Skip to main content

Fibrinolyse bei akuter Erblindung — Ergebnisse der Mikrokathetertechnik

  • Chapter
Book cover Medizin im 21. Jahrhundert

Zusammenfassung

Bei einem nichtentzündlichen Zentralarterienverschluss (ZAV) mit plötzlicher hochgradiger Sehminderung bzw. Erblindung, charakterisiert durch ein Ödem der zentralen Netzhaut, einen „kirschroten Fleck“ der Makula und eine herabgesetzte Blutströmung retinaler Arterien und Venen (unterbrochene Blutsäule bzw. körnelige Strömung, Verengung des arteriellen Lumens, deutliche Kaliberunregelmäßigkeiten auch der Venen; Abb. 1), ist die Prognose für das Sehvermögen schlecht, wenn keine Behandlung erfolgt. Ein derart geschädigtes Auge bleibt im Falle eines subtotalen oder vollständigen ZAV blind bzw. weist eine hochgradige Sehminderung auf.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 49.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 69.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

Literatur

  • Appen RE, Wray SH, Cogan DG (1975) Central retinal artery occlusion. Am J OphthalmoI 79:374–381

    Google Scholar 

  • Arruga J, Sanders MD (1982) Ophthalmologic findings in 70 patients with evidence of retinal embolism. Ophthalmology 89:1336–1347

    Google Scholar 

  • Atebara NH, Brown GC, Cater J (1995) Efficacy of anterior chamber paracentesis and carbogen in treating acute nonarteritic central retinal artery occlusion. Ophthalmology 102:2029–2035

    Google Scholar 

  • Atlee WE (1972) Tale and cornstarch emboli in eyes of drug abusers. JAMA 219:49–51

    Google Scholar 

  • Augsburger JJ, Magargal LE (1980) Visual prognosis following treatment of acute central retinal artery obstruction. Br J OphthalmoI 64:913–917

    Google Scholar 

  • Barth H, Stein H, Fasse A, Mehdorn HM (1996) Intrazerebrale Blutung nach systemischer Thrombolyse bei Patienten mit Verschluß der A. centralis retinae. Ophthalmologe 93:739–744

    Google Scholar 

  • Beiran I, Reissman P, Scharf J, Nahum Z, Miller B (1993) Hyperbaric oxygenation combined with nifedipine treatment for re cent-on set retinal artery occlusion. Eur J Ophthalmol 3:89–94

    Google Scholar 

  • Brown GC, Magargal LE, Sergott R (1986) Acute obstruction of the retinal and choroidal circulations. Ophthalmology 93:1373–1382

    Google Scholar 

  • Brunner S, Arbesser M (1999) Fibrinolytische Therapie bei Zentralarterien- und Arterienastverschlüssen des Auges. Spektr Augenheilkd 13: 109–114

    Google Scholar 

  • Chen JC, Cheema D (1994) Repeated anterior chamber paracentesis for the treatment of central retinal artery occlusion. Can J OphthalmoI 29:207–209

    Google Scholar 

  • Dahrling BE (1965) The histopathology of early central retinal artery occlusion. Arch Ophthalmol 73:506–510

    Google Scholar 

  • David NI, Norton EWD, Gass JD, Beauchamp J (1967) Fluorescein angiography in central retinal artery occlusion. Arch Ophthalmol 77:619–629

    Google Scholar 

  • Duker JS, Sivalingam A, Brown GC, Reber R (1991) A prospective study of acute central retinal artery obstruction. The incidence of secondary ocular neovascularization. Arch Ophthalmol 109:339–342

    Google Scholar 

  • Elschnig A (1892) Ueber die Embolie der Arteria centralis retinae. Arch Augenheilk 24:65–146

    Google Scholar 

  • Ffytche TJ (1974) A rationalization of treatment of central retinal artery occlusion. Trans Ophthalmol Soc UK 94:468–479

    Google Scholar 

  • Friberg TR, Gragoudas ES, Regan CDJ (1979) Tale emboli and macular ischemia in intravenous drug abuse. Arch Ophthalmol 97:1089–1091

    Google Scholar 

  • Garron LK (1952) Dissecting aneurysm of the central retinal artery. A preliminary report. Transactions of the Pacific Co ast Oto-Ophthalmology Society 33:157–171

    Google Scholar 

  • Gass JDM (1968) A fluorescein angiographic study of macular dysfunction secondary to retinal vascuIar disease. Arch Ophthalmol 80:535–549

    Google Scholar 

  • Gloor B, Müller HR, Vozenilek E (1985) Arterielle Verschlußkrankheit im Augenbereich. Diagnostischer Beitrag der Dopplersonographie. Klin Mbl Augenheilk 186:161–171

    Google Scholar 

  • Goldstein I, Wexler D (1933) Embolism of the central retinal and ciliary arteries. In a case of chronic lipoid nephrosis with thrombosis of the innominate artery. Arch OphthalmoI 10:70–75

    Google Scholar 

  • Gowers WR (1875) Simultaneous embolism of central retinal and middle cerebral arteries. Lancet 2:794–796

    Google Scholar 

  • Graefe A von (1859) Ueber Embolie der Arteria centralis retinae als Ursache plötzlicher Erblindung. Graefes Arch Ophthalmol 5:136–157

    Google Scholar 

  • Greven CM, Slusher MM, Weaver RG (1995) Retinal arterial occlusions in young adults. Am J OphthalmoI 120:776–783

    Google Scholar 

  • Hayreh SS (1971) Pathogenesis of occlusion of the central retinal vessels. Am J Ophthalmol 72:998–1010

    Google Scholar 

  • Hayreh SS, Kolder HE, Weingeist TA (1980) Central retinal artery occlusion and retinal tolerance time. Ophthalmology 87:75–78

    Google Scholar 

  • Hollenhorst RW (1966) Vascular status of patients who have cholesterol emboli in the retina. Am J OphthalmoI 61:1159–1165

    Google Scholar 

  • Karjalainen K (1971) Occlusion of the central retinal artery and retinal branch arterioles. A clinica!, tonographic and fluorescein angiographic study of 175 patients. Acta Ophthalmol Scand Suppl 109:9–96

    Google Scholar 

  • Kase CS, O’Neal AM, Fisher M, Girgis GN, Ordia JI (1990) Intracranial hemorrhage after use of tissue plasminogen activator for coronary thrombolysis. Ann Intern Med 112:17–21

    Google Scholar 

  • Kroll AJ (1968) Experimental central retinal artery occlusion. Arch Ophthalmol 79:453–469

    Google Scholar 

  • Lansche RK (1965) Central retinal artery occlusion. Am J OphthalmoI 60:716–719

    Google Scholar 

  • Lee J, Sapira JD (1973) Retinal and cerebral microembolization of tale in a drug abuser. Am J Med Sei 265:75–77

    Google Scholar 

  • Mangat HS, Kline LB, Brandt BM, Kimble JA, Tang R, Slavin M (1995) Retinal artery occlusion. Surv OphthalmoI40:145–156

    Google Scholar 

  • McBrien DJ, Bradley RD, Ashton N (1963) The nature of retina! emboli in stenosis of the internal carotid artery. Lancet 1 :697–699

    Google Scholar 

  • McLeod D (1976) Ophthalmoscopic signs of obstructed axoplasmic transport after ocular vascular occlusions. Br J OphthalmoI 60:551–556

    Google Scholar 

  • Nettleship E (1874) Embolism of central artery of retina. Microscopic examination. Ophthalmie Rep 8:9–20

    Google Scholar 

  • Perkins SA, Magargal LE, Augsburger n, Sanborn GE (1987) The idling retina: reversible visual loss in central retinal artery obstruction. Ann Ophthalmol 19:3–6

    Google Scholar 

  • Richard G, Lerche RC, Knospe V, Zeumer H (1999) Treatment of retinal arte rial occlusion with local fibrinolysis using recombinant tissue plasminogen activator. Ophthalmology 106:768–773

    Google Scholar 

  • Ross Russell RW, Ffytche TJ, Sanders MD (1966) A study of retinal vascular occlusion using fluorescein angiography. Lancet 2:821–825

    Google Scholar 

  • Rumelt S, Dorenboim Y, Rehany U (1999) Aggressive systematic treatment for central retinal artery occlusion. Am J OphthalmoI 128:733–738

    Google Scholar 

  • Schinzel H, Kern M, Kelbel C, Weilemann LS, Benning H, Grehn F (1992) Fibrinolytische Therapie bei akuten Zentralarterienverschlüssen des Auges. Intensivmed 29:170–172

    Google Scholar 

  • Schmidt D (1996) The incomplete central retinal artery occlusion (ICRAO). Visual recovery with conservative therapy. Neuro-Ophthalmology 16: 171–182

    Google Scholar 

  • Schmidt D, Schumacher M (1991) Zur Therapie des Zentralarterienverschlusses. Tagung der Berliner Augenärztlichen Gesellschaft (1./2.12.1990). Klin Mbl Augenheilk 199:380

    Google Scholar 

  • Schmidt D, Schumacher M (1998) Stage-dependent efficacy of intra-arterial fibrinolysis in central retinal artery occlusion (CRAO). Neuro-Ophthalmology 20:125–141

    Google Scholar 

  • Schmidt D, Schumacher M (1999) Lokale intraarterielle Fibrinolyse bei Zentralarterienverschluß (intra-arterial fibrinolysis in 51 patients with central retinal artery occlusion). Z Prakt Augenheilkd 20:205–212

    Google Scholar 

  • Schmidt D, Zehender M (1999) Arterienverschluß des Auges bei infektiöser Endokarditis. Ophthalmologe 96:264–266

    Google Scholar 

  • Schmidt D, Richter T, Reutern GM von, Engelhardt R (1991) Akute Durchblutungsstörungen des Auges. Klinische Befunde und Ergebnisse der DopplerSonographie der A. carotis interna. Fortsehr Ophthalmol 88:84–98

    Google Scholar 

  • Schmidt D, Schumacher M, Wakhloo AK (1992) Microcatheter urokinase infusion in central retinal artery occlusion. Am J Ophthalmol 113:429–434

    Google Scholar 

  • Schmidt D, Janknecht P, Wiek J (1995) Incomplete central retinal artery occlusion (CRAO). A fluorescein-angiography investigation with the scanning-laserophthalmoscope (SLO). Vision Res 35 (Suppl):SI28

    Google Scholar 

  • Schmidt D, Schumacher M, Mittelviefhaus K (1997) Visual recovery after acute choroidal ischemia with partial retinal hypoperfusion, demonstrated by fluorescein angiography. Neuro-Ophthalmology 18:205–213

    Google Scholar 

  • Schmidt D, Hetzel A, Geibel-Zehender A (2000) Retinaler Arterienverschluß bei Vorhofmyxom. Klin Mbl Augenheilk 217 (SuppI8):7–8

    Google Scholar 

  • Schmidt H (1874) Beitrag zur Kenntnis der Embolie der Arteria centralis retinae. Graefes Arch OphthalmoI 20:287–307

    Google Scholar 

  • Schumacher M, Schmidt D (1995) Local fibrinolysis in central retinal artery occlusion: follow-up in 36 cases. In: Takahashi M, Korogi Y, Moseley I (eds) Proceedings of the XV. Symposium on Neuroradiology in Kumamoto, September October 1994. Springer, Berlin Heidelberg New York Tokyo, pp 458–460

    Google Scholar 

  • Schumacher M, Schmidt D, Wakhloo AK (1991) Intraarterielle Fibrinolyse bei Zentralarterienverschluß. Radiologe 31 :240–243 So chor GE, Daniel F, Decrinis N, Pilger E (1994) Fibrinolyse (rt-PA) als Therapie bei akuten retinalen Arterienverschlüssen. Spektr Augenheilkd 8:176–178

    Google Scholar 

  • Tsai FY, Wadley D, Angle JF, Alfieri K, Byars St (1990) Superselective ophthalmie angiography for diagnostic and therapeutic use. AJNR 11:1203–1204

    Google Scholar 

  • Vulpius K, Höh H, Lange H, Maercker W, Rühle H (1996) Selektive perkutane transluminale Lysetherapie mit RTPA bei retinalem Zentralarterienverschluß. Ophthalmologe 93:149–153

    Google Scholar 

  • Weber J, Remonda L, Mattle HP et al. (1998) Selective intra-arterial fibrinolysis of acute central retinal artery occlusion. Stroke 29:2076–2079

    Google Scholar 

  • Wiegand W, Siegert 1, Scholz R, Kroll P (1991) Lysetherapie bei Zentralarterienverschlüssen. Sitzungsbericht 153. Vers Verein RW Augenärzte: 383–389

    Google Scholar 

  • Wolf S, Hoberg A, Bertram B, Jung F, Kiesewetter H, Reim M (1989) Videofluoreszenzangiographische VerIaufsbeobachtungen bei Patienten mit retinalen Arterienverschlüssen. Klin Mbl Augenheilk 195: 154–160

    Google Scholar 

  • Wolter JR, Hansen KD (1981) Intimo-intimal intussusception of the central retinal artery. Am J Ophthalmol 92:486–491

    Google Scholar 

  • Wolter JR, Liddicoat DA (1958) Secondary glaucoma following occlusion of the central artery of the retina. Am J OphthalmoI 46:182–186

    Google Scholar 

  • Wolter JR, Phillips RL (1959) Secondary glaucoma following occlusion of the central retinal artery. Am J OphthalmoI 47:335–340

    Google Scholar 

  • Wolter JR, Ryan RW (1972) Atheromatous embolism of the central retinal artery. Secondary hemorrhagic glaucoma. Arch Ophthalmol 87:301–304

    Google Scholar 

  • Würdemann HV (1920) Embolism of central artery of retina. Restoration by forcible massage. Am J OphthalmoI 3:513–514

    Google Scholar 

  • Zeumer H, Freitag HJ, Grzyska U, Neunzig HP (1989) Local intraarterial fibrinolysis in acute vertebrobasilar occlusion. Technical deve10pments and recent results. Neuroradiology 31:336–340

    Google Scholar 

  • Zimmerman LE (1965) Embolism of central retinal artery secondary to myocardial infarction with mural thrombosis. Arch Ophthalmol 73:822–826

    Google Scholar 

Download references

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2002 Springer-Verlag Berlin Heidelberg

About this chapter

Cite this chapter

Schmidt, D., Schumacher, M. (2002). Fibrinolyse bei akuter Erblindung — Ergebnisse der Mikrokathetertechnik. In: Laubach, E., Mau, F., Mau, T. (eds) Medizin im 21. Jahrhundert. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-56302-7_10

Download citation

  • DOI: https://doi.org/10.1007/978-3-642-56302-7_10

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-42321-8

  • Online ISBN: 978-3-642-56302-7

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics