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Titanium in Medicine pp 649–671Cite as

Titanium Ceramics for Cell-Carriers and for Medical Applications

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Part of the book series: Engineering Materials ((ENG.MAT.))

Abstract

The high biocompatibility of titanium is useful not only in load-bearing implants, but also in implants which are intended to stimulate metabolic responses, such as implantable cell-carriers, and also in cell-culture substrates for in vitro culture and tissue engineering. A potential application is transplantation of liver cells. Implant-able cell-carriers which should serve to transplant liver cells into a diseased organism require the use of materials which do not induce the formation of a dense fibrous tissue capsule at the implantation site. Such a dense capsule formation would cut off transplanted cells from their nutrition supply with a fatal outcome for the cells. Moreover, as an implant can lead to neoformation of blood vessels [1] the carrier material should be of the highest biocompatibility to enable the ongrowth of vascularized, healthy tissue which can establish a long-term vascular supply for transplanted cells.

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Author information

Author notes

  1. Karl-Ludwig Eckert (Chair of Biocompatible Materials Science and Engineering)

    Present address: JOMED AG, Ampthauptstrasse, CH-8222, Beringen, Switzerland

Authors and Affiliations

  1. Zentralinstitut für Medizintechnik der TU München, Boltzmannstrasse 15, D-85748, Garching, Germany

    Erich Wintermantel (Chair of Biocompatible Materials Science and Engineering)

  2. Department of Materials, Laboratory for Surface Science and Technology, Swiss Federal Institute of Technology (ETH), Zurich, Switzerland

    Ning-Ping Huang & Marcus Textor

  3. Department of Oral Biological and Medical Sciences, University of British Columbia, Vancouver, BC, Canada

    Donald M. Brunette

Authors
  1. Erich Wintermantel
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  2. Karl-Ludwig Eckert
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  3. Ning-Ping Huang
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  4. Marcus Textor
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  5. Donald M. Brunette
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© 2001 Springer-Verlag Berlin Heidelberg

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Wintermantel, E., Eckert, KL., Huang, NP., Textor, M., Brunette, D.M. (2001). Titanium Ceramics for Cell-Carriers and for Medical Applications. In: Titanium in Medicine. Engineering Materials. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-56486-4_19

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  • DOI: https://doi.org/10.1007/978-3-642-56486-4_19

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-63119-1

  • Online ISBN: 978-3-642-56486-4

  • eBook Packages: Springer Book Archive

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