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Tumorerkrankungen — Einführung aus genetischer Sicht

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Molekularmedizinische Grundlagen von hereditären Tumorerkrankungen

Part of the book series: Molekulare Medizin ((MOLMED))

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Zusammenfassung

Jede der etwa 100 verschiedenen Formen von Krebs (maligne Tumoren) ist das Ergebnis von grundlegenden, zelluläre Funktionen betreffenden Veränderungen von genetischen Informationen in den Tumorzellen. In diesem Sinn ist Krebs genetisch bedingt. Jedoch sind die meisten Formen von Krebs nicht erblich, von wichtigen Ausnahmen abgesehen. Das Spektrum der an der Krebsentstehung beteiligten Gene und die Mechanismen ihrer Störung sind breit. Dies resultiert aus der Vielfältigkeit von Genen und Gensystemen, welche die Zellteilung und Differenzierung in verschiedenen Geweben kontrollieren. Angesichts aller Unterschiede in der Diagnostik und der Behandlung der verschiedenen Formen von Krebs eignen sich die genetischenAspekte der Krebsentstehungals Grundlage für das Verständnis. Diese Einführung zum „Handbuch der molekularen Medizin“, Band 9 und 10 über Tumorerkrankungen, soll die Orientierung erleichtern.

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Authors and Affiliations

  1. Institut für Humangenetik, Universitätsklinikum Essen, Hufelandstraße 55, 45122, Essen

    Prof. Dr. Eberhard Passarge

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  1. Prof. Dr. Eberhard Passarge
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Editors and Affiliations

  1. Max-Delbrück-Centrum für Molekulare Medizin (MDC), Robert-Rössle-Str. 10, 13122, Berlin-Buch

    Detlev Ganten  & Klaus Ruckpaul  & 

  2. Medizinische Universitätsklinik, Knappschaftskrankenhaus, In der Schornau 23-25, 44892, Bochum-Langendreer

    Stephan A. Hahn  & Wolff Schmiegel  & 

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© 2001 Springer-Verlag Berlin Heidelberg

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Passarge, E. (2001). Tumorerkrankungen — Einführung aus genetischer Sicht. In: Ganten, D., Ruckpaul, K., Hahn, S.A., Schmiegel, W. (eds) Molekularmedizinische Grundlagen von hereditären Tumorerkrankungen. Molekulare Medizin. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-56889-3_1

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  • DOI: https://doi.org/10.1007/978-3-642-56889-3_1

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-63219-8

  • Online ISBN: 978-3-642-56889-3

  • eBook Packages: Springer Book Archive

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