Skip to main content
SpringerLink
Log in

Ophthalmika

  • Chapter
Arzneiverordnungs-Report 1999

Zusammenfassung

Die Indikationsgruppe der Ophthalmika umfaßt Präparate, die lokal oder in einzelnen Fällen auch systemisch bei Augenkrankheiten gegeben werden. Solche Präparate werden ganz überwiegend von Ophthalmologen, daneben vor allem von Allgemeinmedizinern verordnet (vgl. Kapitel 52). Sie erreichen hohe Verordnungszahlen, tragen aber wegen günstiger Kosten zu den Gesamtumsätzen des Arzneimittelmarktes weniger bei. Insgesamt hat es 1998 bei den Verordnungen von Ophthalmika deutliche Rückgänge gegeben, die im Mittel fast 6 % betrugen, bei einzelnen Präparaten jedoch erheblich höher ausfielen. Diesem abnehmenden Trend haben sich im wesentlichen Neuerungen, wie die Glaukommittel Trusopt, Alphagan, Xalatan, das Antiallergikum Alomide, der Filmbildner Liposic sowie die Gyrasehemmstoffe entzogen (Tabelle 38.1).

Verordnungen von Ophthalmika 1998 DDD der 2000 meistverordneten Arzneimittel

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 54.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 69.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

Literatur

  • Alward W.L.M. (1998): Medical management of glaucoma. N. Engl. J. Med. 339: 1298–1307.

    Article  PubMed  CAS  Google Scholar 

  • Balfour J.A., Wilde M.I. (1997): Dorzolamide. A review of ist pharmacology and therapeutic potential in the management of glaucoma and ocular hypertension. Drugs Aging 19: 384–403.

    Article  Google Scholar 

  • Behrens-Baumann W., Begall T. (1993): Antisepties versus antibiotics in the treatment of the experimental conjunctivitis caused by Staphylococcus aureus. Ger. J. Ophthalmol. 2: 409–411.

    PubMed  CAS  Google Scholar 

  • Dechant K.L., Goa K.L. (1991): Levocabastine. A review of its pharmacologieal properties and therapeutic potential as a topieal antihistamine in allergic rhinitis and conjunctivitis. Drugs 41: 202–224.

    Article  PubMed  CAS  Google Scholar 

  • Erb C., Horn A., Günthner A., Saal J.G., Thiel H.J. (1996): Psychosomatische Aspekte bei Patienten mit primärer Keratoconjunctivitis sicca. Klin. Monatsbl. Augenheilkd. 208: 96–9.

    Article  PubMed  CAS  Google Scholar 

  • Everett S.L., Kowalski R.P., Karenchak L.M., Landsittel D., Day R., Gordon Y.L. (1995): An in vitro comparison of the susceptibilities of bacterial isolates from patients with conjunctivitis and blepharitis to newer and established topieal antibiotics. Cornea 14: 382–387.

    Article  PubMed  CAS  Google Scholar 

  • Fahy G.T., Easty D.L., Collum L.M., Benediet-Smith A., Hillery M., Parsons D.G. (1992): Randomised double-masked trial of lodoxamide and sodiumcromoglycate in allergie eye disease. A multieentre study. Eur. J. Ophthalmol. 1992: 144–149.

    Google Scholar 

  • Fraunfelder F.T., Bagby G.C. (1983): Ocular chloramphenicol and aplastic anemia. N. Engl. J. Med. 308: 1536.

    PubMed  CAS  Google Scholar 

  • Geisthövel W. (1984): Hyperthyreose nach jodhaitigen Augentropfen. Dtsch. Med. Wochenschr. 109: 1304–1305.

    PubMed  Google Scholar 

  • Göbbels M., Gross D. (1996): Klinische Studie der Wirksamkeit einer Dexpanthenol-haltigen künstlichen Tränenflüssigkeit (Siccaprotect) bei der Behandlung des trockenen Auges. Klin. Monatsbl. Augenheilkd. 209: 84–88.

    Article  PubMed  Google Scholar 

  • Haas A., Trummer G., Eckhardt M., Schmut O., Uyguner I., Pfeiffer K.P. (1995): Einfluß von Kalziumdobesilat auf die Progression der diabetischen Retinopathie. Klin. Monatsbl. Augenheilkd. 207: 17–21.

    Article  PubMed  CAS  Google Scholar 

  • Hammann C., Kammerer R., Gerber M., Spertini F. (1996): Comparison of effects of topieallevocabastine and nedocromil sodium on the early response in a conjunctival provocation test with allergen. J. Allergy Clin. Immunol. 98: 1045–1050.

    Article  PubMed  CAS  Google Scholar 

  • Hanioglu-Kargi S., Basci N., Soysal H., Bozkurt A., Gursei E., Kayaalp O. (1998): The penetration of ofloxacin into human aqueous humor given by various routes. Eur. J. Ophthalmol. 8: 33–36.

    PubMed  CAS  Google Scholar 

  • Heijl A., Strahlman E., Sverrisson T., Brinchman-Hansen O., Puustjarvi T., Tipping R. (1997): A comparison of dorzolamide and timolol in patients with pseudoexfoliation and glaucoma or ocular hypertension. Ophthalmology 104: 137–142.

    Article  PubMed  CAS  Google Scholar 

  • Hertel F., Pfeiffer N. (1994): Einzeldosisapplikationen in der Glaukomtherapie. Ophthalmologe 91: 602–605.

    PubMed  CAS  Google Scholar 

  • Hingorani M., Lightman S. (1995): Therapeutie options in ocular allergic disease. Drugs 50: 208–221.

    Article  PubMed  CAS  Google Scholar 

  • Ibanez M.D., Laso M.T., Martinez San Irineo M., Alonso E. (1996): Anaphylaxis to disodium cromoglycate. Ann. Allergy Asthma Immunol. 77: 185–186.

    Article  PubMed  CAS  Google Scholar 

  • Jensen H.G., Felix C. (1998): In vitro antibiotie susceptibilities of ocular isolates in North and South America. In vitro antibiotic testing group. Cornea 17: 79–87.

    Article  PubMed  CAS  Google Scholar 

  • Johnstone M.A. (1997): Hypertrichosis and increased pigmentation of eyelashes and adjacent hair in the region of the ipsilateral eyelids of patients treated with unilateral topieallatanoprost. Am. J. Ophthalmol. 124: 544–547.

    PubMed  CAS  Google Scholar 

  • Kampik A., Meßmer E., Thoma K. (1996): Das Auge-Konjunktivitis und Sicca Syndrom. Schriftenreihe der Bayerischen Landesapothekerkammer, Heft 53.

    Google Scholar 

  • Kjellman N.I., Stevens M.T. (1995): Clinical experience with Tilavist: an overview of efficacy and safety. Allergy 50: 14–22.

    Article  PubMed  CAS  Google Scholar 

  • Maus T.L., Larsson L.I., McLaren J.W., Brubaker R.F. (1997): Comparison of dorzolamide and acetazolamide as suppressors of aqueous humor flow in humans. Arch. Ophthalmol. 115: 45–49.

    Article  PubMed  CAS  Google Scholar 

  • McLeod S.D., Kolahdouz-Isfahani A., Rostamian K., Flowers C.W., Lee P.P., McDonnell P.T. (1996): The role of smears, cultures, and antibiotic sensitivity testing in the management of suspected infectious keratitis. Ophthalmology 103: 23–28.

    Article  PubMed  CAS  Google Scholar 

  • Miehels-Rautenstrauß K., Rautenstrauß B., Mardin C.Y., Budde W., Pfeiffer R.A. (1997): Genetische Grundlagen der Glaukome. Dt. Ärzteblatt A-2996–3000.

    Google Scholar 

  • Moroi S.E., Liehter P.E. (1996): Ocular Pharmacology. In: Hardman J.G., Limbird L.E. (eds.): Goodman & Gilman’s The Pharmacological Basis of Therapeutics, 9th ed., McGraw-Hill, New York, pp. 1619–1645.

    Google Scholar 

  • Noble S., McTavish D. (1995): Levocabastine. An update of its pharmacology, clinical efficacy and tolerability in the topieal treatment of allergie rhinitis and conjunctivitis. Drugs 50: 1032–1049.

    Article  PubMed  CAS  Google Scholar 

  • Nordlund J.R., Pasquale L.R., Robin A.L. et al. (1995): The cardiovascular, pulmonary, and ocular hypotensive of 0.2 % brimonidine. Arch. Ophthalmol. 113: 77–83.

    Article  PubMed  CAS  Google Scholar 

  • O’Brien T.P., Maguire M.G., Fink N.E., Alfonso E., McDonnell P. (1995): Efficacy of ofloxacin vs cefazolin and tobramycin in the therapy for bacterial keratitis. Arch. Ophthalmol. 113: 1257–1265.

    Article  PubMed  Google Scholar 

  • Ooishi M., Miyao M. (1997): Antibiotic sensitivity of recent clinical isolates from patients with ocular infections. Ophthalmologica 211, Suppl. 1, 15–24.

    Article  PubMed  CAS  Google Scholar 

  • Patel S.S., Spencer C.M. (1996): Latanoprost. A review of ist pharmacological properties, clinical efficacy and tolerability in the management of primary openangle glaucoma. Drugs Aging 9: 363–378.

    Article  PubMed  CAS  Google Scholar 

  • Pfeiffer N. (1996): Lokaler Carboanhydrasehemmer Dorzolamid: Entwicklung und Eigenschaften. Ophthalmologe 93: 103–118.

    PubMed  CAS  Google Scholar 

  • Pfeiffer N. (1998): Moderne medikamentöse Glaukomtherapie. Dtsch. Ärztebl. 95:A3292–A3297.

    Google Scholar 

  • Quigley H.A. (1996): Number of people with glaucoma worldwide. Brit. J. Ophthalmol. 80: 389–393.

    Article  CAS  Google Scholar 

  • Schuman J.S. (1996): Clinical experience with brimonidine 0.2 % and timolol 0.5 % in glaucoma and ocular hypertension. Surv. Ophthalmol. 41 (Suppl.) S27–37.

    Article  Google Scholar 

  • Sorensen S.J., Abel S.R. (1996): Comparison of the ocular beta-blockers. Ann. Pharmacother. 30: 43–54.

    PubMed  CAS  Google Scholar 

  • Stone E.M., Fingert J.H., Alward W.L.M. et al. (1997): Identification of a gene that causes primary open angle glaucoma. Science 275: 668–670.

    Article  PubMed  CAS  Google Scholar 

  • Strahlman E., Tipping R., Vogel R. (1995): A double-masked, randomized l-year study comparing dorzolamide (Trusopt), timolol, and betaxolol. International dorzolamide study group. Arch. Ophthalmol. 113: 985–986.

    Article  Google Scholar 

  • Straub W. (1986): Wann sind Kortikosteroide bei Augenerkrankungen indiziert? Dtsch. Ärztebl. 83: 2935–2937.

    Google Scholar 

  • Strempel I. (1994): Zum Problem des “Trockenen Auges„. Dtsch. Ärztebl. 91: C-204–208.

    Google Scholar 

  • Walters T.R. (1996): Development and use of brimonidine in treating acute and chronic elevations of intraocular pressure: a review of safety, efficacy, dose response, and dosing studies. Surv. Ophthalmol. 41: SI9–S26.

    Article  Google Scholar 

  • Watson P., Stjernschantz J., Latanoprost Study Group (1996): A six-month, randomized, double-masked study comparing latanoprost with timolol in open-angle glaucoma and ocular hypertension. Ophthalmology 103: 126–137.

    Article  PubMed  CAS  Google Scholar 

  • Wright M., Butt Z., McIlwaine G., Fleck B. (1997): Comparison of the efficacy of diclofenac and betamethasone following strabismus surgery. Brit. J. Ophthalmol. 81: 299–301.

    Article  CAS  Google Scholar 

Download references

Authors
  1. M. J. Lohse
    View author publications

    You can also search for this author in PubMed Google Scholar

Editor information

Editors and Affiliations

  1. Pharmakologisches Institut, Universität Heidelberg, Im Neuenheimer Feld 366, 69120, Heidelberg, Deutschland

    Ulrich Schwabe

  2. Bachstraße 29, 50858, Köln, Deutschland

    Dieter Paffrath

Rights and permissions

Reprints and permissions

Copyright information

© 2000 Springer-Verlag Berlin Heidelberg

About this chapter

Cite this chapter

Lohse, M.J. (2000). Ophthalmika. In: Schwabe, U., Paffrath, D. (eds) Arzneiverordnungs-Report 1999. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-57215-9_39

Download citation

  • DOI: https://doi.org/10.1007/978-3-642-57215-9_39

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-66376-8

  • Online ISBN: 978-3-642-57215-9

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics

Search

Navigation