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Pore-Forming Toxins pp 35–52Cite as

Aerolysin from Aeromonas hydrophila and Related Toxins

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Part of the book series: Current Topics in Microbiology and Immunology ((CT MICROBIOLOGY,volume 257))

Abstract

Aeromonads are ubiquitous gram-negative bacteria found in aqueous environments. Some members of the genus are pathogenic for fish, reptiles and cows. In humans, Aeromonas infection is mainly associated with grastrointestinal diseases, but in immuno-compromised individuals infection can lead to septicemia and meningitis (Austin et al. 1996). Aeromonas secretes a variety of virulence factors amongst which aerolysin is the best characterized. Using marker exchange mutagenesis, aerolysin was demonstrated to be required not only for the establishment but also for the subsequent maintenance of systemic infections associated with the bacterium (Chakraborty et al. 1987). Furthermore, specific neutralizing antibodies to aerolysin have been detected in animals surviving Aeromonas infection.

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Authors and Affiliations

  1. Department of Biochemistry, Faculty of Sciences, University of Geneva, 30 Quai Ernest-Ansermet, 1211, Geneva, Switzerland

    M. Fivaz, L. Abrami, Y. Tsitrin & F. G. van der Goot

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  1. M. Fivaz
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  2. L. Abrami
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  3. Y. Tsitrin
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  4. F. G. van der Goot
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Editors and Affiliations

  1. Departement de Biochimie Sciences II, Quai Ernest-Ansermet, 1211, Genéve 4, Switzerland

    F. Gisou van der Goot

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© 2001 Springer-Verlag Berlin Heidelberg

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Fivaz, M., Abrami, L., Tsitrin, Y., van der Goot, F.G. (2001). Aerolysin from Aeromonas hydrophila and Related Toxins. In: van der Goot, F.G. (eds) Pore-Forming Toxins. Current Topics in Microbiology and Immunology, vol 257. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-56508-3_3

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  • DOI: https://doi.org/10.1007/978-3-642-56508-3_3

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