Zusammenfassung
Jede postmenopausale Hormonsubstitution bedarf einer Indikation und deren gelegentlicher Überprüfung. Die regelmäßige klinische Überwachung ermöglicht die Wirkungen der Therapie zu überprüfen, Nebenwirkungen zu erkennen und Modifikationen der Behandlung vorzunehmen. Da heute auch im menschlichen Organismus nicht sezernierte östrogene sowie synthetische Gestagene in der Hormonsubstitution eingesetzt werden, wäre wohl die Bezeichnung Hormontherapie korrekter.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
Literatur
Allgemeines/Übersichten/key studies/Symptomatik
Braendle W (2000) Das Klimakterium. Wissenschaftliche Verlagsgesellschaft Stuttgart. ISBN 3-8047-1712-8
Dören M (1998) Hormonsubstitution in Klimakterium und Postmenopause — Vorschläge zur individualisierten Therapie. Thieme Verlag, Stuttgart New York, 2. Auflage. ISBN 3-13-107 362-4
Stellungnahme der Deutschen Menopause Gesellschaft e. V. Hormonsubstitution in Klimakterium und Postmenopause. www.menopause-gesellschaft.de
MacLennan A et al (2001) Oral replacement therapy versus placebo for hot flushes. (Cochrane Review) Cochrane Database Syst Rev (1); CD 002978
Norman RJ et al (2000) Oestrogen and progestogen hormone replacement therapy for peri-menopausal and post-menopausal women: weight and body fat distribution. (Cochrane Review) Cochrane Database Syst Rev (2); CD 001018
Espeland MA et al (1995) Rationale, design, and conduct of the PEPI trial. Postmenopausal Estrogen/progestin Interventions. Control Clin Trials 16:3S–19S
The Women’s Health Initiative Study Group (1998) Design of the Women’s Health Initiative Clinical trial and observational Study. Control Clin Trials 19:61–109
Barrett-Connor E, Stuenkel C (2001) Hormone replacement therapy (HRT) — risks and benefits. Int J Epidemiol 30:423–426
Manson JE, Martin KA (2001) Postmenopausal hormone replacement therapy. New Engl J Med 345:34–40
Hlatky MA et al (2002) Quality-of-life and depressive symptoms in postmenopausal women after receiving hormone therapy. JAMA 287:591–597
Modelska K, Cummings St (2002) Tibolone for postmenopausal women: systematic review of randomized trials. J Clin Endocrinol Metab 87:16–23
Osteoporose
O’Connell D et al (1998) A systematic review of the skeletal effects of estrogen therapy in postmenopausal women. II. An assessment of treatment effects. Climacteric 1:112–123
Komulainen M et al (1998) HRT and vit D in prevention of non-vertebral fractures in postmenopausal women; a 5-year randomized trial. Maturitas 31:5–54
Mosekilde L et al (2000) Hormonal replacement therapy reduces forearm fracture incidence in recent postmenopausal women — results of the Danish Osteoporosis Prevention Study. Maturitas 36:181–193
Dören M, Samsioe G (2000) Prevention of Postmenopausal Osteoporosis with Estrogen Replacement Therapy and associated Compounds — Update on clinical trials since 1995-Human Reprod Update 6:419–426
Torgerson DJ, Bell-Syer SEM (2001) Hormone replacement therapy and prevention of nonvertebral fractures. JAMA 285:2891–2897 und Ergänzung der Meta-Analyse in JAMA 286:2097
Nevitt MC et al (2001) The effect of estrogen plus progestin on knee symptoms and related disability in postmenopausal women: The Heart and Estrogen/Progestin Replacement Study, a randomized, double-blind,placebo-controlled trial. Arthritis Rheum 44:811–818
Musgrove DS et al (2001) Back problems among postmenopausal women taking estrogen replacement therapy: the study of osteoporotic fractures. Spine 26:1606–1612
Cauley JA et al (2001) Effects of hormone replacement on clinical fractures and height loss: The Heart and Estrogen/Progestin Replacement Study (HERS). Am J Med 110:442–450
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2002 Springer-Verlag Berlin Heidelberg
About this chapter
Cite this chapter
Dören, M. (2002). Substitution mit Sexualhormonen in der Postmenopause. In: Hedtmann, A., Götte, S. (eds) Osteoporose. Praktische Orthopädie, vol 41. Steinkopff, Heidelberg. https://doi.org/10.1007/978-3-642-57442-9_8
Download citation
DOI: https://doi.org/10.1007/978-3-642-57442-9_8
Publisher Name: Steinkopff, Heidelberg
Print ISBN: 978-3-7985-1300-6
Online ISBN: 978-3-642-57442-9
eBook Packages: Springer Book Archive