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Pathophysiologie der KHK und Wirkung der Östrogene

  • Elisabeth von der Lohe
Chapter
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Zusammenfassung

Die Atherosklerose der Koronargefäße bildet die pathophysiologische Grundlage der KHK und ist bei bei den Geschlechtern gleich. Es bestehen verschiedene Theorien über die Entstehung der Atherosklerose. Die meist vertretene ist die sog. Response-to-injury-Hypothese von R. Ross. Danach führen verschiedene Schädigungen des Endothels und der glatten Gefäßmuskelzellen zu einer überschießenden entzündlich-fibroproliferativen Reaktion der Gefäßwand und somit zur Ausbildung von Plaques.

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Copyright information

© Springer-Verlag Berlin Heidelberg 2002

Authors and Affiliations

  • Elisabeth von der Lohe
    • 1
  1. 1.Wishard Health ServicesKrannert Institute of CardiologyIndianapolisUSA

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