Abstract
The ordered migration and cooperation of many different lineages of hematopoietic cells is a key requirement for the development and the responses of cells of the immune system and during an immune response. The three major hematopoietic cell types, B lymphocytes, T lymphocytes and antigen presenting cells (APC), originate from pluripotent hematopoietic cells, and develop in the primary lymphoid organs (bone marrow and thymus). Sites for positive immune responses are the secondary lymphoid organs: spleen, lymph nodes (LN), Peyer’s patches (PP) and tonsils.
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References
Adema GJ, Hartgers F, Verstraten R, de Vries E, Marland G, Menon S, Foster J, Xu Y, Nooyen P, McClanahan T, Bacon KB, Figdor CG (1997) A dendritic-cell-derived C-C chemokine that preferentially attracts naive T cells. Nature 387: 713–717
Andrew DP, Chang MS, McNinch J, Wathen ST, Rihanek M, Tseng J, Spellberg JP, Elias III CG (1998) STCP-1 (MDC) CC chemokine acts specifically on chronically activated Th2 lymphocytes and is produced by monocytes on stimulation with Th2 cytokines IL-4 and IL-13. J Immunol 161: 5027–5038
Ansel K M, McHeyzer-Williams LJ, Ngo VN, McHeyzer-Williams MG, Cyster JG (1999) In vivo-activated CD4 T cells upregulate CXC chemokine receptor 5 and reprogram their response to lymphoid chemokines. J Exp Med 190: 1123–1134
Bazan JF, Bacon KB, Hardiman G, Wang W, Soo K, Rossi D, Greaves DR, Zlotnik A, Schall TJ (1997) A new class of membrane-bound chemokine with a CX3C motif. Nature 385: 640–644
Bonecchi R, Bianchi G, Bordignon PP, D’Ambrosio D, Lang R, Borsatti A, Sozzani S, Allavena P, Gray PA, Mantovani A, Sinigaglia F (1998) Differential expression of chemokine receptors and chemotactic responsiveness of type 1 T helper cells (This) and Th2s. J Exp Med 187: 129–134
Butcher EC, Williams M, Youngman K, Rott L, Briskin M (1999) Lymphocyte trafficking and regional immunity. Adv Immunol 72: 209–253
Campbell JJ, Pan J, Butcher EC (1999) Cutting edge: developmental switches in chemokine responses during T cell maturation. J Immunol 163: 2353–2357
Chang M, McNinch J, Elias III C, Manthey CL, Grosshans D, Meng T, Boone T, Andrew DP (1997) Molecular cloning and functional characterization of a novel CC chemokine, stimulated T cell chemotactic protein (STCP-1) that specifically acts on activated T lymphocytes. J Biol Chem 272: 25229–25237
Chantry D, DeMaggio AJ, Brammer H, Raport J, Wood CL, Schweickart VL, Epp A, Smith A, Stine JT, Walton K, Tjoelker L, Godiska R, Gray PW (1998) Profile of human macrophage transcripts: insights into macrophage biology and identification of novel chemokines. J Leukoc Biol 64: 49–54
Fong AM, Robinson LA, Steeber DA, Tedder TF, Yoshie O, Imai T, Patel DD (1998) Fractalkine and CX3CR1 mediate a novel mechanism of leukocyte capture, firm adhesion, and activation under physiologic flow. J Exp Med 188: 1413–1419
Förster R, Schubel A, Breitfeld D, Kremmer E, Renner-Möller I, Wolf E, Lipp M (1999) CCR7 coordinates the primary immune response by establishing functional microenvironments in secondary lymphoid organs. Cell 99: 23–33
Galli G, Chantry D, Annunziato F, Romagnani P, Cosmi L, Lazzeri E, Manetti R, Maggi E, Gray PW, Romagnani S (2000) Macrophage-derived chemokine production by activated human T cells in vitro and in vivo: preferential association with the production of type 2 cytokines. Eur J Immunol 30: 204–210
Godiska R, Chantry D, Raport CJ, Sozzani S, Allavena P, Leviten D, Mantovani A, Gray PW (1997) Human macrophage-derived chemokine (MDC), a novel chemoattractant for monocytes, monocyte-derived dendritic cells, and natural killer cells. J Exp Med 185: 1595–1604
Gonzalo JA, Pan Y, Lloyd CM, Jia GQ, Yu G, Dussault B, Powers CA, Proudfoot AE, Coyle AJ, Gearing DGutierrez-Ramos JC (1999) Mouse monocyte-derived chemokine is involved in airway hyperreactivity and lung inflammation. J Inununol 163: 403–411
Gunn MD, Tangemann K, Tam C, Cyster JG, Rosen SD, Williams LT (1998a) A chemokine expressed in lymphoid high endothelial venules promotes the adhesion and chemotaxis of naive T lymphocytes. Proc Natl Acad Sci U S A 95: 258–263
Gunn MD, Ngo VN, Ansel KM, Ekland EH, Cyster JG, Williams LT (1998b) A B-cell-homing chemokine made in lymphoid follicles activates Burkitt’s lymphoma receptor-1. Nature 391: 799–803
Harrison JK, Jiang Y, Chen S, Xia Y, Maciejewski D, McNamara RK, Streit WJ, Salafranca MN, Adhikari S, Thompson DA, Botti P, Bacon KB, Feng L (1998) Role for neuronally derived fractalkine in mediating interactions between neurons and CX3CR1-expressing microglia. Proc Natl Acad Sci U S A 95: 10896–10901
Imai T, Baba M, Nishimura M, Kakizaki M, Takagi S, Yoshie 0 (1997) The T cell-directed CC chemokine TARC is a highly specific biological ligand for CC chemokine receptor 4. J Biol Chem 272: 15036–15042
Imai T, Chantry D, Raport CJ, Wood CL, Nishimura M, Godiska R, Yoshie 0, Gray PW (1998) Macrophage-derived chemokine is a functional ligand for the CC chemokine receptor 4. J Biol Chem 273: 1764–1768
Imai T, Hieshima K, Haskell C, Baba M, Nagira M, Nishimura M, Kakizaki M, Takagi S, Nomiyama H, Schall TJ, Yoshie 0 (1997) Identification and molecular characterization of fractalkine receptor CX3CR1, which mediates both leukocyte migration and adhesion. Cell 91: 521–530
Imai T, Nagira M, Takagi S, Kakizaki M, Nishimura M, Wang J, Gray PW, Matsushima K, Yoshie 0 (1999) Selective recruitment of CCR4-bearing Th2 cells toward antigen-presenting cells by the CC chemokines thymus and activation-regulated chemokine and macrophage-derived chemokine. Int Immunol 11: 81–88
Imai T, Yoshida T, Baba M, Nishimura M, Kakizaki M, Yoshie O (1996) Molecular cloning of a novel T cell-directed CC chemokine expressed in thymus by signal sequence trap using Epstein-Barr virus vector. J Biol Chem 271: 21514–21521
Kanazawa N, Nakamura T, Tashiro K, Muramatsu M, Morita K, Yoneda K, Inaba K, Imamura S, Honjo T (1999) Fractalkine and macrophage-derived chemokine: T cell-attracting chemokines expressed in T cell area dendritic cells. Eur J Immunol 29: 1925–1932
Legler DF, Loetscher M, Roos S, Clark-Lewis I, Baggiolini M, Moser B (1998) B cell-attracting chemokine 1, a human CXC chemokine expressed in lymphoid tissues, selectively attracts B lymphocytes via BLR1/CXCR5. J Exp Med 187: 655–660
Lieberam I, Förster I (1999) The murine beta-chemokine TARC is expressed by subsets of dendritic cells and attracts primed CD4+ T cells. Eur J Immunol 29: 2684–2694
Lloyd CM, Delaney T, Nguyen T, Tian J, Martinez AC, Coyle AJ, Gutierrez-Ramos JC (2000) CC chemokine receptor (CCR)3/Eotaxin is followed by CCR4/Monocyte-derived chemokine in mediating pulmonary T helper lymphocyte type 2 recruitment after serial antigen challenge in vivo. J Exp Med 191: 265–274
Maciejewski-Lenoir D, Chen S, Feng L, Maki R, Bacon KB (1999) Characterization of fractalkine in rat brain cells: migratory and activation signals for CX3CR-1-expressing microglia. J Immunol 163: 1628–1635
Melchers F, Rolink AG, Schaniel C (1999) The role of chemokines in regulating cell migration during humoral immune responses. Cell 99: 351–354
Nomiyama H, Imai T, Kusuda J, Miura R, Callen DF, Yoshie 0 (1997) Assignment of the human CC chemokine gene TARC (SCYA17) to chromosome 16813. Genomics 40: 211–213
Pan Y, Lloyd C, Zhou H, Dolich S, Deeds J, Gonzalo JA, Vath J, Gosselin M, Ma J, Dussault B, Woolf E, Alperin G, Culpepper J, Gutierrez-Ramos JC, Gearing D (1997) Neurotactin, a membrane-anchored chemokine upregulated in brain inflammation. Nature 387: 611–617
Rodenburg RJ, Brinkhuis RF, Peek R, Westphal JR, Van Den Hoogen FH, van Venrooij WJ, van de Putte LB (1998) Expression of macrophage-derived chemokine (MDC) mRNA in macrophages is enhanced by interleukin- 1 beta, tumor necrosis factor alpha, and lipopolysaccharide. J Leukoc Biol 63: 606–611
Ross R, Ross XL, Ghadially H, Lahr T, Schwing J, Knop J, Reske-Kunz AB (1999) Mouse langerhans cells differentially express an activated T cell-attracting CC chemokine. J Invest Dermatol 113: 991–998
Rossi DL, Hardiman G, Copeland NG, Gilbert DJ, Jenkins N, Zlotnik A, Bazan JF (1998) Cloning and characterization of a new type of mouse chemokine. Genomics 47: 163–170
Sallusto F, Lenig D, Mackay CR, Lanzavecchia A (1998a) Flexible programs of chemokine receptor expression on human polarized T helper 1 and 2 lymphocytes. J Exp Med 187: 875–883
Sallusto F, Schaerli P, Loetscher P, Schaniel C, Lenig D, Mackay CR, Qin S, Lanzavecchia A (1998b) Rapid and coordinated switch in chemokine receptor expression during dendritic cell maturation. Eur J Immunol 28: 2760–2769
Schaniel C, Pardali E, Sallusto F, Speletas M, Ruedl C, Shimizu T, Seidl T, Andersson J, Melchers F, Rolink AG, Sideras P (1998) Activated murine B lymphocytes and dendritic cells produce a novel CC chemokine which acts selectively on activated T cells. J Exp Med 188: 451–463
Schaniel C, Sallusto F, Ruedl C, Sideras P, Melchers F, Rolink AG (1999) Three chemokines with potential functions in T lymphocyte-independent and -dependent B lymphocyte stimulation. Eur J Immunol 29: 2934–2947
Springer TA (1994) Traffic signals for lymphocyte recirculation and leukocyte emigration: the multistep paradigm. Cell 76: 301–314
Tang HL, Cyster JG (1999) Chemokine up-regulation and activated T cell attraction by maturing dendritic cells. Science 284: 819–822
Zlotnik A, Morales J, Hedrick JA (1999) Recent advances in chemokines and chemokine receptors. Crit Rev Immunol 19: 1–47
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Schaniel, C., Melchers, F., Rolink, A.G. (2000). The Cluster of ABCD Chemokines which Organizes T Cell-Dependent B Cell Responses. In: Melchers, F. (eds) Lymphoid Organogenesis. Current Topics in Microbiology and Immunology, vol 251. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-57276-0_23
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DOI: https://doi.org/10.1007/978-3-642-57276-0_23
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