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Phytopharmaka VII pp 149–161Cite as

Übersicht zu Interaktionsstudien mit Johanniskrautextrakten

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Zusammenfassung

Obwohl Johanniskrautpräparate weltweit über viele Jahre und in groβer Häufigkeit eingenommen wurden, liegen Berichte zu Arzneimittelwechselwirkungen erst seit kurzem vor [24, 30, 38, 51]. Die zum Teil deutlichen Effekte einer Johanniskrautgabe auf komedizierte Arzneimittel mündeten in eine Vielzahl von Studien, die sich mit der klinischen Relevanz und den zugrundeliegenden Mechanismen der Interaktionen beschäftigten. Der vorliegende Beitrag möchte diese neuen Erkenntnisse und Studienergebnisse zusammenfassen und sowohl über das Spektrum als auch über mögliche Mechanismen der Interaktionen mit Johanniskraut Auskunft geben.

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Authors and Affiliations

  1. Institut für Klinische Pharmakologie, Universitätsklinikum Charité, Humboldt-Universität zu Berlin, Deutschland

    A. Johne, I. Mai, S. Bauer, H. Krüger, G. Arold, E. Störmer, T. Gerloff & I. Roots

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  1. A. Johne
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  2. I. Mai
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Editors and Affiliations

  1. Oranienburger Chaussee 25, 13465, Berlin, Deutschland

    Volker Schulz

  2. Am Sellsiekbach 52, 32657, Lemgo, Deutschland

    Norbert Rietbrock

  3. Institut für Klinische Pharmakologie, Universitätsklinikum Charité der Humboldt-Universität zu Berlin Campus Mitte, Schumannstraβe 20/21, 10117, Berlin, Deutschland

    Ivar Roots

  4. Am Allersberg 7, 65191, Wiesbaden, Deutschland

    Dieter Loew

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Johne, A. et al. (2002). Übersicht zu Interaktionsstudien mit Johanniskrautextrakten. In: Schulz, V., Rietbrock, N., Roots, I., Loew, D. (eds) Phytopharmaka VII. Steinkopff, Heidelberg. https://doi.org/10.1007/978-3-642-57528-0_15

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