervenarzt 58:625–631

    PubMed  CAS  Google Scholar 

  101. Wetterling T (1994) Differentialdiagnose dementieller Abbauprozesse. Thieme, Stuttgart

    Google Scholar 

  102. Wetterling T (2000) Alkoholfolgeerkrankungen. In: Förstl H (Hrsg) Klinische Neuro-Psychiatrie. Thieme, Stuttgart, S 354–366

    Google Scholar 

  103. Wetterling T, Kanitz R-D (1993) Schizophrenie-ähnliche Psychose bei suprasellären Hypophysenadenomen. Psycho 19:261–266

    Google Scholar 

  104. Wetterling T, Driessen M, Wedel T, Preuß (1995) Parathormon - ein wichtiger Faktor in der Pathogenese der urämischen Enzephalopathie? In: Jerusalem F, Ries F (Hrsg) Verhandlungen der deutschen Gesellschaft für Neurologie 8. Kölln-Druck, Bonn, S 110–111

    Google Scholar 

  105. Whelan T, Schteingart DE, Starkman MN, Smith A (1980) Neuropsychological deficits in Cushing’s syndrome. J Nerv Ment Dis 168:753–757

    PubMed  CAS  Google Scholar 

  106. Wilkinson TJ, Begg EJ, Winter AC, Sainsbury R (1999) Incidence and risk factors for hyponatraemia following treatment with fluoxetine or paroxetine in elderly people. Br J Clin Pharmacol 47:211–217

    PubMed  CAS  Google Scholar 

  107. Wiltfang J, Nolte W, Weissenborn K, Kornhuber J, Rüther E (1998) Psychiatric aspects of portal-systemic encephalopathy. Metab Brain Dis 13:379–389

    PubMed  CAS  Google Scholar 

Literatur

  1. Adams SG Jr, Dammers PM, Saia TL, Brantley PJ, Gaydos GR (1994) Stress, depression, and anxiety predict average symptom severity and daily symptom fluctuation in systemic lupus erythematosus. J Behav Med 17:459–477

    PubMed  Google Scholar 

  2. Aikens JE, Reinecke MA, Pliskin NH, Fischer JS, Wiebe JS, McCracken LM, Taylor JL (1999) Assessing depressive symptoms in multiple sclerosis: is it necessary to omit items from the original Beck Depression Inventory? J Behav Med 22:127–142

    PubMed  CAS  Google Scholar 

  3. Andrews NJ, Farrington CP, Cousens SN, Smith PG, Ward H, Knight RS, Ironside JW, Will RG (2000) Incidence of variant Creutzfeldt-Jakob disease in the UK. Lancet 356 (9228):481–482

    PubMed  CAS  Google Scholar 

  4. Arnett FC, Reveille JD, Moutsopoulos HM, Georgescu L, Elkon KB (1996) Ribosomal P autoantibodies in systemic lupus erythematosus. Frequencies in different ethnic groups and clinical and immunogenetic associations. Arthritis Rheum 39:1833–1839

    PubMed  CAS  Google Scholar 

  5. Bakshi R, Shaikh ZA, Miletich RS, Czarnecki D, Dmochowski J, Henschel K, Janardhan V, Dubey N, Kinkel PR (2000) Fatigue in multiple sclerosis and its relationship to depression and neurologic disability. Mult Scler 6:181–185

    PubMed  CAS  Google Scholar 

  6. Bakshi R, Czarnecki D, Shaikh ZA, Priore RL, Janardhan V, Kaliszky Z, Kinkel PR (2000) Brain MRI lesions and atrophy are related to depression in multiple sclerosis. Neuroreport 11:1153–1158

    PubMed  CAS  Google Scholar 

  7. Barak Y, Ur E, Achiron A (1999) Moclobemide treatment in multiple sclerosis patients with comorbid depression: an open-label safety trial. J Neuropsychiatry Clin Neurosci 11:271–273

    PubMed  CAS  Google Scholar 

  8. Barkhof F, Frequin STFM, Hommes OR, Lamers K, Scheltens P, van Geel WJA, Valk J (1992) A correlative triad of galoinium-DPTA MRI, EDSS, and CSF-MBP in relapsing multiple sclerosis patients treated with high-dose intravenous methylprednisolone. Neurology 42:63–67

    PubMed  CAS  Google Scholar 

  9. Bateman D, Hilton D, Love S, Zeidler M, Beck J, Collinge J (1995) Sporadic Creutzfeldt-Jakob disease in a 18-year old in the UK. Lancet 346:1155–1156

    PubMed  CAS  Google Scholar 

  10. Becker H (1997) Psychotische Erscheinungsbilder als Erstmanifestation einer multiplen Sklerose? (MS). Psychiatr Prax 24:69–72

    PubMed  CAS  Google Scholar 

  11. Berg D, Supprian T, Thomae J, Warmuth-Metz M, Horowski A, Zeiler B, Magnus T, Rieckmann P, Becker G (2000) Lesion pattern in patients with multiple sclerosis and depression. Mult Scler 6:156–162

    PubMed  CAS  Google Scholar 

  12. Boerner RJ, Kapfhammer HP (1999) Psychopathological changes and cognitive impairment in encephalomyelitis disseminata. Eur Arch Psychiatry Clin Neurosci 249:96–102

    PubMed  CAS  Google Scholar 

  13. Britton TC, Al-Sarraj S, Shaw C, Campbell T, Collinge J (1995) Sporadic Creutzfeldt-Jakob disease in a 16-year old in the UK. Lancet 346:1155

    PubMed  CAS  Google Scholar 

  14. Brown P, Cathala F, Raubertas RF, Gajdusek DC, Castaigne P (1987) The epidemiology of Creutzfeldt-Jakob disease. Neurology 37:895–904

    PubMed  CAS  Google Scholar 

  15. Büchi S, Buddeberg C, Sieber M (1989) Die Bedeutung somatischer und psychosozialer Faktoren für die Krankheitsverarbeitung von Multiple-Sklerose-Kranken. Nervenarzt 60:641–646

    PubMed  Google Scholar 

  16. Carbotte RM, Denburg SD, Denburg JA (1986) Prevalence of cognitive impairment in systemic lupus erythematosus. J Nery Ment Dis 174:357–364

    CAS  Google Scholar 

  17. Carbotte RM, Denburg SD, Denburg JA (1995) Cognitive dysfunction in systemic lupus erythematosus is independent of active disease. J Rheumatol 22:863–867

    PubMed  CAS  Google Scholar 

  18. Carlomagno S, Migliaresi S, Ambrosone L, Sannino M, Sanges G, Di Iorio G (2000) Cognitive impairment in systemic lupus erythematosus: a follow-up study. J Neurol 247:273–279

    PubMed  CAS  Google Scholar 

  19. Chin CN, Cheong I, Kong N (1993) Psychiatric disorder in Malaysians with systemic lupus erythematosus. Lupus 2:329–332

    PubMed  CAS  Google Scholar 

  20. Collinge J (2000) Creutzfeldt-Jakob disease and other prion diseases. In: O’Brien J, Ames D, Burns A (eds) Dementia, 2 d edn. Arnold, London, pp 863–875

    Google Scholar 

  21. Curry SL, Levine SB, Corty E, Jones PK, Kurit DM (1994) The impact of systemic lupus erythematosus on women’s sexual functioning. J Rheumatol 21:2254–2260

    PubMed  CAS  Google Scholar 

  22. Da Costa D, Dobkin PL, Pinard L, Fortin PR, Danoff DS, Esdaile JM, Clarke AE (1999) The role of stress in functional disability among women with systemic lupus erythematosus: a prospective study. Arthritis Care Res 12:112–119

    PubMed  CAS  Google Scholar 

  23. Devinsky O, Petito CK, Alonso DR (1988) Clinical and neuropathological findings in systemic lupus erythematosus: The role of vasculitis, heart emboli, and thrombotic thrombocytopenic purpura. Ann Neurol 23:380–384

    PubMed  CAS  Google Scholar 

  24. Diaz-Olavarrieta C, Cummings JL, Velazquez J, Garcia de la Cadena C (1999) Neuropsychiatric manifestations of multiple sclerosis. J Neuropsychiatry Clin Neurosci 11:51–57

    Google Scholar 

  25. Dittmann J, Schüttler R (1992) Bewältigungs-und Kompensationsstrategien bei Patienten mit Enzephalomyelitis disseminata (MS) und bei Patienten mit schizophrenen Psychosen. Rehabilitation 31:98–103

    PubMed  CAS  Google Scholar 

  26. Engler F, Vetter P (1991) Affektive and schizophrene Syndrome bei Multipler Sklerose. Literaturübersicht and Kasuistiken Schweiz. Arch Neurol Psychiatr 142: 367–378

    CAS  Google Scholar 

  27. Falcini F, De Cristofaro MT, Ermini M, Guarnieri M, Massai G, Olmastroni M, Masi A, Pupi A, Meldolesi U (1998) Regional cerebral blood flow in juvenile systemic lupus erythematosus: a prospective SPECT study. Single photon emission computed tomography. J Rheumatol 25:583–588

    PubMed  CAS  Google Scholar 

  28. Fassbender K, Schmidt R, Mossner R, Kischka U, Kuhnen J, Schwartz A, Hennerici M (1998) Mood disorders and dysfunction of the hypothalamic-pituitary-adrenal axis in multiple sclerosis: association with cerebral inflammation. Arch Neurol 55:66–72

    PubMed  CAS  Google Scholar 

  29. Feinstein A (2000) Cognitive dysfunction in multiple sclerosis. In: O’Brien J, Ames D, Burns A (eds) Dementia, 2nd edn. Arnold, London, pp 853–859

    Google Scholar 

  30. Feinstein A, Kartsounis L, Miller D, Youl B, Ron M (1992) Clinically isolated lesions of the type seen in multiple sclerosis followed up: a cognitive, psychiatric and MRI study. J Neurol Neurosurg Psychiatry 55:869–876

    PubMed  CAS  Google Scholar 

  31. Feinstein A, Feinstein K, Gray T, O’Connor P (1997) Prevalence and neurobehavioral correlates of pathological laughing and crying in multiple sclerosis. Arch Neurol 54:1116–1121

    PubMed  CAS  Google Scholar 

  32. Feinstein A, O’Connor P, Gray T, Feinstein K (1999) Pathological laughing and crying in multiple sclerosis: a preliminary report suggesting a role for the prefrontal cortex. Mult Scler 5:69–73

    PubMed  CAS  Google Scholar 

  33. Feinstein A, O’Connor P, Gray T, Feinstein K (1999) The effects of anxiety on psychiatric morbidity in patients with multiple sclerosis. Mult Scler 5:323–326

    PubMed  CAS  Google Scholar 

  34. Felgenhauer K (1990) Psychiatric disorders in the encephalitic form of multiple sclerosis. J Neurol 237:11–18

    PubMed  CAS  Google Scholar 

  35. Filley CM, Heaton RK, Nelson LM, Burks JS, Franklin GM (1989) A comparison of dementia in Alzheimer’s disease and multiple sclerosis. Arch Neurol 46:157–161

    PubMed  CAS  Google Scholar 

  36. Fisk JD, Morehouse SA, Brown MG, Skedgel C, Murray TJ (1998) Hospital-based psychiatric service utilization and morbidity in multiple sclerosis. Can J Neurol Sci 25:230–235

    PubMed  CAS  Google Scholar 

  37. Frank C (1985) Psychische Veränderungen bei Multipler Sklerose. Wien med Wschr 135:12–17

    PubMed  CAS  Google Scholar 

  38. Futrell N, Schultz LR, Millikan C (1992) Central nervous system disease in patients with systemic lupus erythematosus. Neurology 42:1649–1659

    PubMed  CAS  Google Scholar 

  39. Galeazzi M, Annunziata P, Sebastiani GD, Bellisai F, Campanella V, Ferrara GB, Font J, Houssiau F, Passiu G, De Ramon Garrido E, Fernandez-Nebro A, Bracci L, Scorza R, Puddu P, Jedryka-Goral A, Smolen J, Tincani A, Carcassi C, Morozzi G, Marcolongo R (2000) Anti-ganglioside antibodies in a large cohort of European patients with systemic lupus erythematosus: clinical, serological, and HLA class II gene associations. European Concerted Action on the Immunogenetics of SLE. J Rheumatol 27:135–141

    PubMed  CAS  Google Scholar 

  40. Georgescu L, Mevorach D, Arnett FC, Reveille JD, Elkon KB (1997) Anti-P antibodies and neuropsychiatric lupus erythematosus. Ann NY Acad Sci 823:263–269

    PubMed  CAS  Google Scholar 

  41. Gibbs CJ Jr, Gajdusek DC, Asher DM, Alpers MP, Beck E, Daniel PM, Matthews WB (1968) Creutzfeldt-Jakob disease (sponiform encephalopathy): transmission to the chimpanzee. Science 161:388–389

    PubMed  Google Scholar 

  42. Giraud P, Perret-Liaudet A, Biacabe AG, Deslys JP, Laplanche JL, Chazot G, Kop N (2000) Maladie de Creutzfeldt-Jakob non familiale certaine: etude de 53 observations. Rev Neurol (Paris) 156:616–621

    CAS  Google Scholar 

  43. Glanz BI, Slonim D, Urowitz MB, Gladman DD, Gough J, MacKinnon A (1997) Pattern of neuropsychologic dysfunction in inactive systemic lupus erythematosus. Neuropsychiatry Neuropsychol Behav Neurol 10:232–238

    PubMed  CAS  Google Scholar 

  44. Griffey RH, Brown MS, Bankhurst AD, Sibbitt RR, Sibbitt WL Jr (1990) Depletion of high-energy phosphates in the central nervous system of patients with systemic lupus erythematosus, as determined by phosphorus-31 nuclear magnetic resonance spectroscopy. Arthritis Rheum 33:827–833

    PubMed  CAS  Google Scholar 

  45. Hakim EA, Bakheit AM, Bryant TN, Roberts MW, McIntosh-Michaelis SA, Spackman AJ, Martin JP, McLellan DL (2000) The social impact of multiple sclerosis - a study of 305 patients and their relatives. Disabil Rehabil 22:288–293

    PubMed  CAS  Google Scholar 

  46. Hampel H, Kotter HU, Padberg F, Korschenhausen DA, Möller HJ (1999) Oligoclonal bands and blood - cerebrospinal-fluid barrier dysfunction in a subset of patients with Alzheimer disease: comparison with vascular dementia, major depression, and multiple sclerosis. Alzheimer Dis Assoc Disord 13:9–19

    PubMed  CAS  Google Scholar 

  47. Hanly JG, Walsh NM, Sangalang V (1992) Brain pathology in systemic lupus erythematosus. J Rheumatol 19:732–741

    PubMed  CAS  Google Scholar 

  48. Hanly JG, Walsh NM, Fisk JD, Eastwood B, Hong C, Sherwood G, Jones JV, Jones E, Elkon K (1993) Cognitive impairment and autoantibodies in systemic lupus erythematosus. Br J Rheumatol 32:291–296

    PubMed  CAS  Google Scholar 

  49. Hanly JG, Fisk JD, Sherwood G, Eastwood B (1994) Clinical course of cognitive dysfunction in systemic lupus erythematosus. J Rheumatol 21:1825–1831

    PubMed  CAS  Google Scholar 

  50. Hay EM, Black D, Huddy A, Creed F, Tomenson B, Bernstein RM, Holt PJ (1992) Psychiatric disorder and cognitive impairment in systemic lupus erythematosus. Arthritis Rheum 35:411–416

    PubMed  CAS  Google Scholar 

  51. Hay EM, Huddy A, Black D, Mbaya P, Tomenson B, Bernstein RM, Lennox Holt PJ, Creed F (1994) A prospective study of psychiatric disorder and cognitive function in systemic lupus erythematosus. Ann Rheum Dis 53:298–303

    PubMed  CAS  Google Scholar 

  52. Hein T, Hopfenmüller W (2000) Hochrechnung der Zahl an Multiple Sklerose erkrankten Patienten in Deutschland. Nervenarzt 71:288–294

    PubMed  CAS  Google Scholar 

  53. Hopkinson ND, Doherty M, Powell RJ (1993) The prevalence and incidence of systemic lupus erythematosus in Nottingham, UK, 1989–1990. Br J Rheumatol 32: 110–115

    PubMed  CAS  Google Scholar 

  54. Hopkinson ND, Doherty M, Powell RJ (1994) Clinical features and race-specific incidence/prevalence rates of systemic lupus erythematosus in a geographically complete cohort of patients. Ann Rheum Dis 53:675–680

    PubMed  CAS  Google Scholar 

  55. Hugo FJ, Halland AM, Spangenberg JJ, Whitelaw DA, Rickman RC, Hewlett RH, Reid J, Maritz JS, Emsley RA (1996) DSM-III-R classification of psychiatric symptoms in systemic lupus erythematosus. Psychosomatics 37:262–269

    PubMed  CAS  Google Scholar 

  56. Hutchinson GA, Nehall JE, Simeon DT (1996) Psychiatric disorders in Systemic Lupus Erythematosus. West Indian Med J 45:48–50

    PubMed  CAS  Google Scholar 

  57. Isshi K, Hirohata S (1998) Differential roles of the anti-ribosomal P antibody and antineuronal antibody in the pathogenesis of central nervous system involvement in systemic lupus erythematosus. Arthritis Rheum 41:1819–1827

    PubMed  CAS  Google Scholar 

  58. Iverson GL, Anderson KW (1994) The etiology of psychiatric symptoms in patients with systemic lupus erythematosus. Scand J Rheumatol 23:277–282

    PubMed  CAS  Google Scholar 

  59. Jacobsen S, Petersen J, Ullman S, Junker P, Voss A, Rasmussen JM, Tarp U, Poulsen LH, van Overeem Hansen G, Skaarup B, Hansen TM, Podenphant J, Halberg P (1999) Mortality and causes of death of 513 Danish patients with systemic lupus erythematosus. Scand J Rheumatol 28:75–80

    PubMed  CAS  Google Scholar 

  60. Johanet C, Andre C, Sibilia J, Baquey A, Oksman F, San Marco M, Humbel RL, Taillefer MF, Chretien P, Escande A, Cohen J, Chevailler A, Monier JC, Goetz J (2000) Signification clinique des anticorps antiribosomes. Groupe d’etude autoimmunite (GEAI). Rev Med Interne 21:510–516

    PubMed  CAS  Google Scholar 

  61. Jonsson H, Nived 0, Sturfelt G, Silman A (1990) Estimating the incidence of systemic lupus erythematosus in a defined population using multiple sources of retrieval. Br J Rheumatol 29:185–188

    PubMed  CAS  Google Scholar 

  62. Kao CH, Ho YJ, Lan JL, Changlai SP, Liao KK, Chieng PU (1999) Discrepancy between regional cerebral blood flow and glucose metabolism of the brain in systemic lupus erythematosus patients with normal brain magnetic resonance imaging findings. Arthritis Rheum 42:61–68

    PubMed  CAS  Google Scholar 

  63. Kenealy PM, Beaumont GJ, Lintern T, Murrell R (2000) Autobiographical memory, depression and quality of life in multiple sclerosis. J Clin Exp Neuropsychol 22:125–131

    PubMed  CAS  Google Scholar 

  64. Kenney K, Brechtel C, Takahashi H, Kurohara K, Anderson P, Gibbs CJ Jr (2000) An enzyme-linked immunosorbent assay to quantify 14–3-3 proteins in the cerebrospinal fluid of suspected Creutzfeldt-Jakob disease patients. Ann Neurol 48:395–398

    PubMed  CAS  Google Scholar 

  65. Kießling WR, Weiss A, Raudies G (1990) Zum Stand der professionellen psychischen Betreuung Multiple-Sklerose-Kranke. Rehabilitation 29:201–203

    PubMed  Google Scholar 

  66. Khan S, Haddad P, Montague L, Summerton C (2000) Systemic lupus erythematosus presenting as mania. Acta Psychiatr Scand 101:406–408

    PubMed  CAS  Google Scholar 

  67. Kovacs JA, Urowitz MB, Gladman DD, Zeman R (1995) The use of single photon emission computerized tomography in neuropsychiatric SLE: a pilot study. J Rheumatol 22:1247–1253

    PubMed  CAS  Google Scholar 

  68. Kushner M, Simonian N (1989) Lupus anticoagulants, anticardiolipin antibodies, and cerebral ischemia. Stroke 20:225–229

    Google Scholar 

  69. Kushner MJ, Tobin M, Fazekas F, Chawluk J, Jamieson D, Freundlich B, Grenell S, Freemen L, Reivich M (1990) Cerebral blood flow variations in CNS lupus. Neurology 40:99–102

    PubMed  CAS  Google Scholar 

  70. Lewis DA, Smith RE (1983) Steroid-induced psychiatric syndromes. A report of 14 cases and a review of the literature. J Affect Disord 5:319–332

    PubMed  CAS  Google Scholar 

  71. Lin WY, Wang SJ, Yen TC, Lan JL (1997) Technetium-99m-HMPAO brain SPECT in systemic lupus erythematosus with CNS involvement. J Nucl Med 38:11121115

    Google Scholar 

  72. McCracken LM, Semenchuk EM, Goetsch VL (1995) Cross-sectional and longitudinal analyses of coping responses and health status in persons with systemic lupus erythematosus. Behav Med 20:179–187

    PubMed  CAS  Google Scholar 

  73. McIntosh-Michaelis SA, Wilkinson SM, Diamond ID, McLellan DL, Martin JP, Spackman AJ (1991) The prevalence of cognitive impairment in a community survey of multiple sclerosis. Br J Clin Psychol 30:333–348

    PubMed  Google Scholar 

  74. McLean BN (1998) Neurological involvement in systemic lupus erythematosus. Curr Opin Neurol 11:247–251

    PubMed  CAS  Google Scholar 

  75. Meyendorf R, Förster C (1973) Das klinische Bild idiopathischer psychoorganischer Hirnsyndrome im Presenium (Jakob-Creutzfeldt-Syndrom-„spongiöse Enzephalopathie“). Arch Psychiat Nervenkr 218:1–40

    PubMed  CAS  Google Scholar 

  76. Miguel EC, Pereira RM, Pereira CA, Baer L, Gomes RE, de Sa LC, Hirsch R, de Barros NG, de Navarro JM, Gentil V (1994) Psychiatric manifestations of systemic lupus erythematosus: clinical features, symptoms, and signs of central nervous system activity in 43 patients. Medicine 73:224–232

    PubMed  CAS  Google Scholar 

  77. Möller A, Wiedemann G, Rhode, Backmund H, Sonntag A (1994) Correlations of cognitive impairment and depressive mood disorder in multiple sclerosis. Acta Psychiat Scand 89:117–121

    PubMed  Google Scholar 

  78. Mohr DC, Goodkin DE, Gatto N, Van der Wende J (1997) Depression, coping and level of neurological impairment in multiple sclerosis. Mult Scler 3:254–258

    PubMed  CAS  Google Scholar 

  79. Mohr DC, Likosky W, Dwyer P, Van Der Wende J, Boudewyn AC, Goodkin DE (1999) Course of depression during the initiation of interferon beta-la treatment for multiple sclerosis. Arch Neurol 56:1263–1265

    PubMed  CAS  Google Scholar 

  80. Multiple Sklerose-Therapie-Konsensus-Gruppe (MSTKG) (2000) Immunomodulatorische Stufentherapie der multiplen Sklerose. Nervenarzt 71:371–386

    Google Scholar 

  81. Multiple Sklerose-Therapie-Konsensus-Gruppe (MSTKG) (2001) Immunomodulatorische Stufentherapie der multiplen Sklerose. 1. Ergänzung Dezember 2000. Nervenarzt 72:150–157

    Google Scholar 

  82. Munoz-Malaga A, Anglada JC, Paez M, Giron JM, Barrera A (1999) Psicosis como manifestacion inicial de lupus eritematoso sistemico: valor de la prueba de la banda lupica frente a los anticuerpos antirribosomales. Rev Neurol 28:779781

    Google Scholar 

  83. Noy S, Achiron A, Gabbay U, Barak Y, Rotstein Z, Laor N, Sarova-Pinhas I (1995) A new approach to affective symptoms in relapsing-remitting multiple sclerosis. Compr Psychiatry 36:390–395

    PubMed  CAS  Google Scholar 

  84. Nyenhuis DL, Rao SM, Zajecka JM, Luchetta T, Bernardin L, Garron DC (1995) Mood disturbance versus other symptoms of depression in multiple sclerosis. J Int Neuropsychol Soc 1:291–296

    PubMed  CAS  Google Scholar 

  85. Oentrich W, Dose T, Friedmann D, Haupts M, Haller P, Hartung HP, Walther EU, König N, Schröder G, Stürzebecher CS (2001) Interferon-/ilb (Betaferon®) bei Patienten mit schubförmiger-remittierender Multipler Sklerose. Ergebnisse einer prospektiven, multizentrischen Verlaufsbeobachtung. Nervenarzt 72:286–292

    PubMed  CAS  Google Scholar 

  86. Omdal R, Husby G, Mellgren SI (1995) Mental health status in systemic lupus erythematosus. Scand J Rheumatol 24:142–145

    PubMed  CAS  Google Scholar 

  87. Poser CM (2000) The pathogenesis of multiple sclerosis: a commentary. Clin Neurol Neurosurg 102:191–194

    PubMed  CAS  Google Scholar 

  88. Poser CM, Paty DW, Scheinberg L, McDonald WI, Davis FA, Ebers GC, Johnson KP, Sibley WA, Silberberg DH, Tourtellotte WW (1983) New diagnostic criteria for multiple sclerosis: guidelines for research protocols. Ann Neurol 13:227–231

    PubMed  CAS  Google Scholar 

  89. Poser CM, Brinar VV (2001) Diagnostic criteria for multiple sclerosis. Clin Neu-rol Neurosurg. 103:1–11

    CAS  Google Scholar 

  90. Poser S, Kurtzke JF, Poser W, Schlaf G (1989) Survival in multiple sclerosis. J Clin Epidemiol 42:159–168

    PubMed  CAS  Google Scholar 

  91. Rao SM, Leo GJ, Ellington L, Nauertz T, Berhardin L, Unverzagt F (1991) Cognitive dysfunction in multiple sclerosis. I. Frequency, pattern, and prediction. Neurology 41:685–691

    PubMed  CAS  Google Scholar 

  92. Reiff A, Miller J, Shaham B, Bernstein B, Szer IS (1997) Childhood central nervous system lupus; longitudinal assessment using single photon emission computed tomography. J Rheumatol 24:2461–2465

    PubMed  CAS  Google Scholar 

  93. Ritter G (1984) Psychosomatische Aspekte der Multiplen Sklerose-Verlauf und Bewältigung einer chronischen Krankheit. Akt Neurol 11:69–72

    Google Scholar 

  94. Rivest C, Lew RA, Welsing PM, Sangha O, Wright EA, Roberts WN, Liang MH, Karlson EW (2000) Association between clinical factors, socioeconomic status, and organ damage in recent onset systemic lupus erythematosus. J Rheumatol 27:680–684

    PubMed  CAS  Google Scholar 

  95. Rubio Valladolid G, Gil Aguado A, Balsa Criado A, Ferre Navarrete F, Moreno de la Santa C, Martin Mola E, Garcia Tobaruela A, Lavilla Uriol P (1998) Prevalencia de trastornos psiquiatricos y estado psicopatologico en pacientes con lupus eritematoso sistemico. Rev Clin Esp198:61–65

    Google Scholar 

  96. Rumpf HJ, Wessel K (1995) Copingmuster und Adaptivität bei multipler Sklerose. Nervenarzt 66:624–629

    PubMed  CAS  Google Scholar 

  97. Sabatini U, Pozzilli C, Pantano P, Koudriavtseva T, Padovani A, Millefiorini E, Di Biasi C, Gualdi GF, Salvetti M, Lenzi GL (1996) Involvement of the limbic system in multiple sclerosis patients with depressive disorders. Biol Psychiatry 39:970–975

    PubMed  CAS  Google Scholar 

  98. Sachse C, Luthke K, Hartung K, Fricke M, Liedvogel B, Kalden JR, Peter HH, Lakomek HJ, Henkel E, Deicher H (1995) Significance of antibodies to cardiolipin in unselected patients with systemic lupus erythematosus: clinical and laboratory associations. The SLE Study Group. Rheumatol Int 15:23–29

    PubMed  CAS  Google Scholar 

  99. Sailer M, Burchert W, Ehrenheim C, Smid HG, Haas J, Wildhagen K, Wurster U, Deicher H (1997) Positron emission tomography and magnetic resonance imaging for cerebral involvement in patients with systemic lupus erythematosus. J Neurol 244:186–193

    PubMed  CAS  Google Scholar 

  100. Schiffer RB, Wineman NM (1990) Antidepressant pharmacotherapy of depression associated with multiple sclerosis. Am J Psychiatry 147:1493–1497

    PubMed  CAS  Google Scholar 

  101. Schifferdecker M, Krahl A, Krekel NO (1995) Psychosen bei multipler Sklerose - eine Neubewertung. Fortschr Neurol Psychiatr 63:310–319

    PubMed  CAS  Google Scholar 

  102. Schröter A, Zerr I, Henkel K, Tschampa HJ, Finkenstaedt M, Poser S (2000) Magnetic resonance imaging in the clinical diagnosis of creutzfeldt-jakob disease. Arch Neurol 57:1751–1757

    PubMed  Google Scholar 

  103. Scott TF, Nussbaum P, McConnell H, Brill P (1997) Measurement of treatment response to sertraline in depressed multiple sclerosis patients using the Carroll scale. Neurol Res 17:421–422

    Google Scholar 

  104. Shortall E, Isenberg D, Newman SP (1995) Factors associated with mood and mood disorders in SLE. Lupus 4:272–279

    PubMed  CAS  Google Scholar 

  105. Sibbitt WL Jr, Haseler LJ, Griffey RR, Friedman SD, Brooks WM (1997) Neurometabolism of active neuropsychiatric lupus determined with proton MR spectroscopy. Am J Neuroradiol 18:1271–1277

    PubMed  Google Scholar 

  106. Sibley JT, Olszynski WP, Decoteau WE, Sundaram MB (1992) The incidence and prognosis of central nervous system disease in systemic lupus erythematosus. J Rheumatol 19:47–52

    PubMed  CAS  Google Scholar 

  107. Spezialetti R, Bluestein HG, Peter JB, Alexander EL (1993) Neuropsychiatric disease in Sjögren’s syndrome: anti-ribosomal P and anti-neuronal antibodies. Am J Med 95:153–160

    PubMed  CAS  Google Scholar 

  108. Stahl-Hallengren C, Jonsen A, Nived O, Sturfelt G (2000) Incidence studies of systemic lupus erythematosus in Southern Sweden: increasing age, decreasing frequency of renal manifestations and good prognosis. J Rheumatol 27:685–691

    PubMed  CAS  Google Scholar 

  109. Steinlin MI, Blaser SI, Gilday DL, Eddy AA, Logan WJ, Laxer RM, Silverman ED (1995) Neurologic manifestations of pediatric systemic lupus erythematosus. Pediatr Neurol 13:191–197

    PubMed  CAS  Google Scholar 

  110. Stenager EN, Koch-Henriksen N, Stenager E (1996) Risk factors for suicide in multiple sclerosis. Psychother Psychosom 65:86–90

    PubMed  CAS  Google Scholar 

  111. Stimmler MM, Coletti PM, Quismorio FP Jr (1993) Magnetic resonance imaging of the brain in neuropsychiatric systemic lupus erythematosus. Semin Arthritis Rheum 22:335–349

    PubMed  CAS  Google Scholar 

  112. Swaak AJ, van den Brink HG, Smeenk RJ, Manger K, Kalden JR, Tosi S, Marchesoni A, Domljan Z, Rozman B, Logar D, Pokorny G, Kovacs L, Kovacs A, Vlachoyiannopoulos PG, Moutsopoulos HM, Chwalinska-Sadowska H, Dratwianka B, Kiss E, Cikes N, Branimir A, Schneider M, Fischer R, Bombardieri S, Mosca M, Smolen JS (1999) Systemic lupus erythematosus: clinical features in patients with a disease duration of over 10 years, first evaluation. Rheumatology (Oxford) 38:953–958

    CAS  Google Scholar 

  113. Swirsky-Sacchetti T, Mitchell DR, Seward J, Gonzales C, Lublin F, Knobler R, Field HL (1992) Neuropsychological and structural brain lesions in multiple sclerosis: A regioríal analysis. Neurology 42:1291–1295

    PubMed  CAS  Google Scholar 

  114. Szer IS, Miller JH, Rawlings D, Shaham B, Bernstein B (1993) Cerebral perfusion abnormalities in children with central nervous system manifestations of lupus detected by single photon emission computed tomography. J Rheumatol 20: 2143–2148

    PubMed  CAS  Google Scholar 

  115. Teh LS, Hay EM, Amos N, Black D, Huddy A, Creed F, Bernstein RM, Holt PJ, Williams BD (1993) Anti-P antibodies are associated with psychiatric and focal cerebral disorders in patients with systemic lupus erythematosus. Br J Rheumatol 32:287–290

    PubMed  CAS  Google Scholar 

  116. Thompson AJ, Miller D, Youl B, MacManus D, Moore S, Kingsley D, Kendall B, Feinstein A, McDonald WI (1992) Serial gadolinium-enhanced MRI in relapsing/ remitting multiple sclerosis of varying disease duration. Neurology 42:60–63

    PubMed  CAS  Google Scholar 

  117. Uramoto KM, Michet CJ Jr, Thumboo J, Sunku J, O’Fallon WM, Gabriel SE (1999) Trends in the incidence and mortality of systemic lupus erythematosus, 1950–1992. Arthritis Rheum 42:46–50

    PubMed  CAS  Google Scholar 

  118. Utset TO, Golden M, Siberry G, Kiri N, Crum RM, Petri M (1994) Depressive symptoms in patients with systemic lupus erythematosus: association with central nervous system lupus and Sjögren’s syndrome. J Rheumatol 21:2039–2045

    PubMed  CAS  Google Scholar 

  119. Van Horn G, Arnett FC, Dimachkie MM (1996) Reversible dementia and chorea in a young woman with the lupus anticoagulant. Neurology 46:1599–1603

    PubMed  CAS  Google Scholar 

  120. Van Oosten BW, Truyen L, Barkhof F, Polman CH (1995) Multiple sclerosis therapy. A practical guide. Drugs 49:200–212

    PubMed  CAS  Google Scholar 

  121. Vargas-Alarcon G, Yamamoto-Furusho JK, Zuniga J, Canoso R, Granados J (1997) HLA-DR7 in association with chlorpromazine-induced lupus anticoagulant (LA). J Autoimmun 10:579–583

    PubMed  CAS  Google Scholar 

  122. Verity CM, Nicoll A, Will RG, Devereux G, Stellitano L (2000) Variant Creutzfeldt-Jakob disease in UK children: a national surveillance study. Lancet 356 (9237):1224–1227

    PubMed  CAS  Google Scholar 

  123. Voss A, Green A, Junker P (1998) Systemic lupus erythematosus in Denmark: clinical and epidemiological characterization of a county-based cohort. Scand J Rheumatol 27:98–105

    PubMed  CAS  Google Scholar 

  124. Wang B, Gladman DD, Urowitz MB (1998) Fatigue in lupus is not correlated with disease activity. J Rheumatol 25:892–895

    PubMed  CAS  Google Scholar 

  125. Ward MM, Lotstein DS, Bush TM, Lambert RE, van Vollenhoven R, Neuwelt CM (1999) Psychosocial correlates of morbidity in women with systemic lupus erythematosus. J Rheumatol 26:2153–2158

    PubMed  CAS  Google Scholar 

  126. Watanabe T, Sato T, Uchiumi T, Arakawa M (1996) Neuropsychiatric manifestations in patients with systemic lupus erythematosus: diagnostic and predictive value of longitudinal examination of anti-ribosomal P antibody. Lupus 5:178–183

    PubMed  CAS  Google Scholar 

  127. Weiner SM, Otte A, Schumacher M, Klein R, Gutfleisch J, Brink I, Otto P, Nitzsche EU, Moser E, Peter HH (2000) Diagnosis and monitoring of central nervous system involvement in systemic lupus erythematosus: value of F-18 fluorodeoxyglucose PET. Ann Rheum Dis 59:377–385

    PubMed  CAS  Google Scholar 

  128. Wekking EM (1993) Psychiatric symptoms in systemic lupus erythematosus: an update. Psychosom Med 55:219–228

    PubMed  CAS  Google Scholar 

  129. Wiendl H, Neuhaus O, Kappos L, Hohlfeld R (2000) Multiple Sklerose. Aktuelle Übersicht zu fehlgeschlagenen and abgebrochenen Therapiestudien. Nervenarzt 71:597–610

    PubMed  CAS  Google Scholar 

  130. Windl O, Giese A, Schulz-Schaeffer W, Zerr I, Skworc K, Arendt S, Oberdieck C, Bodemer M, Poser S, Kretzschmar HA (1999) Molecular genetics of human prion diseases in Germany. Hum Genet 105:244–252

    PubMed  CAS  Google Scholar 

  131. Zerr I, Pocchiari M, Collins S, Brandel JP, de Pedro Cuesta J, Knight RS, Bernheimer H, Cardone F, Delasnerie-Laupretre N, Cuadrado Corrales N, Ladogana A, Bodemer M, Fletcher A, Awan T, Ruiz Bremon A, Budka H, Laplanche JL, Will RG, Poser S (2000) Analysis of EEG and CSF 14–3-3 proteins as aids to the diagnosis of creutzfeldt-jakob disease. Neurology 55:811–815

    PubMed  CAS  Google Scholar 

  132. Zimmermann C, Walther EU, Goebels N, Lienert C, Kappos L, Hartung HP, Hohlfeld R (1999) Interferon ß-lb zur Behandlung der sekundär chronisch progrdienten multiplen Sklerose. Nervenarzt 70:759–763

    PubMed  CAS  Google Scholar 

  133. Zorzon M, Zivadinov R, Bosco A, Bragadin LM, Moretti R, Bonfigli L, Morassi P, Iona LG, Cazzato G (1999) Sexual dysfunction in multiple sclerosis: a case-control study. I. Frequency and comparison of groups. Mult Scler 5:418–427

    PubMed  CAS  Google Scholar 

Literatur

  1. Adachi N, Onuma T, Nishiwaki S, Murauchi S, Akanuma N, Ishida S, Takei N (2000) Inter-ictal and post-ictal psychoses in frontal lobe epilepsy: a retrospective comparison with psychoses in temporal lobe epilepsy. Seizure 9:328–335

    PubMed  CAS  Google Scholar 

  2. Barczak P, Edmunds E, Betts T (1988) Hypomania following complex partial seizures. A report of three cases. Br J Psychiatry 152:137–139

    PubMed  CAS  Google Scholar 

  3. Bazire S (2000) Psychotropic drug directory 2000. Mark Allen Publishing, Wilts

    Google Scholar 

  4. Blank R (1990) Antikonvulsiva and ihre psychischen Wirkungen - eine Übersicht. Fortschr Neurol Psychiatr 58:19–32

    PubMed  CAS  Google Scholar 

  5. Blankenhorn V (1992) Psychosoziale Aspekte. In: Möller AA, Fröscher W (Hrsg) Psychische Störungen bei Epilepsie. Thieme, Stuttgart, S 139–147

    Google Scholar 

  6. Blumer D (1995) Personality disorders in epilepsy. In: Ratey JJ (ed) Neuropsychiatry and personality disorders. Blackwell Science, Oxford, pp 230–263

    Google Scholar 

  7. Blumer D (1999) Evidence supporting the temporal lobe epilepsy personality syndrome. Neurology 53 (5 Suppl 2): S 9–12

    Google Scholar 

  8. Blumer D, Wakhlu S, Montouris G, Wyler AR (2000) Treatment of the interictal psychoses. J Clin Psychiatry 61:110–122

    PubMed  CAS  Google Scholar 

  9. Bogdanovic MD, Mead SH, Duncan JS (2000) Aggressive behaviour at a residential epilepsy centre. Seizure 9:58–64

    PubMed  CAS  Google Scholar 

  10. Bredkjaer SR, Mortensen PB, Parnas J (1998) Epilepsy and non-organic non-affective psychosis. National epidemiologic study. Br J Psychiatry 172:235–238

    PubMed  CAS  Google Scholar 

  11. Bruton CJ, Stevens JR, Frith CD (1994) Epilepsy, psychosis, and schizophrenia: clinical and neuropathologic correlations. Neurology 44:34–42

    PubMed  CAS  Google Scholar 

  12. Cascino GD (1993) Nonconvulsive status epilepticus in adults and children. Epilepsia 34 (Suppl 1):21–28

    Google Scholar 

  13. Commission on classification and terminology of the international league against epilepsy (1981) Proposal for revised clinical and electroencephalographic classification of epileptic seizures. Epilepsia 22:489–501

    Google Scholar 

  14. Commission on classification and terminology of the international league against epilepsy (1989) Proposal for revised classification of epilepsy and epileptic syndromes. Epilepsia 30:389–399

    Google Scholar 

  15. Conlon P, Trimble MR, Rogers D (1990) A study of epileptic psychosis using magnetic resonance imaging. Br J Psychiatry 156:231–235

    PubMed  CAS  Google Scholar 

  16. Demerdash A, Shaalan M, Midani A, Kamel F, Bahri M (1991) Sexual behavior of a sample of females with epilepsy. Epilepsia 32:82–85

    PubMed  CAS  Google Scholar 

  17. Devinsky O, Abramson H, Alper K, FitzGerald LS, Perrine K, Calderon J, Luciano D (1995) Postictal psychosis: a case control series of 20 patients and 150 controls. Epilepsy Res 20:247–253

    PubMed  CAS  Google Scholar 

  18. Devinsky O, Najjar S (1999) Evidence against the existence of a temporal lobe epilepsy personality syndrome. Neurology 53(5 Suppl 2): S13–25

    PubMed  CAS  Google Scholar 

  19. Diehl LW (1992) Epidemiologie psychischer Störungen. In: Möller AA, Fröscher W (Hrsg) Psychische Störungen bei Epilepsie. Thieme, Stuttgart, S 6–10

    Google Scholar 

  20. Dilling H, Mombour W, Schmidt MH (1994) Internationale Klassifikation psychischer Störungen. Forschungskriterien. Huber, Bern

    Google Scholar 

  21. Dilling H, Mombour W, Schmidt MH (2000) Internationale Klassifikation psychischer Störungen. ICD-10 Kapitel V (F) Klinisch-diagnostische Leitlinien, 3. Aufl. Huber, Bern

    Google Scholar 

  22. Dodrill CB (1986) Correlates of generalized tonic-clonic seizures with intellectual, neuropsychological, emotional and social function in patients with epilepsy. Epilepsia 27:399–411

    PubMed  CAS  Google Scholar 

  23. Dodrill CB (1992) Psychiatrische und neuropsychologische Störungen in Beziehung zu verschiedenen Krankheitsvariablen in der Epilepsie. In: Möller AA, Fröscher W (Hrsg) Psychische Störungen bei Epilepsie. Thieme, Stuttgart, S 123–130

    Google Scholar 

  24. Dongier S (1959) Statistical study of clinical and electroencephalographic manifestations of 536 psychotic episodes occuring in 916 epileptics between clinical seizures. Epilepsia 1:117

    PubMed  CAS  Google Scholar 

  25. Ettinger AB, Weisbrot DM, Nolan EE, Gadow KD, Vitale SA, Andriola MR, Lenn NJ, Novak GP, Hermann BP (1998) Symptoms of depression and anxiety in pediatric epilepsy patients. Epilepsia 39:595–599

    PubMed  CAS  Google Scholar 

  26. Fiordelli E, Beghi E, Bogliun G, Crespi V (1993) Epilepsy and psychiatric disturbance. A cross-sectional study. Br J Psychiatry 163:446–450

    PubMed  CAS  Google Scholar 

  27. Fröscher W (1992) Klassifikation und Nomenklatur epileptischer Anfälle und epileptischer Syndrome. In: Möller AA, Fröscher W (Hrsg) Psychische Störungen bei Epilepsie), Thieme, Stuttgart, S 1–5

    Google Scholar 

  28. Fröscher W (1992) Wechselwirkungen antikonvulsiver Behandlung mit Psychopharmaka. In: Möller AA, Fröscher W (Hrsg) Psychische Störungen bei Epilepsie. Thieme, Stuttgart, S 116–122

    Google Scholar 

  29. Fröscher W, Rauber A, Wolfersdorf M (1992) Antikonvulsive Behandlung. In: Möller AA, Fröscher W (Hrsg) Psychische Störungen bei Epilepsie. Thieme, Stuttgart, S 107–115

    Google Scholar 

  30. Gram L (1990) Epileptic seizures and syndromes. Lancet 336 (8708):161–163

    PubMed  CAS  Google Scholar 

  31. Greil W, Ludwig-Mayerhofer W, Erazo N, Engel RR, Czernik A, Giedtke H, Müller-Oerlinghausen B, Osterheider M, Rudolf GAE, Sauer H, Tegeler J, Wetterling T (1997) Lithium vs carbamazepine in the maintanence treatment of schizoaffective disorder: a randomised study. Eur Arch Psychiatry Clin Neurosci 247:42–50

    PubMed  CAS  Google Scholar 

  32. Greil W, Ludwig-Mayerhofer W, Erazo N, Schöchlin C, Schmidt S, Engel RR, Czernik A, Giedtke H, Müller-Oerlinghausen B, Osterheider M, Rudolf GAE, Sauer H, Tegeler J, Wetterling T (1997) Lithium versus carbamazepine in the maintenance treatment of bipolar disorders - a randomised study. J Affect Dis 43:151–161

    PubMed  CAS  Google Scholar 

  33. Hausser-Hauw C, Bancaud J (1987) Gustatory hallucinations in epileptic seizures. Electrophysiological, clinical and anatomical correlates. Brain 110:339–359

    PubMed  Google Scholar 

  34. Hermann BP, Seidenberg M, Bell B (2000) Psychiatric comorbidity in chronic epilepsy: identification, consequences, and treatment of major depression. Epilepsia 41, Suppl 2:31–41

    Google Scholar 

  35. Heuser I, Möller AA (1992) Depression. In: Möller AA, Fröscher W (Hrsg) Psychische Störungen bei Epilepsie. Thieme, Stuttgart, S 37–44

    Google Scholar 

  36. Hunger J (1983) Psychopathologische Untersuchungen zur sogenannten epileptischen Wesensänderung. Fortschr Neurol Psychiat 51:327–341

    PubMed  CAS  Google Scholar 

  37. Hunger J (1992) Persönlichkeitsstörungen bei Epilepsie. In: Möller AA, Fröscher W (Hrsg) Psychische Störungen bei Epilepsie. Thieme, Stuttgart, S 58–63

    Google Scholar 

  38. Jibiki I, Maeda T, Kubota T, Yamaguchi N (1993) 123I-IMP SPECT brain imaging in epileptic psychosis: a study of two cases of temporal lobe epilepsy with schizophrenia-like syndrome. Neuropsychobiology 28:207–211

    Google Scholar 

  39. Kanemoto K, Kawasaki J, Kawai I (1996) Postictal psychosis: a comparison with acute interictal and chronic psychoses. Epilepsia 37:551–556

    PubMed  CAS  Google Scholar 

  40. Kanner AM, Nieto JC (1999) Depressive disorders in epilepsy. Neurology 53 Suppl 2:S26–32

    Google Scholar 

  41. Ketter TA, Post RM, Theodore WH (1999) Positive and negative psychiatric effects of antiepileptic drugs in patients with seizure disorders. Neurology 53(5 Suppl 2): 53–67

    Google Scholar 

  42. Köhler G-K (1975) Epileptische Psychosen. Klassifikationsversuche und EEG-Verlaufsbeobachtungen. Fortschr Neurol Psychiatr 43:99–153

    Google Scholar 

  43. Köhler G-K (1992) Epileptische Psychosen. In: Möller AA, Fröscher W (Hrsg) Psychische Störungen bei Epilepsie. Thieme, Stuttgart, S 70–88

    Google Scholar 

  44. Klosterkötter J (1992) Medikamentöse Behandlung epileptischen Psychosen. In: Möller AA, Fröscher W (Hrsg) Psychische Störungen bei Epilepsie. Thieme, Stuttgart, S 177–181

    Google Scholar 

  45. Klosterkötter J (1993) Epileptische Wesensänderung. In: Schüttler R (Hrsg) Organische Psychosyndrome. Springer, Berlin, S 69–81

    Google Scholar 

  46. Klosterkötter J, Breuer H (1992) Medikamentöse Behandlung psychischer Störungen. In: Möller AA, Fröscher W (Hrsg) Psychische Störungen bei Epilepsie. Thieme, Stuttgart, S 171–176

    Google Scholar 

  47. Kristensen O, Sindrup EH (1979) Psychomotor epilepsy and psychosis. III. Social and psychological correlates. Acta Neurol Scand 59:1–9

    PubMed  CAS  Google Scholar 

  48. Lambert MV, Robertson MM (1999) Depression in epilepsy: etiology, phenomenology, and treatment. Epilepsia 1999; 40 Suppl 10:21–47

    Google Scholar 

  49. Landolt H (1953) Serial electroencephalographaphic investigations during psychotic episodes in epileptic patients and during schizophrenic attacks. In: Lorentz de Haas AM (ed) Lectures on epilepsy. Elsevier, Amsterdam, pp 91–133

    Google Scholar 

  50. Levinson DF, Devinsky O (1999) Psychiatric adverse events during vigabatrin therapy. Neurology 53:1503–1511

    PubMed  CAS  Google Scholar 

  51. Logsdail SJ, Toone BK (1988) Postictal psychosis: A clinical and phenomenological description. Br J Psychiatry 152:246–252

    PubMed  CAS  Google Scholar 

  52. Mace CJ (1993) Epilepsy and schizophrenia. Br J Psychiatry 163:439–445

    PubMed  CAS  Google Scholar 

  53. Manchanda R, Schaefer B, McLachlan RS, Blume WT (1992) Interictal psychiatric morbidity and focus of epilepsy in treatment-refractory patients admitted to an epilepsy unit. Am J Psychiatry 149:1096–1098

    PubMed  CAS  Google Scholar 

  54. Marshall EJ, Syed GM, Fenwick PB, Lishman WA (1993) A pilot study of schizophrenia-like psychosis in epilepsy using single-photon emission computerised tomography. Br J Psychiatry 163:32–36

    PubMed  CAS  Google Scholar 

  55. Meldrum BS (1990) Epileptic seizures and syndromes. Lancet 336 (8709):231–234

    PubMed  CAS  Google Scholar 

  56. Mellers JD, Toone BK, Lishman WA (2000) A neuropsychological comparison of schizophrenia and schizophrenia-like psychosis of epilepsy. Psychol Med 30:325–335

    PubMed  CAS  Google Scholar 

  57. Mendez MF, Doss RC, Taylor JL, Arguello R (1995) Relationship of seizure variables to personality disorders in epilepsy. J Neuropsychiatry Clin Neurosci 5:283–286

    Google Scholar 

  58. Mombour W (1992) Klassifikation psychischer Störungen. In: Möller AA, Fröscher W (Hrsg) Psychische Störungen bei Epilepsie. Thieme, Stuttgart, S 18–27

    Google Scholar 

  59. Morrell MJ (1991) Sexual dysfunction in epilepsy. Epilepsia 32 Suppl 6:S38–45

    Google Scholar 

  60. Panayiotopoulos CP (1994) Elementary visual hallucinations in migraine and epilepsy. J Neurol Neurosurg Psychiatry 57:1371–1374

    PubMed  CAS  Google Scholar 

  61. Perini GI, Tosin C, Carraro C, Bernasconi G, Canevini MP, Canger R, Pellegrini A, Testa G (1996) Interictal mood and personality disorders in temporal lobe epilepsy and juvenile myoclonic epilepsy. J Neurol Neurosurg Psychiatry 61:601–605

    PubMed  CAS  Google Scholar 

  62. Pohlmann-Eden B (2000) Epilepsie. In: Förstl H (Hrsg) Klinische Neuro-Psychiatrie. Thieme, Stuttgart, S 270–297

    Google Scholar 

  63. Rundell JR, Wise MG (1989) Causes of organic mood disorder. J Neuropsychiatry Clin Neurosci 1:398–400

    PubMed  CAS  Google Scholar 

  64. Sachdev P (1998) Schizophrenia-like psychosis and epilepsy: the status of the association. Am J Psychiatry 155:325–336

    PubMed  CAS  Google Scholar 

  65. Savard G, Andermann F, Oliver A, Remillard GM (1991) Postictal psychosis after partial complex seizures: A multiple study. Epilepsia 32:225–231

    PubMed  CAS  Google Scholar 

  66. Saß H, Wittchen H-U, Zaudig M (Hrsg) (2000) Diagnostisches und Statistisches Manual Psychischer Störung DSM-IV, 3. Aufl. Hogrefe, Göttingen

    Google Scholar 

  67. Schachter SC (1999) Antiepileptic drug therapy: general treatment principles and application for special patient populations. Epilepsia. 1999; 40 Suppl 9:20–25

    Google Scholar 

  68. Schmitz EB, Robertson MM, Trimble MR (1999) Depression and schizophrenia in epilepsy: social and biological risk factors. Epilepsy Res 35:59–68

    PubMed  CAS  Google Scholar 

  69. Shorvon SD (1990) Epidemiology, classification, natural course and genetics of epilepsy. Lancet 336:93–96

    PubMed  CAS  Google Scholar 

  70. Shukla GD, Srivastava ON, Katiyar BC (1979) Sexual disturbances in temporal lobe epilepsy: a controlled study. Br J Psychiatry 134:288–292

    PubMed  CAS  Google Scholar 

  71. Stevens JR (1988) Psychiatric aspects of epilepsy. J Clin Psychiatry 49 Supp1:49–57

    Google Scholar 

  72. Strian F (1992) Pathogenese psychischer Störungen - die paroxysmale Angst. In: Möller AA, Fröscher W (Hrsg) Psychische Störungen bei Epilepsie. Thieme, Stuttgart, S 11–17

    Google Scholar 

  73. Strian F (1992) Angstsyndrome. In: Möller AA, Fröscher W (Hrsg) Psychische Störungen bei Epilepsie. Thieme, Stuttgart, S 50–54

    Google Scholar 

  74. Swanson SJ, Rao SM, Grafman J, Salazar AM, Kraft J (1995) The relationship between seizure subtype and interictal personality. Results from the Vietnam Head Injury Study. Brain 118:91–103

    PubMed  Google Scholar 

  75. Tellenbach H (1965) Epilepsie als Anfallsleiden und als Psychose. Über alternative Psychosen paranoider Prägung bei,forcierter Normalisierung’ (Landolt) des Elektroencephalogramms Epileptischer. Nervenarzt 36:190–202

    PubMed  CAS  Google Scholar 

  76. Trimble MR (1988) Psychiatrische und psychologische Aspekte der Epilepsie. In: Kisker KP, Lauter H, Meyer J-E, Müller C, Strömgren E (Hrsg) Organische Psychosen. Springer, Berlin, S 325–363

    Google Scholar 

  77. Trimble MR, Ring HA, Schmitz B (1996) Neuropsychiatric aspects of epilepsy. In: Fogel BS, Schiffer RB, Rao SM (eds) Neuropsychiatry. Williams & Wilkins, Baltimore, pp 771–803

    Google Scholar 

  78. Trimble MR, Rusch N, Betts T, Crawford PM (2000) Psychiatric symptoms after therapy with new antiepileptic drugs: psychopathological and seizure related variables. Seizure 9:249–254

    PubMed  CAS  Google Scholar 

  79. Umbricht D, Degreef G, Barr WB, Lieberman JA, Pollack S, Schaul N (1995) Postictal and chronic psychoses in patients with temporal lobe epilepsy. Am J Psychiatry 152:224–231

    PubMed  CAS  Google Scholar 

  80. Victoroff JI, Benson F, Grafton ST, Engel J, Mazziotta JC (1994) Depression in complex partial seizures. Arch Neurol 51:155–163

    PubMed  CAS  Google Scholar 

  81. Vuilleumier P, Jallon P (1998) Epilepsie et troubles psychiatriques: donnees epidemiologiques. Rev Neurol (Paris) 154:305–317

    CAS  Google Scholar 

  82. Wiegartz P, Seidenberg M, Woodard A, Gidal B, Hermann B (1999) Co-morbid psychiatric disorder in chronic epilepsy: recognition and etiology of depression. Neurology 53 (5 Suppl 2):3–8

    Google Scholar 

  83. Winawer MR, Ottman R, Hauser WA, Pedley TA (2000) Autosomal dominant partial epilepsy with auditory features: defining the phenotype. Neurology 54:2173–2176

    PubMed  CAS  Google Scholar 

  84. Woolley J, Smith S (2001) Lowered seizure threshold on olanzapine. Br J Psychiatry 178:85–86

    PubMed  CAS  Google Scholar 

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Wetterling, T. (2002). Erkrankungen, die zu einer organischen psychischen Störung führen können. In: Organische psychische Störungen. Steinkopff, Heidelberg. https://doi.org/10.1007/978-3-642-57532-7_5

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