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Extraintestinal Escherichia coli as a Model System for the Study of Pathogenicity Islands

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Book cover Pathogenicity Islands and the Evolution of Pathogenic Microbes

Part of the book series: Current Topics in Microbiology and Immunology ((CT MICROBIOLOGY,volume 264/2))

Abstract

The extraintestinal Escherichia coli comprise one of at least six pathogenic subtypes of E. coli. The group includes strains causing kidney and bladder infections, as well as sepsis and meningitis. The morbidity associated with these E. coli is vast. The uropathogenic strains (UPEC) are responsible for 80% of urinary tract infections in outpatients, resulting in more than 8 million visits each year to physicians in the United States alone (Wenzel 1991). E. coli remain a leading cause of abscess and septic shock. The meningitis E. coli strains account for 30% of these infections in neonates, resulting in death in one of five cases despite treatment (De Louvois 1994).

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Authors
  1. P. Redford
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  2. R. A. Welch
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Editor information

Editors and Affiliations

  1. Institut für Molekulare Infektionsbiologie, Universität Würzburg, Röntgenring 11, 97070, Würzburg, Germany

    Jörg Hacker

  2. Center for Vaccine Development, University of Maryland School of Medicine, 685 W. Baltimore Street, 21201, Baltimore, MD, USA

    James B. Kaper

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© 2002 Springer-Verlag Berlin Heidelberg

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Redford, P., Welch, R.A. (2002). Extraintestinal Escherichia coli as a Model System for the Study of Pathogenicity Islands. In: Hacker, J., Kaper, J.B. (eds) Pathogenicity Islands and the Evolution of Pathogenic Microbes. Current Topics in Microbiology and Immunology, vol 264/2. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-56031-6_2

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  • DOI: https://doi.org/10.1007/978-3-642-56031-6_2

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-62720-0

  • Online ISBN: 978-3-642-56031-6

  • eBook Packages: Springer Book Archive

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