Zusammenfassung
Mit der Geburt eines Kindes ist eine Kreislaufumstellung verbunden, bei der ein wesentliches Element der Verschluß des Ductus arteriosus ist. Dieser erfolgt durch zwei unabhängige Mechanismen: die direkte Einwirkung der ansteigenden Sauerstoffkonzentration des Blutes auf das Ductusgewebe und der Abfall von Hormonen und lokalen Mediatoren (Prostaglandin E2, Prostazyklin u.a. ) und damit ein Entzug der aktiven Relaxation.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
Literatur
Bömelburg T, Jorch G (1989) Abnormal blood flow patterns in renal arteries of small preterm infants with patent ductus arteriosus detected by Doppler ultrasonography. Eur J Pediatr 148: 660–664
Brook MM, Heymann MA (1995) Patent ductus arteriosus In: Emmanouilides GC, Riemenschneider TA, Allen HD, Gutgesell HP (eds) Heart disease in infants, children and adolescents. Williams & Wilkins, Baltimore, pp 746–764
Clyman RI, Brett C, Mauray R (1980) Circulating prostaglandin E2 concentration and incidence of patent ductus arteriosus in pre-term infants with respiratory distress syndrome. Pediatrics 66: 725–729
Clyman RI (1995) Problems associated with the preterm infant. In: Emmanouilides GC, Riemenschneider TA, Allen HD, Gutgesell HP (eds) Heart disease in infants, children and adolescents. Williams & Wilkins, Baltimore, pp 575–599
Dudell GG, Gersony WM (1984) Patent ductus arteriosus in neonates with severe respiratory disease. J Pediatr 104: 915–920
Friedman Z, Demers LM (1978) Essential fatty acids, prostaglandins and respiratory distress syndrome of the newborn. Pediatrics 61: 341–347
Gentile R, Stevenson GM, Dooley T, Franklin D, Kawabori I, Pearlman A (1981) Pulsed Doppler-echocardiographic determination of time of ductal closure in normal newborn infants. J Pediatr 98: 443–448
Heymann MA, Rudolph AM, Silverman NH (1976) Closure of the ductus arteriosus in premature infants by inhibition of prostaglandin synthesis. N Engl J Med 295: 530–533
Leititis J, Burghard R, Gordjani N, Wildberg A, Seybert H, Brandis M (1987) Effect of a modified fluid therapy on renal function during indomethacin therapy for persistent ductus arteriosus. Acta Paediatr 76: 789–794
Lucas A, Mitchell MD (1978) Plasma prostaglandins in pre-term neonates before and after treatment for patent ductus arteriosus. Lancet 2: 130–132
Mitchell, MD (1978) Selective elevation of circulating prostaglandin concentrations in hyaline membrane disease in pre-term infants. Prostaglandins Med 1: 207–212
McMurphy DM, Boreus LO (1971) Studies on the pharmacology of the perfused human fetal ductus arteriosus. Am J Obstet Gynecol 109: 937–942
Neubauer AP, Müller-Deike K (1995) Verschluß des haemodynamisch wirksamen persistierenden Ductus Botallo (PDA) beim Frühgeborenen unter 1000 g mit Indometacin. Monatsschr Kinderheilkd 143: 1224–1230
Shimada S, Kasai T, Konishi M, Fujiwara T (1994) Effects of patent ductus arteriosus on left ventricular ouput and blood flows in preterm infants with respiratory distress syndrome treated with surfactant. J Pediatr 125: 270–277
Siassi B, Blanco C, Cabal LA, Coran AG (1976) Incidence and clinical features of patent ductus arteriosus in low birth weight infants: A prospective analysis of 150 consecutively born infants. Pediatrics 57: 347–352
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2000 Springer-Verlag Berlin Heidelberg
About this chapter
Cite this chapter
Kienast, W., Uhlemann, M., Bartolomaeus, G. (2000). Die Problematik des Ductus arteriosus beim Frühgeborenen. In: Friese, K., Plath, C., Briese, V. (eds) Frühgeburt und Frühgeborenes. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-57222-7_20
Download citation
DOI: https://doi.org/10.1007/978-3-642-57222-7_20
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-642-63046-0
Online ISBN: 978-3-642-57222-7
eBook Packages: Springer Book Archive