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Radiation Therapy Principles for High-Grade Gliomas

  • Chapter
Combined Modality Therapy of Central Nervous System Tumors

Part of the book series: Medical Radiology ((Med Radiol Radiat Oncol))

  • 177 Accesses

Abstract

Gliomas are the most common primary brain tumors,comprising 40-60% of all primary brain tumors.The most frequent types are glioblastoma multiforme, astrocytoma, and oligodendroglioma. Radiation therapy is one of the most important treatment modalities for gliomas, mainly because these tumors are usually localized. The patient¡¯s head can be immobilized, allowing for good targeting of the tumor. As a result of technological advances, the range of treatment options using radiation therapy has increased. Photon, electron, neutron and proton radiation beams are all in clinical use. The accuracy of the treatment delivery has also improved, with the development of three-dimensional techniques and image fusion. Our understanding of both the radio sensitivity of gliomas, and the tolerance of normal brain tissue is better, allowing the design of novel fractionation schemes. Radiation is being combined with both local and systemic chemotherapy, offering

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Authors and Affiliations

  1. Department of Radiation Oncology, The Brain Tumor Center, M.S. 200, MCP Hahnemann University, 216 North Broad Street, Philadelphia

    C. Miyamoto MD (Associate Professor and Clinical Service Chief)

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  1. C. Miyamoto MD
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Editors and Affiliations

  1. Department of Radiation Oncology, University of Southern California, Keck School of Medicine 1441 Eastlake Avenue, Room G356, Los Angeles, CA, 90033-0804, USA

    Zbigniew Petrovich MD, FACR (Professor and Chairman) (Professor and Chairman)

  2. Department of Radiation Oncology, Hahnemann University Hospital, Broad & Vine Sts., Mail Stop 200, Philadelphia, PA, 19102, USA

    Luther W. Brady MD (Hylda Cohn/ American Cancer Society Professor of Clinical Oncology and Professor) (Hylda Cohn/ American Cancer Society Professor of Clinical Oncology and Professor)

  3. Keck School of Medicine of the University of Southern California, Los Angeles, CA, 90033, USA

    Michael L. J. Apuzzo MD (Edwin M. Todd/Trent H. Wells, Jr. Professor of Neurological Surgery and Professor of Radiation Oncology) (Edwin M. Todd/Trent H. Wells, Jr. Professor of Neurological Surgery and Professor of Radiation Oncology)

  4. Department of Radiotherapy, Eberhard-Karls-Universität, Hoppe-Seyler-Strasse 3, 72076, Tübingen, Germany

    Michael Bamberg MD

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Miyamoto, C. (2003). Radiation Therapy Principles for High-Grade Gliomas. In: Petrovich, Z., Brady, L.W., Apuzzo, M.L.J., Bamberg, M. (eds) Combined Modality Therapy of Central Nervous System Tumors. Medical Radiology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-56411-6_18

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  • DOI: https://doi.org/10.1007/978-3-642-56411-6_18

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-00627-5

  • Online ISBN: 978-3-642-56411-6

  • eBook Packages: Springer Book Archive

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