Abstract
Oxygen derived free radicals are produced within the body’s cells by electron transfer reactions usually catalysed by enzymes or transition metal ions, or by ultraviolet or other types of radiation. Afree radical may be defined as any species (atom or molecule) capable of independent existence that contains one or more unpaired electrons. An unpaired electron is one that occupies an atomic or molecular orbital by itself and the presence of these unpaired electrons is often associated with increased chemical reactivity, since electrons have an in-built tendency to associate in pairs. Examples of free radicals include the superoxide radical (O −2 ) formed in all living cells exposed to oxygen, and the highly reactive hydroxyl radical (OH•), produced from superoxide in the presence of hydrogen peroxide and ‘free’ (i. e., not protein-bound) transition metal ions.
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Diplock, A. (2001). Antioxidants, Nutrition and Health. In: Ransley, J.K., Donnelly, J.K., Read, N.W. (eds) Food and Nutritional Supplements. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-56623-3_5
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DOI: https://doi.org/10.1007/978-3-642-56623-3_5
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