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Retinoblastom

  • Dietmar R. Lohmann
  • Bernhard Horsthemke
  • Norbert Bornfeld
Part of the Molekulare Medizin book series (MOLMED)

Zusammenfassung

Das Retinoblastom ist der häufigste bösartige Augentumor des Kindesalters. Die Angaben zur Häufigkeit dieses Tumors schwanken und reichen von 1∶15000–1∶33 000 lebend geborene Kinder (Suckling et al. 1982; Vogel 1979). Eine Abhängigkeit von ethnischen und geografischen Faktoren oder vom Geschlecht des Kinds ist nicht erkennbar. Es gibt keine gesicherten Hinweise dafür, dass Umweltfaktoren bei der Entstehung dieses Tumors eine Rolle spielen (Buckley 1992). Insbesondere wurde kein Anstieg der Zahl der Erkrankungen im Zusammenhang mit der von den Atombomben-explosionen in Nagasaki und Hiroshima ausgehenden Strahlung festgestellt (Amemiya et al. 1993). Werden die Häufigkeiten des Retinoblastoms in verschieden lange zurückliegenden Erfassungszeiträumen verglichen, scheint eine Tendenz zur Zunahme zu bestehen. Dieser Anstieg ist wahrscheinlich durch die zunehmend vollständigere Erfassung von Erkrankungsfällen bedingt.

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Copyright information

© Springer-Verlag Berlin Heidelberg 2001

Authors and Affiliations

  • Dietmar R. Lohmann
    • 1
  • Bernhard Horsthemke
    • 1
  • Norbert Bornfeld
    • 2
  1. 1.Institut für HumangenetikUniversitätsklinikum EssenEssen
  2. 2.AugenklinikUniversitätsklinikum EssenEssen

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