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Osteochondrodysplasien Genetisch bedingte Störungen der Skelettentwicklung

  • Bernhard Zabel
  • Andreas Winterpacht
Part of the Handbuch der Molekularen Medizin book series (HDBMOLEK, volume 7)

Zusammenfassung

Bei der Krankheitsgruppe der Osteochondrodysplasien handelt es sich um genetisch bedingte, generalisierte Entwicklungsstörungen des Knorpel-Knochen-Gewebes. Ihre Gesamthßufigkeit liegt bei etwa 4:10000–10:10000, wobei die Gruppe hunderte z. T. sehr seltener Krankheiten umfasst. Ihre Heterogenitßt erklßrt sich aus der Vielzahl von involvierten Genen, Molekülen, Proteininteraktionen, Zellen und Gewebsbereichen, die an der Bildung, dem Wachstum und der Homöostase des Skeletts beteiligt sind und deren Störung zu einem jeweils anderen Krankheitsbild führen kann.

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Copyright information

© Springer-Verlag Berlin Heidelberg 2000

Authors and Affiliations

  • Bernhard Zabel
  • Andreas Winterpacht

There are no affiliations available

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