Abstract
Dysthyroid orbitopathy, also known as Graves’ ophthalmopathy, is an autoimmune disorder characterized by the deposition of anti-thyroglobulin immune complexes in the extraocular muscles [1, 18, 19, 28]. The immune complexes induce an inflammatory response that results in fibrosis, edema and hypertrophy of the extraocular muscles and orbital fat. Furthermore, stimulation of myogenous fibroblast activity results in orbital volume, manifested primarily as proptosis. Given the relatively small volume of the orbit (26 cm3), an increase of only 4 cm3 of orbital volume (16%) will result in 6 mm of Proptosis [10].
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Hwang, P.H., Kennedy, D.W. (2000). Endoscopic Transnasal Orbital Decompression. In: Stamm, A.C., Draf, W. (eds) Micro-endoscopic Surgery of the Paranasal Sinuses and the Skull Base. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-57153-4_36
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DOI: https://doi.org/10.1007/978-3-642-57153-4_36
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