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Thrombolysetherapie des akuten Herzinfarktes

  • Chapter
Notfallbehandlung des akuten Koronarsyndroms

Zusammenfassung

Berücksichtigt man ausschlieβlich die Daten groβer randomisierter Letalitätsstudien, so scheint der akute Myokardinfarkt dank der modernen Medizin seinen Schrecken weitgehend verloren zu haben [1–3]. Trotz tendenziellem Rückgang in den letzten 20 Jahren stellt der akute Herzinfarkt jedoch auch heute noch eine der häufigsten Todesursachen dar [4–6]. Fast die Hälfte der Betroffenen verstirbt in der Akutphase bereits vor dem Eintreffen medizinischer Hilfe am arrhythmogenen Sekundenherztod, aber auch wenn die Patienten ein Krankenhaus erreichen, liegt die Gesamtsterblichkeit weiterhin - im Gegensatz zu den Daten multizentrischer Studien - bei mehr als 15–20% [4,6]. Da die verbleibende Myokardfunktion den primären Indikator für die Langezeitprognose der Infarktpatienten darstellt [7], sind die therapeutischen Bemühungen heute auf den Erhalt des Myokards gerichtet.

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Kusch, A., Lankes, W., Gulba, D.C. (2002). Thrombolysetherapie des akuten Herzinfarktes. In: Arntz, HR., Gulba, D.C., Tebbe, U. (eds) Notfallbehandlung des akuten Koronarsyndroms. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-56220-4_10

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