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Ergänzende Untersuchungen

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Demyelinisierende Erkrankungen

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Zusammenfassung

Die ergänzenden Untersuchungen haben drei Ziele: Bei den ersten Symptomen der Erkrankung helfen sie, andere Diagnosen auszuschließen, die durch die Art ihres Auftretens eine MS vortäuschen können. Sie können dazu beitragen, die Diagnose einer MS zu sichern. In manchen Fällen ermöglichen sie, die Wirksamkeit von Therapien im Rahmen klinischer Prüfungen zu verfolgen und zu beurteilen. Meist gestattet die Gegenüberstellung von klinischen Befunden und den Befunden zusätzlicher Untersuchungen, die Diagnose zu stellen. Allerdings ergibt keine dieser zusätzlichen Untersuchungen MS-spezifische Resultate. Im Folgenden werden wir uns mit dem diagnostischen Stellenwert der evozierten Potenziale, der Untersuchung des Liquor cerebrospinalis, mit der urodynamischen Bilanz und der Kernspintomographie (MRT) beschäftigen.

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Literatur

  1. Chiappa KH (1990) Evoked potentials in clinical medicine. Raven Press, New York, p 647

    Google Scholar 

  2. Nuwer MR (1990) Evoked potentials. In: Cook SD (ed) Handbook of multiple sclerosis. Marcel Dekker, New York Basel, pp 271–290

    Google Scholar 

  3. Fischer C, Mauguière F, Ibanez V et al. (1986) Potentiels évoqués visuels, auditifs précoces, et somesthésiques dans la sclérose en plaques (917 cas). Rev Neurol 142:517–523

    CAS  PubMed  Google Scholar 

  4. Hume AL, Waxman SG (1988) Evoked potentials in suspected multiple sclerosis: diagnosis value and prediction of clinical course. J Neurol Sci 83:191–210

    Article  CAS  PubMed  Google Scholar 

  5. Poser CM, Paty DW, Scheinberg L et al. (1983) New diagnostic criteria for multiple sclerosis: guidelines for research protocols. Ann Neurol 13:227–231

    Article  CAS  PubMed  Google Scholar 

  6. Schumacher GA, Beebe GW, Kibler RF et al. (1965) Problems of experimental trials of therapy in multiple sclerosis. Ann NY Acad Sci 122:552–568

    Article  Google Scholar 

  7. Frederikson S (1994) CSF-abnormalities and MS diagnosis. Int MSJ 1:69–71

    Google Scholar 

  8. Whitaker JN, Benveniste EN, Zhou S (1990) Cerebrospinal fluid. In: Cook SD, (ed) Handbook of multiple sclerosis. Marcel Dekker, New York Basel, pp 251–270

    Google Scholar 

  9. Amarenco G (1993) Aspects cliniques et urodynamiques des troubles vésicosphinctériens neurogènes. Editions techniques. Encycl Med Chir (Paris-France), Neurologie 17–012-L-10, 5p

    Google Scholar 

  10. Fowler CJ (1994) Bladder dysfunction in multiple sclerosis: causes and treatment. Int MSJ 1:99–107

    Google Scholar 

  11. Barkhof F, Filippi M (1995) Can MRI be a predictor of long-term clinical outcome for MS? Int MSJ 2:4–9

    Google Scholar 

  12. Paty DW (1990) Neuroimaging in multiple sclerosis. In: Cook SD (ed) Handbook of multiple sclerosis. Marcel Dekker, New York Basel, pp 291–316

    Google Scholar 

  13. Lee KH, Hashimoto S, Hooge JP et al. (1991) Magnetic resonance imaging of the head in the diagnosis of multiple sclerosis: a prospective 2-year follow-up with comparison of clinical evaluation, evoked potential, oligoclonal banding, and CT. Neurology 41:657–660

    Article  CAS  PubMed  Google Scholar 

  14. Paty DW et al. (1988) MRI in the diagnosis of MS: a prospective study with comparison of clinical evaluation, evoked potentials, oligoclonal banding and CT. Neurology 38:180–185

    Article  CAS  PubMed  Google Scholar 

  15. Nauta JJP, Thompson AJ, Barkhof F et al. (1994) Magnetic resonance imaging in monitoring the treatment of multiple sclerosis patients: statistical power of parallel groups and crossover designs. J Neurol Sci 122:6–14

    Article  CAS  PubMed  Google Scholar 

  16. McFarland HF, Frank JA, Albert PS et al. (1992) Using gadolinium-enhanced magnetic resonance imaging lesions to monitor disease activity in multiple sclerosis. Ann Neurol 32:758–766

    Article  CAS  PubMed  Google Scholar 

  17. Paty DW, Li DKB (1993) Interferon ß-1b is effective in the relapsing-remitting multiple sclerosis. II. MRI analysis results of a multicenter, randomized, double-blind, placebo-controlled trial. Neurology 43:662–667

    Article  CAS  PubMed  Google Scholar 

  18. Edan G, Miller DH, Clanet M et al. (1997) Therapeutic effect of mitoxantrone combined with methylprednisolone in multiple sclerosis: a randomised multicenter study of active disease using MRI and clinical criteria. J Neurol Neurosurg Psychiatry 62:112–118

    Article  CAS  PubMed  Google Scholar 

  19. Thompson AJ, Kermode AG, MacManus DG et al. (1990) Patterns of disease activity in multiple sclerosis: clinical and magnetic resonance imaging study. Br Med J 300:631–634

    Article  CAS  Google Scholar 

  20. Van Walderveen MAA, Barkhof F, Homes OR et al. (1995) Correlating MRI and clinical disease activity in multiple sclerosis: relevance of hypointense lesions on short TR/short TE (»T1 weighted«) spin echo images. Neurology 45:1684–1690

    Article  PubMed  Google Scholar 

  21. Tourbah A, Deschamps R, Stievenart JL et al. (1996) Magnetic resonance imaging using FLAIR pulse sequence in white matter diseases. J Neuradiol 23:217–222

    CAS  Google Scholar 

  22. Tourbah A, Stievenart JL, Iba-Zizen MT et al. (1996) In vivo localized NMR proton spectroscopy of normal appearing white matter in patients with multiple sclerosis. J Neuradiol 23:49–55

    CAS  Google Scholar 

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Authors
  1. A. Tourbah
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  2. O. Lyon-Caen
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Editor information

Editors and Affiliations

  1. Neurologische Universitätsklinik, Kantonsspital Basel, Petersgraben 4, Basel, 4031, Schweiz

    Andreas J. Steck

  2. Neurologische Klinik, Universitätsklinikum Düsseldorf, Moorenstraße 5, Düsseldorf, 40225, Deutschland

    Hans-Peter Hartung  & Bernd C. Kieseier  & 

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© 2003 Springer-Verlag Berlin Heidelberg

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Tourbah, A., Lyon-Caen, O. (2003). Ergänzende Untersuchungen. In: Steck, A.J., Hartung, HP., Kieseier, B.C. (eds) Demyelinisierende Erkrankungen. Steinkopff, Heidelberg. https://doi.org/10.1007/978-3-642-57441-2_12

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  • DOI: https://doi.org/10.1007/978-3-642-57441-2_12

  • Publisher Name: Steinkopff, Heidelberg

  • Print ISBN: 978-3-642-63265-5

  • Online ISBN: 978-3-642-57441-2

  • eBook Packages: Springer Book Archive

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