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Identification of Cell Targeting Ligands Using Random Peptide-Presenting Phage Libraries

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Genetic Library Construction and Screening

Part of the book series: Springer Lab Manuals ((SLM))

Abstract

Phage display is a powerful technique for identifying peptides or proteins that bind to particular targets. The technique first described by (1985), allows among other applications, rapid screening of random peptide libraries expressed on the surface of filamentous bacteriophage for ligands that can then be used for diagnostic and therapeutic needs.

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© 2002 Springer-Verlag Berlin Heidelberg

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Samoylova, T.I., Smith, B.F. (2002). Identification of Cell Targeting Ligands Using Random Peptide-Presenting Phage Libraries. In: Bird, R.C., Smith, B.F. (eds) Genetic Library Construction and Screening. Springer Lab Manuals. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-56408-6_11

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  • DOI: https://doi.org/10.1007/978-3-642-56408-6_11

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-47733-1

  • Online ISBN: 978-3-642-56408-6

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