Skip to main content
SpringerLink
Log in

Chronisch-lymphatische Leukämie

  • Chapter
Geriatrische Onkologie

  • 85 Accesses

Zusammenfassung

Chronisch lymphatische Leukämien sind lymphozytische Non-Hodgkin-Lymphome, die in den meisten Fällen leukämisch verlaufen. Bei ihnen kommt es ohne Zunahme der Proliferationsrate zu einer progressiven Akkumulation der leukämischen Lymphozyten durch Behinderung der Apoptose.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 149.00
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

Literatur

  • Binet JL, Auquier A, Dighiero G et al. (1981) A new prognostic classification of chronic lymphocytic leukemia derived from a multivariate survival analysis. Cancer 48: 198–206

    Article  PubMed  CAS  Google Scholar 

  • Cheson BD, Bennett JM, Raik KR, Grever MR, Kay NE, Schiffer CA, Oken MM, Keating MJ, Boldt DH, Kempin SJ (1988) Guidelines for clinical protocols for chronic lymphocytic leukemia (CLL): recommendations of the NCI-Sponsored Working Group. Am J Hematol 29: 152–163

    Article  PubMed  CAS  Google Scholar 

  • Cheson BD, Bennett JM, Grever M, Kay N, Keating MJ, O’Brien S, Rai KR (1996) National Cancer Institute-sponsored working group guildelines for chronic lymphocytic leukemia: revised guidelines for diagnosis and treatment. Blood 87: 4990–4997

    PubMed  CAS  Google Scholar 

  • Cooperative Group for the Study of Immunoglobulin in chronic lymphocytic leukemia (1988) Intraveneous immunoglobulin for the prevention of infection in chronic lymphocytic Leukemia. N Engl J Med 319: 902–906

    Article  Google Scholar 

  • Emmrich B, Hallek M (1999) Chronisch lymphatische Leukämie. In: Schmoll HJ, Höffken K, Possinger K (Hrsg) Kompendium Internistische Onkologie, Bd 2. Springer, Berlin Heidelberg New York, S 208–242

    Google Scholar 

  • Foon KA, Rai KR, Gale RP (1990) Chronic lymphocytic leukemia: new insights into biology and therapy (review). Ann Int Med 113: 525–539

    PubMed  CAS  Google Scholar 

  • Hernandes JA, Land KJ, Mekenna RW (1995) Leukemias, myeloma and other lymphoreticular neoplasms. Cancer 75: 381–394

    Article  Google Scholar 

  • International Workshop on Chronic lymphocytic Leukemia (1989) Recommendations for diagnosis, staging and response criteria. Ann Intern Med 110: 236–238

    Google Scholar 

  • Molica S, Brugiatelli M, Callea V, Morabito F, Levato D, Nobile F, Alberti A (1994) Comparison of younger versus older B-cell chronic lymphocytic leukemia patients for clinical presentation and prognosis: a retrospective study of 53 cases. Eur J Haematol 52: 216–221

    Article  PubMed  CAS  Google Scholar 

  • Montserrat E (1997) New therapeutic issues in CLL. Hematol Cell Ther 39: 45–49

    Article  Google Scholar 

  • Montserrat E, Vindas N, Reverter JC, Rozman C (1988) Natural history of chronic lymphocytic leukemia: on the progression and prognosis of early clinical stages. Nouv Rev Fr Hematol 33: 359–361

    Google Scholar 

  • Montserrat E, Gomis F, Vallespi T, Rios A, Romero A, Solen J, Alcala A, Morey A, Ferran C, Diaz-Mediavilla A (1991) Presenting features and prognosis of chronic lymphocytic leukemia in younger adults. Blood 78: 1545–1551

    PubMed  CAS  Google Scholar 

  • Osterborg A, Fassus AS, Anagnostopoolos A, Dyer MJ, Catovski D, Mellstedt H (1996) Humanised CD 52 monoclonal antibody Campath-1 H as first-line treatment in chronic lymphocytic leukemia. Br J Haematol 93: 151–153

    Article  PubMed  CAS  Google Scholar 

  • Osterborg A, Dyer MJ, Bunjies D, Pangalis GA, Bastion Y, Catovsky D, Mellstedt H (1997) Phase II multicenter study of human CD 52 antibody in previonsly treated chronic lymphocytic leukemia. J Clin Oncol 15: 1567–1574

    PubMed  CAS  Google Scholar 

  • Rai KR (1987) A critical analysis of staging in CLL. In: Gale RP, Rai KR (eds) Chronic lymphocytic leukemia: recent progress and future directions. UCLA Symposia on molecular and cellular biology, new series, vol 59. Liss, New York, p 253

    Google Scholar 

  • Rai RR, Sawitzsky A, Cronkite EP, Chanana AD, Levy RN, Pasternack BS (1975) Clinical staging of chronic lymphocytic leukemia. Blood 46: 219–234

    PubMed  CAS  Google Scholar 

Download references

Authors
  1. H.-J. Fricke
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. K. Höffken
    View author publications

    You can also search for this author in PubMed Google Scholar

Editor information

Editors and Affiliations

  1. Klinik und Poliklinik für Innere Medizin II, Friedrich-Schiller-Universität Jena, Erlanger Allee 101, D-07747, Jena, Germany

    Klaus Höffken  & Ulrich Wedding  & 

  2. St. Bonifatius-Hospital, Wilhelmstraße 3, D-49808, Lingen, Germany

    Gerald Kolb

Rights and permissions

Reprints and permissions

Copyright information

© 2002 Springer-Verlag Berlin Heidelberg

About this chapter

Cite this chapter

Fricke, HJ., Höffken, K. (2002). Chronisch-lymphatische Leukämie. In: Höffken, K., Wedding, U., Kolb, G. (eds) Geriatrische Onkologie. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-56391-1_23

Download citation

  • DOI: https://doi.org/10.1007/978-3-642-56391-1_23

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-63154-2

  • Online ISBN: 978-3-642-56391-1

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics

Search

Navigation