Zusammenfassung
Die Muskulatur des Menschen beträgt 40% des Körpergewichts, und trotz ihrer lebensnotwendigen Funktion bestehen nur unzureichende molekulare Kenntnisse über den ultrastrukturellen Aufbau. Elektronenmikroskopische und histochemische Untersuchungen konnten bisher im quergestreiften und glatten Muskel lediglich das kontraktile Filamentsystem Aktin und Myosin nachweisen. Muskelkontraktion kommt dadurch zustande, daß diese beiden Filamentsysteme ineinander gleiten, ohne sich dabei zu verkürzen (Huxley u. Hanson 1954). Das bisher bekannte Zweifilamentsystem der Muskulatur (Aktin und Myosin) kann die erheblichen physikalischen Unterschiede der 200 verschiedenen Muskelarten des Menschen nicht erklären, so daß die Existenz noch weiterer kontraktiler Filamentsysteme vermutet wurde.
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Labeit, D. (2000). Molekularbiologische Ursachen der vorzeitigen Wehentätigkeit. In: Friese, K., Plath, C., Briese, V. (eds) Frühgeburt und Frühgeborenes. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-57222-7_3
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