Discussion

Abstract

The method of computer simulation is particularly suitable for the analysis of the pressure transmission in joints and for the functionally adaptive processes of the connective tissues because the mechanical stresses and strains can be calculated for locations that are not accessible to direct artifact-free measurement (for instance, the subchondral bone). Single factors, which cannot be modulated experimentally (such as fine differences in congruity/incongruity), can be isolated and varied in a complex system and investigated parametrically. Furthermore, biological processes such as the remodeling of bone, which would take up months of an experimental investigation, can be tested efficiently within reasonable periods of time.