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Haare pp 499–570Cite as

Allgemeine Therapie von Haarkrankheiten

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Zusammenfassung

Haarwuchsprobleme sind häufig, Betroffene zeigen einen oft hohen Leidensdruck, und die Behandlungsmöglichkeiten sind beschränkt. Vor diesem Hintergrund hat die Bewältigung von Haarproblemen auf den Ebenen des Informationsverhaltens, der Problemlösekompetenz und der medizinischen Therapie zu erfolgen.

Die Erfahrung ist die Probe des Rationalen — und so umgekehrt.

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Literatur

  • Fey MF, Bührer A (2001) Klinische Fachliteratur kritisch lesen. Teil I: Fussangeln in Fallberichten und Fallserien. Schweiz Med Forum 7:161–165

    Google Scholar 

  • Fey MF, Bührer A (2001) Klinische Fachliteratur kritisch lesen. Teil II: Randomisierte Studien, Meta-Analysen und Publikationsprobleme. Schweiz Med Forum 7:166–171

    Google Scholar 

  • Grilli R, Freemantle N, Minozzi S et al. (1999) Einfluss von Massenmedien auf die Inanspruchnahme medizinischer Leistungen. Schweiz Rundsch Med Prax 88:1839

    Google Scholar 

  • Lange S (2000) Statistische Signifikanz und klinische Relevanz. Zeitschr Hautkrankh 4:225–229

    Google Scholar 

  • Trüeb RM, Schweizerische Arbeitsgruppe für Trichologie (2000) Die Wechselbeziehung zwischen Arzt, Friseur und Medien im Management von Haarverlust. Hautarzt 51:729–732

    Article  PubMed  Google Scholar 

  • Trüeb RM, de Viragh P, Schweizerische Arbeitsgruppe für Trichologie (2001) Stellenwert der Kopfhaare und Therapie von Haarausfall bei Männern in der Schweiz. Schweiz Rundsch Med Prax 90:241–248

    Google Scholar 

  • Trüeb RM, Itin P, Schweizerische Arbeitsgruppe für Trichologie (2001) Fotografische Dokumentation der Wirksamkeit von 1 mg oralem Finasterid in der Behandlung der androgenetischen Alopezie des Mannes im Praxisalltag in der Schweiz. Schweiz Rundsch Med Prax 90:2087–2093

    Google Scholar 

■ Literatur

  • Ackerman AB, Kligman AM (1969) Some observations on dandruff. J Soc Cosm Chem 20:81–101

    Google Scholar 

  • Adams RM, Maibach HI (1985) A five-year study of cosmetic reactions. J Am Acad Dermatol 13:1062–1069

    Article  PubMed  CAS  Google Scholar 

  • Bouillon C (1996) Shampoos. Clin Dermatol 14:113–121

    Article  PubMed  CAS  Google Scholar 

  • Christophers E (1995) Mehr Nutzen als Risiken durch Teershampoos. Polyzyklische aromatische Kohlenwasserstoffe in der Diskussion. Forsch Prax 201: 28–30

    Google Scholar 

  • Dawber R (1996) Hair: Its structure and response to cosmetic preparations. Clin Dermatol 14:105–112

    Article  PubMed  CAS  Google Scholar 

  • Dawber R (1996) Shampoos — scientific basis and clinical aspects. International Congress and Symposium Series 216. The Royal Society of Medicine Press Limited, London

    Google Scholar 

  • Domsch A, Pospischil H, Schuster G, Tronnier H (1996) Kosmetisch-dermatologische Wirkungen von Eiweisshydrolysaten. Parfüm Kosmet 61:325–330

    Google Scholar 

  • Fewings J, Menné T (1999) An update of the risk assessment for methylchloroisothiazolinone/methylisothiazolinone (MCI/MI) with focus on rinse-off products. Contact Dermatitis 41:1–13

    Article  PubMed  CAS  Google Scholar 

  • Fransway AF (1991) The problem of preservation in the 1990s: I. Statement of the problem, solution(s) of the industry, and the current use of formaldehyde and formaldehyde-releasing biocides. Am J Contact Derm 2:6–23

    Google Scholar 

  • Futterer E (1988) Antidandruff hair tonic containing piroctone olamine. Cosmet Toiletries 103:49–52

    CAS  Google Scholar 

  • Kullavanijaya P, Gritiyarangsan P, Bisalbutra P et al. (1992) Absence of effects of dimethicone-and non-dimethicone-containing shampoos on daily hair loss rates. J Soc Cosm Chem 43:195–206

    CAS  Google Scholar 

  • Merk HF, Mukhtar H, Kaufmann I et al. (1987) Human hair follicle benzo[a]pyrene and benzo[a]pyrene 7,8-diol metabolisme: effect of exposure to a coal tar containing shampoo. J Invest Dermatol 88:71–76

    Article  PubMed  CAS  Google Scholar 

  • Merk H, Loew D, Lorke D (1990) Topische Anwendung des Steinkohlenteers: Nutzen-Risiko-Abwägung aus klinischer, pharmakologischer und toxikologischer Sicht. Akt Dermatol 16:147–151

    Google Scholar 

  • Pittelkow MR, Perry HO, Muller SA et al. (1980) Skin cancer in patients with psoriasis treated with coal tar. Arch Dermatol 117:465–468

    Article  Google Scholar 

  • Price NCP (1995) 50 years of surfactants cosmetic cleansing and emulsions. Cosmet Toiletries 110:49–66

    Google Scholar 

  • Reng AK (1977) Rezeptierung von Haarreinigungsund-nachbehandlungspräparaten mit speziellen Eigenschaften.SÖFW 8/9/11:1–9

    Google Scholar 

  • Rushton H, Gummer CL, Flasch H (1994) 2-in-1 shampoo technology: state of the art shampoo and conditioner in one. Skin Pharmacol 7:78–83

    Article  PubMed  CAS  Google Scholar 

  • Shapiro J, Maddin S (1996) Medicated shampoos. Clin Dermatol 14:123–128

    Article  PubMed  CAS  Google Scholar 

  • Spoor HJ (1973) Shampoos. Cutis 12:167–168

    Google Scholar 

  • Spoor HJ (1977) Shampoos and hair dyes. Cutis 20: 189–190

    PubMed  CAS  Google Scholar 

  • Sugimura T, Sato S, Nagao M et al. (1976) Overlapping of carcinogens and mutagens. In: Magee, Takayana, Sugimura, Matsushima (eds) Fundamentals in Cancer Prevention. University of Tokyo Press, Tokyo, p 191

    Google Scholar 

  • Swisher RD (1987) Surfactant Biodegradation. Marcel Dekker, New York

    Google Scholar 

  • Trüeb RM (1998) Haarwaschmittel (Shampoos): Zusammensetzung und klinische Anwendungen. Hautarzt 49:895–901

    Article  PubMed  Google Scholar 

  • Urbano CC (1995) 50 years of hair care development. Cosmet Toiletries 110:85–104

    Google Scholar 

  • Van Schooten FJ, Moonen EJ, Rhynsburger E et al. (1994) Dermal uptake of polycyclic aromatic hydrocarbons after hair wash with coal tar shampoo. Lancet 344:1505–1506

    Article  PubMed  Google Scholar 

  • Zviak C, Bouillon C (1986) Hair treatment and hair care products. In: Zviak C (ed) The Science of Hair Care. Marcel Dekker, New York, pp 87–147

    Google Scholar 

  • Zviak C, Vanlerberghe G (1986) Scalp and hair hygiene. In: Zviak C (ed) The Science of Hair Care. Marcel Dekker, New York, pp 49–86

    Google Scholar 

■ Literatur

  • Brenner S, Matz H (1999) Improvement in androgenetic alopecia in 53-76-year-old men using oral finasteride. Int J Dermatol 38:926–930

    Article  Google Scholar 

  • Castro-Maganoa M, Angulo M, Fuentes B et al. (1996) Effect of finasteride on human testicular steroidgenesis. J Androl 17:516–521

    Google Scholar 

  • Chen W, Zouboulis ChC, Orfanos CE (1996) The 5-alpha reductase system and its inhibitors. Recent developments and its perspectives in treating androgen-dependent skin disorders. Dermatol 193:177–184

    Article  CAS  Google Scholar 

  • Dallob AL, Sadick NS, Unger W et al. (1994) The effect of finasteride, a 5 alpha-reductase inhibitor, on scalp skin testosterone and dihydrotestosterone concentrations in patients with male pattern baldness. J Clin Endocrinol Metab 79:703–706

    Article  PubMed  CAS  Google Scholar 

  • Gormley GJ, Stoner E, Bruskewitz RC et al. (1992) The effect of finasteride in men with benign prostatic hyperplasia. N Engl J Med 327:1185–1191

    Article  PubMed  CAS  Google Scholar 

  • Gormley GJ (1995) Finasteride: a clinical review. Biomed Pharmacother 49:319–324

    Article  PubMed  CAS  Google Scholar 

  • Harris GS, Kozarich JW (1997) Steroid 5alpha-reductase inhibitors in androgen-dependent disorders. Curr Opin Chem Biol 1:254–259

    Article  PubMed  CAS  Google Scholar 

  • Kaufman KD (1996) Clinical studies on the effects of oral finasteride, a type II 5α-reductase inhibitor, on scalp hair in men with male pattern baldness. In: van Neste D, Randall VA (eds) Hair Research for the Next Millenium. Elsevier, Amsterdam, pp 363–365

    Google Scholar 

  • Kaufman KD, Olsen EA, Whiting D et al. (1998) Finasteride in the treatment of men with androgenetic alopecia (male pattern hair loss). J Am Acad Dermatol 36:578–589

    Article  Google Scholar 

  • Leyden J, Dunlap F, Miller B et al. (1999) Finasteride in the treatment of men with frontal male pattern hair loss. J Am Acad Dermatol 40:930–937

    Article  PubMed  CAS  Google Scholar 

  • Mazzarella F, Loconsole F, Cammisa A et al. (1997) Topical finasteride in the treatment of androgenic alopecia. J Dermatol Treatment 8:189–192

    Article  Google Scholar 

  • Navarro Guerrero J, Lorduy Oses L. Galenic-pharmaceutical study of pieces of Proscar® (finasteride 5 mg) tablets and finasteride 1 mg capsules versus Propecia® in the treatment of androgenetic alopecia (im Druck)

    Google Scholar 

  • Overstreet JW, Fuh VL, Gould J et al. (1999) Chronic treatment with finasteride daily does not affect spermatogenesis or semen production in young men. J Urol 162:1295–1300

    Article  PubMed  CAS  Google Scholar 

  • Price VH, Roberts JL, Hordinsky M et al. (2000) Lack of efficacy of finasteride in postmenopausal women with androgenetic alopecia. J Am Acad Dermatol 43:768–776

    Article  PubMed  CAS  Google Scholar 

  • Rittmaster RS (1994) Finasteride. N Engl J Med 330: 120–125

    Article  PubMed  CAS  Google Scholar 

  • Sudduth SL, Koronkowski MJ (1993) Finasteride: the first 5 alpa-reductase inhibitor. Pharmacotherapy 13:309–325

    PubMed  CAS  Google Scholar 

  • Trüeb RM, Itin P und Schweizerische Arbeitsgruppe für Trichologie (2002) Fotografische Dokumentation der Wirksamkeit von 1 mg oralem Finasterid in der Behandlung der androgenetischen Alopezie des Mannes im Praxisalltag. Schweiz Rundsch Med Prax 90:2087–2093

    Google Scholar 

  • Van Neste D, Fuh V, Sanchez-Pedreno P et al. (2000) Finasteride increases anagen hair in men with androgenetic alopecia. Br J Dermatol 143:804–810

    Article  PubMed  Google Scholar 

  • Wolff H, Kunte C (1998) Die Behandlung der androgenetischen Alopezie des Mannes mittels systemischer 5-Reduktase-Hemmung. Hautarzt 49:813–817

    Article  PubMed  CAS  Google Scholar 

■ Literatur

  • Moltz L, Schwartz U, Hammerstein J (1980) Die klinische Anwendung von Antiandrogenen bei der Frau. Gynäkologe 13:1–17

    PubMed  CAS  Google Scholar 

  • Sawaya ME, Hordinsky MK (1993) The antiandrogens. When and how they should be used. Dermatol Clin 11:65–72

    PubMed  CAS  Google Scholar 

■ Literatur

  • Buhl AE, Waldon DJ, Kawabe TT, Holland JM (1989) Minoxidil stimulates mouse vibrissae follicles in organ culture. J Invest Dermatol 92:315–320

    Article  PubMed  CAS  Google Scholar 

  • Buhl AE (1991) Minoxidil’s action in hair follicles. J Invest Dermatol 96(Suppl):73S–74S

    Article  PubMed  CAS  Google Scholar 

  • Civatte J, Laux B, Simpson NB, Vickers CFH (1987) 2% topical minoxidil solution in male pattern baldness: preliminary European results. Dermatologica 175(Suppl):42–49

    Article  PubMed  Google Scholar 

  • De Groot AC, Nater JP, Herxheimer A (1987) Minoxidil: hope for the bald? Lancet 1:1019–1022

    Article  PubMed  Google Scholar 

  • De Villez RL (1990) The therapeutic use of topical minoxidil. Dermatol Clin 8:367–375

    Google Scholar 

  • De Villez RL, Jacobs JP, Szpunar CA, Varner ML (1994) Androgenetic alopecia in the female. Treatment with 2% topical minoxidil solution. Arch Dermatol 3:303–307

    Google Scholar 

  • Ebner H, Müller E (1995) Allergic contact dermatitis from minoxidil. Contact Dermatitis 32:316–317

    Article  PubMed  CAS  Google Scholar 

  • Headington JT, Novak E (1984) Clinical and histologic studies of male pattern baldness treated with topical minoxidil. Curr Ther Res 36:1098–1106

    Google Scholar 

  • Katz HI, Hien NT, Prawer SE, Goldman SJ (1987) Long-term efficacy of topical minoxidil in male pattern baldness. J Am Acad Dermatol 16:711–718

    Article  PubMed  CAS  Google Scholar 

  • Katz HI (1988) Topical minoxidil: review of efficacy. Clin Dermatol 6:195–199

    Article  PubMed  CAS  Google Scholar 

  • Katz HI (1989) Topical minoxidil: review of efficacy and safety. Cutis 43:94–98

    PubMed  CAS  Google Scholar 

  • Kreindler TG (1987) Topical minoxidil in early androgenetic alopecia. J Am Acad Dermatol 16:718–724

    Article  PubMed  CAS  Google Scholar 

  • Kubilus J, Kvedar JC, Baden HP (1987) Effect of minoxidil on pre-and postconfluent keratinocytes. J Am Acad Dermatol 16:648–652

    Article  PubMed  CAS  Google Scholar 

  • Olsen EA (1989) Treatment of androgenetic alopecia with topical minoxidil. Res Staff Phys 35:53–69

    Google Scholar 

  • Olsen EA, Weiner MS, Amara IA, DeLong ER (1990) Five-year follow-up of men with androgenetic alopecia treated with topical minoxidil. J Am Acad Dermatol 22:643–646

    Article  PubMed  CAS  Google Scholar 

  • Price VH, Menefee E (1990) Quantitative estimation of hair growth. I. Androgenetic alopecia in women: effect of minoxidil. J Invest Dermatol 95:683–687

    Article  PubMed  CAS  Google Scholar 

  • Price VH, Menefee E, Strauss PC (1999) Changes in hair weight and hair count in men with androgenetic alopecia, after application of 5% and 2% topical minoxidil, placebo, or no treatment. J Am Acad Dermatol 41:717–721

    Article  PubMed  CAS  Google Scholar 

  • Rietschel RL, Duncan SH (1987) Safety and efficacy of topical minoxidil in the management of androgenetic alopecia. J Am Acad Dermatol 16:677–685

    Article  PubMed  CAS  Google Scholar 

  • Savin RC, Atton AV (1993) Minoxidil. Update on its clinical role. Dermatol Clin 11:55–64

    PubMed  CAS  Google Scholar 

  • Scheman AJ, West DP, Hordinsky MK et al. (2000) Alternative formulation for patients with contact reactions to topical 2% and 5% minoxidil vehicle ingredients. Contact Dermatitis 42:241

    PubMed  CAS  Google Scholar 

  • Tosti A, Bardazzi F, De Padova MO et al. (1985) Contact dermatitis to minoxidil. Contact Dermatitis 13:275–276

    Article  PubMed  CAS  Google Scholar 

  • Van der Willligen AH, Dutree-Meulenberg ROGM, Stolz E et al. (1987) Topical minoxidil sensitization in androgenic alopecia. Contact Dermatitis 17:44–45

    Article  Google Scholar 

  • Whiting DA, Jacobson C (1992) Treatment of female androgenetic alopecia with minoxidil 2%. Int J Dermatol 31:800–804

    Article  PubMed  CAS  Google Scholar 

  • Whitmore EX (1992) The importance of proper vehicle selection in the detection of minoxidil sensitivity. Arch Dermatol 128:653–656

    Article  PubMed  CAS  Google Scholar 

  • Wilson C, Walkden V, Powell S et al. (1991) Contact dermatitis in reaction to 2% topical minoxidil solution. J Am Acad Dermatol 24:661–662

    Article  PubMed  CAS  Google Scholar 

  • Zins GR (1988) The history of the development of minoxidil. Clin Dermatol 6:132–147

    Article  PubMed  CAS  Google Scholar 

■ Literatur

  • Enders HJ (1980) Zur Therapie von Haarausfall unterschiedlichster Genese mit einem östrogen-und kortikoidhaltigen Externum. Z Hautkr 55:14–18

    Google Scholar 

  • Gottswinter J (1984) Gynäkomastie durch östrogenhaltiges Haarwasser. Med Klein 79:181–183

    Google Scholar 

  • Hevert F (2000) 17α-Estradiol — ein moderner Inhibitor der 5α-Reductase. In: Plettenberg A, Meigel WN, Mill I (Hrsg) Dermatologie an der Schwelle zum neuen Jahrtausend. Springer, Berlin Heidelberg, S 435–437

    Chapter  Google Scholar 

  • Kiesewetter F, Schell H (2002) Wirksamkeit von 17α-Estradiol in der Therapie der Alopecia androgenetica (im Druck)

    Google Scholar 

  • Orfanos CE, Vogels L (1980) Lokaltherapie der Alopecia androgenetica mit 17-alpha-Östradiol. Dermatologica 161:124–132

    Article  PubMed  CAS  Google Scholar 

  • Schumacher-Stock U, Winkler K (1977) Die externe Östrogentherapie der androgenetischen Alopezie. Hautarzt 11(Suppl):336–338

    Google Scholar 

  • Wozel G (2002) Lokaltherapie der androgenetischen Alopezie mit 17α-Estradiol bei Frauen und Männern (im Druck)

    Google Scholar 

  • Wüstner H, Orfanos CE (1974) Alopecia androgenetica und ihre Lokalbehandlung mit östrogen-und corticosteroidhaltigen Externa. Z Hautkr 49:879–888

    PubMed  Google Scholar 

■ Literatur

  • Berth-Jones J, Burney AMC, Hutchinson PE (1994) Diphencyprone is not detectable in serum or urine following topical application. Acta Dermatol Venereol (Stockh) 74:312–313

    CAS  Google Scholar 

  • Cotellessa C, Peris K, Caracciolo E et al. (2001) The use of topical diphenylcyclopropenone for the treatment of extensive alopecia areata. J Am Acad Dermatol 44:73–76

    Article  PubMed  CAS  Google Scholar 

  • Gianetti A, Orecchia G (1983) Clinical experience on the treatment of alopecia areata with squaric acid dibutylester. Dermatologica 167:280–282

    Article  Google Scholar 

  • Gordon P, Aldridge G, McVittie E et al. (1996) Topical diphencyprone for alopecia areata: evaluation of 48 cases after 30 months’ follow-up. Br J Dermatol 134:869–871

    Article  PubMed  CAS  Google Scholar 

  • Happle R, Kalveran K, Buchner U et al. (1980) Contact allergy as therapeutic tool for alopecia areata: application of squaric acid dibutylester. Dermatologica 161:289–297

    Article  PubMed  CAS  Google Scholar 

  • Hatzis J, Gourgiotou K, Tosca A (1988) Vitiligo as a reaction to topical treatment with diphencyprone. Dermatologica 177:146–148

    Article  PubMed  CAS  Google Scholar 

  • Hoffmann R, Happle R (1996) Topical immunotherapy in alopecia areata: What, how, and why? Dermatol Clin 14:739–744

    Article  PubMed  CAS  Google Scholar 

  • Micali G, Licastro-Cicero R, Nasca MR (1996) Treatment of alopecia areata with squaric acid dibutylester. Int J Dermatol 35:52–56

    Article  PubMed  CAS  Google Scholar 

  • Monk B (1989) Induction of hair growth in alopecia totalis with diphencyprone sensitization. Clin Exp Dermatol 14:154–157

    Article  PubMed  CAS  Google Scholar 

  • Orrechia G, Rabbiosi G (1990) Treatment of alopecia areata with diphencyprone. Dermatologica 171: 193–196

    Article  Google Scholar 

  • Pericin M, Trüeb RM (1998) Topical immunotherapy of severe alopecia areata with diphenylcyclopropenone: evaluation of 68 cases. Dermatology 196: 418–421

    Article  PubMed  CAS  Google Scholar 

  • Perret CM, Steijlen PM, Zaun H, Happle R (1990) Erythema multiforme-like eruptions: a rare side effect of topical immunotherapy with diphenylcyclopropenonen. Dermatologica 180:5–7

    Article  PubMed  CAS  Google Scholar 

  • Rokhsar CK, Shupack JL, Vafai JJ et al. (1990) Efficacy of topical sensitizers in the treatment of alopecia areata. J Am Acad Dermatol 39:751–761

    Article  Google Scholar 

  • Shapiro J (1993) Topical immunotherapy in the treatment of chronic severe alopecia areata. Dermatol Clin 11:611–617

    PubMed  CAS  Google Scholar 

  • Tosti A, Guerra L, Bardazzi F (1989) Contact urticaria during topical immunotherapy. Contact Dermatitis 21:196–197

    Article  PubMed  CAS  Google Scholar 

  • Tosti A, Guidetti MS, Bardazzi F et al. (1996) Long-term results of topical immunotherapy in children with alopecia totalis or alopecia universalis. J Am Acad Dermatol 35:199–201

    Article  PubMed  CAS  Google Scholar 

  • Van der Steen P, van Baar H, Perret C (1991) Treatment of alopecia areata with diphenylcyclopropenone. J Am Acad Dermatol 24:227–230

    Article  PubMed  Google Scholar 

  • Van der Steen PHM, van Baar HMJ, Happle R et al. (1991) Prognostic factors in the treatment of alopecia areata with diphenylcyclopropenone. J Am Acad Dermatol 24:227–230

    Article  PubMed  Google Scholar 

  • Van der Steen P, Boezeman J, Happle R (1992) Topical immunotherapy for alopecia areata: re-evaluation of 139 cases after additional follow-up period of 19 months. Dermatology 184:198–201

    Article  PubMed  Google Scholar 

  • Van der Steen P, Happle R (1992) ‘Dyschromia in confetti’ as a side effect of topical immunotherapy with diphenylcyclopropenone. Arch Dermatol 128: 518–520

    Article  PubMed  Google Scholar 

  • Weise K, Kretzschmar L, John SM et al. (1996) Topical immunotherapy in alopecia areata: anamnestic and clinical criteria of prognostic significance. Dermatology 192:129–133

    Article  PubMed  CAS  Google Scholar 

  • Wilkerson MG, Henkin J, Wilkin JK (1984) Diphenylcyclopropenone: examination for potential contaminants, mechanisms of sensitization, and photochemical stability. J Am Acad Dermatol 11:802–807

    Article  PubMed  CAS  Google Scholar 

  • Wilkerson MG, Henkin J, Wilkin JK (1985) Squaric acid and esters: analysis for contaminants and stability in solvents. J Am Acad Dermatol 13:229–234

    Article  PubMed  CAS  Google Scholar 

■ Literatur

  • Cornell RC, Stoughton RB (1987) Review of super-potent topical corticosteroids. Semin Dermatol 6:72–76

    Google Scholar 

  • DuVivier A, Stoughton RB (1975) Tachyphylaxis to the action of topically applied steroids. Arch Dermatol 111:581–583

    Article  PubMed  Google Scholar 

  • Firooz A, Tehranchi-Nia Z, Ahmed AR (1995) Benefits and risks of intralesional corticosteroid injection in the treatment of dermatological diseases. Clin Exp Dermatol 20:363–370

    Article  PubMed  CAS  Google Scholar 

  • Goldermann R, Teilkemeier P, Lehmann P et al. (1992) Typ-IV-Sensibilisierung gegen Kortikoide. Z Hautkr 67:430–435

    Google Scholar 

  • Lagos BR, Maibach HI (1998) Frequency of application of topical corticosteroids: an overview. Brit J Dermatol 139:763

    Article  CAS  Google Scholar 

  • Lester RS, Knowles SR, Shear NH (1998) The risks of systemic corticosteroid use. Dermatol Clin 16:277–288

    PubMed  CAS  Google Scholar 

  • Mori M, Pimpinelli N, Giannotti B (1994) Topical corticosteroids and unwanted local effects. Improving the benefit/risk ratio. Drug Saf 10:406–412

    Article  PubMed  CAS  Google Scholar 

  • Pflugshaupt C (1983) Diskontinuierliche topische Corticoidtherapie. Z Hautkr 148:1229–1238

    Google Scholar 

  • Reinhold U, Buttgereit F (2000) Hochdosis-Steroid-Pulstherapie. Gibt es Indikationen in der Dermatologie? Hautarzt 51:738–745

    Article  PubMed  CAS  Google Scholar 

  • Smith EW (1995) Four decades of topical corticosteroid assessment. Curr Probi Dermatol 22:124–131

    CAS  Google Scholar 

  • Smith JG, Wahr RF, Chalker DK (1976) Corticosteroid induced atrophy and telangiectasia. Arch Dermatol 112:1115–1117

    Article  PubMed  Google Scholar 

  • Staughton RCD, August PJ (1975) Cushing’s syndrome and pituitary-adrenal suppression due to clobetasol propionate. Br Med J 2:419–421

    Article  PubMed  CAS  Google Scholar 

  • White KP, Driscoll MS, Rothe MJ, Grant-Kels JM (1994) Severe adverse cardiovascular effects of pulse steroid therapy: is continuous monitoring necessary? J Am Acad Dermatol 30:768–773

    Article  PubMed  CAS  Google Scholar 

  • Wolverton SE (1992) Monitoring for adverse effects from systemic drugs used in dermatology. J Am Acad Dermatol 26:661–679

    Article  PubMed  CAS  Google Scholar 

■ Literatur

  • Anstey A (1995) Azathioprine in dermatology: a review in the light of advances in understanding methylation pharmacogenetics. J R Soc Med 88:155–160

    Google Scholar 

  • Tan BB, Lear JT, Gawkrodger DJ et al. (1997) Azathioprine in dermatology: a survey of current practice in the U.K. Br J Dermatol 136:351–355

    Article  PubMed  CAS  Google Scholar 

  • Younger IR, Harris DW, Colver GB (1991) Azathioprine in dermatology. J Am Acad Dermatol 25: 281–286

    Article  PubMed  CAS  Google Scholar 

  • Wolverton SE (1992) Monitoring for adverse effects from systemic drugs used in dermatology. J Am Acad Dermatol 26:661–679

    Article  PubMed  CAS  Google Scholar 

■ Literatur

■ Literatur

  • Ho VC, Gupta AK, Ellis CH et al. (1990) Treatment of severe lichen planus with cyclosporine. J Am Acad Dermatol 22:64–68

    Article  PubMed  CAS  Google Scholar 

  • Kahan BD (1989) Cyclosporine. N Engl J Med 321:1725–1738

    Article  PubMed  CAS  Google Scholar 

  • Palestine AG, Nussenblatt RB, Chan C-C (1984) Side effects of systemic cyclosporine in patients not undergoing transplantation. Am J Med 77:652–658

    Article  PubMed  CAS  Google Scholar 

  • Peter RU, Ruzicka T (1992) Cyclosporin A in der Therapie entzündlicher Dermatosen. Hautarzt 43:687–694

    PubMed  CAS  Google Scholar 

  • Ruzicka T (1995) Cyclosporin in less common immune-mediated skin diseases. Br J Dermatol 48: 40–42

    Google Scholar 

  • Sönnichsen N (1993) Die Wirksamkeit von Ciclosporin bei Sonderformen der Psoriasis und nichtpsoriatischen Dermatosen. Dermatol Monatsschr 179: 163–168

    Google Scholar 

  • Wolverton SE (1992) Monitoring for adverse effects from systemic drugs used in dermatology. J Am Acad Dermatol 26:661–679

    Article  PubMed  CAS  Google Scholar 

■ Literatur

  • Ochsendorf FR, Runne U (1991) Chloroquin und Hydroxychloroquin: Nebenwirkungsprofil wichtiger Therapeutika. Hautarzt 42:140–146

    PubMed  CAS  Google Scholar 

  • Wolverton SE (1992) Monitoring for adverse effects from systemic drugs used in dermatology. J Am Acad Dermatol 26:661–679

    Article  PubMed  CAS  Google Scholar 

■ Literatur

  • Wolverton SE (1992) Monitoring for adverse effects from systemic drugs used in dermatology. J Am Acad Dermatol 26:661–679

    Article  PubMed  CAS  Google Scholar 

  • Wozel G (1996) Dapson. Pharmakologie, Wirkmechanismus und klinischer Einsatz. Georg Thieme, Stuttgart

    Google Scholar 

■ Literatur

  • Dicken CH (1984) Retinoids: a review. J Am Acad Dermatol 11:541–552

    Article  PubMed  CAS  Google Scholar 

  • Lesnik RH, Mezick JA, Capetola R, Kligman LH (1989) Topical all-trans-retinoic acid prevents corticosteroid-induced skin atrophy without abrogating the anti-inflammatory effect. J Am Acad Dermatol 21:186–190

    Article  PubMed  CAS  Google Scholar 

  • McMichael AJ, Griffiths CE, Talwar HS et al. (1996) Concurrent application of tretinoin (retinoic acid) partially protects against corticosteroid-induced epidermal atrophy. Br J Dermatol 135:60–64

    Article  PubMed  CAS  Google Scholar 

  • Orfanos CE (1989) Retinoide: der neue Stand. Erhaltungstherapie, Resorptionsstörungen bei “non-responders”, Interaktionen und Interferenzen mit Medikamenten, Behandlung von Kindern und Knochentoxizität, Acitretin und 13-cis-Acitretin. Hautarzt 40:123–129

    PubMed  CAS  Google Scholar 

  • Saurat J-H (1998) Systemic retinoids. What’s new? Dermatol Clin 16:331–340

    Article  PubMed  CAS  Google Scholar 

  • Wolverton SE (1992) Monitoring for adverse effects from systemic drugs used in dermatology. J Am Acad Dermatol 26:661–679

    Article  PubMed  CAS  Google Scholar 

■ Literatur

  • Barnes L, Altmeyer P, Forstrom L, Stentstrom MH (2000) Long-term treatment of psoriasis with calcipotriol scalp solution and cream. Eur J Dermatol 10:199–204

    PubMed  CAS  Google Scholar 

  • Czarnetzki BM (1989) Vitamin D3 in Dermatology: a critical appraisal. Dermatologica 178:184–188

    Article  PubMed  CAS  Google Scholar 

  • Duweb GA, Abuzariba O, Rahim M et al. (2000) Scalp psoriasis: topical calcipotriol 50 microgram/g/ml solution vs. Betamethasone 17-valerate 1% solution. Int J Clin Pharmacol Res 20:65–68

    PubMed  CAS  Google Scholar 

  • Green C, Gampule M, Harris D et al. (1994) Comparative effects of calcipotriol (MC903) solution and placebo (vehicle MC903) in the treatment of psoriasis of the scalp. Br J Dermatol 130:483–487

    Article  PubMed  CAS  Google Scholar 

  • Klaber MR, Hutchinson PE, Pedvis-Leftick A et al. (1994) Comparative effects of calcipotriol solution (50 micrograms/ml) and betamethasone 17-valerate solution (1 mg/ml) in the treatment of scalp psoriasis. Br J Dermatol 131:678–683

    Article  PubMed  CAS  Google Scholar 

  • Van de Kerkhof PCM, van Bokhoven M, Zultak M et al. (1989) A double-blind study of topical 1α,25-di-hydroxyvitamin D3 in psoriasis. Br J Dermatol 120:661–664

    Article  PubMed  Google Scholar 

■ Literatur

  • Reimann S, Luger T, Metze D (2000) Topische Anwendung von Capsaicin in der Dermatologie zur Therapie von Juckreiz und Schmerz. Hautarzt 51:164–172

    Article  PubMed  CAS  Google Scholar 

■ Literatur

  • Abdel-Rahman SM, Nahata MC, Powell DA (1997) Response to initial griseofulvin therapy in pediatric patients with tinea capitis. Ann Pharmacother 31:406–410

    PubMed  CAS  Google Scholar 

  • Abdel-Rahman SM, Nahata MC (1997) Oral terbinafine: a new antifungal agent. Ann Pharmacother 31:445–456

    PubMed  CAS  Google Scholar 

  • Abdel-Rahman SM, Powell DA, Nahata MC (1998) Efficacy of itraconazole in children with Trichophyton tonsurans tinea capitis. J Am Acad Dermatol 38:443–446

    Article  PubMed  CAS  Google Scholar 

  • Albengres E, le Louet H, Tillement JP (1998) Systemic antifungal agents. Drug interactions of clinical significance. Drug Saf 18:83–97

    Article  PubMed  CAS  Google Scholar 

  • Amichai B, Grunwald MH (1998) Adverse drug reactions of the new oral antifungals — terbinafine, fluconazole and itraconazole. Int J Dermatol 37:410–415

    Article  PubMed  CAS  Google Scholar 

  • Bennett ML, Fleischer AB, Loveless JW, Feldman SR (2000) Oral griseofulvin remains the treatment of choice for tinea capitis in children. Pediat Dermatol17:304–309

    Article  CAS  Google Scholar 

  • De Beule K, van Gestel J (2001) Pharmacology of itraconazole. Drugs 61(Suppl):27–37

    Article  PubMed  Google Scholar 

  • Dragos V, Lunder M (1997) Lack of efficacy of 6-week treatment with oral terbinafine for tinea capitis due to Microsporum canis in children. Pediat Dermatol 14:46–48

    Article  CAS  Google Scholar 

  • Elewski BE (1999) Treatment of tinea capitis: beyond griseofulvin. J Am Acad Dermatol 40:27–30

    Article  Google Scholar 

  • Friedlander SF (1999) The evolving role of itraconazole, fluconazole and terbinafine in the treatment of tinea capitis. Pediat Infect Dis J 18:205–210

    Article  CAS  Google Scholar 

  • Goldman L (1970) Griseofulvin. Med Clin North Am 54:1339–1345

    PubMed  CAS  Google Scholar 

  • Gupta AK, Sauder DN, Shear NH (1994) Antifungal agents: an overview. Part I. J Am Acad Dermatol 30:677–698

    Article  PubMed  CAS  Google Scholar 

  • Gupta AK, Sauder DN, Shear NH (1994) Antifungal agents: an overview. Part II. J Am Acad Dermatol 30:911–933

    Article  PubMed  CAS  Google Scholar 

  • Gupta AK, Shear NH (1997) Terbinafine: an update. J Am Acad Dermatol 37:979–988

    Article  PubMed  CAS  Google Scholar 

  • Gupta AK, Alexis ME, Raboobee N et al. (1997) Itraconazole pulse therapy is effective in the treatment of tinea capitis in children: an open multicentre study. Br J Dermatol 137:251–254

    Article  PubMed  CAS  Google Scholar 

  • Gupta AK, Adam P, de Doncker P (1998) Itraconazole pulse therapy for tinea capitis: a novel treatment schedule. Pediat Dermatol 15:225–228

    Article  CAS  Google Scholar 

  • Gupta AK, Adam P (1998) Terbinafine pulse therapy is effective in tinea capitis. Pediat Dermatol 15:56–58

    Article  CAS  Google Scholar 

  • Gupta AK, Adam P, Soloman R, Aly R (1999) Itraconazole oral solution for the treatment of tinea capitis using the pulse regimen. Cutis 64:192–194

    PubMed  CAS  Google Scholar 

  • Gupta AK, Katz HI, Shear NH (1999) Drug interactions with itraconazole, fluconazole, and terbinafine and their management. J Am Acad Dermatol 41:237–249

    Article  PubMed  CAS  Google Scholar 

  • Gupta AK, Dlova N, Taborda P et al. (2000) Once weekly fluconazole is effective in the treatment of tinea capitis: a prospective, multicentre study. Br J Dermatol 142:965–968

    Article  PubMed  CAS  Google Scholar 

  • Haroon TS, Hussain I, Aman S et al. (1996) A randomized double-blind comparative study of terbinafine for 1, 2 and 4 weeks in tinea capitis. Br J Dermatol 135:86–88

    Article  PubMed  CAS  Google Scholar 

  • Hoffman HL, Ernst EJ, Klepser ME (2000) Novel triazole antifungal agents. Expert Opin Invest Drugs 9:593–605

    Article  CAS  Google Scholar 

  • Jones TC (1995) Overview of the use of terbinafine (Lamisil®) in children. Br J Dermatol 132:683–689

    Article  PubMed  CAS  Google Scholar 

  • Katz HI (1999) Drug interactions of the newer oral antifungal agents. Br J Dermatol 141(Suppl):26–32

    Article  PubMed  Google Scholar 

  • Knasmuller S, Parzefall W, Helma C et al. (1997) Toxic effects of griseofulvin: disease models. Mechanisms, and risk assessment. Crit Rev Toxicol 27: 495–537

    Article  PubMed  CAS  Google Scholar 

  • Korting HC, Schaller M (2001) Neue Entwicklungen in der medizinischen Mykologie. Hautarzt 52:91–97

    Article  PubMed  CAS  Google Scholar 

  • Leyden J (1998) Pharmacokinetics and pharmacology of terbinafine and itraconazole. J Am Acad Dermatol 38:42–47

    Article  Google Scholar 

  • Lopez-Gomez S, del Palacia A, van Custem J et al. (1994) Itraconazole versus griseofulvin in the treatment of tinea capitis: a double blind randomized study in children. Int J Dermatol 33:743–747

    Article  PubMed  CAS  Google Scholar 

  • Moossavi M, Bagheri B, Scher RK (2001) Systemic antifungal therapy. Dermatol Clin 19:35–52

    Article  PubMed  CAS  Google Scholar 

  • Montero GF (1998) Fluconazole in the treatment of tinea capitis. Int J Dermatol 37:870–871

    Article  Google Scholar 

  • Nejjam F, Zagula M, Carbiac MD et al. (1995) Pilot study of terbinafine in children suffering from tinea capitis: evalution of efficacy, safety, and pharmacokinetics. Br J Dermatol 132:98–105

    Article  PubMed  CAS  Google Scholar 

  • Pierard GE, Arrese JE, Pierard-Franchimont C (2000) Itraconazole. Expert Opin Pharmacother 1:287–304

    Article  PubMed  CAS  Google Scholar 

  • Rand S (2000) Overview. The treatment of dermatophytosis. J Am Acad Dermatol 43(Suppl):S104–S112

    Article  PubMed  CAS  Google Scholar 

  • Smith EB (2000) The treatment of dermatophytosis: safety considerations. J Am Acad Dermatol 43(Suppl5):S113–S119

    Article  PubMed  CAS  Google Scholar 

  • Solomon BA, Collins R, Sharma R et al. (1997) Fluconazole for the treatment of tinea capitis in children. J Am Acad Dermatol 37:274–275

    Article  PubMed  CAS  Google Scholar 

  • Stevens DA (1999) Itraconazole in cyclodectrin solution. Pharmacotherapy 19:603–611

    Article  PubMed  CAS  Google Scholar 

  • Suarez S, Friedlander SF (1998) Antifungal therapy in children: an update. Pediat Ann 27:177–184

    CAS  Google Scholar 

■ Literatur

  • Abeck D, Korting HC (1991) Einsatz von Antibiotika bei Hauterkrankungen. Bayer Internist 2:45–53

    Google Scholar 

  • Feingold DS, Wagner RF (1989) Antibacterial therapy. J Am Acad Dermatol 14:535–548

    Article  Google Scholar 

■ Literatur

  • Arndt KA (1988) Adverse reactions to acyclovir: topical, oral and intravenous. J Am Acad Dermatol 18:188–190

    Article  PubMed  CAS  Google Scholar 

  • Evans TY, Tyring SK (1998) Advances in antiviral therapy in dermatology. Dermatol Clin 16:409–420

    PubMed  CAS  Google Scholar 

■ Literatur

  • Eggensperger H (1980) Wirkstoffe zur Hautdesinfektion. Dtsch Apoth Ztg 120:28–30

    Google Scholar 

  • Kwochka K, Kowalski J (1991) Prophylactic efficacy of four antibacterial shampoos against Staphylococcus intermedius in dogs. Am J Vet Res 52:115–118

    PubMed  CAS  Google Scholar 

  • Michael J (1977) Klinische Erfahrungen mit Betaisadona-Mikrobiziden in Chirurgie und Orthopädie. Therapiewoche 27:9328–9330

    Google Scholar 

  • Sebben JE (1983) Surgical antiseptics. J Am Acad Dermatol 9:759–765

    Article  PubMed  CAS  Google Scholar 

  • Torricelli R, Wüthrich B (1996) Life-threatening anaphylactic shock due to skin application of chlorhexidine. Clin Exp Dermatol 26:112

    CAS  Google Scholar 

■ Literatur

  • Bowerman J, Gomez M, Austin R, Wold D (1987) Comparative study of permethrin 1% creme rinse and lindane shampoo for the treatment of head lice. Pediat Infect Dis J 6:252–255

    Article  CAS  Google Scholar 

  • Burkhart CG, Burkhart CN, Burkhart KM (1998) An assessment of topical and oral prescription and over-the-counter treatments for head lice. J Am Acad Dermatol 36:979–982

    Article  Google Scholar 

  • Carson D (1988) Pyrethrins combined with pipetonyl butoxide (RID) vs 1% permethrin (NIX) in the treatment of head lice. Am J Dis Child 142:768–769

    PubMed  CAS  Google Scholar 

  • Haustein UF (1991) Pyrethrine und Pyrethroide (Permethrin) bei der Behandlung von Skabies und Pediculosis. Hautarzt 42:9–15

    PubMed  CAS  Google Scholar 

  • Taplin D, Castillero PM, Spiegel J et al. (1982) Malathion for treatment of Pediculus humanus var capitis infestation. JAMA 247:3103–3105

    Article  PubMed  CAS  Google Scholar 

  • Taplin D, Meinking T, Castillero P, Sanchez R (1986) Permethrin 1% creme rinse for the treatment of Pediculus humanus var capitis infestation. Pediat Dermatol 3:344–348

    Article  CAS  Google Scholar 

■ Literatur

  • Ash K, Lord J, Newman J et al. (1999) Hair removal using a long-pulsed alexandrite laser. Dermatol Clin 17:387–399

    Article  PubMed  CAS  Google Scholar 

  • Bencini PL, Luci A, Galimberti M et al. (1999) Long-term epilation with long-pulsed neodymium: YAG laser. Dermatol Surg 25:175–178

    Article  PubMed  CAS  Google Scholar 

  • Bjerring P, Zacharia H, Lybecker H et al. (1998) Evaluation of the free-running ruby laser for hair removal — a retrospective study. Acta Dermatol Venereol (Stockh) 78:48–51

    Article  CAS  Google Scholar 

  • Boss WK Jr, Usal H, Thompson RC et al. (1999) A comparison of the long-pulse and short-pulse alexandrite laser hair removal systems. Ann Plast Surg 42:381–384

    Article  PubMed  Google Scholar 

  • Campos VB, Dierickx CC, Farinelli WA et al. (2000) Hair removal with an 800-nm pulsed diode laser. J Am Acad Dermatol 43:442–447

    Article  PubMed  CAS  Google Scholar 

  • Connolly CS, Paolini L (1997) Study reveals successful removal of unwanted hair with LPIR laser. Cosmet Dermatol 10:38–40

    Google Scholar 

  • Dierickx CC, Grossman MC, Farinelli WA et al. (1997) Long-pulsed ruby laser hair removal. Lasers Surg Med 9(Suppl):167

    Google Scholar 

  • Dierickx CC, Grossman MC, Farinelli WA et al. (1998) Hair removal by a pulsed, infrared laser system. Lasers Surg Med 10(Suppl):198

    Google Scholar 

  • Dierickx CC, Grossman MC, Farinelli WA et al. (1998) Permanent hair removal by normal mode ruby laser. Arch Dermatol 134:837–842

    Article  PubMed  CAS  Google Scholar 

  • Dierickx CC, Grossman MC, Farinelli WA et al. (1998) Comparison between a long-pulsed ruby laser and pulsed, infrared laser system for hair removal. Lasers Surg Med 10(Suppl):199

    Google Scholar 

  • Dierickx CC, Alora MB, Dover JS (1999) A clinical overview of hair removal using lasers and light sources. Dermatol Clin 17:357–366

    PubMed  CAS  Google Scholar 

  • Duque V, Dierickx C, Lin D et al. (1998) Long-pulsed ruby laser for hair removal: comparisons between different spot size, temperatures, and interval between first and second treatment. Lasers Surg Med 10(Suppl):39

    Google Scholar 

  • Finkel B, Eliezri YD, Waldman A et al. (1997) Pulsed alexandrite laser technology for noninvasive hair removal. J Clin Laser Med Surg 15:225–229

    PubMed  CAS  Google Scholar 

  • Garcia C, Alamoudi H, Nakib M et al. (2000) Alexandrite laser hair removal is safe for Fitzpatrick skin types IV-VI. Dermatol Surg 26:130–134

    Article  PubMed  CAS  Google Scholar 

  • Gold MH, Bell MW, Foster TD et al. (1997) Long-term epilation using the Epilight broad band, intense pulsed light hair removal system. Dermatol Surg 23:909–913

    Article  PubMed  CAS  Google Scholar 

  • Goldberg DJ, Littler CM, Wheeland RG (1997) Topical suspension-assisted Q-switched Nd:YAG laser hair removal. Dermatol Surg 23:741–745

    Article  PubMed  CAS  Google Scholar 

  • Goldberg DJ, Samady JA (2000) Evaluation of a long-pulse Q-switched Nd:YAG laser for hair removal. Dermatol Surg 26:109–113

    Article  PubMed  CAS  Google Scholar 

  • Görcü M, Asian G, Aköz T et al. (2000) Comparison of alexandrite laser and electrolysis for hair removal. Dermatol Surg 26:37–41

    Article  Google Scholar 

  • Grossman MC, Dierickx C, Farinelli W et al. (1996) Damage to hair follicles by normal-mode ruby laser irradiation. J Am Acad Dermatol 35:889–894

    Article  PubMed  CAS  Google Scholar 

  • Gudat W, Hassoun G (1992) Epilation. Deutsche Dermatol 3:354–357

    Google Scholar 

  • Hobbs ER, Ratz JL, James B (1985) Electrosurgical epilation. Dermatol Clin 5:437–444

    Google Scholar 

  • Lask G, Elman M, Slatkine M et al. (1997) Laser-assisted hair removal by selective photothermolysis. Preliminary results. Dermatol Surg 23:737–739

    Article  PubMed  CAS  Google Scholar 

  • Littler CM (1999) Hair removal using a Nd:Yag laser system. Dermatol Clin 17:401–430

    Article  PubMed  CAS  Google Scholar 

  • Lynfield YL, Mac Williams P (1970) Shaving and hair growth. J Invest Dermatol 55:170–172

    Article  PubMed  CAS  Google Scholar 

  • McDaniel DH, Lord J, Ash K et al. (1999) Laser hair removal. A review and report on the use of the long-pulsed alexandrite laser for hair reduction of the upper lip, leg, back, and bikini region. Dermatol Surg 25:425–430

    Article  PubMed  CAS  Google Scholar 

  • Nanni CA, Alster TS (1997) Optimizing treatment parameters for hair removal using a topical carbon-based solution and 1064-nm Q-switched neodymium: YAG laser energy. Arch Dermatol 133: 1546–1549

    Article  PubMed  CAS  Google Scholar 

  • Olsen EA (1999) Methods of hair removal. J Am Acad Dermatol 40:143–155

    Article  PubMed  CAS  Google Scholar 

  • Richards RN, Meharg G (1995) Electrolysis: observation from 13 years and 140000 hours of experience. J Am Acad Dermatol 33:662–666

    Article  PubMed  CAS  Google Scholar 

  • Ross EV, Ladin Z, Kreindel M et al. (1999) Theoretical considerations in laser hair removal. Dermatol Clin 17:333–355

    PubMed  CAS  Google Scholar 

  • Schroeter CA, Raulin C, Thürlimann W et al. (1999) Hair removal in 40 hirsute women with an intense laser-like light source. Eur J Dermatol 9:374–379

    PubMed  CAS  Google Scholar 

  • Scott MJ, Scott MJ III, Scott HM (1990) Epilation. Cutis 46:216–217

    PubMed  Google Scholar 

  • Smith SR, Tse Y, Adit SK et al. (1998) Long-term results of hair photo-epilation. Lasers Surg Med (Suppl) 10:43

    Google Scholar 

  • Solomon MP (1998) Hair removal using the long-pulsed ruby laser. Ann Plast Surg 41:1–6

    Article  PubMed  CAS  Google Scholar 

  • Tse Y (1999) Hair removal using a pulsed-intense light source. Dermatol Clin 17:373–385

    Article  PubMed  CAS  Google Scholar 

  • Wagner RF (1990) Physical methods for the management of hirsutism. Cutis 45:19–26

    Google Scholar 

  • Williams R, Havoonjian H, Isagholian K et al. (1998) A clinical study of hair removal using the long-pulsed ruby laser. Dermatol Surg 24:837–842

    Article  PubMed  CAS  Google Scholar 

  • Williams RM, Christian MM, Moy RL (1999) Hair removal using the long-pulsed ruby laser. Dermatol Clin17:367–372

    Article  PubMed  CAS  Google Scholar 

■ Literatur

  • Board JA, Rosenberg SM, Smeltzer JS (1987) Spironolactone and estrogen-progestin therapy for hirsutism. South Med J 80:483–486

    Article  PubMed  CAS  Google Scholar 

  • Camacho FM (1999) SAHA syndrome: female androgenetic alopecia and hirsutism. Exp Dermatol 8:304–305

    PubMed  CAS  Google Scholar 

  • Carmina E, Lobo RA (1998) The addition of dexamethasone to antiandrogen therapy for hirsutism prolongs the duration of remission. Fertil Steril 69:1075–1079

    Article  PubMed  CAS  Google Scholar 

  • Castello R, Tosi F, Perrone F et al. (1996) Outcome of long-term treatment with the 5-alpha-reductase inhibitor finasteride in idiopathic hirsutism: clinical and hormonal effects during a 1-year course of therapy and 1-year follow-up. Fertil Steril 66:734–740

    PubMed  CAS  Google Scholar 

  • Chapman MG, Sowsett M, Dewhurst CJ et al. (1984) Spironolactone in combination with an oral contraceptive: an alternative treatment for hirsutism. Br J Obstet Gynecol 92:983–985

    Google Scholar 

  • Cusan L, Dupont A, Belanger A et al. (1990) Treatment of hirsutism with the pure antiandrogen flutamide. J Am Acad Dermatol 23:462–469

    Article  PubMed  CAS  Google Scholar 

  • Erenus M, Yücelten D, Durmusoglu F, Gürbüz O (1997) Comparison of finasteride versus spironolactone in the treatment of idiopathic hirsutism. Fertil Steril 68:1000–1003

    Article  PubMed  CAS  Google Scholar 

  • Givens JR, Andersen RN, Wiser WL et al. (1975) The effectiveness of two oral contraceptives in suppressing plasma androstendione, testosterone, LH and FSH and in stimulating plasma testosterone binding capacity in hirsute women. Am J Obstet Gynecol 124:333–339

    Google Scholar 

  • Hammerstein J, Cupceancu B (1969) Behandlung des Hirsutismus mit Cyproteronacetat. Dtsch Med Wschr 94:829–834

    Article  PubMed  CAS  Google Scholar 

  • Hammerstein J, Meckies J, Leo-Rossberg I et al. (1975) Use of cyproterone acetate (CPA) in the treatment of acne, hirsutism and virilism. J Steroid Biochem 6:827–836

    Article  PubMed  CAS  Google Scholar 

  • Hauner H, Ditschuneit HH, Bals SB et al. (1988) Fat distribution, endocrine and metabolic profile in obese women with and without hirsutism. Metabolism 37:281–285

    Article  PubMed  CAS  Google Scholar 

  • Kelestimur F, Sahin Y (1998) Comparison of Diane 35 and Diane 35 plus spironolactone in the treatment of hirsutism. Fertil Steril 69:66–69

    Article  PubMed  CAS  Google Scholar 

  • Labhart A (1990) 3000 Jahre Therapie des Hirsutismus. Zu W. Daums „Die Königin von Saba“. Schweiz Med Wochenschr 120:83–84

    PubMed  CAS  Google Scholar 

  • Lobo RA (1986) “Idiopathic hirsutism” — fact or fiction. Sem Reprod Endocrinol 4:179–184

    Article  Google Scholar 

  • Lubowe I (1971) Achard-Thiers syndrome. Arch Dermatol 103:544–545

    Article  PubMed  CAS  Google Scholar 

  • Moghetti P, Castello R, Negri C et al. (1995) Flutamide in the treatment of hirsutism: long-term clinical effects, endocrine changes, and androgen receptor blockade. Fertil Steril 64:511–517

    PubMed  CAS  Google Scholar 

  • Muderris II, Bayram F, Sahin Y et al. (1996) The efficacy of 250 mg/day flutamide in the treatment of patients with hirsutism. Fertil Steril 66:220–222

    PubMed  CAS  Google Scholar 

  • Muller SA (1973) Hirsutism: a review of the genetic and experimental aspects. J Invest Dermatol 60: 457–471

    Article  PubMed  CAS  Google Scholar 

  • Pawlikowski M, Komorowski J (1983) Hyperostosis frontalis, galactorrhoea/hyperprolactinaemia, and Morgagni-Stewart-Morel syndrome. Lancet I:474

    Article  Google Scholar 

  • Tolino A, Petrone A, Sarnacchiario F et al. (1996) Finasteride in the treatment of hirsutism: new therapeutic perspectives. Fertil Steril 66:61–65

    PubMed  CAS  Google Scholar 

  • Venturoli S, Marescalchis O, Colombo FM et al. (1999) A prospective randomized trial comparing low dose flutamide, finasteride, ketoconazole and cyproterone acetate-estrogen regimens in the treatment of hirsutism. J Clin Endocrinol Metab 84: 1304–1310

    Article  PubMed  CAS  Google Scholar 

  • Vexiau P, Bourdou P, Fiet J et al. (1995) 17β-estradiol: oral or parenteral administration in hyperandrogenic women? Metabolic tolerance in association with cyproterone acetate. Fertil Steril 63:508–515

    PubMed  CAS  Google Scholar 

  • Wang IL, Morris RS, Chang L et al. (1995) A prospective randomized trial comparing finasteride to spironolactone in the treatment of hirsute women. J Clin Endocrinol Metab 80:233–238

    Article  Google Scholar 

  • Watson RE, Bouknight R, Alguire PC (1995) Hirsutism: evaluation and management. J Gen Intern Med 10:283–292

    Article  PubMed  CAS  Google Scholar 

■ Literatur

  • Malhorta B, Palmisano M, Schrode K et al. (2000) Percutaneous absorption, pharmacokinetics and dermal safety of eflornithine 15% cream in hirsute women (Poster). American Academy of Dermatology 58th Annual Meeting, San Francisco, März 10-15, 2000

    Google Scholar 

  • Schrode K, Huber F, Stszak J et al. (2000) Randomized, double-blind, vehicle-controlled safety and efficacy evaluation of eflornithine 15% cream in the treatment of women with excessive facial hair (Poster). American Academy of Dermatology 58th Annual Meeting, San Francisco, März 10-15, 2000

    Google Scholar 

■ Literatur

  • Ahmad W, Faiyaz ul Haque M, Brancolini V et al. (1998) Alopecia universalis associated with a mutation in the human hairless gene. Science 279:720–724

    Article  PubMed  CAS  Google Scholar 

  • Cotsarellis G, Sun TT, Lavker RM (1990) Label-retaining cells reside in the bulge area of pilosebaceous unit: implications for follicular stem cells, hair cycle and skin carcinogenesis. Cell 61:1329–1337

    Article  Google Scholar 

  • Grossman MC, Wimberly J, Dwyer P et al. (1995) PDT for hirsutism. Lasers Surg Med 7(Suppl):44

    Google Scholar 

  • Grossman MC (1997) What is new in cutaneous laser research. Dermatol Clin 15:1–8

    PubMed  CAS  Google Scholar 

  • Li L, Hoffman RM (1995) The feasibility of targeted selective gene therapy of the hair follicle. Nature Med 1:705–706

    Article  PubMed  Google Scholar 

  • Protopapa EE, Gaissert H, Xenckis A et al. (1999) The effect of proteolytic enzymes on hair follicles of transgenic mice expressing the lac Z-protein in cells of the bulge region. J Eur Acad Dermatol 13:28–35

    Article  CAS  Google Scholar 

■ Literatur

  • Casagrande F, Lehner H, Lienhard B, Simmen A (1998) Haare — Cheveux — Capelli. Handbuch für den Coiffeurberuf. Schweizerische Coiffeurfachlehrer-Vereinigung

    Google Scholar 

  • Dauer H-G (2000) Haarwebesystem (“hair weaving”). In: Plettenberg A, Meigel WN, Moll I (Hrsg) Dermatologie an der Schwelle zum neuen Jahrtausend. Aktueller Stand von Klinik und Forschung. Springer, Berlin, S 725–730

    Google Scholar 

  • Farm G (1998) Contact allergy to colophony. Clinical and experimental studies with emphasis on clinical relevance. Acta Dermatol Venereol Suppl (Stockh) 201:1–42

    CAS  Google Scholar 

  • Rayner VL (1994) Camouflage cosmetics. In: Baran R, Maibach HI (eds) Cosmetic Dermatology. Williams & Wilkins, Baltimore, pp 205–226

    Google Scholar 

  • Unger WP (1977) Alternatives in hair replacement. Cutis 19:623–628

    PubMed  CAS  Google Scholar 

  • Van der Velden EM, Drost BH, Ijsselmuiden OE et al. (1998) Dermatography as a new treatment for alopecia areata of the eyebrows. Int J Dermatol 37: 617–621

    Article  PubMed  Google Scholar 

■ Literatur

  • Friederich HC, Georg ML (1990) Operative Behandlung der Alopezie. Akt Dermatol 16:7–16

    Google Scholar 

  • Hanke CW, Bergfeld WF (1979) Fiber implantation for pattern baldness. JAMA 241:146–148

    Article  PubMed  CAS  Google Scholar 

  • Hanke CW, Norins AL, Pantzer JG, Bennett J (1981) Hair implant complications. JAMA 245:1344–1345

    Article  PubMed  CAS  Google Scholar 

  • Lepaw MI (1979) Complications of implantation of synthetic fibers into scalp for “hair” replacement. J Dermatol Surg Oncol 5:201–204

    PubMed  CAS  Google Scholar 

  • Limmer Bl (1995) Elliptical donor stereoscopically assisted micrografting as an approach to further refinement in hair transplantation. J Dermatol Surg Oncol 20:789–793

    Google Scholar 

  • Lukas M, Halsner U (1990) Haartransplantationen bei Frauen — neue Perspektiven der Mini-Graft-Technik. Akt Dermatol 16:17–20

    Google Scholar 

  • Marritt M, Konior RJ (1994) Patient selection, candidacy, and treatment plan for hair replacement surgery. Facial Plastic Surg Clin North Am 2:111–131

    Google Scholar 

  • Mühlbaur W (1970) Haartransplantationen bei post-traumatischer Alopezie. Münch med Wschr 37: 1655–1659

    Google Scholar 

  • Nelson BR, Stough DB, Stough DB, Johnson T (1991) Hair transplantation in advanced male pattern alopecia. The role of incicional slit grafting. J Dermatol Surg Oncol 17:567–573

    PubMed  CAS  Google Scholar 

  • Norwood OT (1984) Transplanting temporal points, sideburns and feminine hairline. J Dermatol Surg Oncol 10:958–961

    PubMed  CAS  Google Scholar 

  • Norwood OT (1992) Patient selection, hair transplant design, and hairstyle. J Dermatol Surg Oncol 18: 386–394

    PubMed  CAS  Google Scholar 

  • Peluso AM, Fanti PA, Monti M et al. (1992) Cutaneous complications of artificial hair implantation: a pathological study. Dermatology 184:129–132

    Article  PubMed  CAS  Google Scholar 

  • Rassman WR, Carson S (1995) Micrografting in extensive quantities. Dermatol Surg 21:306–311

    Article  PubMed  CAS  Google Scholar 

  • Stough DB, Miner JE (1997) Male pattern alopecia. Surgical options. Dermatol Clin 15:609–622

    Article  PubMed  CAS  Google Scholar 

  • Stough DW, Potter TS (1997) Philosophy and technique in hair restoration surgery. Curr Probi Dermatol 9:113–136

    Article  Google Scholar 

  • Swinehart JM, Griffin EI (1991) Slit grafting: the use of serrated island grafts in male and female-pattern alopecia. J Dermatol Surg Oncol 17:243–253

    PubMed  CAS  Google Scholar 

  • Uebel CO (1991) Micrografts and minigrafts: a new approach for baldness surgery. Ann Plast Surg 27:476–487

    Article  PubMed  CAS  Google Scholar 

  • Unger MG (1992) Scalp reduction. Clin Dermatol 10:345–355

    Article  PubMed  CAS  Google Scholar 

  • Unger WP, David LM (1994) Laser hair transplantation. J Dermatol Surg Oncol 20:515–521

    PubMed  CAS  Google Scholar 

  • Unger WP (1996) What’s new in hair replacement surgery? Dermatol Clin 14:783–802

    Article  PubMed  CAS  Google Scholar 

■ Literatur

  • Bleuler E (1975) Das autistisch-undisziplinierte Denken in der Medizin und seine Überwindung. Springer, Berlin

    Google Scholar 

  • Klobusch J, Mössier K, Rabe T, Runnebaum B (1990) Neue Ansätze in Diagnostik und Therapie der Alopezie in der Gynäkologie. Ther Umsch 47:985–990

    PubMed  CAS  Google Scholar 

  • Lange S (1999) Statistisch signifikant — auch relevant für den Patienten? Med Klin 94(Suppl):22–24

    Article  Google Scholar 

  • Lassus A, Eskelinen E (1992) A comparative study of a new food supplement, ViviScal, with fish extract for the treatment of hereditary androgenetic alopecia in young males. J Int Med Res 20:445–453

    PubMed  CAS  Google Scholar 

  • Loussouarn G, Courtois M, Horuseau C et al. (1997) A new approach to the prevention and cosmetic treatment of alopecia. Aminexil. BEDC 5:1–5

    Google Scholar 

  • Maddin WS, Bell PW, James JHM (1990) The biological effects of a pulsed electrostatic field with specific reference to hair. Int J Dermatol 29:446–450

    Article  PubMed  CAS  Google Scholar 

  • Maddin S (1992) Electrotrichogenesis: further evidence of efficacy and safety on extended use. Int J Dermatol 31:878–880

    Article  PubMed  CAS  Google Scholar 

  • Mössier K (1991) Thymu-Skin: Neuer Therapieansatz bei der Behandlung der Alopecia androgenetica und der Alopecia areata. Deutsch Dermatol 39: 3–10

    Google Scholar 

  • Sawaya ME, Shapiro J (2000) Alopecia: unapproved treatments or indications. Clin Dermatol 18:177–186

    Article  PubMed  CAS  Google Scholar 

■ Literatur

  • Ahmad W, Faiyaz ul Haque M, Brancolini V et al. (1998) Alopecia universalis associated with a mutation in the human hairless gene. Science 279:720–724

    Article  PubMed  CAS  Google Scholar 

  • Augustin M (2001) Erfassung von Lebensqualität in dermatologischen Studien. Leitlinie der Subkommission „Pharmako-Ökonomie und Lebensqualität“. Hautarzt 52:697–700

    CAS  Google Scholar 

  • Badiavas EV, Falanga V (2001) Gene therapy. J Dermatol 28:175–192

    PubMed  CAS  Google Scholar 

  • Braun-Falco M, Hallek M (1998) Hautgentherapie — Perspektiven des Gentransfers in Keratinozyten. Hautarzt 49:536–544

    Article  PubMed  CAS  Google Scholar 

  • Chan EF, Gat U, McNiff JM, Fuchs E (1999) A common human skin tumour is caused by activating mutations in beta-catenin. Nat Gene 21:410–413

    Article  CAS  Google Scholar 

  • Cotsarelis G, Sun TT, Lavker RM (1990) Label-retaining cells reside in the bulge area of pilosebaceous unit: implications for follicular stem cells, hair cycle and skin carcinogenesis. Cell 61:1329–1337

    Article  PubMed  CAS  Google Scholar 

  • Davis ST, Benson BG, Bramson HN et al. (2001) Prevention of chemotherapy-induced alopecia in rats by CDK inhibitors. Science 291:134–137

    Article  PubMed  CAS  Google Scholar 

  • De Luca M, Pellegrini G (1997) The importance of epidermal stem cells in keratinocyte-mediated gene therapy. Gene Ther 4:381–383

    Article  PubMed  CAS  Google Scholar 

  • Finlay AY, Khan GK (1994) Dermatology life quality index (DLQI) — a simple practical measure for routine clinical use. Clin Expe Dermatol 19:210–216

    Article  CAS  Google Scholar 

  • Fischer TW, Schmidt S, Strauss B, Eisner P (2001) Hairdex. Ein Instrument zur Untersuchung der krankheitsbezogenen Lebensqualität bei Patienten mit Haarerkrankungen. Hautarzt 52:219–227

    Article  PubMed  CAS  Google Scholar 

  • Fuchs E (1998-99) Beauty is skin deep: the fascinating biology of the epidermis and its appendages. Harvey Lect 94:47–77

    PubMed  Google Scholar 

  • Fuchs E, Merrill BJ, Jamora C, DasGupta R (2001) At the roots of a never-ending cycle. Dev Cell 1:13–25

    Article  PubMed  CAS  Google Scholar 

  • Gat U, DasGupta R, Degenstein L, Fuchs E (1998) De Novo hair follicle morphogenesis and hair tumors in mice expressing a truncated beta-catenin in skin. Cell 95:605–614

    Article  PubMed  CAS  Google Scholar 

  • Hoffman RM (1998) Topical liposome targeting of dyes, melanins, genes, and proteins selectively to hair follicles. J Drug Target 5:67–74

    Article  PubMed  CAS  Google Scholar 

  • Hoffmann R (2001) TrichoScan: combining epiluminiscence microscopy with digital image analysis for the measurement of hair growth in vivo. Eur J Dermatol 11:362–368

    PubMed  CAS  Google Scholar 

  • Jahoda CAB, Oliver RF, Reynolds AJ et al. (2001) Transspecies hair growth induction by human hair follicle dermal papillae. Exp Dermatol 10:229–237

    Article  PubMed  CAS  Google Scholar 

  • Li L, Hoffman RM (1995) The feasibility of targeted selective gene therapy of the hair follicle. Nature Med 1:705–706

    Article  PubMed  Google Scholar 

  • Lu B, Federoff HJ, Wang Y et al. (1997) Topical application of viral vectors for epidermal gene transfer. J Invest Dermatol 108:803–808

    Article  PubMed  CAS  Google Scholar 

  • McKay IA, Winyard P, Leigh IM, Bustin SA (1994) Nuclear transcription factors: potential targets for new modes of intervention in skin disease. Br J Dermatol 131:591–597

    Article  PubMed  CAS  Google Scholar 

  • Millar SE (2002) Molecular mechanisms regulating hair follicle development. J Invest Dermatol 118:216–225

    Article  PubMed  CAS  Google Scholar 

  • Paus R, Menrad A, Czarnetski B (1995) Nekrobiologie der Haut: Apoptose. Hautarzt 46:285–303

    PubMed  CAS  Google Scholar 

  • Paus R, Christoph T, Müller-Röver S (1999) Immunology of the hair follicle: a short journey into terra incognita. Invest Dermatol Symp Proc 4:226–234

    Article  CAS  Google Scholar 

  • Paus R, Müller-Röver S, Botchkarev VA (1999) Chrono-biology of the hair follicle: hunting the “hair cycle clock”. Invest Dermatol Symp Proc 4:338–345

    Article  CAS  Google Scholar 

  • Reynolds AJ, Lawrence C, Cserhalmi-Friedman PB, Christiano AM, Jahoda CA (1999) Trans-gender induction of hair follicles. Human follicle cells can be induced to grow in an incompatible host of the other sex. Nature 402:33–34

    Article  PubMed  CAS  Google Scholar 

  • Ritzmann P (2000) Medizinische Informationen auf dem Internet. Schweiz Rundsch Med Prax 89:706–710

    Google Scholar 

  • Shum D, Martinka M, Bernardo O et al. (2001) Computer-assisted histomorphometric evaluation of scalp biopsies (abstract 257). J Invest Dermatol 117:432

    Google Scholar 

  • Trüeb RM (1998) Von der Hippokratischen Glatze zum “Gen-Shampoo”: Fortschritte der Trichologie im Jahrtausendwechsel. Akt Dermatol 24:101–107

    Google Scholar 

  • Trüeb RM (1998) Mutation des menschlichen hairless-Gens bei Atrichia universalis. Hautarzt 49:678–689

    Article  Google Scholar 

  • Trüeb RM (2000) Kampf der Glatze: Von der Magie zur Therapie. Neue Zürcher Zeitung 102:73

    Google Scholar 

  • Trüeb RM, Swiss Trichology Study Group (2001) The value of hair cosmetics and pharmaceuticals. Dermatology 202:275–282

    Article  PubMed  Google Scholar 

  • Trüeb RM (2001) Das Haar im Spiegel der Geschichte. In: Burg G, Geiges ML (Hrsg) Die Haut, in der wir leben. Zu Markt getragen und zur Schau gestellt. Rüffer & Rub, Zürich, S 160–166

    Google Scholar 

  • van Genderen C, Okamura RM, Farinas I et al. (1994) Development of several organs that require inductive epithelial-mesenchymal interactions is impaired in LEF-1-deficient mice. Genes Dev 15: 2691–2703

    Article  Google Scholar 

  • Wagner RW (1994) Gene inhibition using antisense oligonucleotides. Nature 372:333–335

    Article  PubMed  CAS  Google Scholar 

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Trüeb, R.M. (2003). Allgemeine Therapie von Haarkrankheiten. In: Haare. Steinkopff, Heidelberg. https://doi.org/10.1007/978-3-642-57448-1_6

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