Skip to main content
SpringerLink
Log in

Prophylaxe und Therapie einer Osteoporose mit Vitamin D und Calcium

  • Chapter
Osteoporose

Part of the book series: Praktische Orthopädie ((PRAKORTHO,volume 41))

  • 113 Accesses

Zusammenfassung

Die ausreichende Versorgung mit Calcium und Vitamin D3 hat für die Prophylaxe und Therapie der Osteoporose einen Stellenwert, der oft unterschätzt wird. Im Folgenden wird auf die Bedeutung von Calcium und Vitamin D3 für die Knochenmasse, die Wirkungsmechanismen und die Möglichkeiten der Gewährleistung einer ausreichenden Versorgung eingegangen.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 44.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 59.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

Literatur

  • Baron JA, Beach M, Mandel JS, van Stolk RU, Haue RW, Sandler RS, Rothstein R, Summers RW, Snover DC, Beck GJ, Bond JH, Greenberg ER, for the Calcium Polyp Prevention Study Group (1999) Calcium supplements for the prevention of colorectal adenomas. N Engl J Med 340:101–107

    Article  PubMed  CAS  Google Scholar 

  • Black DM, Cummings SR, Karpf DB, Cauley JA, Thompson DE, Nevitt MC, Bauer DC, Genant HK, Haskell WL, Marcus R, Ott SM, Torner JC, Quandt SA, Reiss TF, Ensrud KE, for the Fracture Intervention Trial Research Group (1996) Randomized trial of effect of alendronate on risk of fracture in women with existing vertebral fractures. Lancet 348:1535–1541

    Article  PubMed  CAS  Google Scholar 

  • Bonjour JP, Slosman D, Barclay D, Rizzoli R (1999) A significant effect of calcium-enriched foods on bone mineral mass gain is maintained more than 3 years after discontinuation of intervention. J Bone Miner Res 1 (14) (Suppl):S185

    Google Scholar 

  • Bostick RM, Kushi LH, Wu Y, Meyer KA, Sellers TA, Folsom AR (1999) Relation of calcium, vitamin D, and dairy food intake to ischemic heart disease mortality among postmenopausal women. Am J Epidemiol 149:151–161

    Article  PubMed  CAS  Google Scholar 

  • Cadogan J, Blumsehn A, Barker M, Eastell R (1998) A longitudinal study of bone gain in pubertal girls: anthropometric and biochemical correlates. J Bone Miner Res 13:1602–1612

    Article  PubMed  CAS  Google Scholar 

  • Chapuy MC, Arlot ME, Duboeuf F, Brun J, Crouzet B, Arnaud S, Delmas PD, Meunier PJ (1992) Vitamin D3 and calcium to prevent hip fractures in elderly women. N Engl J Med 327:1637–1642

    Article  PubMed  CAS  Google Scholar 

  • Chevalley T, Rizzoli R, Nydegger V, Slossman D, Rapin CH, Michel JP, Vasey H, Bonjour JP (1994) Effects of calcium supplements on femoral bone mineral density and vertebral fracture rate in vitamin-D-replete elderly patients. Osteoporosis Int 4:245–252

    Article  CAS  Google Scholar 

  • Cumming RG, Nevitt MC (1997) Calcium for prevention of osteoporotic fractures in postmenopausal women. J Bone Miner Res 12:1321–1329

    Article  PubMed  CAS  Google Scholar 

  • Curhan GC, Willett WC, Speizer FE, Spiegelman D, Stampfer MJ (1997) Comparison of dietary calcium with supplemental calcium and other nutrients as factors affecting the risk for kidney stones in women. Ann Intern Med 126:497–504

    PubMed  CAS  Google Scholar 

  • Dawson-Hughes B, Dallai GE, Krall EA, Sadowski L, Sahyoun N, Tannenbaum S (1990) A controlled trial of the effect of calcium supplementation on bone density in postmenopausal women. N Engl J Med 323:878–883

    Article  PubMed  CAS  Google Scholar 

  • Dawson-Hughes B, Harris SS, Krall EA, Dalla GE (1997) Effect of calcium and vitamin D supplementation on bone density in men and women 65 years of age and older. N Engl J Med 337:670–676

    Article  PubMed  CAS  Google Scholar 

  • Ensrud KE, Duong T, Cauley JA, Heaney RP, Wolf RL, Harris E, Cummings SR, for the Study of Osteoporotic Fractures Research Group (2000) Low fractional calcium absorption increases the risk for hip fracture in women with low calcium intake. Ann Intern Med 132:345–353

    PubMed  CAS  Google Scholar 

  • Ettinger B, Black DM, Mitlak BH, Knickerbocker RK, Nickelsen T, Genant HK, Christiansen C, Delmas PD, Zanchetta JR, Stakkestad J, Glüer CC, Krueger K, Cohen FJ, Eckert S, Ensrud KE, Avioli LV, Lips P, Cummings SR (1999) Reduction of vertebral fracture risk in postmenopausal women with osteoporosis treated with raloxifene. JAMA 282:637–645

    Article  PubMed  CAS  Google Scholar 

  • Heaney RP (1991) Calcium supplements: practical considerations. Osteoporosis Int 1:65–71

    Article  CAS  Google Scholar 

  • Heikinehimo R, Inkovaara J, Harju E, Haavisto M, Kaarela R, Kataja J, Kokko A, Kolho L, Rajala S (1992) Annual injection of vitamin D and fractures in aged bones. Calcif Tissue Int 51:105–110

    Article  Google Scholar 

  • Lips P, Graafmans WC, Ooms ME, Bezember PD, Bouter LM (1996) Vitamin D supplementation and fracture incidence in elderly persons: a randomized placebo-controlled clinical trial. Ann Intern Med 124:400–406

    PubMed  CAS  Google Scholar 

  • Matkovic V, Kostial K, Simonovic I, Buzina R, Broadarec A, Nordin BEC (1979) Bone status and fracture rates in two regions of Yugoslavia. Am J Clin Nutr 32:540–549

    PubMed  CAS  Google Scholar 

  • McAlindon TE, Felson DT, Zhang Y, Hannan MT, Aliabadi P, Weissman B, Rush D, Wilson PWF, Jacques P (1996) Relation of dietary intake and serum levels of vitamin D to progression of Osteoarthritis of the knee among participants in the Framingham study. Ann Intern Med 125:353–359

    PubMed  CAS  Google Scholar 

  • Pfeifer M, Begerow B, Nachtigall D, Hansen C, Minne HW (1998) randomized double blind study. Bone 23:175

    Google Scholar 

  • Pfeilschifter J, Schatz H (2000) Differentialdiagnose der Hyperkalzämie beim Erwachsenen. Med Klinik 95:143–150

    Article  CAS  Google Scholar 

  • Recker RR, Kimmel DB, Hinders S, Davies KM (1994) Anti-fracture efficacy of calcium in elderly women. J Bone Miner Res 9 (Suppl 1):S154

    Google Scholar 

  • Reid IR, Ames RW, Evans MC, Gamble GD, Sharpe SJ (1995) Long-term effects of calcium supplementation on bone loss and fractures in postmenopausal women: A randomized controlled trial. Am J Med 98:331–335

    Article  PubMed  CAS  Google Scholar 

  • Storm D, Eslin R, Porter ES, Musgrave K, Vereault D, Patton C, Kessenich C, Mohan S, Chen T, Holick MF, Rosen CJ (1998) Calcium supplementation prevents seasonal bone loss and changes in biochemical markers of bone turnover in elderly New England women: a randomized placebo-controlled trial. J Clin Endocrinol Metab 83:3817–3825

    Article  PubMed  CAS  Google Scholar 

  • Watson KE, Abrolat ML, Malone LL, Hoeg JM, Doherty T, Detrano R, Demer LL (1997) Active serum vitmain D levels are inversely correlated with coronary calcification. Circulation 96:1755–1760

    Article  PubMed  CAS  Google Scholar 

Download references

Authors
  1. J. Pfeilschifter
    View author publications

    You can also search for this author in PubMed Google Scholar

Editor information

Editors and Affiliations

  1. Klinik Fleetinsel, Admiralitätstr. 3, 20459, Hamburg, Deutschland

    Achim Hedtmann

  2. Albert-Schweitzer-Str. 9a, München-Unterhaching, Deutschland

    Siegfried Götte

Rights and permissions

Reprints and permissions

Copyright information

© 2002 Springer-Verlag Berlin Heidelberg

About this chapter

Cite this chapter

Pfeilschifter, J. (2002). Prophylaxe und Therapie einer Osteoporose mit Vitamin D und Calcium. In: Hedtmann, A., Götte, S. (eds) Osteoporose. Praktische Orthopädie, vol 41. Steinkopff, Heidelberg. https://doi.org/10.1007/978-3-642-57442-9_11

Download citation

  • DOI: https://doi.org/10.1007/978-3-642-57442-9_11

  • Publisher Name: Steinkopff, Heidelberg

  • Print ISBN: 978-3-7985-1300-6

  • Online ISBN: 978-3-642-57442-9

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics

Search

Navigation