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A Complete Genomic DNA Sequence of Marek’s Disease Virus Type 2, Strain HPRS24

  • Chapter
Marek’s Disease

Part of the book series: Current Topics in Microbiology and Immunology ((CT MICROBIOLOGY,volume 255))

Abstract

Marek’s disease (MD) is a contagious lymphoproliferative disorder of chickens, and has been a major cause of poultry mortality in many countries since the 1960s. The causative agent of MD, a highly cell-associated herpesvirus called Marek’s disease virus (MDV), was isolated (Bankowski et al. 1969; Churchill and Biggs 1967,Churchill and Biggs 1968; Nazerian et al. 1968; Solomon et al. 1968; Witter et al. 1969) and live vaccines were developed by serial passages in cultured cells (Churchill et al. 1969a,Churchill et al.1969b) or by use of apathogenic herpesvirus isolated from turkeys (Kawamura et al. 1969; Okazaki et al. 1970; Witter et al. 1970). At present, vaccines derived from all three serotypes offer different levels of protection against the disease, either alone or in bivalent and trivalent combinations (Calnek and Witter 1997).

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Authors and Affiliations

  1. Department of Veterinary Microbiology, Faculty of Agriculture, The University of Tokyo, 1-1-1 Yayoi, Bunkyo-ku, Tokyo, 113-8657, Japan

    Y. Izumiya

  2. Department of Microbiology and Immunology, Louisiana State University Health Sciences Center, 1501 Kings’ Highway, Shreveport, LA, 71130-3932, USA

    H.-K. Jang

  3. Biomedical Research Laboratories, Sankyo Co. Ltd., 1-2-58 Hiromachi, Shinagawa-ku, Tokyo, 140-0005, Japan

    M. Ono

  4. The National Research Center for Protozoan Disease, Obihiro University of Agriculture and Veterinary Medicine, Nishi 2 Inada-cho, Obihiro, 080-8555, Japan

    T. Mikami

Authors
  1. Y. Izumiya
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  2. H.-K. Jang
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  3. M. Ono
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  4. T. Mikami
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Editor information

Editors and Affiliations

  1. Department of Tumor Virology, Medical Research Institute, Tokyo Medical and Dental University, Yushima 1-5-45, Bunkyo-ku, 113-8510, Tokyo, Japan

    Kanji Hirai

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© 2001 Springer-Verlag Berlin Heidelberg

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Izumiya, Y., Jang, HK., Ono, M., Mikami, T. (2001). A Complete Genomic DNA Sequence of Marek’s Disease Virus Type 2, Strain HPRS24. In: Hirai, K. (eds) Marek’s Disease. Current Topics in Microbiology and Immunology, vol 255. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-56863-3_8

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  • DOI: https://doi.org/10.1007/978-3-642-56863-3_8

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-63217-4

  • Online ISBN: 978-3-642-56863-3

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