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Alkoholische Hepatitis

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Klinische Gastroenterologie und Stoffwechsel

Zusammenfassung

Die alkoholische Hepatitis (AH) ist eine durch Alkohol initiierte Lebererkrankung mit typischen morphologischen, klinischen und laborchemischen Besonderheiten. In der Pathogenese spielen Stoffwechselprodukte des Alkohols, wie Radikale, Acetaldehyde und Reduktionsäquivalente eine wichtige Rolle. Entscheidend ist die Aktivierung des Immunsystems durch Neoantigene und Endotoxine. Die Erkrankung läßt sich eindeutig nur mittels Leberbiopsie erfassen. Hierbei sind morphologisch die Infiltration neutrophiler, polymorphkerniger Leukozyten, das Auftreten von Mallory-Bodies und das „ballooning“ der Hepatozyten besonders charakteristisch.

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Authors
  1. H. K. Seitz
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  2. C. M. Oneta
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Editor information

Editors and Affiliations

  1. Abt. Innere Medizin I, Universitätsklinik Ulm, 89070, Ulm, Germany

    G. Adler

  2. Departement Innere Medizin Abt. Gastroenterologie Kantonsspital Basel, Universitätskliniken, Petersgraben 4, 4031, Basel, Schweiz

    C. Beglinger

  3. Abt. Gastroenterologie und Hepatologie Zentrum Innere Medizin und Dermatologie, Medizinische Hochschule Hannover, Carl-Neuberg-Straße 1, 30625, Hannover, Germany

    M. P. Manns

  4. Abt. für Innere Medizin, Park-Klinik Weißensee, Schönstraße 80, 13086, Berlin, Germany

    S. Müller-Lissner

  5. Medizinische Universitätsklinik Knappschaftskrankenhaus, In der Schornau 23-25, 44892, Bochum, Germany

    W. Schmiegel

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© 2000 Springer-Verlag Berlin Heidelberg

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Seitz, H.K., Oneta, C.M. (2000). Alkoholische Hepatitis. In: Adler, G., Beglinger, C., Manns, M.P., Müller-Lissner, S., Schmiegel, W. (eds) Klinische Gastroenterologie und Stoffwechsel. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-57194-7_43

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  • DOI: https://doi.org/10.1007/978-3-642-57194-7_43

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-65059-1

  • Online ISBN: 978-3-642-57194-7

  • eBook Packages: Springer Book Archive

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