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Biosafety Issues in Lentivector Production

  • Chapter
Lentiviral Vectors

Part of the book series: Current Topics in Microbiology and Immunology ((CT MICROBIOLOGY,volume 261))

Abstract

The development of efficient lentivectors brings about exciting possibilities for novel therapeutic interventions. Still, as new biologicals intended to be used in the clinic, these vectors will have to comply with a complete set of requirements regarding their mode of preparation and characterization. Over the past 50 years, there has been an increasing awareness of the safety issues surrounding the manufacturing of medicinal products. Regulatory authorities and agencies regularly publish guidelines and coordinate international conferences on harmonization (ICH), whose goal is to define common standards for biotechnological and biological products to be administered to human patients (SCHULTZ 1998).

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    C. Delenda, M. Audit & O. Danos

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  2. M. Audit
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  1. Department of Genetics and Microbiology, Faculty of Medicine, University of Geneva, CMU; 1 rue Michel-Servet, 1211, Geneva 4, Switzerland

    Didier Trono

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Delenda, C., Audit, M., Danos, O. (2002). Biosafety Issues in Lentivector Production. In: Trono, D. (eds) Lentiviral Vectors. Current Topics in Microbiology and Immunology, vol 261. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-56114-6_6

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  • DOI: https://doi.org/10.1007/978-3-642-56114-6_6

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