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Molekularmedizinische Grundlagen von Endokrinopathien pp 223–257Cite as

Diabetes mellitus

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Part of the book series: Molekulare Medizin ((MOLMED))

Zusammenfassung

Der Diabetes mellitus ist die häufigste endokrinmetabolische Erkrankung und betrifft etwa 5% der westlichen Bevölkerung. Spätkomplikationen in Form der Mikro-und Makroangiopathie stellen ein großes gesundheitspolitisches Problem dar. Der Diabetes ist einer der häufigsten Ursachen in Deutschland für die Erblindung, den Einsatz des Nierenersatzverfahrens sowie für die Amputation der unteren Gliedmaßen. Patienten mit Diabetes mellitus entwickeln aber nicht nur mikroangiopathische Gefäßkomplikationen, sondern haben auch ein etwa 3-bis 5fach erhöhtes kard iovaskuläres Risiko. Ziel dieses Beitrages ist es u. a., Beispiele einiger molekularer Prinzipien zu geben, die zurzeit Gegenstand der klinischen Grundlagenforschung sind und wahrscheinlich auch in der Zukunft von klinischer Bedeutung für die Pathophysiologie Diagnostik und Therapie der häufigsten Diabetesformen sind.

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Authors
  1. Dirk Müller-Wieland
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  2. Hans-Ulrich Häring
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Editors and Affiliations

  1. Max-Delbrück-Centrum für Molekulare Medizin (MDC), Robert-Rössle-Str. 10, 13122, Berlin-Buch, Deutschland

    Detlev Ganten  & Klaus Ruckpaul  & 

  2. Abteilung für Endokrinologie, Universitätsklinikum Essen Zentrum für Innere Medizin, Hufelandstraße 55, 45122, Essen, Deutschland

    Onno E. Janssen

  3. Zentrum für Innere Medizin Abteilung Endokrinologie und Diabetologie, Klinikum der Philipps-Universität, Baldingerstraße/Lahnberge, 35033, Marburg, Deutschland

    Armin E. Heufelder

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Müller-Wieland, D., Häring, HU. (2001). Diabetes mellitus. In: Ganten, D., Ruckpaul, K., Janssen, O.E., Heufelder, A.E. (eds) Molekularmedizinische Grundlagen von Endokrinopathien. Molekulare Medizin. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-56858-9_7

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  • DOI: https://doi.org/10.1007/978-3-642-56858-9_7

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-63216-7

  • Online ISBN: 978-3-642-56858-9

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