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Molekularmedizinische Grundlagen von hereditären Tumorerkrankungen pp 43–55Cite as

Familiäres Melanom

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Part of the book series: Molekulare Medizin ((MOLMED))

Zusammenfassung

Bereits 1820 wurde von W. A. Norris ein erster Fall eines familiären Melanoms in englischer Sprache beschrieben (Norris 1820). Dabei wurde bereits herausgestellt, dass familiär auffällige Muttermale vorhanden waren, und eine Erblichkeit des Tumorleidens angenommen:

„It is remarkable that this gentleman’s father, about thirty years ago, died of a similar disease. A surgeon of this town attended him, and he informed me that a number of small tumours appeared between the shoulders… This tumour, I have remarked, originated in a mole, and it is worth mentioning, that not only my patient, and his children had many moles on various parts of their bodies, but also his own father and brothers had many of them. The youngest son had one of these marks exactly in the same place where the disease in his father first manifested itself. These facts, together with a case that has come under my notice, rather similar, would incline me to believe that this disease is hereditary.“ (Norris 1820).

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Authors and Affiliations

  1. Sektion für Dermatologische Onkologie, Universitätshautklinik, Liebermeisterstraße 25, 72076, Tübingen

    Prof. Dr. Claus Garbe & Dr. Birgit Schittek

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  1. Prof. Dr. Claus Garbe
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  2. Dr. Birgit Schittek
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  1. Max-Delbrück-Centrum für Molekulare Medizin (MDC), Robert-Rössle-Str. 10, 13122, Berlin-Buch

    Detlev Ganten  & Klaus Ruckpaul  & 

  2. Medizinische Universitätsklinik, Knappschaftskrankenhaus, In der Schornau 23-25, 44892, Bochum-Langendreer

    Stephan A. Hahn  & Wolff Schmiegel  & 

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Garbe, C., Schittek, B. (2001). Familiäres Melanom. In: Ganten, D., Ruckpaul, K., Hahn, S.A., Schmiegel, W. (eds) Molekularmedizinische Grundlagen von hereditären Tumorerkrankungen. Molekulare Medizin. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-56889-3_4

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  • DOI: https://doi.org/10.1007/978-3-642-56889-3_4

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-63219-8

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