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Spleen

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Surgery

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Abstract

The spleen has long been an organ of interest in popular as well as medical literature. Historically, the spleen has been associated with more functions than any other organ.1 Of interest, the spleen had long been associated with the ability to run, with references in ancient literature to splenectomy being performed to allow men and horses to run faster. As recently as 1922 this myth was tested in the laboratory at Johns Hopkins University, where Macht and Finesilver observed that asplenic mice were able to run faster than mice with an intact spleen.2 The ancient Greeks attributed the origin of black bile to the spleen. In the sixteenth century, Paracelsus (1490–1541) wrote that the spleen was a superfluous organ that should be excised when diseased. Vesalius (1514–1564) excised the spleens of many animals without adverse effects, supporting his contention that the spleen is not essential to life.1 A number of experimental surgeons demonstrated in the next century that animals could live without their spleens. There are a number of “case reports” from the late seventeenth century in which successful partial splenectomies are described after traumatic prolapse of the spleen through penetrating wounds.

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Authors
  1. Alan T. Lefor
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  2. Edward H. Phillips
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Editors and Affiliations

  1. University of California, San Francisco, USA

    Jeffrey A. Norton MD (Professor and Vice-Chairman of Surgery, Chief) (Professor and Vice-Chairman of Surgery, Chief)

  2. Surgical Service, San Francisco VA Medical Center, San Francisco, California, USA

    Jeffrey A. Norton MD (Professor and Vice-Chairman of Surgery, Chief) (Professor and Vice-Chairman of Surgery, Chief)

  3. Division of General Surgery, Duke University Medical Center, Durham, North Carolina, USA

    R. Randal Bollinger MD, PhD (Professor of Surgery, Professor of Immunology, Chief) (Professor of Surgery, Professor of Immunology, Chief)

  4. Division of Surgical Oncology, University of Michigan, Comprehensive Cancer Center, Ann Arbor, Michigan, USA

    Alfred E. Chang MD (Chief, Hugh Cabot Professor of Surgery) (Chief, Hugh Cabot Professor of Surgery)

  5. Department of Surgery, University of Medicine and Dentistry of New Jersey, Robert Wood Johnson Medical School, New Brunswick, New Jersey, USA

    Stephen F. Lowry MD (Professor and Chairman) (Professor and Chairman)

  6. Division of General Surgery, University of California, San Francisco, San Francisco, California, USA

    Sean J. Mulvihill MD (Professor of Surgery, Chief) (Professor of Surgery, Chief)

  7. Karmanos Cancer Institute, Wayne State University, Harper Hospital, Detroit, Michigan, USA

    Harvey I. Pass MD (Professor of Surgery and Oncology, Chief of Thoracic Oncology) (Professor of Surgery and Oncology, Chief of Thoracic Oncology)

  8. Cell Biology and Physiology, Washington University School of Medicine, St. Louis, Missouri, USA

    Robert W. Thompson MD (Associate Professor of Surgery) (Associate Professor of Surgery)

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Lefor, A.T., Phillips, E.H. (2001). Spleen. In: Norton, J.A., et al. Surgery. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-57282-1_34

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  • DOI: https://doi.org/10.1007/978-3-642-57282-1_34

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