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Influence of Mechanical Ventilation on Organ Dysfunction

  • Chapter
Mechanisms of Organ Dysfunction in Critical Illness

Part of the book series: Update in Intensive Care and Emergency Medicine ((UICMSOFT,volume 38))

  • 106 Accesses

Abstract

Mechanical ventilation (MV) is a central component in the care of the critically ill patient. Most patients who develop multiple organ failure (MOF) require mechanical ventilation as a life-supporting measure. In addition, a proportion of patients develop MOF after the initiation of mechanical ventilation. Although indispensable in these situations, there is clear evidence that MV itself can cause or worsen lung injury, and accumulating data supports the theory that it may also be a factor in initiating or exacerbating MOF.

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Authors and Affiliations

  1. Department of Critical Care, 30 Bond St Queen Wing, 4-042, Toronto, Ontario, M5B 1W8, Canada

    T. Whitehead & A. S. Slutsky

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  1. T. Whitehead
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  2. A. S. Slutsky
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Editors and Affiliations

  1. Intensive Care Unit, Royal Brompton Hospital, Sydney Street, London, SW3 6NP, UK

    Timothy W. Evans

  2. Division of Critical Care Medicine, University of Pittsburgh Medical Center, Scaife Hall, Room 606, 3550 Terrace Street, Pittsburgh, PA, 15264, USA

    Mitchell P. Fink

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© 2002 Springer-Verlag Berlin Heidelberg

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Whitehead, T., Slutsky, A.S. (2002). Influence of Mechanical Ventilation on Organ Dysfunction. In: Evans, T.W., Fink, M.P. (eds) Mechanisms of Organ Dysfunction in Critical Illness. Update in Intensive Care and Emergency Medicine, vol 38. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-56107-8_26

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  • DOI: https://doi.org/10.1007/978-3-642-56107-8_26

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-42692-9

  • Online ISBN: 978-3-642-56107-8

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