Abstract
Hypoplastic left heart syndrome is the 8th most common congenital heart disease. It occurs in 0.16–0.68/1000 live births (4% of all congenital heart diseases at all ages).
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References
Aiello VD, Ho SY, Anderson RH, Thiene G (1990) Morphologic features of the hypoplastic left heart syndrome: a reappraisal. Pediatr Pathol 10:931
Akintuerk H, Michel-Behnke I, Valeske K, Mueller M, Thul J, Bauer J, Hagel KJ, Kreuder J, Vogt P, Schranz D (2002) Stenting of the arterial duct and banding of the pulmonary arteries: basis for combined Norwood stage I and II repair in hypo-plastic left heart. Circulation 105:1099–1103
Azakie T, Merklinger SL, McCrindle BW, van Arsdell GS, Lee KJ, Benson LN, Coles JG, Williams WG (2001) Evolving strategies and improving outcomes of the modified Norwood procedure: a 10-year single-institution experience. Ann Thorac Surg 72:1349–1353
Bailey LL, Nehlsen-Cannarella SL, Conception W, Jolley WB (1985) Baboon-to-human cardiac xenotransplantation in a neonate. JAMA 254:3321–3329
Bailey LL, Nehlsen-Cannarella SL, Doroshow RW, Jacobson JG, Martin RD, Allard MW, Hyde MR, Dang Bui RH, Petry EL (1986) Cardiac allotransplantation in newborn as therapy for hypoplastic left heart syndrome. N Engl J Med 315:949–951
Barnea O, Austin EH, Richman B, Santamore WP (1994) Balancing the circulation: theoretic optimisation of pulmonary/systemic flow ratio in hypoplastic left heart syndrome. J Am Coll Cardiol 24:1376–1381
Bartram U, Grunenfelder J, Van Praagh R (1997) Causes of death after the modified Norwood procedure: a study of 122 postmortem cases. Ann Thorac Surg 64:1795–1802
Bradley SM, Simsic JM, Atz AM (2001) Hemodynamic effects of inspired carbon dioxide after the Norwood procedure. Ann Thorac Surg 72:2088–2094
Chang RK, Chen AY, Klitzner TS (2002) Clinical management of infants with hypoplastic left heart syndrome in the United States, 1988–1997. Pediatrics 110:292–298
Corno AF, Mazzera E, Marino B, Picardo S, Marcelletti C (1989) Bidirectional cavopulmonary anastomosis. J Am Coll Cardiol 13:74A
Corno AF (2000) Surgery for congenital heart disease. Curr Opinion Cardiol 15:238–243
Daebritz SH, Tiete AR, Rassoulian D, Roemer U, Kozlik-Feldmann R, Sachweh J, Netz H, Reichart B (2002) Borderline hypoplastic left heart malformations: Norwood palliation or two-ventricle repair? Thorac Cardiovasc Surg 50:266–270
Ferencz C, Rubin JD, McCarter RJ (1985) Congenital heart disease: prevalence at livebirth. The Baltimore-Washington infant study. Am J Epidemiol 121:31–36
Fyler DC, Buckley LP, Hellenbrand WE, Cohn HE (1980) Report of the New England Regional Infant Care Program. Pediatrics 65(Suppl):375–461
Forbess JM, Cook N, Roth SJ, Mayer JE, Jonas RA (1995) Ten-year institutional experience with palliative surgery for hypoplastic left heart syndrome. Risk factors related to stage I mortality. Circulation 92:II-262–266
Fortuna RS, Chinnock RE, Bailey LL (1999) Heart transplantation among 233 infants during the first six months of life: the Loma Linda experience. Clin Transpl 263
Gaynor JW, Mahle WT, Cohen MI, Ittenbach RF, DeCampli WM, Steven JM, Nicolson SC, Spray TL (2002) Risk factors for mortality after the Norwood procedure. Eur J Cardiothorac Surg 22:8289
Giannico S, Corno AF, Marino B, Cicini MP, Gagliardi MG, Amodeo A, Picardo S, Marcelletti C (1992) Total extracardiac right heart bypass. Circulation 86(Suppl 2):110–117
Gibbs JL, Wren C, Watterston KG, Hunter S, Hamilton JR (1993) Stenting of the arterial duct combined with banding of the pulmonary arteries and atrial septectomy or septostomy: a new approach to palliation for the hypoplastic left heart syndrome. Br Heart J 69:551–555
Grabitz RG, Joffres MR, Collins-Nakai RL (1988) Congenital heart disease: incidence in the first year of life. The Alberta heritage pediatric cardiology program. Am J Epidemiol 128:381–388
Graziano JN, Heidelberger KP, Ensing GJ, Gomez CA, Ludomirsky A (2002) The influence of a restrictive atrial septal defect on pulmonary vascular morphology in patients with hypoplastic left heart syndrome. Pediatr Cardiol 23:146–151
Gutgesell HP, Gibson J (2002) Management of hypo-plastic left heart syndrome in the 1990s. Am J Cardiol 89:842–846
Gutgesell HP (2002) What if it were your child? Am J Cardiol 89:856
Ikle L, Hale K, Fashaw L, Boucek M, Rosenberg AA (2003) Developmental outcome of patients with hypoplastic left heart syndrome treated with heart transplantation. J Pediatr 142:20–25
Imoto Y, Kado H, Shiokawa Y, Minami K, Yasui H (2001) Experience with the Norwood procedure without circulatory arrest. J Thorac Cardiovasc Surg 122:879–882
Ishizaka T, Ohye RG, Suzuki T, Devaney EJ, Bove EL (2003) Bilateral pulmonary artery banding for resuscitation in hypoplastic left heart syndrome. Ann Thorac Surg 75:277–279
Jacobs ML, Blackstone EH, Bailey LL (1998) Intermediate survival in neonates with aortic atresia: a multi-institutional study. The Congenital Heart Surgeons Society. J Thorac Cardiovasc Surg 116:417–431
Jenkins PC, Flanagan MF, Jenkins KJ, Sargent JD, Canter CE, Chinnock RE, Vincent RN, Tosteson AN, O’Connor GT (2000) Survival analysis and risk factors for mortality in transplantation and staged surgery for hypoplastic left heart syndrome. J Am Coll Cardiol 36:1178–1185
Jonas RA, Lang P, Hansen DD, Hickey P, Castaneda AR (1986) First-stage palliation of hypoplastic left heart syndrome: the importance of coarctation and shunt size. J Thorac Cardiovasc Surg 92:6–13
Kishimoto H, Kawahira Y, Kawata H, Miura T, Iwai S, Mori T (1999) The modified Norwood palliation on a beating heart. J Thorac Cardiovasc Surg 118:1130–1132
Korkola SJ, Tchervenkov CI, Shum-Tim D (2002) Aortic arch reconstruction without circulatory arrest: review of techniques, applications, and indications. Semin Thorac Cardiovasc Surg Pediatr Card Surg Ann 5:116–125
Lev M, Arcilla R, Rimoldi HJA, Licata RH, Gasul BM (1963) Premature narrowing or closure of the foramen ovale. Am Heart J 65:638–647
Lim C, Kim WH, Kim SC, Rhyu JW, Baek MJ, Oh SS, Ny CY, Kim CW (2003) Aortic arch reconstruction using regional perfusion without circulatory arrest. Eur J Cardiothorac Surg 23:149–155
Mahle WT, Clancy RR, Moss EM, Gerdes M, Jobes DR, Wernovsky G (2000) Neurodevelopmental outcome and lifestyle assessment in school-aged and adolescent children with hypoplastic left heart syndrome. Pediatrics 105:1082–1089
Marcelletti C, Anderson RH, Becker AE, Corno AF, di Carlo DC, Mazzera E (1986) Pediatric Cardiology, Vol 6. Churchill & Livingstone, London
Marcelletti C, Corno AF, Giannico S, Marino B (1990) Inferior vena cava to pulmonary artery extracardiac conduit: a new form of right heart bypass. J Thorac Cardiovasc Surg 100:228–232
Mazzera E, Corno AF, Picardo S, Di Donato RM, Marino B, Costa D, Marcelletti C (1989) Bidirectional cavopulmonary shunts: clinical applications as staged or definitive palliation. Ann Thorac Surg 47:415–420
Migliavacca F, Pennati G, Dubini G, Fumero R, Pietrabissa R, Urcelay G, Bove EL, Hsia TY, de Leval MR (2001) Modeling of the Norwood circulation: effects of shunt size, vascular resistance, and heart rate. Am J Physiol Heart Circ Physiol 280: H-2076–2086
Milo S, Ho SY, Anderson RH (1980) Hypoplastic left heart syndrome: can this malformation be treated surgically? Thorax 35:351–354
Mitchell MB, Campbell DN, Bielefeld MR, Doremus T (2000) Utility of extracorporeal membrane oxygenation for early graft failure following heart transplantation in infancy. J Heart Lung Transplant 19:934–939
Noona JA, Nadas AS (1958) The hypoplastic left heart syndrome: an analysis of 101 cases. Pediatr Clin North Am 5:1029
Norwood WI, Lang P, Castaneda AR, Campbell DN (1981) Experience with operations for hypoplastic left heart syndrome. J Thorac Cardiovasc Surg 82:511–519
Norwood WI, Lang P, Hansen DD (1983) Physiologic repair of aortic atresia-hypoplastic left heart syndrome. N Engl J Med 308:23–26
Pigula FA (2002) Arch reconstruction without circulatory arrest: scientific basis for continued use and application to patients with arch anomalies. Semin Thorac Cardiovasc Surg Pediatr Card Surg Ann 5:104–115
Pizarro C, Norwood WI (2003) Pulmonary artery banding before Norwood procedure. Ann Thorac Surg 75:1008–1010
Pizarro C, Davis DA, Galantowicz ME, Munro H, Gidding SS, Norwood WI (2002) Stage I palliation for hypoplastic left heart syndrome in low birth weight neonates: can we justify it? Eur J Cardiothorac Surg 21:716–720
Poirier NC, Drummond-Webb JJ, Hisamochi K, Im-amura M, Harrison AM, Mee RBB (2000) Modified Norwood procedure with a high-flow cardiopulmonary bypass strategy results in low mortality without late arch obstruction. J Thorac Cardiovasc Surg 120:875–884
Rychik J, Bush DM, Spray TL, Gaynor JW, Wernovsky G (2000) Assessment of pulmonary systemic blood flow ratio after first stage palliation for hypoplastic left heart syndrome: development of a new index with the use of Doppler echocardiography. J Thorac Cardiovasc Surg 120:81–87
Ruiz CE, Gamra H, Zhang HP, Garcia EJ, Boucek MM (1993) Brief report: stenting of the ductus arteriosus as a bridge to cardiac transplantation in infants with the hypoplastic left heart syndrome. N Engl J Med 328:1605–1608
Sade RM, Crawford FA, Fyfe DA (1986) Letter to the editor: symposium on the hypoplastic left heart syndrome. J Thorac Cardiovasc Surg 91:937–939
Sano S, Ishino K, Kawada M, Fujisawa E, Kasahara S, Nakanishi K, Arai S, Hisamochi K, Kamada M, Ohtsuki S (2001) The modified Norwood operation for hypoplastic left heart syndrome using right ventricle-to-pulmonary artery shunt. Cardiol Young 11(Suppl I):21
Starnes VA, Griffin ML, Pitlick PT, Bernstein D, Baum D, Ivens K, Shumway NE (1992) Current approach to hypoplastic left heart syndrome: palliation, transplantation, or both? J Thorac Cardiovasc Surg 104:189–194
Tchervenkov CI, Korkola SJ, Shum-Tim D, Calaritis C, Laliberte E, Reyes TU, Lavoie J (2001) Neonatal aortic arch reconstruction avoiding circulatory arrest and direct arch vessel cannulation. Ann Thorac Surg 72:1615–1620
Tweddell JS, Hoffman GM, Mussatto KA, Fedderly RT, Berger S, Jaquiss RD, Ghanayem NS, Frisbee SJ, Litwin SB (2002) Improved survival of patients undergoing palliation of hypoplastic left heart syndrome: lessons learned from 115 consecutive patients. Circulation 106(Suppl I):182–189
Zeigler VL (2003) Ethical principles and parental choice: treatment options for neonates with hypoplastic left heart syndrome. Pediatr Nurs 29: 65–69
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Corno, A.F. (2003). Hypoplastic left heart syndrome. In: Congenital Heart Defects. Steinkopff, Heidelberg. https://doi.org/10.1007/978-3-642-57358-3_17
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DOI: https://doi.org/10.1007/978-3-642-57358-3_17
Publisher Name: Steinkopff, Heidelberg
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