Abstract
Wounds are heterogeneous and the wound healing process is of a multifac torial nature, influenced by many factors and compounds, introduced externally. Throughout history, humans have searched for materials to promote wound healing. A great variety of preparations and products have been used, ranging from hot oils, papyri and waxes of the Egyptians to the cotton and gauze tissues which are still used (Majno 1976). Until the 1960s, there had been a minimum of research and development into wound management products, and very few of the products have been shown to be of great benefit. However, since the understanding of wound-healing biology has advanced, it may now be the time when the rational design of effective drugs to promote healing is a real possibility (Folkman 1992).
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Gottrup, F., Ă…gren, M., Karlsmark, T. (2000). Wound Healing. In: Gabard, B., Surber, C., Elsner, P., Treffel, P. (eds) Dermatopharmacology of Topical Preparations. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-57145-9_25
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